-
1
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL,. ras oncogenes in human cancer: a review. Cancer Res. 1989; 49: 4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
2
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J,. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer. 2003; 3: 11-22.
-
(2003)
Nat Rev Cancer.
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
3
-
-
0033014304
-
RAS and leukemia: From basic mechanisms to gene-directed therapy
-
Beaupre DM, Kurzrock R,. RAS and leukemia: from basic mechanisms to gene-directed therapy. J Clin Oncol. 1999; 17: 1071-1079.
-
(1999)
J Clin Oncol.
, vol.17
, pp. 1071-1079
-
-
Beaupre, D.M.1
Kurzrock, R.2
-
4
-
-
33646575624
-
Implications of NRAS mutations in AML: A study of 2502 patients
-
Bacher U, Haferlach T, Schoch C, Kern W, Schnittger S,. Implications of NRAS mutations in AML: a study of 2502 patients. Blood. 2006; 107: 3847-3853.
-
(2006)
Blood.
, vol.107
, pp. 3847-3853
-
-
Bacher, U.1
Haferlach, T.2
Schoch, C.3
Kern, W.4
Schnittger, S.5
-
5
-
-
0023160529
-
Mutations in N-ras predominate in acute myeloid leukemia
-
Bos JL, Verlaan-de Vries M, van der Eb AJ, et al. Mutations in N-ras predominate in acute myeloid leukemia. Blood. 1987; 69: 1237-1241.
-
(1987)
Blood.
, vol.69
, pp. 1237-1241
-
-
Bos, J.L.1
Verlaan-De Vries, M.2
Van Der Eb, A.J.3
-
6
-
-
24744449132
-
RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years
-
Bowen DT, Frew ME, Hills R, et al. RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years. Blood. 2005; 106: 2113-2119.
-
(2005)
Blood.
, vol.106
, pp. 2113-2119
-
-
Bowen, D.T.1
Frew, M.E.2
Hills, R.3
-
7
-
-
0028114788
-
The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia
-
Coghlan DW, Morley AA, Matthews JP, Bishop JF,. The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia. Leukemia. 1994; 8: 1682-1687.
-
(1994)
Leukemia.
, vol.8
, pp. 1682-1687
-
-
Coghlan, D.W.1
Morley, A.A.2
Matthews, J.P.3
Bishop, J.F.4
-
8
-
-
18244383283
-
Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts
-
Illmer T, Thiede C, Fredersdorf A, et al. Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts. Clin Cancer Res. 2005; 11: 3217-3224.
-
(2005)
Clin Cancer Res.
, vol.11
, pp. 3217-3224
-
-
Illmer, T.1
Thiede, C.2
Fredersdorf, A.3
-
9
-
-
0033134792
-
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia
-
Kiyoi H, Naoe T, Nakano Y, et al. Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood. 1999; 93: 3074-3080.
-
(1999)
Blood.
, vol.93
, pp. 3074-3080
-
-
Kiyoi, H.1
Naoe, T.2
Nakano, Y.3
-
10
-
-
0028214608
-
Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia
-
Neubauer A, Dodge RK, George SL, et al. Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood. 1994; 83: 1603-1611.
-
(1994)
Blood.
, vol.83
, pp. 1603-1611
-
-
Neubauer, A.1
Dodge, R.K.2
George, S.L.3
-
11
-
-
53749099948
-
Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: A Cancer and Leukemia Group B study
-
Neubauer A, Maharry K, Mrozek K, et al. Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. J Clin Oncol. 2008; 26: 4603-4609.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 4603-4609
-
-
Neubauer, A.1
Maharry, K.2
Mrozek, K.3
-
12
-
-
0024990090
-
N-ras mutations in adult de novo acute myelogenous leukemia: Prevalence and clinical significance
-
Radich JP, Kopecky KJ, Willman CL, et al. N-ras mutations in adult de novo acute myelogenous leukemia: prevalence and clinical significance. Blood. 1990; 76: 801-807.
-
(1990)
Blood.
, vol.76
, pp. 801-807
-
-
Radich, J.P.1
Kopecky, K.J.2
Willman, C.L.3
-
13
-
-
0035383768
-
FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia
-
Stirewalt DL, Kopecky KJ, Meshinchi S, et al. FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia. Blood. 2001; 97: 3589-3595.
-
(2001)
Blood.
, vol.97
, pp. 3589-3595
-
-
Stirewalt, D.L.1
Kopecky, K.J.2
Meshinchi, S.3
-
14
-
-
0031053856
-
N-ras gene point mutations in Brazilian acute myelogenous leukemia patients correlate with a poor prognosis
-
De Melo MB, Lorand-Metze I, Lima CS, Saad ST, Costa FF,. N-ras gene point mutations in Brazilian acute myelogenous leukemia patients correlate with a poor prognosis. Leuk Lymphoma. 1997; 24: 309-317.
-
(1997)
Leuk Lymphoma.
, vol.24
, pp. 309-317
-
-
De Melo, M.B.1
Lorand-Metze, I.2
Lima, C.S.3
Saad, S.T.4
Costa, F.F.5
-
15
-
-
0011134388
-
RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes
-
Janssen JW, Steenvoorden AC, Lyons J, et al. RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes. Proc Natl Acad Sci U S A. 1987; 84: 9228-9232.
-
(1987)
Proc Natl Acad Sci U S A.
, vol.84
, pp. 9228-9232
-
-
Janssen, J.W.1
Steenvoorden, A.C.2
Lyons, J.3
-
16
-
-
17344371122
-
RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: A 10-year follow-up
-
Padua RA, Guinn BA, Al-Sabah AI, et al. RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up. Leukemia. 1998; 12: 887-892.
-
(1998)
Leukemia.
, vol.12
, pp. 887-892
-
-
Padua, R.A.1
Guinn, B.A.2
Al-Sabah, A.I.3
-
17
-
-
0027181645
-
N-ras mutations are associated with poor prognosis and increased risk of leukemia in myelodysplastic syndrome
-
Paquette RL, Landaw EM, Pierre RV, et al. N-ras mutations are associated with poor prognosis and increased risk of leukemia in myelodysplastic syndrome. Blood. 1993; 82: 590-599.
-
(1993)
Blood.
, vol.82
, pp. 590-599
-
-
Paquette, R.L.1
Landaw, E.M.2
Pierre, R.V.3
-
18
-
-
61849150985
-
High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients
-
Tyner JW, Erickson H, Deininger MW, et al. High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients. Blood. 2009; 113: 1749-1755.
-
(2009)
Blood.
, vol.113
, pp. 1749-1755
-
-
Tyner, J.W.1
Erickson, H.2
Deininger, M.W.3
-
19
-
-
48749108800
-
Deregulation of signaling pathways in acute myeloid leukemia
-
Scholl C, Gilliland DG, Frohling S,. Deregulation of signaling pathways in acute myeloid leukemia. Semin Oncol. 2008; 35: 336-345.
-
(2008)
Semin Oncol.
, vol.35
, pp. 336-345
-
-
Scholl, C.1
Gilliland, D.G.2
Frohling, S.3
-
20
-
-
0037810249
-
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: Potential targeting for therapeutic intervention
-
Chang F, Steelman LS, Lee JT, et al. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. Leukemia. 2003; 17: 1263-1293.
-
(2003)
Leukemia.
, vol.17
, pp. 1263-1293
-
-
Chang, F.1
Steelman, L.S.2
Lee, J.T.3
-
21
-
-
70450195266
-
Implications for KRAS status and EGFR-targeted therapies in metastatic CRC
-
Normanno N, Tejpar S, Morgillo F, De Luca A, Van Cutsem E, Ciardiello F,. Implications for KRAS status and EGFR-targeted therapies in metastatic CRC. Nat Rev Clin Oncol. 2009; 6: 519-527.
-
(2009)
Nat Rev Clin Oncol.
, vol.6
, pp. 519-527
-
-
Normanno, N.1
Tejpar, S.2
Morgillo, F.3
De Luca, A.4
Van Cutsem, E.5
Ciardiello, F.6
-
22
-
-
78149249388
-
Personalized medicine in non-small-cell lung cancer: Is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
-
Roberts PJ, Stinchcombe TE, Der CJ, Socinski MA,. Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy? J Clin Oncol. 2010; 28: 4769-4777.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 4769-4777
-
-
Roberts, P.J.1
Stinchcombe, T.E.2
Der, C.J.3
Socinski, M.A.4
-
23
-
-
70349256226
-
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
-
Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009; 114: 937-951.
-
(2009)
Blood.
, vol.114
, pp. 937-951
-
-
Vardiman, J.W.1
Thiele, J.2
Arber, D.A.3
-
24
-
-
33750456480
-
Reverse phase protein array: Validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
-
Tibes R, Qiu Y, Lu Y, et al. Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol Cancer Ther. 2006; 5: 2512-2521.
-
(2006)
Mol Cancer Ther.
, vol.5
, pp. 2512-2521
-
-
Tibes, R.1
Qiu, Y.2
Lu, Y.3
-
25
-
-
59449102553
-
Functional proteomic profiling of AML predicts response and survival
-
Kornblau SM, Tibes R, Qiu YH, et al. Functional proteomic profiling of AML predicts response and survival. Blood. 2009; 113: 154-164.
-
(2009)
Blood.
, vol.113
, pp. 154-164
-
-
Kornblau, S.M.1
Tibes, R.2
Qiu, Y.H.3
-
26
-
-
3242829141
-
Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining
-
Hunyady B, Krempels K, Harta G, Mezey E,. Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining. J Histochem Cytochem. 1996; 44: 1353-1362.
-
(1996)
J Histochem Cytochem.
, vol.44
, pp. 1353-1362
-
-
Hunyady, B.1
Krempels, K.2
Harta, G.3
Mezey, E.4
-
27
-
-
34548141874
-
Non-parametric quantification of protein lysate arrays
-
Hu J, He X, Baggerly KA, Coombes KR, Hennessy BT, Mills GB,. Non-parametric quantification of protein lysate arrays. Bioinformatics. 2007; 23: 1986-1994.
-
(2007)
Bioinformatics.
, vol.23
, pp. 1986-1994
-
-
Hu, J.1
He, X.2
Baggerly, K.A.3
Coombes, K.R.4
Hennessy, B.T.5
Mills, G.B.6
-
28
-
-
65649083714
-
Variable slope normalization of reverse phase protein arrays
-
Neeley ES, Kornblau SM, Coombes KR, Baggerly KA,. Variable slope normalization of reverse phase protein arrays. Bioinformatics. 2009; 25: 1384-1389.
-
(2009)
Bioinformatics.
, vol.25
, pp. 1384-1389
-
-
Neeley, E.S.1
Kornblau, S.M.2
Coombes, K.R.3
Baggerly, K.A.4
-
29
-
-
1542753559
-
Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
-
International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia International Working Group for Diagnosis
-
Cheson BD, Bennett JM, Kopecky KJ, et al. International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia,. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J Clin Oncol. 2003; 21: 4642-4649.
-
(2003)
J Clin Oncol.
, vol.21
, pp. 4642-4649
-
-
Cheson, B.D.1
Bennett, J.M.2
Kopecky, K.J.3
-
30
-
-
3142717007
-
FLT-3 aberrations in acute promyelocytic leukaemia: Clinicopathological associations and prognostic impact
-
Au WY, Fung A, Chim CS, et al. FLT-3 aberrations in acute promyelocytic leukaemia: clinicopathological associations and prognostic impact. Br J Haematol. 2004; 125: 463-469.
-
(2004)
Br J Haematol.
, vol.125
, pp. 463-469
-
-
Au, W.Y.1
Fung, A.2
Chim, C.S.3
-
31
-
-
12244282411
-
Incidence and prognostic value of FLT3 internal tandem duplication and D835 mutations in acute myeloid leukemia
-
Moreno I, Martin G, Bolufer P, et al. Incidence and prognostic value of FLT3 internal tandem duplication and D835 mutations in acute myeloid leukemia. Haematologica. 2003; 88: 19-24.
-
(2003)
Haematologica.
, vol.88
, pp. 19-24
-
-
Moreno, I.1
Martin, G.2
Bolufer, P.3
-
32
-
-
0036850573
-
Alterations of the FLT3 gene in acute promyelocytic leukemia: Association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol
-
Noguera NI, Breccia M, Divona M, et al. Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol. Leukemia. 2002; 16: 2185-2189.
-
(2002)
Leukemia.
, vol.16
, pp. 2185-2189
-
-
Noguera, N.I.1
Breccia, M.2
Divona, M.3
-
33
-
-
0033572310
-
Ras oncogene-induced sensitization to 1-beta-D-arabinofuranosylcytosine
-
Koo HM, McWilliams MJ, Alvord WG, Vande Woude GF,. Ras oncogene-induced sensitization to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1999; 59: 6057-6062.
-
(1999)
Cancer Res.
, vol.59
, pp. 6057-6062
-
-
Koo, H.M.1
McWilliams, M.J.2
Alvord, W.G.3
Vande Woude, G.F.4
-
34
-
-
10544253077
-
Enhanced sensitivity to 1-beta-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes
-
Koo HM, Monks A, Mikheev A, et al. Enhanced sensitivity to 1-beta-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes. Cancer Res. 1996; 56: 5211-5216.
-
(1996)
Cancer Res.
, vol.56
, pp. 5211-5216
-
-
Koo, H.M.1
Monks, A.2
Mikheev, A.3
|