Fasudil, a Rho-kinase inhibitor, attenuates lipopolysaccharide-induced vascular hyperpermeability and colonic muscle relaxation in guinea pigs

Journal of Surgical Research

Volumn 178, Issue 1, 2012, Pages 352-357

  Suzuki, Kensuke ^a   Nemoto, Kayo ^a,b   Ninomiya, Norifumi ^a   Kuno, Masamune ^a   Kubota, Minoru ^a   Yokota, Hiroyuki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b Shinjuku Vocational College of Acupuncture and Judo Therapy   (Japan)

Author keywords

Endotoxin; Evans Blue; Extravasation; Guinea pig skin; Intracutaneous injection; Rho A

Indexed keywords

EVANS BLUE; FASUDIL; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; COLON; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENDOTOXEMIA; ESCHERICHIA COLI; MALE; MUSCLE RELAXATION; MUSCLE TONE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; CAPILLARY PERMEABILITY; COLON; COLORING AGENTS; DRUG INTERACTIONS; ENDOTOXEMIA; GUINEA PIGS; LIPOPOLYSACCHARIDES; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SKIN;

EID: 84868201488     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.01.043     Document Type: Article

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