ROCK induced inflammation of the microcirculation during endotoxemia mediated by nitric oxide synthase

Microvascular Research

Volumn 81, Issue 3, 2011, Pages 281-288

  McGown, Caroline C ^a   Brown, Nicola J ^a   Hellewell, Paul G ^a   Brookes, Zoë L S ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Fasudil; Lipopolysaccharide; Microvascular inflammation; Nitric oxide; Rho kinase, ROCK

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FASUDIL; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; RHO KINASE; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME INHIBITION; ENZYME REGULATION; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; INTRAVITAL MICROSCOPY; LEUKOCYTE ADHERENCE; MACROMOLECULE; MALE; MESENTERY; MICROSCOPY; MICROVASCULAR INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEPSIS; SIGNAL TRANSDUCTION; VASCULITIS;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; BLOOD PRESSURE; CAPILLARY PERMEABILITY; CELL ADHESION; ENDOTHELIAL CELLS; ENDOTOXEMIA; INFLAMMATION; LEUKOCYTES; LIPOPOLYSACCHARIDES; MALE; MICROCIRCULATION; MICROVESSELS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN KINASE INHIBITORS; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; SPLANCHNIC CIRCULATION;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 79954576279     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2011.02.003     Document Type: Article

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