Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis

Critical Care Medicine

Volumn 40, Issue 11, 2012, Pages 3034-3041

  David, Sascha ^a,b   Mukherjee, Aditi ^a,b   Ghosh, Chandra C ^a,b   Yano, Midori ^a,b   Khankin, Eliyahu V ^a,b   Wenger, Julia B ^c   Ananth Karumanchi, S ^a,b,d   Shapiro, Nathan I ^a,b   Parikh, Samir M ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

angiopoietin 2; endothelium; multiple organ dysfunction; sepsis; tie 2; vasculature

Indexed keywords

ANGIOPOIETIN 2; MONOCLONAL ANTIBODY; VASCULAR ENDOTHELIAL CADHERIN;

ADULT; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DEATH; DISEASE SEVERITY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; EXPERIMENTAL MODEL; FEMALE; HETEROZYGOTE; HOSPITALIZATION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; KIDNEY INJURY; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; MEDIATOR RELEASE; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; OUTCOME ASSESSMENT; PATIENT CARE; PERMEABILITY BARRIER; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEPSIS; SEPTIC SHOCK; SURVIVAL; SURVIVOR; VASCULITIS; WILD TYPE;

ADULT; AGED; AGED, 80 AND OVER; ANGIOPOIETIN-2; ANIMALS; FEMALE; HETEROZYGOTE; HUMANS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MIDDLE AGED; MULTIPLE ORGAN FAILURE; SEPSIS; SURVIVAL ANALYSIS;

EID: 84868196659     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31825fdc31     Document Type: Article

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