Environmental control of the calicheamicin polyketide synthase leads to detection of a programmed octaketide and a proposal for enediyne biosynthesis

Angewandte Chemie - International Edition

Volumn 51, Issue 45, 2012, Pages 11316-11319

  Belecki, Katherine ^a   Townsend, Craig A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

biosynthesis; enediynes; fermentation products; natural products; polyketides

Indexed keywords

CALICHEAMICIN; ENEDIYNES; ENVIRONMENTAL CONTROL; FERMENTATION PRODUCTS; NATURAL PRODUCTS; POLYKETIDE SYNTHASES; POLYKETIDES; THIOESTERASES;

BIOSYNTHESIS; ENVIRONMENTAL MANAGEMENT; FERMENTATION;

BIOCHEMISTRY;

ENEDIYNE; POLYKETIDE; POLYKETIDE SYNTHASE;

ARTICLE; BIOSYNTHESIS; ESCHERICHIA COLI; GENETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ENEDIYNES; ESCHERICHIA COLI; POLYKETIDE SYNTHASES; POLYKETIDES; PROTEIN STRUCTURE, TERTIARY;

EID: 84868159992     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201206462     Document Type: Article

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