Cells on Patterns

Generating Micro- and Nanopatterns on Polymeric Materials

Volumn , Issue , 2011, Pages 267-290

  Ferrari, Aldo ^a   Cecchini, Marco ^b  

^a ETH ZURICH   (Switzerland)

^b INFM   (Italy)

Author keywords

Biomimetic scaffolds; Block copolymer micelle nanolithography; Cells on patterns; Cellular adhesion; Micropatterns nanopatterns; Polymeric materials

Indexed keywords

EID: 84868149248     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527633449.ch12     Document Type: Chapter

References (81)

1. Dalby, M.J. (2009) Nanostructured surfaces: cell engineering and cell biology. Nanomed., 4, 247-248.
2. Fink, J., Thery, M., Azioune, A., Dupont, R., Chatelain, F., Bornens, M. et al. (2007) Comparative study and improvement of current cell micropatterning techniques. Lab on a chip, 7, 672-680.
3. Balaban, N.Q., Schwarz, U.S., Riveline, D., Goichberg, P., Tzur, G., Sabanay, I. et al. (2001) Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat. Cell Biol., 3, 466-472.
4. Katsumi, A., Orr, A.W., Tzima, E., and Schwartz, M.A. (2004) Integrins in mechanotransduction. J. Biol. Chem., 279, 12001-12004.
5. Geiger, B., Bershadsky, A., Pankov, R., and Yamada, K.M. (2001) Transmembrane extracellular matrix-cytoskeleton crosstalk. Nat. Rev. Mol. Cell Biol., 2, 793-805.
6. Zaidel-Bar, R. (2009) Evolution of complexity in the integrin adhesome. J. Cell Biol., 186, 317-321.
7. Zaidel-Bar, R., Itzkovitz, S., Ma'ayan, A., Iyengar, R., and Geiger, B. (2007) Functional atlas of the integrin adhesome. Nat. Cell Biol., 9, 858-867.
8. Wozniak, M.A., Modzelewska, K., Kwong, L., and Keely, P.J. (2004) Focal adhesion regulation of cell behavior. Biochim. Biophys. Acta, 1692, 103-119.
9. Geiger, B., Spatz, J.P., and Bershadsky, A.D. (2009) Environmental sensing through focal adhesions. Nat. Rev. Mol. Cell Biol., 10, 21-33.
10. Decuzzi, P. and Ferrari, M. (2009) Modulating cellular adhesion through nanotopography. Biomaterials, 31 (1), 173-179
11. Xu, R., Boudreau, A., and Bissell, M.J. (2009) Tissue architecture and function: dynamic reciprocity via extra-and intracellular matrices. Cancer Metastasis Rev., 28, 167-176.
12. Chen, C.S., Mrksich, M., Huang, S., Whitesides, G.M., and Ingber, D.E. (1997) Geometric control of cell life and death. Science, 276, 1425-1428.
13. Massia, S.P. and Hubbell, J.A. (1990) Covalently attached GRGD on polymer surfaces promotes biospecific adhesion of mammalian cells. Ann. N. Y. Acad. Sci., 589, 261-270.
14. Glass, R., Moller, M., and Spatz, J.P. (2003) Block copolymer micelle nanolithography. Nanotechnology., 14, 1153-1160.
15. Arnold, M., Schwieder, M., Blummel, J., Cavalcanti-Adam, E.A., Lopez-Garcia, M., Kessler, H. et al. (2009) Cell interactions with hierarchically structured nanopatterned adhesive surfaces. Soft Matter, 5 (1), 72-77.
16. Aydin, D., Schwieder, M., Louban, I., Knoppe, S., Ulmer, J., Haas, T.L. et al. (2009) Micro-nanostructured protein arrays: a tool for geometrically controlled ligand presentation. Small, 5, 1014-1018.
17. Cavalcanti-Adam, E.A., Micoulet, A., Blummel, J., Auernheimer, J., Kessler, H., and Spatz, J.P. (2006) Lateral spacing of integrin ligands influences cell spreading and focal adhesion assembly. Eur. J. Cell Biol., 85, 219-224.
18. Cavalcanti-Adam, E.A., Volberg, T., Micoulet, A., Kessler, H., Geiger, B., and Spatz, J.P. (2007) Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. Biophys. J., 92, 2964-2974.
19. Selhuber-Unkel, C., Lopez-Garcia, M., Kessler, H., and Spatz, J.P. (2008) Cooperativity in adhesion cluster formation during initial cell adhesion. Biophys. J., 95, 5424-5431.
20. Arnold, M., Hirschfeld-Warneken, V.C., Lohmuller, T., Heil, P., Blummel, J., Cavalcanti-Adam, E.A. et al. (2008) Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing. Nano Lett., 8, 2063-2069.
21. Ranzinger, J., Krippner-Heidenreich, A., Haraszti, T., Bock, E., Tepperink, J., Spatz, J.P. et al. (2009) Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation. Nano Lett., 9 (12), 4240-4245.
22. Zaidel-Bar, R., Cohen, M., Addadi, L., and Geiger, B. (2004)Hierarchical assembly of cell-matrix adhesion complexes. Biochem. Soc. Trans., 32, 416-420.
23. Mossman, K.D., Campi, G., Groves, J.T., and Dustin, M.L. (2005) Altered TCR signaling from geometrically repatterned immunological synapses. Science, 310, 1191-1193.
24. Arnold, M., Schwieder, M., Blummel, J., Cavalcanti-Adam, E.A., Lopez-Garcia, M., Kessler, H. et al. (2009) Cell interactions with hierarchically structured nano-patterned adhesive surfaces. Soft Matter, 5, 72-77.
25. Jaehrling, S., Thelen, K., Wolfram, T., and Pollerberg, G.E. (2009) Nanopatterns biofunctionalized with cell adhesion molecule DM-GRASP offered as cell substrate: spacing determines attachment and differentiation of neurons. Nano Lett., 9 (12), 4115-4121.
26. Curtis, A.S. and Varde, M. (1964) Control of cell behavior: topological factors. J. Natl. Cancer Inst., 33, 15-26.
27. Martinez, E., Engel, E., Planell, J.A., and Samitier, J. (2009) Effects of artificial micro-and nano-structured surfaces on cell behaviour. Ann. Anat., 191, 126-135.
28. Shin, H. (2007) Fabrication methods of an engineered microenvironment for analysis of cell-biomaterial interactions. Biomaterials, 28, 126-133.
29. Cecchini, M.,Bumma, G., Serresi, M., and Beltram, F. (2007) PC12 differentiation on biopolymer nanostructures. Nanotechnology, 18, 1-7.
30. Cecchini, M., Ferrari, A., and Beltram, F. (2008) PC12 polarity on biopolymer nanogratings. J. Phys.: Conf. Ser., 100, 012003.
31. Liliensiek, S.J., Wood, J.A., Yong, J., Auerbach, R., Nealey, P.F., and Murphy, C. J. (2010) Modulation of human vascular endothelial cell behaviors by nanotopographic cues. Biomaterials, 31 (20), 5418-26.
32. Ferrari, A., Cecchini, M., Serresi, M., Faraci, P., Pisignano, D., and Beltram, F. (2010) Neuronal polarity selection by topography-induced focal-adhesion control. Biomaterials, 31 (17), 4682-4694.
33. Ferrari, A., Faraci, P., Cecchini, M., and Beltram, F. (2010) The effect of alternative neuronal differentiation pathways on PC12 cell adhesion and neurite alignment to nanogratings. Biomaterials, 31 (17), 2565-2573.
34. Biela, S.A., Su, Y., Spatz, J.P., and Kemkemer, R. (2009) Different sensitivity of human endothelial cells, smooth muscle cells and fibroblasts to topography in the nano-micro range. Acta Biomater., 5 (7), 2460-2466.
35. Dalby, M.J. (2005) Topographically induced direct cell mechanotransduction. Med. Eng. Phys., 27, 730-742.
36. Johansson, F., Carlberg, P., Danielsen, N., Montelius, L., and Kanje, M. (2006) Axonal outgrowth on nano-imprinted patterns. Biomaterials, 27, 1251-1258.
37. Rajnicek, A., Britland, S., and McCaig, C. (1997) Contact guidance of CNS neurites on grooved quartz: influence of groove dimensions, neuronal age and cell type. J. Cell Sci., 110 Pt (23), 2905-2913.
38. Teixeira, A.I., Abrams, G.A., Bertics, P.J., Murphy, C.J., and Nealey, P.F. (2003) Epithelial contact guidance on well-defined micro-and nanostructured substrates. J. Cell Sci., 116, 1881-1892.
39. Dalby, M.J., Gadegaard, N., Tare, R., Andar, A., Riehle, M.O., Herzyk, P. et al. (2007) The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nature Mater., 6, 997-1003.
40. Francisco, H., Yellen, B.B., Halverson, D.S., Friedman, G., and Gallo, G. (2007) Regulation of axon guidance and extension by three-dimensional constraints. Biomaterials, 28, 3398-3407.
41. Tzvetkova-Chevolleau, T., Stephanou, A., Fuard, D., Ohayon, J., Schiavone, P., and Tracqui, P. (2008) The motility of normal and cancer cells in response to the combined influence of the substrate rigidity and anisotropic microstructure. Biomaterials, 29, 1541-1551.
42. Liliensiek, S.J., Wood, J.A., Yong, J., Auerbach, R., Nealey, P.F., and Murphy, C. J. (2010) Modulation of human vascular endothelial cell behaviors by nanotopographic cues. Biomaterials, 31 (20), 5418-5426.
43. Kulangara, K. and Leong, K.W. (2009) Substrate topography shapes cell function. Soft Matter, 5, 4072-4076.
44. Loesberg, W.A., te Riet, J., van Delft, F.C.M.J.M., Schon, P., Figdor, C.G., Speller, S. et al. (2007) The threshold at which substrate nanogroove dimensions may influence fibroblast alignment and adhesion. Biomaterials, 28, 3944-3951.
45. Crouch, A.S., Miller, D., Luebke, K.J., and Hu, W. (2009) Correlation of anisotropic cell behaviors with topographic aspect ratio. Biomaterials, 30, 1560-1567.
46. Biggs, M.J., Richards, R.G., Gadegaard, N., Wilkinson, C.D., Oreffo, R.O., and Dalby, M.J. (2009) The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1{thorn} enriched skeletal stem cells. Biomaterials, 30, 5094-5103.
47. Kim, D.H., Han, K., Gupta, K., Kwon, K.W., Suh, K.Y., and Levchenko, A. (2009) Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients. Biomaterials, 30, 5433-5444.
48. Mattila, P.K. and Lappalainen, P. (2008) Filopodia: molecular architecture and cellular functions. Nat. Rev. Mol. Cell Biol., 9, 446-454.
49. Biggs, M.J., Richards, R.G., Wilkinson, C.D., and Dalby, M.J. (2008) Focal adhesion interactions with topographical structures: a novel method for immuno-SEM labelling of focal adhesions in S-phase cells. J Microsc., 231, 28-37.
50. Dalby, M.J., Hart, A., and Yarwood, S.J. (2008) The effect of the RACK1 signalling protein on the regulation of cell adhesion and cell contact guidance on nanometric grooves. Biomaterials, 29, 282-289.
51. Mahoney, M.J., Chen, R.R., Tan, J., and Saltzman, W.M. (2005) The influence of microchannels on neurite growth and architecture. Biomaterials, 26, 771-778.
52. Walboomers, X.F., Croes, H.J., Ginsel, L.A., and Jansen, J.A. (1998) Growth behavior of fibroblasts on microgrooved polystyrene. Biomaterials, 19, 1861-1868.
53. Engler, A.J., Sen, S., Sweeney, H.L., and Discher, D.E. (2006) Matrix elasticity directs stem cell lineage specification.Cell, 126, 677-689.
54. Huang, J.H., Grater, S.V., Corbellinl, F., Rinck, S., Bock, E., Kemkemer, R. et al. (2009) Impact of order and disorder in RGD nanopatterns on cell adhesion. Nano Lett., 9, 1111-1116.
55. Cukierman, E., Pankov, R., Stevens, D.R., and Yamada, K.M. (2001) Taking cellmatrix adhesions to the third dimension. Science, 294, 1708-1712.
56. Rauch, U. (2007) Brain matrix: structure, turnover and necessity. Biochem. Soc. Trans., 35, 656-660.
57. Engler, A.J., Griffin, M.A., Sen, S., Bonnemann, C.G., Sweeney, H.L., and Discher, D.E. (2004) Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J. Cell Biol., 166, 877-887.
58. Garcia, A.J. and Reyes, C.D. (2005) Bioadhesive surfaces to promote osteoblast differentiation and bone formation. J. Dent. Res., 84, 407-413.
59. Jiang, G.,Huang, A.H.,Cai, Y., Tanase, M., and Sheetz, M.P. (2006) Rigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha. Biophys. J., 90, 1804-1809.
60. Riveline, D., Zamir, E., Balaban, N.Q., Schwarz, U.S., Ishizaki, T., Narumiya, S. et al. (2001) Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J. Cell Biol., 153, 1175-1186.
61. Ferrari, A., Veligodskiy, A., Berge, U., Lucas, M.S., and Kroschewski, R. (2008) ROCK-mediated contractility, tight junctions and channels contribute to the conversion of a preapical patch into apical surface during isochoric lumen initiation. J. Cell Sci., 121, 3649-3663.
62. Bershadsky, A.D., Balaban, N.Q., and Geiger, B. (2003) Adhesion-dependent cell mechanosensitivity. Annu. Rev. Cell Dev. Biol., 19, 677-695.
63. Giancotti, F.G. and Ruoslahti, E. (1999) Transduction-Integrin signaling. Science, 285, 1028-1032.
64. Butler, J.P., Tolic-Norrelykke, I.M., Fabry, B., and Fredberg, J.J. (2002) Traction fields, moments, and strain energy that cells exert on their surroundings. Am. J. Physiol. Cell Physiol., 282, C595-605.
65. Aroush, D.R.B., Zaidel-Bar, R., Bershadsky, A.D., and Wagner, H.D. (2008) Temporal evolution of cell focal adhesions: experimental observations and shear stress profiles. Soft Matter, 4, 2410-2417.
66. Raz-Ben Aroush, D. and Wagner, H.D. (2006) Shear-stress profile along a cell focal adhesion. Adv. Mater., 18, 1537-.
67. Paul, R.,Heil, P., Spatz, J.P., and Schwarz, U.S. (2008) Propagation of mechanical stress through the actin cytoskeleton toward focal adhesions: Model and experiment. Biophys. J., 94, 1470-1482.
68. Dembo, M. and Wang, Y.L. (1999) Stresses at the cell-to-substrate interface during locomotion of fibroblasts. Biophys. J., 76, 2307-2316.
69. Saez, A., Ghibaudo, M., Buguin, A., Silberzan, P., and Ladoux, B. (2007) Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates. Proc. Natl. Acad. Sci. USA, 104, 8281-8286.
70. Wozniak, M.A., Desai, R., Solski, P.A., Der, C.J., and Keely, P.J. (2003) ROCKgenerated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. J. Cell Biol., 163, 583-595.
71. Zeng, D., Ferrari, A., Ulmer, J., Veligodskiy, A., Fischer, P., Spatz, J. et al. (2006) Three-dimensional modeling of mechanical forces in the extracellular matrix during epithelial lumen formation. Biophys. J., 90, 4380-4391.
72. Pelham, R.J. Jr. and Wang, Y. (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. USA, 94, 13661-13665.
73. Lo, C.M., Wang, H.B., Dembo, M., and Wang, Y.L. (2000) Cell movement is guided by the rigidity of the substrate. Biophys. J., 79, 144-152.
74. Gray, D.S., Tien, J., and Chen, C.S. (2003) Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus. J. Biomed.Mater. Res. Part A., 66, 605-614.
75. du Roure, O., Saez, A., Buguin, A., Austin, R.H., Chavrier, P., Silberzan, P. et al. (2005) Force mapping in epithelial cell migration. Proc. Natl. Acad. Sci. USA, 102, 2390-2395.
76. Tan, J.L., Tien, J., Pirone, D.M., Gray, D.S., Bhadriraju, K., and Chen, C.S. (2003) Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc. Natl. Acad. Sci. USA, 100, 1484-1489.
77. Roos, W.H., Roth, A., Konle, J., Presting, H., Sackmann, E., and Spatz, J.P. (2003) Freely suspended actin cortex models on arrays of microfabricated pillars. Chemphyschem, 4, 872-877.
78. Roth, A., Roos, W., Spatz, J., and Sackmann, E. (2003) Elastic properties of freely suspended two-dimesional model actin cortex on microfabricated threedimensional pillar substrates. Biophys. J., 84, 439a-440a.
79. Engelmayr, G.C., Cheng, M.Y., Bettinger, C.J., Borenstein, J.T., Langer, R., and Freed, L.E. (2008) Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nature Mater., 7, 1003-1010.
80. Roach, P., Eglin, D., Rohde, K., and Perry, C.C. (2007) Modern biomaterials: a review-bulk properties and implications of surface modifications. J.Mater. Sci.-Mater. M., 18, 1263-1277.
81. Sun, J.G., Graeter, S.V., Yu, L., Duan, S.F., Spatz, J.P., and Ding, J.D. (2008) Technique of surface modification of a cell-adhesion-resistant hydrogel by a cell-adhesion-available inorganic microarray. Biomacromolecules, 9, 2569-2572.