Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients

Biomaterials

Volumn 30, Issue 29, 2009, Pages 5433-5444

  Kim, Deok Ho ^a   Han, Karam ^a   Gupta, Kshitiz ^a   Kwon, Keon W ^b   Suh, Kahp Yang ^b   Levchenko, Andre ^a  

^a Johns Hopkins University   (United States)

^b Seoul National University   (South Korea)

Author keywords

Cell migration; Extracellular matrix; Focal adhesions; Topography; Wound healing

Indexed keywords

ACTIN CYTOSKELETON; ADHESIVE CELLS; BIPHASIC; CAPILLARY FORCE LITHOGRAPHY; CELL BEHAVIORS; CELL MATRIX INTERACTIONS; CELL MIGRATION; CELL SHAPES; CELLULAR RESPONSE; CYTOSKELETONS; EXPERIMENTAL PLATFORM; EXTRACELLULAR MATRIX; FIBROBLAST CELLS; FOCAL ADHESIONS; GROOVE WIDTH; LIVE-CELL IMAGING; LOCAL DENSITY; LOCAL VARIATIONS; LONG TERM; MATERIAL INTERFACES; MECHANOSENSITIVITY; PATTERN DENSITY; PATTERN ORIENTATION; SHORT TERM; SINGLE CELLS; STRUCTURED DESIGN; ULTRA-VIOLET; WOUND HEALING; WOUND HEALING PROCESS;

ADHESION; ANISOTROPY; BIOMECHANICS; CELL ADHESION; CELL CULTURE; FIBROBLASTS; MOLECULAR DYNAMICS; MONOLAYERS; PRESSURE EFFECTS; TISSUE; TOPOGRAPHY;

CELL MEMBRANES;

ACTIN FILAMENT; ANALYTIC METHOD; ANIMAL CELL; ANISOTROPY; ARTICLE; CAPILLARY FORCE LITHOGRAPHY; CELL ADHESION; CELL DENSITY; CELL FUNCTION; CELL INTERACTION; CELL MIGRATION; CELL SHAPE; CELL STRAIN 3T3; CELL STRUCTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FOCAL ADHESION; IMMUNOCYTOCHEMISTRY; MECHANOTRANSDUCTION; MOLECULAR DYNAMICS; MONOLAYER CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE ENGINEERING; ULTRAVIOLET RADIATION; WOUND HEALING;

ANIMALS; ANISOTROPY; BIOCOMPATIBLE MATERIALS; CELL ADHESION; CELL MOVEMENT; CELL SIZE; FIBROBLASTS; MATERIALS TESTING; MECHANOTRANSDUCTION, CELLULAR; MICE; NIH 3T3 CELLS; SURFACE PROPERTIES;

EID: 68549133138     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.06.042     Document Type: Article

References (46)

1. Kim D.H., Wong P.K., Park J., Levchenko A., and Sun Y. Microengineered platforms for cell mechanobiology. Annu Rev Biomed Eng 11 (2009) 203-233
2. Dalby M.J., Gadegaard N., Tare R., Andar A., Riehle M.O., Herzyk P., et al. The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater 6 12 (2007) 997-1003
3. Patel S., Kurpinski K., Quigley R., Gao H., Hsiao B.S., Poo M.M., et al. Bioactive nanofibers: synergistic effects of nanotopography and chemical signaling on cell guidance. Nano Lett 7 7 (2007) 2122-2128
4. Kim D.H., Levchenko A., and Suh K.Y. Engineered surface nanotopography for controlling cell-substrate interactions. In: Khademhosseini A., Takayama S., and Toner M. (Eds). Micro- and nanoengineering of the cell microenvironment: technologies and applications (2008), Artech House, Boston 185-208
5. Ottani V., Raspanti M., and Ruggeri A. Collagen structure and functional implications. Micron 32 3 (2001) 251-260
6. Kim D.H., Seo C.H., Han K., Kwon K.W., Levchenko A., and Suh K.Y. Guided cell migration on microtextured substrates with variable local density and anisotropy. Adv Funct Mater 19 (2009) 1579-1586
7. Silver F.H., DeVore D., and Siperko L.M. Invited review: role of mechanophysiology in aging of ECM: effects of changes in mechanochemical transduction. J Appl Physiol 95 5 (2003) 2134-2141
8. Chung J.H., and Eun H.C. Angiogenesis in skin aging and photoaging. J Dermatol 34 9 (2007) 593-600
9. Fisher G.J., Wang Z.Q., Datta S.C., Varani J., Kang S., and Voorhees J.J. Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 337 20 (1997) 1419-1428
10. Teixeira A.I., Abrams G.A., Bertics P.J., Murphy C.J., and Nealey P.F. Epithelial contact guidance on well-defined micro- and nanostructured substrates. J Cell Sci 116 10 (2003) 1881-1892
11. Crouch A.S., Miller D., Luebke K.J., and Hu W. Correlation of anisotropic cell behaviors with topographic aspect ratio. Biomaterials 30 8 (2009) 1560-1567
12. Huang N.F., Patel S., Thakar R.G., Wu J., Hsiao B.S., Chu B., et al. Myotube assembly on nanofibrous and micropatterned polymers. Nano Lett 6 3 (2006) 537-542
13. Karuri N.W., Porri T.J., Albrecht R.M., Murphy C.J., and Nealey P.F. Nano- and microscale holes modulate cell-substrate adhesion, cytoskeletal organization, and -beta1 integrin localization in SV40 human corneal epithelial cells. IEEE Trans Nanobioscience 5 4 (2006) 273-280
14. Karuri N.W., Liliensiek S., Teixeira A.I., Abrams G., Campbell S., Nealey P.F., et al. Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells. J Cell Sci 117 15 (2004) 3153-3164
15. Diehl K.A., Foley J.D., Nealey P.F., and Murphy C.J. Nanoscale topography modulates corneal epithelial cell migration. J Biomed Mater Res A 75 3 (2005) 603-611
16. Kaiser J.P., Reinmann A., and Bruinink A. The effect of topographic characteristics on cell migration velocity. Biomaterials 27 30 (2006) 5230-5241
17. Liliensiek S.J., Campbell S., Nealey P.F., and Murphy C.J. The scale of substratum topographic features modulates proliferation of corneal epithelial cells and corneal fibroblasts. J Biomed Mater Res A 79 1 (2006) 185-192
18. Christopherson G.T., Song H., and Mao H.-Q. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials 30 4 (2009) 556-564
19. Dang J.M., and Leong K.W. Myogenic induction of aligned mesenchymal stem cell sheets by culture on thermally responsive electrospun nanofibers. Adv Mater 19 19 (2007) 2775-2779
20. Yim E.K., Pang S.W., and Leong K.W. Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res 313 9 (2007) 1820-1829
21. Oh S., Brammer K.S., Li Y.S., Teng D., Engler A.J., Chien S., et al. Stem cell fate dictated solely by altered nanotube dimension. Proc Natl Acad Sci U S A 106 7 (2009) 2130-2135
22. Teixeira A., Abrams G., Murphy C., and Nealey P. Cell behavior on lithographically defined nanostructured substrates. J Vac Sci Technol B 21 2 (2003) 683-687
23. Kunzler T.P., Huwiler C., Drobek T., Voros J., and Spencer N.D. Systematic study of osteoblast response to nanotopography by means of nanoparticle-density gradients. Biomaterials 28 33 (2007) 5000-5006
24. Simon K.A., Burton E.A., Han Y., Li J., Huang A., and Luk Y.Y. Enhancing cell adhesion and confinement by gradient nanotopography. J Am Chem Soc 129 16 (2007) 4892-4893
25. Kim D.H., Kim P., Song I., Cha J.M., Lee S.H., Kim B., et al. Guided three-dimensional growth of functional cardiomyocytes on polyethylene glycol nanostructures. Langmuir 22 12 (2006) 5419-5426
26. Kim P., Kim D., Kim B., Choi S., Lee S., Khademhosseini A., et al. Fabrication of nanostructures of polyethylene glycol for applications to protein adsorption and cell adhesion. Nanotechnology 16 10 (2005) 2420-2426
27. Cohen D.M., Chen H., Johnson R.P., Choudhury B., and Craig S.W. Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin. J Biol Chem 280 17 (2005) 17109-17117
28. Kim D.H., Park J., Suh K.Y., Kim P., Choi S.K., Ryu S., et al. Fabrication of patterned micromuscles with high activity for powering biohybrid microdevices. Sens Actuators B 117 2 (2006) 391-400
29. Charest J.L., Eliason M.T., Garcia A.J., and King W.P. Combined microscale mechanical topography and chemical patterns on polymer cell culture substrates. Biomaterials 27 11 (2006) 2487-2494
30. Dalby M.J., Riehle M.O., Sutherland D.S., Agheli H., and Curtis A.S. Use of nanotopography to study mechanotransduction in fibroblasts - methods and perspectives. Eur J Cell Biol 83 4 (2004) 159-169
31. Wood M.A. Colloidal lithography and current fabrication techniques producing in-plane nanotopography for biological applications. J R Soc Interface 4 12 (2007) 1-17
32. Dalby M.J., McCloy D., Robertson M., Wilkinson C.D., and Oreffo R.O. Osteoprogenitor response to defined topographies with nanoscale depths. Biomaterials 27 8 (2006) 1306-1315
33. Dalby M.J., Riehle M.O., Johnstone H.J., Affrossman S., and Curtis A.S. Polymer-demixed nanotopography: control of fibroblast spreading and proliferation. Tissue Eng 8 6 (2002) 1099-1108
34. Yim E.K., Reano R.M., Pang S.W., Yee A.F., Chen C.S., and Leong K.W. Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials 26 26 (2005) 5405-5413
35. Palecek S., Loftus J., Ginsberg M., Lauffenburger D., and Horwitz A. Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature 385 6616 (1997) 537-540
36. Gupton S., and Waterman-Storer C. Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. Cell 125 7 (2006) 1361-1374
37. Yim E.K., and Leong K.W. Significance of synthetic nanostructures in dictating cellular response. Nanomedicine 1 1 (2005) 10-21
38. Curtis A. Tutorial on the biology of nanotopography. IEEE Trans Nanobioscience 3 4 (2004) 293-295
39. Geiger B., and Bershadsky A. Assembly and mechanosensory function of focal contacts. Curr Opin Cell Biol 13 5 (2001) 584-592
40. Oakley C., and Brunette D.M. The sequence of alignment of microtubules, focal contacts and actin filaments in fibroblasts spreading on smooth and grooved titanium substrata. J Cell Sci 106 (1993) 343-354
41. Teixeira A.I., Nealey P.F., and Murphy C.J. Responses of human keratocytes to micro- and nanostructured substrates. J Biomed Mater Res A 71 3 (2004) 369-376
42. Friedl P., Hegerfeldt Y., and Tusch M. Collective cell migration in morphogenesis and cancer. Int J Dev Biol 48 5-6 (2004) 441-449
43. Liang C.C., Park A.Y., and Guan J.L. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2 2 (2007) 329-333
44. Goffin J.M., Pittet P., Csucs G., Lussi J.W., Meister J.J., and Hinz B. Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers. J Cell Biol 172 2 (2006) 259-268
45. Sniadecki N.J., Anguelouch A., Yang M.T., Lamb C.M., Liu Z., Kirschner S.B., et al. Magnetic microposts as an approach to apply forces to living cells. Proc Natl Acad Sci U S A 104 37 (2007) 14553-14558
46. Manwaring M.E., Walsh J.F., and Tresco P.A. Contact guidance induced organization of extracellular matrix. Biomaterials 25 17 (2004) 3631-3638