Effect of hydrocarbon stapling on the properties of α-helical antimicrobial peptides isolated from the venom of hymenoptera

Amino Acids

Volumn 43, Issue 5, 2012, Pages 2047-2058

  Chapuis, Hubert ^a   Slaninová, Jiřina ^a   Bednárová, Lucie ^a   Monincová, Lenka ^a   Buděšínský, Miloš ^a   Čeřovský, Václav ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Amphipathic helix; Analogs; Antimicrobial peptides; CD spectroscopy; Stapled peptides

Indexed keywords

2 (4' PENTENYL)ALANINE; 2 (7' OCTENYL)ALANINE; ALANINE DERIVATIVE; ALKENE; BEE VENOM; HYDROCARBON; LASIOGLOSSIN III DERIVATIVE; MELECTIN DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; TETRACYCLINE; UNCLASSIFIED DRUG; WATER;

ALPHA HELIX; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CANDIDA ALBICANS; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; ERYTHROCYTE; ESCHERICHIA COLI; HEMOLYSIS; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MICROCOCCUS LUTEUS; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; RING CLOSING METATHESIS; STAPHYLOCOCCUS AUREUS;

ALKENES; AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; BEE VENOMS; BEES; CANDIDA ALBICANS; CHROMATOGRAPHY, REVERSE-PHASE; CIRCULAR DICHROISM; ERYTHROCYTES; HEMOLYSIS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PROTEOLYSIS;

APOIDEA; HYMENOPTERA;

EID: 84868131345     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-012-1283-1     Document Type: Article

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