-
1
-
-
36549005949
-
Host defence peptides-a bridge between the innate and adaptive immune responses
-
DOI 10.1016/j.trstmh.2007.07.005, PII S0035920307002349
-
Allaker, R. P. (2008). Host defence peptides - a bridge between the innate and adaptive immune responses. Trans R Soc Trop Med Hyg 102, 3-4. (Pubitemid 350177424)
-
(2008)
Transactions of the Royal Society of Tropical Medicine and Hygiene
, vol.102
, Issue.1
, pp. 3-4
-
-
Allaker, R.P.1
-
2
-
-
0028034160
-
How the pharmaceutical industry brings an antibiotic drug to market in the United States
-
Billstein, S. A. (1994). How the pharmaceutical industry brings an antibiotic drug to market in the United States. Antimicrob Agents Chemother 38, 2679-2682. (Pubitemid 24374420)
-
(1994)
Antimicrobial Agents and Chemotherapy
, vol.38
, Issue.12
, pp. 2679-2682
-
-
Billstein, S.A.1
-
3
-
-
16844381376
-
Impact of LL-37 on anti-infective immunity
-
Bowdish, D. M. E., Davidson, D. J., Lau, Y. E., Lee, K., Scott, M. G. & Hancock, R. E. W. (2005). Impact of LL-37 on anti-infective immunity. J Leukoc Biol 77, 451-459.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 451-459
-
-
Bowdish, D.M.E.1
Davidson, D.J.2
Lau, Y.E.3
Lee, K.4
Scott, M.G.5
Hancock, R.E.W.6
-
4
-
-
14544282377
-
Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
-
Brogden, K. A. (2005). Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 3, 238-250.
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 238-250
-
-
Brogden, K.A.1
-
5
-
-
34547561306
-
Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease
-
DOI 10.1110/ps.072933007
-
Cheng, L., Naumann, T. A., Horswill, A. R., Hong, S. J., Venters, B. J., Tomsho, J. W., Benkovic, S. J. & Keiler, K. C. (2007). Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease. Protein Sci 16, 1535-1542. (Pubitemid 47195681)
-
(2007)
Protein Science
, vol.16
, Issue.8
, pp. 1535-1542
-
-
Cheng, L.1
Naumann, T.A.2
Horswill, A.R.3
Hong, S.-J.4
Venters, B.J.5
Tomsho, J.W.6
Benkovic, S.J.7
Keiler, K.C.8
-
6
-
-
27144511502
-
Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity
-
DOI 10.1182/blood-2005-02-0530
-
Cho, J. H., Fraser, I. P., Fukase, K., Kusumoto, S., Fujimoto, Y., Stahl, G. L. & Ezekowitz, R. A. B. (2005). Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity. Blood 106, 2551-2558. (Pubitemid 41510833)
-
(2005)
Blood
, vol.106
, Issue.7
, pp. 2551-2558
-
-
Ju, H.C.1
Fraser, I.P.2
Fukase, K.3
Kusumoto, S.4
Fujimoto, Y.5
Stahl, G.L.6
Ezekowitz, R.A.B.7
-
7
-
-
0029876415
-
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2
-
DOI 10.1038/380548a0
-
Colas, P., Cohen, B., Jessen, T., Grishina, I., Mccoy, J. & Brent, R. (1996). Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2. Nature 380, 548-550. (Pubitemid 26110646)
-
(1996)
Nature
, vol.380
, Issue.6574
, pp. 548-550
-
-
Colas, P.1
Cohen, B.2
Jessen, T.3
Grishina, I.4
McCoy, J.5
Brent, R.6
-
8
-
-
23044472138
-
Systemic antibacterial activity of novel synthetic cyclic peptides
-
DOI 10.1128/AAC.49.8.3302-3310.2005
-
Dartois, V., Sanchez-Quesada, J., Cabezas, E., Chi, E., Dubbelde, C., Dunn, C., Granja, J., Gritzen, C., Weinberger, D. & other authors (2005). Systemic antibacterial activity of novel synthetic cyclic peptides. Antimicrob Agents Chemother 49, 3302-3310. (Pubitemid 41060575)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.8
, pp. 3302-3310
-
-
Dartois, V.1
Sanchez-Quesada, J.2
Cabezas, E.3
Chi, E.4
Dubbelde, C.5
Dunn, C.6
Granja, J.7
Gritzen, C.8
Weinberger, D.9
Ghadiri, M.R.10
Parr Jr., T.R.11
-
9
-
-
18844446685
-
Emerging anti-HIV drugs
-
De Clercq, E. (2005). Emerging anti-HIV drugs. Expert Opin Emerg Drugs 10, 241-273.
-
(2005)
Expert Opin Emerg Drugs
, vol.10
, pp. 241-273
-
-
De Clercq, E.1
-
10
-
-
0029310477
-
Characterization of human serum N-acetylmuramyl-L-alanine amidase purified by affinity chromatography
-
Depauw, P., Neyt, C., Vanderwinkel, E., Wattiez, R. & Falmagne, P. (1995). Characterization of human serum N-acetylmuramyl-L-alanine amidase purified by affinity chromatography. Protein Expr Purif 6, 371-378.
-
(1995)
Protein Expr Purif
, vol.6
, pp. 371-378
-
-
Depauw, P.1
Neyt, C.2
Vanderwinkel, E.3
Wattiez, R.4
Falmagne, P.5
-
11
-
-
85025529077
-
A new class of disinfectant
-
Domagk, G. (1935). A new class of disinfectant. Dtsch Med Wochenschr 61, 829-832.
-
(1935)
Dtsch Med Wochenschr
, vol.61
, pp. 829-832
-
-
Domagk, G.1
-
12
-
-
0038826813
-
Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice
-
DOI 10.1182/blood-2002-12-3853
-
Dziarski, R., Platt, K. A., Gelius, E., Steiner, H. & Gupta, D. (2003). Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice. Blood 102, 689-697. (Pubitemid 36841993)
-
(2003)
Blood
, vol.102
, Issue.2
, pp. 689-697
-
-
Dziarski, R.1
Platt, K.A.2
Gelius, E.3
Steiner, H.4
Gupta, D.5
-
14
-
-
33646472926
-
Protection against bubonic and pneumonic plague with a single dose microencapsulated sub-unit vaccine
-
Elvin, S. J., Eyles, J. E., Howard, K. A., Ravichandran, E., Somavarappu, S., Alpar, H. O. & Williamson, E. D. (2006). Protection against bubonic and pneumonic plague with a single dose microencapsulated sub-unit vaccine. Vaccine 24, 4433-4439.
-
(2006)
Vaccine
, vol.24
, pp. 4433-4439
-
-
Elvin, S.J.1
Eyles, J.E.2
Howard, K.A.3
Ravichandran, E.4
Somavarappu, S.5
Alpar, H.O.6
Williamson, E.D.7
-
15
-
-
17844389346
-
Bioactive peptides from libraries
-
Falciani, C., Lozzi, L., Pini, A. & Bracci, L. (2005). Bioactive peptides from libraries. Chem Biol 12, 417-426.
-
(2005)
Chem Biol
, vol.12
, pp. 417-426
-
-
Falciani, C.1
Lozzi, L.2
Pini, A.3
Bracci, L.4
-
16
-
-
0035954729
-
Antibacterial agents based on the cyclic D,L-alpha-peptide architecture
-
DOI 10.1038/35086601
-
Fernandez-Lopez, S., Kim, H. S., Choi, E. C., Delgado, M., Granja, J. R., Khasanov, A., Kraehenbuehl, K., Long, G., Weinberger, D. A. & other authors (2001). Antibacterial agents based on the cyclic D,Lalpha-peptide architecture. Nature 412, 452-455. (Pubitemid 32702711)
-
(2001)
Nature
, vol.412
, Issue.6845
, pp. 452-455
-
-
Fernandez-Lopez, S.1
Kim, H.-S.2
Choi, E.C.3
Delgado, M.4
Granja, J.R.5
Khasanov, A.6
Kraehenbuehl, K.7
Long, G.8
Weinberger, D.A.9
Wilcoxen, K.M.10
Ghadiri, M.R.11
-
17
-
-
0036127006
-
Mucosal or parenteral administration of microsphere-associated Bacillus anthracis protective antigen protects against anthrax infection in mice
-
DOI 10.1128/IAI.70.4.2022-2028.2002
-
Flick-Smith, H. C., Eyles, J. E., Hebdon, R., Waters, E. L., Beedham, R. J., Stagg, T. J., Miller, J., Alpar, H. O., Baillie, L. W. J. & Williamson, E. D. (2002). Mucosal or parenteral administration of microsphereassociated Bacillus anthracis protective antigen protects against anthrax infection in mice. Infect Immun 70, 2022-2028. (Pubitemid 34242204)
-
(2002)
Infection and Immunity
, vol.70
, Issue.4
, pp. 2022-2028
-
-
Flick-Smith, H.C.1
Eyles, J.E.2
Hebdon, R.3
Waters, E.L.4
Beedham, R.J.5
Stagg, T.J.6
Miller, J.7
Alpar, H.O.8
Baillie, L.W.J.9
Williamson, E.D.10
-
18
-
-
34247875630
-
The cyclophilin inhibitor DEBIO-025 has a potent dual anti-HIV and anti-HCV activity in treatment-naive HIV/HCV co-infected subjects
-
Flisiak, R., Horban, A., Kierkus, J., Stanczak, J., Cielnak, I., Stanczak, G. P., Wiercinska-Drapalo, A., Siwak, E., Higersberger, J. & other authors (2006). The cyclophilin inhibitor DEBIO-025 has a potent dual anti-HIV and anti-HCV activity in treatment-naive HIV/HCV co-infected subjects. Hepatology 44, 1130.
-
(2006)
Hepatology
, vol.44
, pp. 1130
-
-
Flisiak, R.1
Horban, A.2
Kierkus, J.3
Stanczak, J.4
Cielnak, I.5
Stanczak, G.P.6
Wiercinska-Drapalo, A.7
Siwak, E.8
Higersberger, J.9
-
19
-
-
40949117600
-
The cyclophilin inhibitor debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus
-
Flisiak, R., Horban, A., Gallay, P., Bobardt, M., Selvarajah, S., Wiercinska-Drapalo, A., Siwak, E., Cielniak, I., Higersberger, J. & other authors (2008). The cyclophilin inhibitor debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus. Hepatology 47, 817-826.
-
(2008)
Hepatology
, vol.47
, pp. 817-826
-
-
Flisiak, R.1
Horban, A.2
Gallay, P.3
Bobardt, M.4
Selvarajah, S.5
Wiercinska-Drapalo, A.6
Siwak, E.7
Cielniak, I.8
Higersberger, J.9
-
20
-
-
60849123435
-
Smart polymers for controlled delivery of proteins and peptides
-
a review of patents
-
Fogueri, L. R. & Singh, S. (2009). Smart polymers for controlled delivery of proteins and peptides: a review of patents. Recent Pat Drug Deliv Formul 3, 40-48.
-
(2009)
Recent Pat Drug Deliv Formul
, vol.3
, pp. 40-48
-
-
Fogueri, L.R.1
Singh, S.2
-
22
-
-
0037757622
-
A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-L- alanine amidase activity
-
DOI 10.1016/S0006-291X(03)01096-9
-
Gelius, E., Persson, C., Karlsson, J. & Steiner, H. (2003). A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-L-alanine amidase activity. Biochem Biophys Res Commun 306, 988-994. (Pubitemid 36776228)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.306
, Issue.4
, pp. 988-994
-
-
Gelius, E.1
Persson, C.2
Karlsson, J.3
Steiner, H.4
-
23
-
-
33947393032
-
Antimicrobial peptides: An overview of a promising class of therapeutics
-
DOI 10.2478/s11535-007-0010-5
-
Giuliani, A., Pirri, G. & Nicoletto, S. F. (2007). Antimicrobial peptides: an overview of a promising class of therapeutics. Cent Eur J Biol 2, 1-33. (Pubitemid 46450753)
-
(2007)
Central European Journal of Biology
, vol.2
, Issue.1
, pp. 1-33
-
-
Giuliani, A.1
Pirri, G.2
Nicoletto, S.F.3
-
24
-
-
0030905981
-
New insights into the mechanisms and importance of the proteasome in intracellular protein degradation
-
Goldberg, A. L., Akopian, T. N., Kisselev, A. F., Lee, D. H. & Rohrwild,M. (1997). New insights into the mechanisms and importance of the proteasome in intracellular protein degradation. Biol Chem 378, 131-140. (Pubitemid 27230595)
-
(1997)
Biological Chemistry
, vol.378
, Issue.3-4
, pp. 131-140
-
-
Goldberg, A.L.1
Akopian, T.N.2
Kisselev, A.F.3
Lee, D.H.4
Rohrwild, M.5
-
25
-
-
0030949875
-
Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
-
DOI 10.1016/S0092-8674(00)81895-4
-
Goldman, M. J., Anderson, G. M., Stolzenberg, E. D., Kari, U. P., Zasloff, M. & Wilson, J. M. (1997). Human beta-defensin-1 is a saltsensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 88, 553-560. (Pubitemid 27154420)
-
(1997)
Cell
, vol.88
, Issue.4
, pp. 553-560
-
-
Goldman, M.J.1
Anderson, G.M.2
Stolzenberg, E.D.3
Kari, U.P.4
Zasloff, M.5
Wilson, J.M.6
-
26
-
-
20044385757
-
Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway
-
Grace, M. J., Lee, S., Bradshaw, S., Chapman, J., Spond, J., Cox, S., DeLorenzo, M., Brassard, D., Wylie, D. & other authors (2005). Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway. J Biol Chem 280, 6327-6336.
-
(2005)
J Biol Chem
, vol.280
, pp. 6327-6336
-
-
Grace, M.J.1
Lee, S.2
Bradshaw, S.3
Chapman, J.4
Spond, J.5
Cox, S.6
Delorenzo, M.7
Brassard, D.8
Wylie, D.9
-
27
-
-
3843067734
-
Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
-
DOI 10.1074/jbc.M404920200
-
Guan, R., Malchiodi, E. L., Wang, Q., Schuck, P. & Mariuzza, R. A. (2004a). Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein I alpha. J Biol Chem 279, 31873-31882. (Pubitemid 39037860)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31873-31882
-
-
Guan, R.1
Malchiodi, E.L.2
Wang, Q.3
Schuck, P.4
Mariuzza, R.A.5
-
28
-
-
10344259137
-
Structural basis for peptidoglycan binding by peptidoglycan recognition proteins
-
DOI 10.1073/pnas.0407856101
-
Guan, R., Roychowdhury, A., Ember, B., Kumar, S., Boons, G.-J. & Mariuzza, R. A. (2004b). Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc Natl Acad Sci U S A 101, 17168-17173. (Pubitemid 39627792)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.49
, pp. 17168-17173
-
-
Guan, R.1
Roychowdhury, A.2
Ember, B.3
Kumar, S.4
Boons, G.-J.5
Mariuzza, R.A.6
-
29
-
-
14844353929
-
Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 angstrom resolution
-
DOI 10.1016/j.jmb.2005.01.070
-
Guan, R., Wang, Q., Sundberg, E. J. & Mariuzza, R. A. (2005). Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 angstrom resolution. J Mol Biol 347, 683-691. (Pubitemid 40357912)
-
(2005)
Journal of Molecular Biology
, vol.347
, Issue.4
, pp. 683-691
-
-
Guan, R.1
Wang, Q.2
Sundberg, E.J.3
Mariuzza, R.A.4
-
30
-
-
33646140122
-
Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria
-
Guan, R., Brown, P. H., Swaminathan, C. P., Roychowdhury, A., Boons, G.-J. & Mariuzza, R. A. (2006). Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria. Protein Sci 15, 1199-1206.
-
(2006)
Protein Sci
, vol.15
, pp. 1199-1206
-
-
Guan, R.1
Brown, P.H.2
Swaminathan, C.P.3
Roychowdhury, A.4
Boons, G.-J.5
Mariuzza, R.A.6
-
31
-
-
0033912828
-
A novel artificial loop scaffold for the noncovalent constraint of peptides
-
DOI 10.1016/S1074-5521(00)00137-X
-
Gururaja, T. L., Narasimhamurthy, S., Payan, D. G. & Anderson, D. C. (2000). A novel artificial loop scaffold for the noncovalent constraint of peptides. Chem Biol 7, 515-527. (Pubitemid 30466986)
-
(2000)
Chemistry and Biology
, vol.7
, Issue.7
, pp. 515-527
-
-
Gururaja, T.L.1
Narasimhamurthy, S.2
Payan, D.G.3
Anderson, D.4
-
32
-
-
0021185399
-
Alterations in outer-membrane permeability
-
Hancock, R. E. W. (1984). Alterations in outer-membrane permeability. Annu Rev Microbiol 38, 237-264.
-
(1984)
Annu Rev Microbiol
, vol.38
, pp. 237-264
-
-
Hancock, R.E.W.1
-
33
-
-
0035496012
-
Cationic peptides: Effectors in innate immunity and novel antimicrobials
-
DOI 10.1016/S1473-3099(01)00092-5, PII S1473309901000925
-
Hancock, R. E. W. (2001). Cationic peptides: effectors in innate immunity and novel antimicrobials. Lancet Infect Dis 1, 156-164. (Pubitemid 33586049)
-
(2001)
Lancet Infectious Diseases
, vol.1
, Issue.3
, pp. 156-164
-
-
Hancock, R.E.1
-
34
-
-
0028306217
-
Somatostatin and somatostatin analogues: Pharmacokinetics and pharmacodynamic effects
-
Harris, A. G. (1994). Somatostatin and somatostatin analogs - pharmacokinetics and pharmacodynamic effects. Gut 35, S1-S4. (Pubitemid 24157987)
-
(1994)
Gut
, vol.35
, Issue.SUPPL. 3
-
-
Harris, A.G.1
-
35
-
-
0037362655
-
Effect of pegylation on pharmaceuticals
-
Harris, J. M. & Chess, R. B. (2003). Effect of pegylation on pharmaceuticals. Nat Rev Drug Discov 2, 214-221.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
36
-
-
10644265116
-
Cyclophilin interactions with incoming human immunodeficiency virus type 1 capsids with opposing effects on infectivity in human cells
-
DOI 10.1128/JVI.79.1.176-183.2005
-
Hatziioannou, T., Perez-Caballero, D., Cowan, S. & Bieniasz, P. D. (2005). Cyclophilin interactions with incoming human immunodeficiency virus type 1 capsids with opposing effects on infectivity in human cells. J Virol 79, 176-183. (Pubitemid 39648375)
-
(2005)
Journal of Virology
, vol.79
, Issue.1
, pp. 176-183
-
-
Hatziioannou, T.1
Perez-Caballero, D.2
Cowan, S.3
Bieniasz, P.D.4
-
37
-
-
0033580768
-
Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed PEGylation
-
DOI 10.1016/S0024-3205(99)00257-X, PII S002432059900257X
-
He, X. H., Shaw, P. C. & Tam, S. C. (1999). Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed PEGylation. Life Sci 65, 355-368. (Pubitemid 29325279)
-
(1999)
Life Sciences
, vol.65
, Issue.4
, pp. 355-368
-
-
He, X.-H.1
Shaw, P.-C.2
Tam, S.-C.3
-
38
-
-
0033532378
-
An essential role for DNA adenine methylation in bacterial virulence
-
DOI 10.1126/science.284.5416.967
-
Heithoff, D. M., Sinsheimer, R. L., Low, D. A. & Mahan, M. J. (1999). An essential role for DNA adenine methylation in bacterial virulence. Science 284, 967-970. (Pubitemid 29288436)
-
(1999)
Science
, vol.284
, Issue.5416
, pp. 967-970
-
-
Heithoff, D.M.1
Sinsheimer, R.L.2
Low, D.A.3
Mahan, M.J.4
-
39
-
-
36249000683
-
Viral kinetics during 14-day treatment with debio-025 demonstrate efficient blocking of viral replication in different HCV genotypes without signs of emerging viral resistance
-
Herrmann, E., Flisiak, R., Horban, A., Crabbe, R., Porchet, H., Nicolas, V., Scalfaro, P. & Zeuzem, S. (2007). Viral kinetics during 14-day treatment with debio-025 demonstrate efficient blocking of viral replication in different HCV genotypes without signs of emerging viral resistance. J Hepatol 46, 88.
-
(2007)
J Hepatol
, vol.46
, pp. 88
-
-
Herrmann, E.1
Flisiak, R.2
Horban, A.3
Crabbe, R.4
Porchet, H.5
Nicolas, V.6
Scalfaro, P.7
Zeuzem, S.8
-
40
-
-
0029867623
-
Proteasomes: Destruction as a programme
-
Hilt, W. & Wolf, D. H. (1996). Proteasomes: destruction as a programme. Trends Biochem Sci 21, 96-102.
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 96-102
-
-
Hilt, W.1
Wolf, D.H.2
-
41
-
-
0344418718
-
Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide
-
DOI 10.1016/S0006-2952(99)00259-2, PII S0006295299002592
-
Hong, S. Y., Oh, J. E. & Lee, K. H. (1999). Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide. Biochem Pharmacol 58, 1775-1780. (Pubitemid 29505418)
-
(1999)
Biochemical Pharmacology
, vol.58
, Issue.11
, pp. 1775-1780
-
-
Hong, S.Y.1
Oh, J.E.2
Lee, K.-H.3
-
42
-
-
8144225538
-
A systematic method for identifying small-molecule modulators of protein-protein interactions
-
DOI 10.1073/pnas.0406999101
-
Horswill, A. R., Savinov, S. N. & Benkovic, S. J. (2004). A systematic method for identifying small-molecule modulators of protein-protein interactions. Proc Natl Acad Sci U S A 101, 15591-15596. (Pubitemid 39473532)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.44
, pp. 15591-15596
-
-
Horswill, A.R.1
Savinov, S.N.2
Benkovic, S.J.3
-
43
-
-
41149108458
-
A comparative view at comprehensive information resources on three-dimensional structures of biological macro-molecules
-
DOI 10.1093/bfgp/elm020, Special Issue: Resources for Functional Genomics and Proteomics
-
Hühne, R., Koch, F.-T. & Sühnel, J. (2007). A comparative view at comprehensive information resources on three-dimensional structures of biological macro-molecules. Brief Funct Genomics Proteomics 6, 220-239. (Pubitemid 351863878)
-
(2007)
Briefings in Functional Genomics and Proteomics
, vol.6
, Issue.3
, pp. 220-239
-
-
Hu1
hne, R.2
Koch, F.-T.3
Suhnel, J.4
-
44
-
-
47349122368
-
Mannose-targeted systems for the delivery of therapeutics
-
Irache, J. M., Salman, H. H., Gamazo, C. & Espuelas, S. (2008). Mannose-targeted systems for the delivery of therapeutics. Expert Opin Drug Deliv 5, 703-724.
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 703-724
-
-
Irache, J.M.1
Salman, H.H.2
Gamazo, C.3
Espuelas, S.4
-
45
-
-
33746086672
-
How good is your screening library?
-
Irwin, J. J. (2006). How good is your screening library? Curr Opin Chem Biol 10, 352-356.
-
(2006)
Curr Opin Chem Biol
, vol.10
, pp. 352-356
-
-
Irwin, J.J.1
-
46
-
-
52949117666
-
Peptide-polymer biotherapeutic synthesis on novel cross-linked beads with "Spatially Tunable" and "Isolated" functional sites
-
Jacob, M. K., Leena, S. & Kumar, K. S. (2008). Peptide-polymer biotherapeutic synthesis on novel cross-linked beads with "Spatially Tunable" and "Isolated" functional sites. Biopolymers 90, 512-525.
-
(2008)
Biopolymers
, vol.90
, pp. 512-525
-
-
Jacob, M.K.1
Leena, S.2
Kumar, K.S.3
-
47
-
-
33746532309
-
Peptide antimicrobial agents
-
Jenssen, H., Hamill, P. & Hancock, R. E. W. (2006). Peptide antimicrobial agents. Clin Microbiol Rev 19, 491-511.
-
(2006)
Clin Microbiol Rev
, vol.19
, pp. 491-511
-
-
Jenssen, H.1
Hamill, P.2
Hancock, R.E.W.3
-
48
-
-
40749110680
-
N-terminal acetylation protects glucagon-like peptide GLP-1-(7-34)-amide from DPP-IV-mediated degradation retaining cAMPand insulin-releasing capacity
-
John, H., Maronde, E., Forssmann, W. G., Meyer, M. & Adermann, K. (2008). N-terminal acetylation protects glucagon-like peptide GLP-1-(7-34)-amide from DPP-IV-mediated degradation retaining cAMPand insulin-releasing capacity. Eur J Med Res 13, 73-78.
-
(2008)
Eur J Med Res
, vol.13
, pp. 73-78
-
-
John, H.1
Maronde, E.2
Forssmann, W.G.3
Meyer, M.4
Adermann, K.5
-
49
-
-
0035179775
-
DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae
-
DOI 10.1128/IAI.69.12.7610-7615.2001
-
Julio, S. M., Heithoff, D. M., Provenzano, D., Klose, K. E., Sinsheimer, R. L., Low, D. A. & Mahan, M. J. (2001). DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae. Infect Immun 69, 7610-7615. (Pubitemid 33086589)
-
(2001)
Infection and Immunity
, vol.69
, Issue.12
, pp. 7610-7615
-
-
Julio, S.M.1
Heithoff, D.M.2
Provenzano, D.3
Klose, K.E.4
Sinsheimer, R.L.5
Low, D.A.6
Mahan, M.J.7
-
50
-
-
0032544089
-
A peptidoglycan recognition protein in innate immunity conserved from insects to humans
-
DOI 10.1073/pnas.95.17.10078
-
Kang, D., Liu, G., Lundstrom, A., Gelius, E. & Steiner, H. (1998). A peptidoglycan recognition protein in innate immunity conserved from insects to humans. Proc Natl Acad Sci U S A 95, 10078-10082. (Pubitemid 28415297)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.17
, pp. 10078-10082
-
-
Kang, D.1
Liu, G.2
Lundstrom, A.3
Gelius, E.4
Steiner, H.5
-
51
-
-
0030024281
-
Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
-
Keiler, K. C., Waller, P. R. H. & Sauer, R. T. (1996). Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA. Science 271, 990-993. (Pubitemid 26066397)
-
(1996)
Science
, vol.271
, Issue.5251
, pp. 990-993
-
-
Keiler, K.C.1
Waller, P.R.H.2
Sauer, R.T.3
-
52
-
-
3242666740
-
Pharmacokinetic and pharmacodynamic characteristics of a long-acting Growth Hormone (GH) preparation (nutropin depot) in GH-deficient children
-
DOI 10.1210/jc.2003-030825
-
Kemp, S. F., Fielder, P. J., Attie, K. M., Blethen, S. L., Reiter, E. O., Ford, K. M., Marian, M., Dao, L. N., Lee, H. J. & Saenger, P. (2004). Pharmacokinetic and pharmacodynamic characteristics of a longacting growth hormone (GH) preparation (nutropin depot) in GHdeficient children. J Clin Endocrinol Metab 89, 3234-3240. (Pubitemid 38951887)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.7
, pp. 3234-3240
-
-
Kemp, S.F.1
Fielder, P.J.2
Attie, K.M.3
Blethen, S.L.4
Reiter, E.O.5
Ford, K.M.6
Marian, M.7
Dao, L.N.8
Lee, H.J.9
Saenger, P.10
-
53
-
-
0033791440
-
Pharmacokinetic study of niosome encapsulated insulin
-
Khaksa, G., D'Souza, R., Lewis, S. & Udupa, N. (2000). Pharmacokinetic study of niosome encapsulated insulin. Indian J Exp Biol 38, 901-905. (Pubitemid 30784853)
-
(2000)
Indian Journal of Experimental Biology
, vol.38
, Issue.9
, pp. 901-905
-
-
Khaksa, G.1
D'Souza, R.2
Lewis, S.3
Udupa, N.4
-
54
-
-
27744522261
-
Selective recognition of synthetic lysine and meso-diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition proteins 1 alpha and S
-
DOI 10.1074/jbc.M506385200
-
Kumar, S., Roychowdhury, A., Ember, B., Wang, Q., Guan, R. J., Mariuzza, R. A. & Boons, G. J. (2005). Selective recognition of synthetic lysine and meso-diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition proteins I alpha and S. J Biol Chem 280, 37005-37012. (Pubitemid 41587784)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 37005-37012
-
-
Kumar, S.1
Roychowdhury, A.2
Ember, B.3
Wang, Q.4
Guan, R.5
Mariuzza, R.A.6
Boons, G.-J.7
-
55
-
-
0034730496
-
A specificity-enhancing factor for the clpXP degradation machine
-
DOI 10.1126/science.289.5488.2354
-
Levchenko, I., Seidel, M., Sauer, R. T. & Baker, T. A. (2000). A specificity-enhancing factor for the ClpXP degradation machine. Science 289, 2354-2356. (Pubitemid 30739740)
-
(2000)
Science
, vol.289
, Issue.5488
, pp. 2354-2356
-
-
Levchenko, I.1
Seidel, M.2
Sauer, R.T.3
Baker, T.A.4
-
56
-
-
51649131501
-
The synthetic antimicrobial peptide KLKL5KLK enhances the protection and efficacy of the combined DNA vaccine against Mycobacterium tuberculosis
-
Li, M., Yu, D. H. & Cai, H. (2008). The synthetic antimicrobial peptide KLKL5KLK enhances the protection and efficacy of the combined DNA vaccine against Mycobacterium tuberculosis. DNA Cell Biol 27, 405-413.
-
(2008)
DNA Cell Biol
, vol.27
, pp. 405-413
-
-
Li, M.1
Yu, D.H.2
Cai, H.3
-
57
-
-
0035860732
-
Peptidoglycan recognition proteins: A novel family of four human innate immunity pattern recognition molecules
-
DOI 10.1074/jbc.M105566200
-
Liu, C., Xu, Z. J., Gupta, D. & Dziarski, R. (2001). Peptidoglycan recognition proteins - a novel family of four human innate immunity pattern recognition molecules. J Biol Chem 276, 34686-34694. (Pubitemid 37384465)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.37
, pp. 34686-34694
-
-
Liu, C.1
Xu, Z.2
Gupta, D.3
Dziarski, R.4
-
58
-
-
58949097012
-
Capsule polysaccharide is a bacterial decoy for antimicrobial peptides
-
Llobet, E., Tomas, J. M. & Bengoechea, J. A. (2008). Capsule polysaccharide is a bacterial decoy for antimicrobial peptides. Microbiology 154, 3877-3886.
-
(2008)
Microbiology
, vol.154
, pp. 3877-3886
-
-
Llobet, E.1
Tomas, J.M.2
Bengoechea, J.A.3
-
59
-
-
33646850266
-
Peptidoglycan recognition proteins are a new class of human bactericidal proteins
-
DOI 10.1074/jbc.M511631200
-
Lu, X., Wang, M. H., Qi, J., Wang, H. T., Li, X. N., Gupta, D. & Dziarski, R. (2006). Peptidoglycan recognition proteins are a new class of human bactericidal proteins. J Biol Chem 281, 5895-5907. (Pubitemid 43847690)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.9
, pp. 5895-5907
-
-
Lu, X.1
Wang, M.2
Qi, J.3
Wang, H.4
Li, X.5
Gupta, D.6
Dziarski, R.7
-
60
-
-
0027207885
-
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins a and B
-
DOI 10.1016/0092-8674(93)90637-6
-
Luban, J., Bossolt, K. L., Franke, E. K., Kalpana, G. V. & Goff, S. P. (1993). Human-immunodeficiency-virus type-1 Gag protein binds to cyclophilin-A and cyclophilin-B. Cell 73, 1067-1078. (Pubitemid 23180482)
-
(1993)
Cell
, vol.73
, Issue.6
, pp. 1067-1078
-
-
Luban, J.1
Bossolt, K.L.2
Franke, E.K.3
Kalpana, G.V.4
Goff, S.P.5
-
61
-
-
33748413776
-
Antibacterial peptides for therapeutic use: Obstacles and realistic outlook
-
DOI 10.1016/j.coph.2006.04.006, PII S1471489206001299, Anti-infectives/New Technologies
-
Marr, A. K., Gooderham, W. J. & Hancock, R. E. W. (2006). Antibacterial peptides for therapeutic use: obstacles and realistic outlook. Curr Opin Pharmacol 6, 468-472. (Pubitemid 44340665)
-
(2006)
Current Opinion in Pharmacology
, vol.6
, Issue.5
, pp. 468-472
-
-
Marr, A.K.1
Gooderham, W.J.2
Hancock, R.E.3
-
62
-
-
33645811489
-
Screening and determination of gene function using randomized ribozyme and siRNA libraries
-
Matsumoto, S., Akashi, H. & Taira, K. (2006). Screening and determination of gene function using randomized ribozyme and siRNA libraries. Handb Exp Pharmacol 173, 197-221.
-
(2006)
Handb Exp Pharmacol
, vol.173
, pp. 197-221
-
-
Matsumoto, S.1
Akashi, H.2
Taira, K.3
-
63
-
-
0037470091
-
A scavenger function for a Drosophila peptidoglycan recognition protein
-
DOI 10.1074/jbc.M208900200
-
Mellroth, P., Karlsson, J. & Steiner, H. (2003). A scavenger function for a Drosophila peptidoglycan recognition protein. J Biol Chem 278, 7059-7064. (Pubitemid 36800702)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.9
, pp. 7059-7064
-
-
Mellroth, P.1
Karlsson, J.2
Steiner, H.3
-
64
-
-
26944431987
-
Ribosome rescue: TmRNA tagging activity and capacity in Escherichia coli
-
DOI 10.1111/j.1365-2958.2005.04832.x
-
Moore, S. D. & Sauer, R. T. (2005). Ribosome rescue: tmRNA tagging activity and capacity in Escherichia coli. Mol Microbiol 58, 456-466. (Pubitemid 41476161)
-
(2005)
Molecular Microbiology
, vol.58
, Issue.2
, pp. 456-466
-
-
Moore, S.D.1
Sauer, R.T.2
-
65
-
-
38849125577
-
Genetic selection of cyclic peptide dam methyltransferase inhibitors
-
DOI 10.1002/cbic.200700561
-
Naumann, T. A., Tavassoli, A. & Benkovic, S. J. (2008). Genetic selection of cyclic peptide dam methyltransferase inhibitors. ChemBioChem 9, 194-197. (Pubitemid 351196784)
-
(2008)
ChemBioChem
, vol.9
, Issue.2
, pp. 194-197
-
-
Naumann, T.A.1
Tavassoli, A.2
Benkovic, S.J.3
-
66
-
-
0032969563
-
+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
-
Neuwald, A. F., Aravind, L., Spouge, J. L. & Koonin, E. V. (1999). AAA(+): a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 9, 27-43. (Pubitemid 29095146)
-
(1999)
Genome Research
, vol.9
, Issue.1
, pp. 27-43
-
-
Neuwald, A.F.1
Aravind, L.2
Spouge, J.L.3
Koonin, E.V.4
-
67
-
-
0027356555
-
Methylation of DNA in prokaryotes
-
Noyer-Weidner, M. & Trautner, T. A. (1993). Methylation of DNA in prokaryotes. EXS 64, 39-108.
-
(1993)
EXS
, vol.64
, pp. 39-108
-
-
Noyer-Weidner, M.1
Trautner, T.A.2
-
68
-
-
1542297763
-
CIS display: In vitro selection of peptides from libraries of protein-DNA complexes
-
DOI 10.1073/pnas.0400219101
-
Odegrip, R., Coomber, D., Eldridge, B., Hederer, R., Kuhlman, P. A., Ullman, C., FitzGerald, K. & McGregor, D. (2004). CIS display: in vitro selection of peptides from libraries of protein-DNA complexes. Proc Natl Acad Sci U S A 101, 2806-2810. (Pubitemid 38327692)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.9
, pp. 2806-2810
-
-
Odegrip, R.1
Coomber, D.2
Eldridge, B.3
Hederer, R.4
Kuhlman, P.A.5
Ullman, C.6
Fitzgerald, K.7
McGregor, D.8
-
69
-
-
0034705132
-
Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: Effect on structure, interaction with model membranes, and biological function
-
DOI 10.1021/bi992408i
-
Oren, Z. & Shai, Y. (2000). Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: effect on structure, interaction with model membranes, and biological function. Biochemistry 39, 6103-6114. (Pubitemid 30327085)
-
(2000)
Biochemistry
, vol.39
, Issue.20
, pp. 6103-6114
-
-
Oren, Z.1
Shai, Y.2
-
70
-
-
34248395596
-
Activity and stability of human kallikrein-2-specific linear and cyclic peptide inhibitors
-
DOI 10.1002/psc.849
-
Pakkala, M., Hekim, C., Soininen, P., Leinonen, J., Koistinen, H., Weisell, J., Stenman, U. H., Vepsalainen, J. & Narvanen, A. (2007). Activity and stability of human kalikrein-2-specific linear and cyclic peptide inhibitors. J Pept Sci 13, 348-353. (Pubitemid 46730574)
-
(2007)
Journal of Peptide Science
, vol.13
, Issue.5
, pp. 348-353
-
-
Pakkala, M.1
Hekim, C.2
Soininen, P.3
Leinonen, J.4
Koistinen, H.5
Weisell, J.6
Stenman, U.-H.7
Vepsalainen, J.8
Narvanen, A.9
-
71
-
-
0028294407
-
Calcineurin has a very tight-binding pocket for the side chain of residue 4 of cyclosporin
-
DOI 10.1016/S0960-894X(01)80127-X
-
Papageorgiou, C., Borer, X. & French, R. R. (1994). Calcineurin has a very tight-binding pocket for the side-chain of residue-4 of cyclosporine. Bioorg Med Chem Lett 4, 267-272. (Pubitemid 24127119)
-
(1994)
Bioorganic and Medicinal Chemistry Letters
, vol.4
, Issue.2
, pp. 267-272
-
-
Papageorgiou, C.1
Borer, X.2
French, R.R.3
-
72
-
-
42049124062
-
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent
-
Ptak, R. G., Gallay, P. A., Jochmans, D., Halestrap, A. P., Ruegg, U. T., Pallansch, L. A., Bobardt, M. D., de Bethune, M. P., Neyts, J. & other authors (2008). Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent. Antimicrob Agents Chemother 52, 1302-1317.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1302-1317
-
-
Ptak, R.G.1
Gallay, P.A.2
Jochmans, D.3
Halestrap, A.P.4
Ruegg, U.T.5
Pallansch, L.A.6
Bobardt, M.D.7
De Bethune, M.P.8
Neyts, J.9
-
73
-
-
51149094742
-
ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa
-
Qiu, D., Eisinger, V. M., Head, N. E., Pier, G. B. & Yu, H. D. (2008). ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa. Microbiology 154, 2119-2130.
-
(2008)
Microbiology
, vol.154
, pp. 2119-2130
-
-
Qiu, D.1
Eisinger, V.M.2
Head, N.E.3
Pier, G.B.4
Yu, H.D.5
-
74
-
-
23844468875
-
PEGylated interferon-alpha 2b: A branched 40K polyethylene glycol derivative
-
DOI 10.1007/s11095-005-5278-4
-
Ramon, J., Saez, V., Baez, R., Aldana, R. & Hardy, E. (2005). PEGylated interferon-alpha 2b: a branched 40K polyethylene glycol derivative. Pharm Res 22, 1374-1386. (Pubitemid 41176042)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.8
, pp. 1374-1386
-
-
Ramon, J.1
Saez, V.2
Baez, R.3
Aldana, R.4
Hardy, E.5
-
75
-
-
0036083830
-
The IMB Jena Image Library of Biological Macromolecules: 2002 update
-
Reichert, J. & Sühnel, J. (2002). The IMB Jena Image Library of Biological Macromolecules: 2002 update. Nucleic Acids Res 30, 253-254. (Pubitemid 34679557)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.1
, pp. 253-254
-
-
Reichert, J.1
Suhnel, J.2
-
76
-
-
27444433158
-
A dam mutant of Yersinia pestis is attenuated and induces protection against plague
-
DOI 10.1016/j.femsle.2005.09.001, PII S0378109705006117
-
Robinson, V. L., Oyston, P. C. F. & Titball, R. W. (2005). A dam mutant of Yersinia pestis is attenuated and induces protection against plague. FEMS Microbiol Lett 252, 251-256. (Pubitemid 41531651)
-
(2005)
FEMS Microbiology Letters
, vol.252
, Issue.2
, pp. 251-256
-
-
Robinson, V.L.1
Oyston, P.C.F.2
Titball, R.W.3
-
77
-
-
33947374647
-
Peptidoglycan recognition proteins: Pleiotropic sensors and effectors of antimicrobial defences
-
DOI 10.1038/nrmicro1620, PII NRMICRO1620
-
Royet, J. & Dziarski, R. (2007). Peptidoglycan recognition proteins: pleiotropic sensors and effectors of antimicrobial defences. Nat Rev Microbiol 5, 264-277. (Pubitemid 46443603)
-
(2007)
Nature Reviews Microbiology
, vol.5
, Issue.4
, pp. 264-277
-
-
Royet, J.1
Dziarski, R.2
-
78
-
-
35048842305
-
Liposomal drug delivery systems: An update review
-
DOI 10.2174/156720107782151269
-
Samad, A., Sultana, Y. & Aqil, M. (2007). Liposomal drug delivery systems: an update review. Curr Drug Deliv 4, 297-305. (Pubitemid 47554274)
-
(2007)
Current Drug Delivery
, vol.4
, Issue.4
, pp. 297-305
-
-
Samad, A.1
Sultana, Y.2
Aqil, M.3
-
79
-
-
27744548011
-
Gene silencing and overexpression of porcine peptidoglycan recognition protein long isoforms: Involvement in beta-defensin-1 expression
-
DOI 10.1128/IAI.73.11.7133-7141.2005
-
Sang, Y., Ramanathan, B., Ross, C. R. & Blecha, F. (2005). Gene silencing and overexpression of porcine peptidoglycan recognition protein long isoforms: involvement in beta-defensin-1 expression. Infect Immun 73, 7133-7141. (Pubitemid 41587610)
-
(2005)
Infection and Immunity
, vol.73
, Issue.11
, pp. 7133-7141
-
-
Sang, Y.1
Ramanathan, B.2
Ross, C.R.3
Blecha, F.4
-
80
-
-
0033598747
-
Production of cyclic peptides and proteins in vivo
-
Scott, C. P., Abel-Santos, E., Wall, M., Wahnon, D. C. & Benkovic, S. J. (1999). Production of cyclic peptides and proteins in vivo. Proc Natl Acad Sci U S A 96, 13638-13643.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13638-13643
-
-
Scott, C.P.1
Abel-Santos, E.2
Wall, M.3
Wahnon, D.C.4
Benkovic, S.J.5
-
81
-
-
34147147029
-
An anti-infective peptide that selectively modulates the innate immune response
-
DOI 10.1038/nbt1288, PII NBT1288
-
Scott, M. G., Dullaghan, E., Mookherjee, N., Glavas, N., Waldbrook, M., Thompson, A., Wang, A. K., Lee, K., Doria, S. & other authors (2007). An anti-infective peptide that selectively modulates the innate immune response. Nat Biotechnol 25, 465-472. (Pubitemid 46572850)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.4
, pp. 465-472
-
-
Scott, M.G.1
Dullaghan, E.2
Mookherjee, N.3
Glavas, N.4
Waldbrook, M.5
Thompson, A.6
Wang, A.7
Lee, K.8
Doria, S.9
Hamill, P.10
Yu, J.J.11
Li, Y.12
Donini, O.13
Guarna, M.M.14
Finlay, B.B.15
North, J.R.16
Hancock, R.E.W.17
-
82
-
-
1942534972
-
On the formulation of pH-sensitive liposomes with long circulation times
-
DOI 10.1016/j.addr.2003.10.038, PII S0169409X03002795
-
Simoes, S., Moreira, J. N., Fonseca, C., Duzgunes, N. & de Lima, M. C. P. (2004). On the formulation of pH-sensitive long circulation times. Adv Drug Deliv Rev 56, 947-965. (Pubitemid 38520203)
-
(2004)
Advanced Drug Delivery Reviews
, vol.56
, Issue.7
, pp. 947-965
-
-
Simoes, S.1
Nuno Moreira, J.2
Fonseca, C.3
Duzgunes, N.4
Pedroso De Lima, M.C.5
-
83
-
-
8644286696
-
Target cell cyclophilin a modulates human immunodeficiency virus type 1 infectivity
-
DOI 10.1128/JVI.78.23.12800-12808.2004
-
Sokolskaja, E., Sayah, D. M. & Luban, J. (2004). Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity. J Virol 78, 12800-12808. (Pubitemid 39507788)
-
(2004)
Journal of Virology
, vol.78
, Issue.23
, pp. 12800-12808
-
-
Sokolskaja, E.1
Sayah, D.M.2
Luban, J.3
-
84
-
-
0030855146
-
Protegrin-1: A broad-spectrum, rapidly microbicidal peptide with in vivo activity
-
Steinberg, D. A., Hurst, M. A., Fujii, C. A., Kung, A. H. C., Ho, J. F., Cheng, F. C., Loury, D. J. & Fiddes, J. C. (1997). Protegrin-1: a broadspectrum, rapidly microbicidal peptide with in vivo activity. Antimicrob Agents Chemother 41, 1738-1742. (Pubitemid 27339878)
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, Issue.8
, pp. 1738-1742
-
-
Steinberg, D.A.1
Hurst, M.A.2
Fujii, C.A.3
Kung, A.H.C.4
Ho, J.F.5
Cheng, F.-C.6
Loury, D.J.7
Fiddes, J.C.8
-
85
-
-
0019386682
-
Sequence and specificity of two antibacterial proteins involved in insect immunity
-
DOI 10.1038/292246a0
-
Steiner, H., Hultmark, D., Engstrom, A., Bennich, H. & Boman, H. G. (1981). Sequence and specificity of two anti-bacterial proteins involved in insect immunity. Nature 292, 246-248. (Pubitemid 11001840)
-
(1981)
Nature
, vol.292
, Issue.5820
, pp. 246-248
-
-
Steiner, H.1
Hultmark, D.2
Engstrom, A.3
-
86
-
-
0028874049
-
Mode of action of Sdz Nim-811, a nonimmunosuppressive cyclosporine-A analog with activity against human-immunodeficiency-virus type-1 (HIV-1): Interference with early and late events in HIV-1 replication
-
Steinkasserer, A., Harrison, R., Billich, A., Hammerschmid, F., Werner, G., Wolff, B., Peichl, P., Palfi, G., Schnitzel, W. & other authors (1995). Mode of action of Sdz Nim-811, a nonimmunosuppressive cyclosporine-A analog with activity against human-immunodeficiency-virus type-1 (HIV-1): interference with early and late events in HIV-1 replication. J Virol 69, 814-824.
-
(1995)
J Virol
, vol.69
, pp. 814-824
-
-
Steinkasserer, A.1
Harrison, R.2
Billich, A.3
Hammerschmid, F.4
Werner, G.5
Wolff, B.6
Peichl, P.7
Palfi, G.8
Schnitzel, W.9
-
87
-
-
59749089160
-
Evaluation of strategies for improving proteolytic resistance of antimicrobial peptides by using variants of EFK17, an internal segment of LL-37
-
Stromstedt, A. A., Pasupuleti, M., Schmidtchen, A. & Malmsten, M. (2009). Evaluation of strategies for improving proteolytic resistance of antimicrobial peptides by using variants of EFK17, an internal segment of LL-37. Antimicrob Agents Chemother 53, 593-602.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 593-602
-
-
Stromstedt, A.A.1
Pasupuleti, M.2
Schmidtchen, A.3
Malmsten, M.4
-
88
-
-
33644553496
-
Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21
-
DOI 10.1007/s00439-005-0115-8
-
Sun, C., Mathur, P., Dupuis, J., Tizard, R., Ticho, B., Crowell, T., Gardner, H., Bowcock, A. M. & Carulli, J. (2006). Peptidoglycan recognition proteins PGLRP3 and PGLRP4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21. Hum Genet 119, 113-125. (Pubitemid 43300203)
-
(2006)
Human Genetics
, vol.119
, Issue.1-2
, pp. 113-125
-
-
Sun, C.1
Mathur, P.2
Dupuis, J.3
Tizard, R.4
Ticho, B.5
Crowell, T.6
Gardner, H.7
Bowcock, A.M.8
Carulli, J.9
-
89
-
-
31444438761
-
Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs)
-
DOI 10.1073/pnas.0507656103
-
Swaminathan, C. P., Brown, P. H., Roychowdhury, A., Wang, Q., Guan, R. J., Silverman, N., Goldman, W. E., Boons, G. J. & Mariuzza, R. A. (2006). Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc Natl Acad Sci U S A 103, 684-689. (Pubitemid 43153086)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.3
, pp. 684-689
-
-
Swaminathan, C.P.1
Brown, P.H.2
Roychowdhury, A.3
Wang, Q.4
Guan, R.5
Silverman, N.6
Goldman, W.E.7
Boons, G.-J.8
Mariuzza, R.A.9
-
90
-
-
33644839988
-
Diversity-oriented synthesis: Exploring the intersections between chemistry and biology
-
Tan, D. S. (2005). Diversity-oriented synthesis: exploring the intersections between chemistry and biology. Nat Chem Biol 1, 74-84.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 74-84
-
-
Tan, D.S.1
-
91
-
-
34250354508
-
Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli
-
DOI 10.1038/nprot.2007.152, PII NPROT.2007.152
-
Tavassoli, A. & Benkovic, S. J. (2007). Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli. Nat Protoc 2, 1126-1133. (Pubitemid 46908238)
-
(2007)
Nature Protocols
, vol.2
, Issue.5
, pp. 1126-1133
-
-
Tavassoli, A.1
Benkovic, S.J.2
-
92
-
-
21344442880
-
Oral immunization with a dam mutant of Yersinia pseudotuberculosis protects against plague
-
DOI 10.1099/mic.0.27959-0
-
Taylor, V. L., Titball, R. W. & Oyston, P. C. F. (2005). Oral immunization with a Dam mutant of Yersinia pseudotuberculosis protects against plague. Microbiology 151, 1919-1926. (Pubitemid 40909034)
-
(2005)
Microbiology
, vol.151
, Issue.6
, pp. 1919-1926
-
-
Taylor, V.L.1
Titball, R.W.2
Oyston, P.C.F.3
-
93
-
-
41549150296
-
Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides
-
Thongyoo, P., Roque-Rosell, N., Leatherbarrow, R. J. & Tate, E. W. (2008). Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides. Org Biomol Chem 6, 1462-1470.
-
(2008)
Org Biomol Chem
, vol.6
, pp. 1462-1470
-
-
Thongyoo, P.1
Roque-Rosell, N.2
Leatherbarrow, R.J.3
Tate, E.W.4
-
94
-
-
33748283311
-
DNA and RNA aptamers: From tools for basic research towards therapeutic applications
-
DOI 10.2174/138620706778249695
-
Ulrich, H., Trujillo, C. A., Nery, A. A., Alves, J. M., Majumder, P., Resende, R. R. & Martins, A. H. (2006). DNA and RNA aptamers: from tools for basic research towards therapeutic applications. Comb Chem High Throughput Screen 9, 619-632. (Pubitemid 44320411)
-
(2006)
Combinatorial Chemistry and High Throughput Screening
, vol.9
, Issue.8
, pp. 619-632
-
-
Ulrich, H.1
Trujillo, C.A.2
Nery, A.A.3
Alves, J.M.4
Majumder, P.5
Resende, R.R.6
Martins, A.H.7
-
95
-
-
33645527760
-
Protein and small molecule microarrays: Powerful tools for high-throughput proteomics
-
Uttamchandani, M., Wang, J. & Yao, S. Q. (2006). Protein and small molecule microarrays: powerful tools for high-throughput proteomics. Mol Biosyst 2, 58-68.
-
(2006)
Mol Biosyst
, vol.2
, pp. 58-68
-
-
Uttamchandani, M.1
Wang, J.2
Yao, S.Q.3
-
96
-
-
0026802197
-
Agents that increase the permeability of the outer membrane
-
Vaara, M. (1992). Agents that increase the permeability of the outer membrane. Microbiol Rev 56, 395-411.
-
(1992)
Microbiol Rev
, vol.56
, pp. 395-411
-
-
Vaara, M.1
-
97
-
-
56049093057
-
Cell-penetrating and celltargeting peptides in drug delivery
-
Vives, E., Schmidt, J. & Pelegrin, A. (2008). Cell-penetrating and celltargeting peptides in drug delivery. Biochim Biophys Acta 1786, 126-138.
-
(2008)
Biochim Biophys Acta
, vol.1786
, pp. 126-138
-
-
Vives, E.1
Schmidt, J.2
Pelegrin, A.3
-
98
-
-
0346822374
-
Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L- alanine amidase
-
Wang, Z. M., Li, X. N., Cocklin, R. R., Wang, M. H., Wang, M., Fukase, K., Inamura, S., Kusumoto, S., Gupta, D. & Dziarski, R. (2003). Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase. J Biol Chem 278, 49044-49052.
-
(2003)
J Biol Chem
, vol.278
, pp. 49044-49052
-
-
Wang, Z.M.1
Li, X.N.2
Cocklin, R.R.3
Wang, M.H.4
Wang, M.5
Fukase, K.6
Inamura, S.7
Kusumoto, S.8
Gupta, D.9
Dziarski, R.10
-
99
-
-
33847357075
-
Human peptidoglycan recognition proteins require zinc to kill both gram-positive and gram-negative bacteria and are synergistic with antibacterial peptides
-
Wang, M., Liu, L.-H., Wang, S., Li, X., Lu, X., Gupta, D. & Dziarski, R. (2007). Human peptidoglycan recognition proteins require zinc to kill both Gram-positive and Gram-negative bacteria and are synergistic with antibacterial peptides. J Immunol 178, 3116-3125. (Pubitemid 46333193)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 3116-3125
-
-
Wang, M.1
Liu, L.-H.2
Wang, S.3
Li, X.4
Lu, X.5
Gupta, D.6
Dziarski, R.7
-
100
-
-
58149187882
-
APD2: The updated antimicrobial peptide database and its application in peptide design
-
Wang, G., Li, X. & Wang, Z. (2009). APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Res 37, D933-D937.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Wang, G.1
Li, X.2
Wang, Z.3
-
101
-
-
17844364643
-
Current directions in the evolution of compound libraries
-
Webb, T. R. (2005). Current directions in the evolution of compound libraries. Curr Opin Drug Discov Devel 8, 303-308. (Pubitemid 40593424)
-
(2005)
Current Opinion in Drug Discovery and Development
, vol.8
, Issue.3
, pp. 303-308
-
-
Webb, T.R.1
-
102
-
-
0022864077
-
Cyclosporine and analogues: Structural requirements for immunosuppressive activity
-
Wenger, R. (1986). Cyclosporine and analogs - structural requirements for immunosuppressive activity. Transplant Proc 18, 213-218. (Pubitemid 17223797)
-
(1986)
Transplantation Proceedings
, vol.18
, Issue.6 SUPPL. 5
, pp. 213-218
-
-
Wenger, R.1
-
103
-
-
0034610370
-
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
-
Werner, T., Liu, G., Kang, D., Ekengren, S., Steiner, H. & Hultmark, D. (2000). A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster. Proc Natl Acad Sci U S A 97, 13772-13777.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13772-13777
-
-
Werner, T.1
Liu, G.2
Kang, D.3
Ekengren, S.4
Steiner, H.5
Hultmark, D.6
-
104
-
-
0344493788
-
Directed evolution towards protease-resistant hirudin variants
-
DOI 10.1016/j.ymgme.2003.09.007
-
Wirsching, F., Keller, M., Hildmann, C., Riester, D. & Schwienhorst, A. (2003). Directed evolution towards protease-resistant hirudin variants. Mol Genet Metab 80, 451-462. (Pubitemid 37491207)
-
(2003)
Molecular Genetics and Metabolism
, vol.80
, Issue.4
, pp. 451-462
-
-
Wirsching, F.1
Keller, M.2
Hildmann, C.3
Riester, D.4
Schwienhorst, A.5
-
105
-
-
58449107461
-
Chronic pharmacological and safety evaluation of HematideTM, a PEGylated peptidic erythropoiesisstimulating agent, in rodents
-
Woodburn, K. W., Wilson, S. D., Fong, K. L., Schatz, P. J., Spainhour, C. B. & Norton, D. (2009). Chronic pharmacological and safety evaluation of HematideTM, a PEGylated peptidic erythropoiesisstimulating agent, in rodents. Basic Clin Pharmacol Toxicol 104, 155-163.
-
(2009)
Basic Clin Pharmacol Toxicol
, vol.104
, pp. 155-163
-
-
Woodburn, K.W.1
Wilson, S.D.2
Fong, K.L.3
Schatz, P.J.4
Spainhour, C.B.5
Norton, D.6
-
106
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton, N. C., Farrell, F. X., Chang, R., Kashyap, A. K., Barbone, F. P., Mulcahy, L. S., Johnson, D. L., Barrett, R. W., Jolliffe, L. K. & Dower, W. J. (1996). Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273, 458-463. (Pubitemid 26286441)
-
(1996)
Science
, vol.273
, Issue.5274
, pp. 458-463
-
-
Wrighton, N.C.1
Farrell, F.X.2
Chang, R.3
Kashyap, A.K.4
Barbone, F.P.5
Mulcahy, L.S.6
Johnson, D.L.7
Barrett, R.W.8
Jolliffe, L.K.9
Dower, W.J.10
-
107
-
-
0029884417
-
Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori
-
DOI 10.1074/jbc.271.23.13854
-
Yoshida, H., Kinoshita, K. & Ashida, M. (1996). Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori. J Biol Chem 271, 13854-13860. (Pubitemid 26185431)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.23
, pp. 13854-13860
-
-
Yoshida, H.1
Kinoshita, K.2
Ashida, M.3
-
108
-
-
38849134035
-
Human cathelicidin CAP18/LL-37 changes mast cell function toward innate immunity
-
DOI 10.1248/bpb.31.212
-
Yoshioka, M., Fukuishi, N., Ku, Y., Yamanobe, H., Ohsaki, K., Kawasoe, Y., Murata, M., Ishzumi, A., Nishi, Y. & other authors (2008). Human cathelicidin CAP18/LL-37 changes mast cell function toward innate immunity. Biol Pharm Bull 31, 212-216. (Pubitemid 351198391)
-
(2008)
Biological and Pharmaceutical Bulletin
, vol.31
, Issue.2
, pp. 212-216
-
-
Yoshioka, M.1
Fukuishi, N.2
Kubo, Y.3
Yamanobe, H.4
Ohsaki, K.5
Kawasoe, Y.6
Murata, M.7
Ishizumi, A.8
Nishii, Y.9
Matsui, N.10
Akagi, M.11
-
109
-
-
33947418509
-
Multifunctional antimicrobial peptides: Therapeutic targets in several human diseases
-
DOI 10.1007/s00109-006-0143-4
-
Zaiou, M. (2007). Multifunctional antimicrobial peptides: therapeutic targets in several human diseases. J Mol Med 85, 317-329. (Pubitemid 46452258)
-
(2007)
Journal of Molecular Medicine
, vol.85
, Issue.4
, pp. 317-329
-
-
Zaiou, M.1
-
110
-
-
2042513493
-
Magainins, a class of antimicrobial peptides from Xenopus skin: Isolation, characterization of two active forms, and partial cDNA sequence of a precursor
-
Zasloff, M. (1987). Magainins, a class of antimicrobial peptides from Xenopus skin - isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A 84, 5449-5453. (Pubitemid 17129018)
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.15
, pp. 5449-5453
-
-
Zasloff, M.1
-
111
-
-
0027316918
-
Molecular mechanisms of immunosuppression by cyclosporins
-
Zenke, G., Baumann, G., Wenger, R., Hiestand, P., Quesniaux, V., Andersen, E. & Schreier, M. H. (1993). Molecular mechanisms of immunosuppression by cyclosporins. Ann N Y Acad Sci 685, 330-335.
-
(1993)
Ann N Y Acad Sci
, vol.685
, pp. 330-335
-
-
Zenke, G.1
Baumann, G.2
Wenger, R.3
Hiestand, P.4
Quesniaux, V.5
Andersen, E.6
Schreier, M.H.7
-
112
-
-
23944434403
-
Identification of serum N-acetylmuramoyl-L-alanine amidase as liver peptidoglycan recognition protein 2
-
DOI 10.1016/j.bbapap.2005.07.001, PII S1570963905002025
-
Zhang, Y., van der Fits, L., Voerman, J. S., Melief, M.-J., Laman, J. D., Wang, M., Wang, H., Wang, M., Li, X. & other authors (2005). Identification of serum N-acetylmuramoyl-L-alanine amidase as liver peptidoglycan recognition protein 2. Biochim Biophys Acta 1752, 34-46. (Pubitemid 41207248)
-
(2005)
Biochimica et Biophysica Acta - Proteins and Proteomics
, vol.1752
, Issue.1
, pp. 34-46
-
-
Zhang, Y.1
Van Der Fits, L.2
Voerman, J.S.3
Melief, M.-J.4
Laman, J.D.5
Wang, M.6
Wang, H.7
Wang, M.8
Li, X.9
Walls, C.D.10
Gupta, D.11
Dziarski, R.12
|