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Volumn 1, Issue 1, 2012, Pages 33-43

Small RNA and its application in andrology and urology

Author keywords

Andrology; Bladder cancer; Erectile dysfunction; MicroRNA; Prostate cancer; RNAa; RNAi; Small RNA; Urology

Indexed keywords


EID: 84868126740     PISSN: 22234683     EISSN: 22234691     Source Type: Journal    
DOI: 10.3978/j.issn.2223-4683.2011.12.04     Document Type: Review
Times cited : (20)

References (97)
  • 1
    • 0035195942 scopus 로고    scopus 로고
    • Non-coding RNAs: the architects of eukaryotic complexity
    • Mattick JS. Non-coding RNAs: the architects of eukaryotic complexity. EMBO Rep 2001;2:986-91.
    • (2001) EMBO Rep , vol.2 , pp. 986-991
    • Mattick, J.S.1
  • 2
    • 33751251990 scopus 로고    scopus 로고
    • Small dsRNAs induce transcriptional activation in human cells
    • Li LC, Okino ST, Zhao H, et al. Small dsRNAs induce transcriptional activation in human cells. Proc Natl Acad Sci U S A 2006;103:17337-42.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17337-17342
    • Li, L.C.1    Okino, S.T.2    Zhao, H.3
  • 3
    • 33847081733 scopus 로고    scopus 로고
    • Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
    • Janowski BA, Younger ST, Hardy DB, et al. Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat Chem Biol 2007;3:166-73.
    • (2007) Nat Chem Biol , vol.3 , pp. 166-173
    • Janowski, B.A.1    Younger, S.T.2    Hardy, D.B.3
  • 5
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 6
    • 40349094597 scopus 로고    scopus 로고
    • MicroRNA-373 induces expression of genes with complementary promoter sequences
    • Place RF, Li LC, Pookot D, et al. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci U S A 2008;105:1608-13.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 1608-1613
    • Place, R.F.1    Li, L.C.2    Pookot, D.3
  • 7
    • 34547441263 scopus 로고    scopus 로고
    • Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR
    • Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR. Proc Natl Acad Sci U S A 2007;104:9667-72.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9667-9672
    • Lytle, J.R.1    Yario, T.A.2    Steitz, J.A.3
  • 8
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
    • Tay Y, Zhang J, Thomson AM, et al. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008;455:1124-8.
    • (2008) Nature , vol.455 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3
  • 9
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno L, Salmena L, Zhang J, et al. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010;465:1033-8.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3
  • 10
    • 80054700538 scopus 로고    scopus 로고
    • Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
    • Tay Y, Kats L, Salmena L, et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 2011;147:344-57.
    • (2011) Cell , vol.147 , pp. 344-357
    • Tay, Y.1    Kats, L.2    Salmena, L.3
  • 11
    • 77649133970 scopus 로고    scopus 로고
    • miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts
    • Eiring AM, Harb JG, Neviani P, et al. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell 2010;140:652-65.
    • (2010) Cell , vol.140 , pp. 652-665
    • Eiring, A.M.1    Harb, J.G.2    Neviani, P.3
  • 12
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004;101:2999-3004.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 13
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006;103:2257-61.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 14
    • 0033520712 scopus 로고    scopus 로고
    • PTEN gene and integrin signaling in cancer
    • Tamura M, Gu J, Tran H, et al. PTEN gene and integrin signaling in cancer. J Natl Cancer Inst 1999;91:1820-8.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1820-1828
    • Tamura, M.1    Gu, J.2    Tran, H.3
  • 15
    • 39749163245 scopus 로고    scopus 로고
    • Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
    • Xiao C, Srinivasan L, Calado DP, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 2008;9:405-14.
    • (2008) Nat Immunol , vol.9 , pp. 405-414
    • Xiao, C.1    Srinivasan, L.2    Calado, D.P.3
  • 16
    • 33748302836 scopus 로고    scopus 로고
    • Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
    • Dews M, Homayouni A, Yu D, et al. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 2006;38:1060-5.
    • (2006) Nat Genet , vol.38 , pp. 1060-1065
    • Dews, M.1    Homayouni, A.2    Yu, D.3
  • 17
    • 39849095077 scopus 로고    scopus 로고
    • E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer
    • Petrocca F, Visone R, Onelli MR, et al. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008;13:272-86.
    • (2008) Cancer Cell , vol.13 , pp. 272-286
    • Petrocca, F.1    Visone, R.2    Onelli, M.R.3
  • 18
    • 77953948708 scopus 로고    scopus 로고
    • Identification of the miR- 106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
    • Poliseno L, Salmena L, Riccardi L, et al. Identification of the miR- 106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal 2010;3:ra29.
    • (2010) Sci Signal , vol.3
    • Poliseno, L.1    Salmena, L.2    Riccardi, L.3
  • 19
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • Kumar M, Lu Z, Takwi AA, et al. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 2011;30:843-53.
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3
  • 20
    • 52949127316 scopus 로고    scopus 로고
    • MiR-221 controls CDKN1C/ p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
    • Fornari F, Gramantieri L, Ferracin M, et al. MiR-221 controls CDKN1C/ p57 and CDKN1B/p27 expression in human hepatocellular carcinoma. Oncogene 2008;27:5651-61.
    • (2008) Oncogene , vol.27 , pp. 5651-5661
    • Fornari, F.1    Gramantieri, L.2    Ferracin, M.3
  • 21
    • 76249128792 scopus 로고    scopus 로고
    • miR-221 overexpression contributes to liver tumorigenesis
    • Pineau P, Volinia S, McJunkin K, et al. miR-221 overexpression contributes to liver tumorigenesis. Proc Natl Acad Sci U S A 2010;107:264-9.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 264-269
    • Pineau, P.1    Volinia, S.2    McJunkin, K.3
  • 22
    • 70949104622 scopus 로고    scopus 로고
    • miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    • Garofalo M, Di Leva G, Romano G, et al. miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 2009;16:498-509.
    • (2009) Cancer Cell , vol.16 , pp. 498-509
    • Garofalo, M.1    Di Leva, G.2    Romano, G.3
  • 23
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, et al. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008;283:1026-33.
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3
  • 24
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007;133:647-58.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3
  • 25
    • 77952948062 scopus 로고    scopus 로고
    • Overexpression of miR- 21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB
    • Connolly EC, Van Doorslaer K, Rogler LE, et al. Overexpression of miR- 21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB. Mol Cancer Res 2010;8:691-700.
    • (2010) Mol Cancer Res , vol.8 , pp. 691-700
    • Connolly, E.C.1    Van Doorslaer, K.2    Rogler, L.E.3
  • 26
    • 50249173450 scopus 로고    scopus 로고
    • MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
    • Gabriely G, Wurdinger T, Kesari S, et al. MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 2008;28:5369-80.
    • (2008) Mol Cell Biol , vol.28 , pp. 5369-5380
    • Gabriely, G.1    Wurdinger, T.2    Kesari, S.3
  • 27
    • 84860408968 scopus 로고    scopus 로고
    • DNA methylation-associated silencing of tumor suppressor microRNAs in cancer
    • Oncogene 2011 Aug 22. DOI: 10.1038/ onc.2011.354
    • Lopez-Serra P, Esteller M. DNA methylation-associated silencing of tumor suppressor microRNAs in cancer. Oncogene 2011 Aug 22. DOI: 10.1038/ onc.2011.354.
    • Lopez-Serra, P.1    Esteller, M.2
  • 28
    • 25444520537 scopus 로고    scopus 로고
    • miR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A 2005;102:13944-9.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 29
    • 52649088391 scopus 로고    scopus 로고
    • miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
    • Liu Q, Fu H, Sun F, et al. miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res 2008;36:5391-404.
    • (2008) Nucleic Acids Res , vol.36 , pp. 5391-5404
    • Liu, Q.1    Fu, H.2    Sun, F.3
  • 30
    • 55549114664 scopus 로고    scopus 로고
    • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
    • Bonci D, Coppola V, Musumeci M, et al. The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 2008;14:1271-7.
    • (2008) Nat Med , vol.14 , pp. 1271-1277
    • Bonci, D.1    Coppola, V.2    Musumeci, M.3
  • 31
    • 54949154476 scopus 로고    scopus 로고
    • MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
    • Hua Z, Lv Q, Ye W, et al. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One 2006;1:e116.
    • (2006) PLoS One , vol.1
    • Hua, Z.1    Lv, Q.2    Ye, W.3
  • 32
    • 84901200001 scopus 로고    scopus 로고
    • Small RNA-mediated regulation of basic fibroblast growth factor (FGF2) in prostate cancer [abstract]
    • American Association for Cancer Research 100st annual meeting, Denver
    • Wang J, Place R, Li L. Small RNA-mediated regulation of basic fibroblast growth factor (FGF2) in prostate cancer [abstract]. American Association for Cancer Research 100st annual meeting, Denver 2009;s2536.
    • (2009)
    • Wang, J.1    Place, R.2    Li, L.3
  • 33
    • 80054032535 scopus 로고    scopus 로고
    • Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer
    • Musumeci M, Coppola V, Addario A, et al. Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer. Oncogene 2011;30:4231-42.
    • (2011) Oncogene , vol.30 , pp. 4231-4242
    • Musumeci, M.1    Coppola, V.2    Addario, A.3
  • 34
    • 78650204499 scopus 로고    scopus 로고
    • Repression of the miR- 143/145 cluster by oncogenic Ras initiates a tumor-promoting feedforward pathway
    • Kent OA, Chivukula RR, Mullendore M, et al. Repression of the miR- 143/145 cluster by oncogenic Ras initiates a tumor-promoting feedforward pathway. Genes Dev 2010;24:2754-9.
    • (2010) Genes Dev , vol.24 , pp. 2754-2759
    • Kent, O.A.1    Chivukula, R.R.2    Mullendore, M.3
  • 35
    • 62549148270 scopus 로고    scopus 로고
    • p53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva M, Zhu S, Wu F, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci U S A 2009;106:3207- 12.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3
  • 36
    • 73649135801 scopus 로고    scopus 로고
    • Gene networks and microRNAs implicated in aggressive prostate cancer
    • Wang L, Tang H, Thayanithy V, et al. Gene networks and microRNAs implicated in aggressive prostate cancer. Cancer Res 2009;69:9490-7.
    • (2009) Cancer Res , vol.69 , pp. 9490-9497
    • Wang, L.1    Tang, H.2    Thayanithy, V.3
  • 37
    • 77950818716 scopus 로고    scopus 로고
    • MicroRNA145 targets BNIP3 and suppresses prostate cancer progression
    • Chen X, Gong J, Zeng H, et al. MicroRNA145 targets BNIP3 and suppresses prostate cancer progression. Cancer Res 2010;70:2728-38.
    • (2010) Cancer Res , vol.70 , pp. 2728-2738
    • Chen, X.1    Gong, J.2    Zeng, H.3
  • 38
    • 67449087324 scopus 로고    scopus 로고
    • Identification of novel microRNA targets based on microRNA signatures in bladder cancer
    • Ichimi T, Enokida H, Okuno Y, et al. Identification of novel microRNA targets based on microRNA signatures in bladder cancer. Int J Cance 2009;125:345-52.
    • (2009) Int J Cance , vol.125 , pp. 345-352
    • Ichimi, T.1    Enokida, H.2    Okuno, Y.3
  • 39
    • 77649271930 scopus 로고    scopus 로고
    • miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
    • Chiyomaru T, Enokida H, Tatarano S, et al. miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer 2010;102:883-91.
    • (2010) Br J Cancer , vol.102 , pp. 883-891
    • Chiyomaru, T.1    Enokida, H.2    Tatarano, S.3
  • 40
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, et al. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009;137:647-58.
    • (2009) Cell , vol.137 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3
  • 41
    • 78650857350 scopus 로고    scopus 로고
    • The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
    • Fang X, Yoon JG, Li L, et al. The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis. BMC Genomics 2011;12:11.
    • (2011) BMC Genomics , vol.12 , pp. 11
    • Fang, X.1    Yoon, J.G.2    Li, L.3
  • 42
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008;10:593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 43
    • 58149239686 scopus 로고    scopus 로고
    • Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
    • Varambally S, Cao Q, Mani RS, et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 2008;322:1695-9.
    • (2008) Science , vol.322 , pp. 1695-1699
    • Varambally, S.1    Cao, Q.2    Mani, R.S.3
  • 44
    • 64949190804 scopus 로고    scopus 로고
    • miR-449a targets HDAC-1 and induces growth arrest in prostate cancer
    • Noonan EJ, Place RF, Pookot D, et al. miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. Oncogene 2009;28:1714-24.
    • (2009) Oncogene , vol.28 , pp. 1714-1724
    • Noonan, E.J.1    Place, R.F.2    Pookot, D.3
  • 45
    • 20444479428 scopus 로고    scopus 로고
    • c-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller KI, et al. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-43.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3
  • 46
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007;447:1130-4.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3
  • 47
    • 67749143728 scopus 로고    scopus 로고
    • Modulation of microRNA processing by p53
    • Suzuki HI, Yamagata K, Sugimoto K, et al. Modulation of microRNA processing by p53. Nature 2009;460:529-33.
    • (2009) Nature , vol.460 , pp. 529-533
    • Suzuki, H.I.1    Yamagata, K.2    Sugimoto, K.3
  • 48
    • 74149083873 scopus 로고    scopus 로고
    • Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes
    • Takeshita F, Patrawala L, Osaki M, et al. Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 2010;18:181-7.
    • (2010) Mol Ther , vol.18 , pp. 181-187
    • Takeshita, F.1    Patrawala, L.2    Osaki, M.3
  • 49
    • 76349098935 scopus 로고    scopus 로고
    • Comparative profiling of genes and miRNAs expressed in the newborn, young adult, and aged human epididymides
    • Zhang J, Liu Q, Zhang W, et al. Comparative profiling of genes and miRNAs expressed in the newborn, young adult, and aged human epididymides. Acta Biochim Biophys Sin (Shanghai) 2010;42:145-53.
    • (2010) Acta Biochim Biophys Sin (Shanghai) , vol.42 , pp. 145-153
    • Zhang, J.1    Liu, Q.2    Zhang, W.3
  • 50
    • 82755162444 scopus 로고    scopus 로고
    • Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility
    • Wang C, Yang C, Chen X, et al. Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility. Clin Chem 2011;57:1722-31.
    • (2011) Clin Chem , vol.57 , pp. 1722-1731
    • Wang, C.1    Yang, C.2    Chen, X.3
  • 51
    • 61649128555 scopus 로고    scopus 로고
    • Altered microRNA expression in patients with non-obstructive azoospermia
    • Lian J, Zhang X, Tian H, et al. Altered microRNA expression in patients with non-obstructive azoospermia. Reprod Biol Endocrinol 2009;7:13.
    • (2009) Reprod Biol Endocrinol , vol.7 , pp. 13
    • Lian, J.1    Zhang, X.2    Tian, H.3
  • 52
    • 45849129864 scopus 로고    scopus 로고
    • MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis
    • Hayashi K, Chuva de Sousa Lopes SM, Kaneda M, et al. MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS One 2008;3:e1738.
    • (2008) PLoS One , vol.3
    • Hayashi, K.1    Chuva de Sousa Lopes, S.M.2    Kaneda, M.3
  • 53
    • 77950822671 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility
    • Nicoloso MS, Sun H, Spizzo R, et al. Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res 2010;70:2789-98.
    • (2010) Cancer Res , vol.70 , pp. 2789-2798
    • Nicoloso, M.S.1    Sun, H.2    Spizzo, R.3
  • 54
    • 79955644649 scopus 로고    scopus 로고
    • Polymorphisms in microRNA targets: a source of new molecular markers for male reproduction
    • Ogorevc J, Dovc P, Kunej T. Polymorphisms in microRNA targets: a source of new molecular markers for male reproduction. Asian J Androl 2011;13:505-8.
    • (2011) Asian J Androl , vol.13 , pp. 505-508
    • Ogorevc, J.1    Dovc, P.2    Kunej, T.3
  • 55
    • 79953089167 scopus 로고    scopus 로고
    • PIWI-interacting small RNAs: the vanguard of genome defence
    • Siomi MC, Sato K, Pezic D, et al. PIWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol 2011;12:246-58.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 246-258
    • Siomi, M.C.1    Sato, K.2    Pezic, D.3
  • 56
    • 36048937264 scopus 로고    scopus 로고
    • An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster
    • Yin H, Lin H. An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature 2007;450:304-8.
    • (2007) Nature , vol.450 , pp. 304-308
    • Yin, H.1    Lin, H.2
  • 57
    • 38849167412 scopus 로고    scopus 로고
    • Biogenesis and germline functions of piRNAs
    • Klattenhoff C, Theurkauf W. Biogenesis and germline functions of piRNAs. Development 2008;135:3-9.
    • (2008) Development , vol.135 , pp. 3-9
    • Klattenhoff, C.1    Theurkauf, W.2
  • 58
    • 0036083480 scopus 로고    scopus 로고
    • miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis
    • Deng W, Lin H. miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell 2002;2:819-30.
    • (2002) Dev Cell , vol.2 , pp. 819-830
    • Deng, W.1    Lin, H.2
  • 59
    • 10744223519 scopus 로고    scopus 로고
    • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
    • Kuramochi-Miyagawa S, Kimura T, Ijiri TW, et al. Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development 2004;131:839-49.
    • (2004) Development , vol.131 , pp. 839-849
    • Kuramochi-Miyagawa, S.1    Kimura, T.2    Ijiri, T.W.3
  • 60
    • 33947720638 scopus 로고    scopus 로고
    • MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline
    • Carmell MA, Girard A, van de Kant HJ, et al. MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 2007;12:503-14.
    • (2007) Dev Cell , vol.12 , pp. 503-514
    • Carmell, M.A.1    Girard, A.2    van de Kant, H.J.3
  • 61
    • 78649518098 scopus 로고    scopus 로고
    • Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population
    • Gu A, Ji G, Shi X, et al. Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population. Hum Reprod 2010;25:2955-61.
    • (2010) Hum Reprod , vol.25 , pp. 2955-2961
    • Gu, A.1    Ji, G.2    Shi, X.3
  • 62
    • 84866992734 scopus 로고    scopus 로고
    • Piwis and piwi-interacting RNAs in the epigenetics of cancer
    • [Epub ahead of print]
    • Siddiqi S, Matushansky I. Piwis and piwi-interacting RNAs in the epigenetics of cancer. J Cell Biochem 2011. [Epub ahead of print]
    • (2011) J Cell Biochem
    • Siddiqi, S.1    Matushansky, I.2
  • 63
    • 33847044299 scopus 로고    scopus 로고
    • Expression of the stem cell selfrenewal gene Hiwi and risk of tumour-related death in patients with softtissue sarcoma
    • Taubert H, Greither T, Kaushal D, et al. Expression of the stem cell selfrenewal gene Hiwi and risk of tumour-related death in patients with softtissue sarcoma. Oncogene 2007;26:1098-100.
    • (2007) Oncogene , vol.26 , pp. 1098-1100
    • Taubert, H.1    Greither, T.2    Kaushal, D.3
  • 64
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998;391:806-11.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 65
    • 44349130233 scopus 로고    scopus 로고
    • Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
    • Watanabe T, Totoki Y, Toyoda A, et al. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature 2008;453:539-43.
    • (2008) Nature , vol.453 , pp. 539-543
    • Watanabe, T.1    Totoki, Y.2    Toyoda, A.3
  • 66
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison PJ, Caudy AA, Bernstein E, et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 2002;16:948-58.
    • (2002) Genes Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3
  • 67
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 68
    • 65249135054 scopus 로고    scopus 로고
    • Knockdown of survivin expression by siRNAs enhances chemosensitivity of prostate cancer cells and attenuates its tumorigenicity
    • Shen J, Liu J, Long Y, et al. Knockdown of survivin expression by siRNAs enhances chemosensitivity of prostate cancer cells and attenuates its tumorigenicity. Acta Biochim Biophys Sin (Shanghai) 2009;41:223-30.
    • (2009) Acta Biochim Biophys Sin (Shanghai) , vol.41 , pp. 223-230
    • Shen, J.1    Liu, J.2    Long, Y.3
  • 69
    • 33750824851 scopus 로고    scopus 로고
    • Effect of small interfering RNA targeting survivin gene on biological behaviour of bladder cancer
    • Hou JQ, He J, Wang XL, et al. Effect of small interfering RNA targeting survivin gene on biological behaviour of bladder cancer. Chin Med J (Engl) 2006;119:1734-9.
    • (2006) Chin Med J (Engl) , vol.119 , pp. 1734-1739
    • Hou, J.Q.1    He, J.2    Wang, X.L.3
  • 70
    • 0034880019 scopus 로고    scopus 로고
    • The effect of antisense Bcl-2 oligonucleotides on Bcl-2 protein expression and apoptosis in human bladder transitional cell carcinoma
    • Duggan BJ, Maxwell P, Kelly JD, et al. The effect of antisense Bcl-2 oligonucleotides on Bcl-2 protein expression and apoptosis in human bladder transitional cell carcinoma. J Urol 2001;166:1098-105.
    • (2001) J Urol , vol.166 , pp. 1098-1105
    • Duggan, B.J.1    Maxwell, P.2    Kelly, J.D.3
  • 71
    • 24344455107 scopus 로고    scopus 로고
    • Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo
    • Gao L, Zhang L, Hu J, et al. Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo. Clin Cancer Res 2005;11:6333-41.
    • (2005) Clin Cancer Res , vol.11 , pp. 6333-6341
    • Gao, L.1    Zhang, L.2    Hu, J.3
  • 72
    • 32244446198 scopus 로고    scopus 로고
    • EphB4 receptor tyrosine kinase is expressed in bladder cancer and provides signals for cell survival
    • Xia G, Kumar SR, Stein JP, et al. EphB4 receptor tyrosine kinase is expressed in bladder cancer and provides signals for cell survival. Oncogene 2006;25:769-80.
    • (2006) Oncogene , vol.25 , pp. 769-780
    • Xia, G.1    Kumar, S.R.2    Stein, J.P.3
  • 73
    • 20144387142 scopus 로고    scopus 로고
    • Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer
    • Nogawa M, Yuasa T, Kimura S, et al. Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer. J Clin Invest 2005;115:978-85.
    • (2005) J Clin Invest , vol.115 , pp. 978-985
    • Nogawa, M.1    Yuasa, T.2    Kimura, S.3
  • 74
    • 79960965895 scopus 로고    scopus 로고
    • Combined gene expression profiling and RNAi screening in clear cell renal cell carcinoma identify PLK1 and other therapeutic kinase targets
    • Ding Y, Huang D, Zhang Z, et al. Combined gene expression profiling and RNAi screening in clear cell renal cell carcinoma identify PLK1 and other therapeutic kinase targets. Cancer Res 2011;71:5225-34.
    • (2011) Cancer Res , vol.71 , pp. 5225-5234
    • Ding, Y.1    Huang, D.2    Zhang, Z.3
  • 75
    • 78650192268 scopus 로고    scopus 로고
    • Suppression of SOCS3 increases susceptibility of renal cell carcinoma to interferon-a
    • Tomita S, Ishibashi K, Hashimoto K, et al. Suppression of SOCS3 increases susceptibility of renal cell carcinoma to interferon-a. Cancer Sci 2011;102:57-63.
    • (2011) Cancer Sci , vol.102 , pp. 57-63
    • Tomita, S.1    Ishibashi, K.2    Hashimoto, K.3
  • 76
    • 79953323468 scopus 로고    scopus 로고
    • FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer
    • Watkins SK, Zhu Z, Riboldi E, et al. FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer. J Clin Invest 2011;121:1361-72.
    • (2011) J Clin Invest , vol.121 , pp. 1361-1372
    • Watkins, S.K.1    Zhu, Z.2    Riboldi, E.3
  • 77
    • 25144501954 scopus 로고    scopus 로고
    • Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model
    • Bisanz K, Yu J, Edlund M, et al. Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model. Mol Ther 2005;12:634-43.
    • (2005) Mol Ther , vol.12 , pp. 634-643
    • Bisanz, K.1    Yu, J.2    Edlund, M.3
  • 78
    • 33947728944 scopus 로고    scopus 로고
    • Synergistic effect of survivin-specific small interfering RNA and topotecan in renal cancer cells: topotecan enhances liposome-mediated transfection by increasing cellular uptake
    • Sato A, Ito K, Asano T, et al. Synergistic effect of survivin-specific small interfering RNA and topotecan in renal cancer cells: topotecan enhances liposome-mediated transfection by increasing cellular uptake. Int J Oncol 2007;30:695-700.
    • (2007) Int J Oncol , vol.30 , pp. 695-700
    • Sato, A.1    Ito, K.2    Asano, T.3
  • 79
    • 33747031960 scopus 로고    scopus 로고
    • Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
    • McNamara JO 2nd, Andrechek ER, Wang Y, et al. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat Biotechnol 2006;24:1005-15.
    • (2006) Nat Biotechnol , vol.24 , pp. 1005-1015
    • McNamara II, J.O.1    Andrechek, E.R.2    Wang, Y.3
  • 80
    • 23744435317 scopus 로고    scopus 로고
    • Improving erectile function by silencing phosphodiesterase-5
    • Lin G, Hayashi N, Carrion R, et al. Improving erectile function by silencing phosphodiesterase-5. J Urol 2005;174:1142-8.
    • (2005) J Urol , vol.174 , pp. 1142-1148
    • Lin, G.1    Hayashi, N.2    Carrion, R.3
  • 81
    • 39049178309 scopus 로고    scopus 로고
    • [Phosphodiesterase type 5 siRNA increases cGMP in the smooth muscle cells of human corpus cavernosum]
    • Chen GQ, Bai WJ, Wang XF, et al. [Phosphodiesterase type 5 siRNA increases cGMP in the smooth muscle cells of human corpus cavernosum]. Zhonghua Nan Ke Xue 2006;12:979-81, 984.
    • (2006) Zhonghua Nan Ke Xue , vol.12
    • Chen, G.Q.1    Bai, W.J.2    Wang, X.F.3
  • 82
    • 77953646364 scopus 로고    scopus 로고
    • [Impact of rAd5-shRNA- PDE5A3 on cGMP in the smooth muscle cells of human corpus cavernosum]
    • Pan YG, Liu JH, Zhan Y, et al. [Impact of rAd5-shRNA- PDE5A3 on cGMP in the smooth muscle cells of human corpus cavernosum]. Zhonghua Nan Ke Xue 2009;15:689-92.
    • (2009) Zhonghua Nan Ke Xue , vol.15 , pp. 689-692
    • Pan, Y.G.1    Liu, J.H.2    Zhan, Y.3
  • 83
    • 34249083476 scopus 로고    scopus 로고
    • Antisense and short hairpin RNA (shRNA) constructs targeting PIN (Protein Inhibitor of NOS) ameliorate aging-related erectile dysfunction in the rat
    • Magee TR, Kovanecz I, Davila HH, et al. Antisense and short hairpin RNA (shRNA) constructs targeting PIN (Protein Inhibitor of NOS) ameliorate aging-related erectile dysfunction in the rat. J Sex Med 2007;4:633-43.
    • (2007) J Sex Med , vol.4 , pp. 633-643
    • Magee, T.R.1    Kovanecz, I.2    Davila, H.H.3
  • 84
    • 35748929690 scopus 로고    scopus 로고
    • [Small interfering RNA inhibits the expression of connexin43 in the human corpus cavernosum penis smooth muscle cells]
    • Cao ZG, Zhu YP, Sun YW, et al. [Small interfering RNA inhibits the expression of connexin43 in the human corpus cavernosum penis smooth muscle cells]. Zhonghua Nan Ke Xue 2007;13:440-3.
    • (2007) Zhonghua Nan Ke Xue , vol.13 , pp. 440-443
    • Cao, Z.G.1    Zhu, Y.P.2    Sun, Y.W.3
  • 85
    • 41649118729 scopus 로고    scopus 로고
    • Antitumor effect of dsRNA-induced p21(WAF1/CIP1) gene activation in human bladder cancer cells
    • Chen Z, Place RF, Jia ZJ, et al. Antitumor effect of dsRNA-induced p21(WAF1/CIP1) gene activation in human bladder cancer cells. Mol Cancer Ther 2008;7:698-703.
    • (2008) Mol Cancer Ther , vol.7 , pp. 698-703
    • Chen, Z.1    Place, R.F.2    Jia, Z.J.3
  • 86
    • 43949099936 scopus 로고    scopus 로고
    • Up-regulation of p21WAF1/Cip1 by saRNA induces G1-phase arrest and apoptosis in T24 human bladder cancer cells
    • Yang K, Zheng XY, Qin J, et al. Up-regulation of p21WAF1/Cip1 by saRNA induces G1-phase arrest and apoptosis in T24 human bladder cancer cells. Cancer Lett 2008;265:206-14.
    • (2008) Cancer Lett , vol.265 , pp. 206-214
    • Yang, K.1    Zheng, X.Y.2    Qin, J.3
  • 87
    • 67449097427 scopus 로고    scopus 로고
    • Double stranded-RNA-mediated activation of P21 gene induced apoptosis and cell cycle arrest in renal cell carcinoma
    • Whitson JM, Noonan EJ, Pookot D, et al. Double stranded-RNA-mediated activation of P21 gene induced apoptosis and cell cycle arrest in renal cell carcinoma. Int J Cancer 2009;125:446-52.
    • (2009) Int J Cancer , vol.125 , pp. 446-452
    • Whitson, J.M.1    Noonan, E.J.2    Pookot, D.3
  • 88
    • 51449104525 scopus 로고    scopus 로고
    • Up-regulation of E-cadherin by small activating RNA inhibits cell invasion and migration in 5637 human bladder cancer cells
    • Mao Q, Li Y, Zheng X, et al. Up-regulation of E-cadherin by small activating RNA inhibits cell invasion and migration in 5637 human bladder cancer cells. Biochem Biophys Res Commun 2008;375:566-70.
    • (2008) Biochem Biophys Res Commun , vol.375 , pp. 566-570
    • Mao, Q.1    Li, Y.2    Zheng, X.3
  • 89
    • 78649252302 scopus 로고    scopus 로고
    • Suppression of migration and invasion of PC3 prostate cancer cell line via activating E-cadherin expression by small activating RNA
    • Mao Q, Zheng X, Yang K, et al. Suppression of migration and invasion of PC3 prostate cancer cell line via activating E-cadherin expression by small activating RNA. Cancer Invest 2010;28:1013-8.
    • (2010) Cancer Invest , vol.28 , pp. 1013-1018
    • Mao, Q.1    Zheng, X.2    Yang, K.3
  • 90
    • 77749320938 scopus 로고    scopus 로고
    • RNAa is conserved in mammalian cells
    • Huang V, Qin Y, Wang J, et al. RNAa is conserved in mammalian cells. PLoS One 2010;5:e8848.
    • (2010) PLoS One , vol.5
    • Huang, V.1    Qin, Y.2    Wang, J.3
  • 91
    • 78650318077 scopus 로고    scopus 로고
    • Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration
    • Wang J, Place RF, Huang V, et al. Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res 2010;70:10182-91.
    • (2010) Cancer Res , vol.70 , pp. 10182-10191
    • Wang, J.1    Place, R.F.2    Huang, V.3
  • 92
    • 84863229533 scopus 로고    scopus 로고
    • Upregulation of Cyclin B1 by miRNA and its implications in cancer
    • Nov 3. 2011 DOI: 10.1093/nar/gkr934
    • Huang V, Place RF, Portnoy V, et al. Upregulation of Cyclin B1 by miRNA and its implications in cancer. Nucleic Acids Res 2011 Nov 3. 2011 DOI: 10.1093/nar/gkr934.
    • (2011) Nucleic Acids Res
    • Huang, V.1    Place, R.F.2    Portnoy, V.3
  • 93
    • 0037300192 scopus 로고    scopus 로고
    • Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virusmediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats
    • Rogers RS, Graziottin TM, Lin CS, et al. Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virusmediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats. Int J Impot Res 2003;15:26-37.
    • (2003) Int J Impot Res , vol.15 , pp. 26-37
    • Rogers, R.S.1    Graziottin, T.M.2    Lin, C.S.3
  • 94
    • 80053573084 scopus 로고    scopus 로고
    • Up-regulation of VEGF by small activator RNA in human corpus cavernosum smooth muscle cells
    • Chen R, Wang T, Rao K, et al. Up-regulation of VEGF by small activator RNA in human corpus cavernosum smooth muscle cells. J Sex Med 2011;8:2773-80.
    • (2011) J Sex Med , vol.8 , pp. 2773-2780
    • Chen, R.1    Wang, T.2    Rao, K.3
  • 95
    • 70349239135 scopus 로고    scopus 로고
    • Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy
    • Turunen MP, Lehtola T, Heinonen SE, et al. Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy. Circ Res 2009;105:604-9.
    • (2009) Circ Res , vol.105 , pp. 604-609
    • Turunen, M.P.1    Lehtola, T.2    Heinonen, S.E.3
  • 96
    • 78650624101 scopus 로고    scopus 로고
    • RNA interference in the clinic: challenges and future directions
    • Pecot CV, Calin GA, Coleman RL, et al. RNA interference in the clinic: challenges and future directions. Nat Rev Cance 2011;11:59-67.
    • (2011) Nat Rev Cance , vol.11 , pp. 59-67
    • Pecot, C.V.1    Calin, G.A.2    Coleman, R.L.3
  • 97
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • Davis ME, Zuckerman JE, Choi CH, et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010;464:1067-70.
    • (2010) Nature , vol.464 , pp. 1067-1070
    • Davis, M.E.1    Zuckerman, J.E.2    Choi, C.H.3


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