Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator

Journal of the American Chemical Society

Volumn 131, Issue 40, 2009, Pages 14240-14242

  Majmudar, Chinmay Y ^a   Lee, Lori W ^a   Lancia, Jody K ^a   Nwokoye, Adaora ^a   Wang, Qian ^b   Wands, Amberlyn M ^a   Wang, Lei ^b   Mapp, Anna K ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING INTERFACE; BINDING MODES; BINDING PARTNERS; BIOLOGICAL NETWORKS; CELLULAR FUNCTION; GROWTH CONDITIONS; IN-VIVO; INHIBITOR PROTEINS; KEY BINDING; L-PHENYLALANINE; NON NATURAL AMINO ACIDS; PROTEIN-PROTEIN INTERACTIONS; S.CEREVISIAE; SMALL MOLECULES; SUPPRESSION SYSTEMS; TRANSCRIPTIONAL ACTIVATION DOMAIN; TRANSCRIPTIONAL ACTIVATORS; TRANSCRIPTIONAL ACTIVITY;

AMINATION; AMINES; AMINO ACIDS; BINDING ENERGY; ORGANIC ACIDS; TRANSCRIPTION FACTORS;

CHEMICAL ACTIVATION;

AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; TRANSCRIPTION FACTOR GAL4; TRANSCRIPTION FACTOR GAL80; UNCLASSIFIED DRUG;

ARTICLE; GENE MUTATION; IN VIVO STUDY; MUTAGENESIS; NONHUMAN; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BENZOPHENONES; DNA-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHENYLALANINE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

EID: 70349923890     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja904378z     Document Type: Article

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