Minimal activators that bind to the KIX domain of p300/CBP identified by phage display screening

Nature Biotechnology

Volumn 18, Issue 10 SUPPL., 2000, Pages 1080-1085

  Frangioni, John V ^a   LaRiccia, Leah M ^a   Cantley, Lewis C ^a   Montminy, Marc R ^b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

CREB binding protein; Gene therapy; P300; Phage display; Transcriptional control

Indexed keywords

CREBBP PROTEIN, MOUSE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA BINDING PROTEIN; E1A ASSOCIATED P300 PROTEIN; EP300 PROTEIN, MOUSE; HYBRID PROTEIN; NUCLEAR PROTEIN; OLIGOPEPTIDE; PEPTIDE LIBRARY; TRANSACTIVATOR PROTEIN; BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN P300; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REPORTER GENE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRANSACTIVATION; DNA BINDING; GENE LIBRARY; GENETIC TRANSCRIPTION; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CREB-BINDING PROTEIN; DNA-BINDING PROTEINS; E1A-ASSOCIATED P300 PROTEIN; GENES, REPORTER; MICE; MODELS, MOLECULAR; NUCLEAR PROTEINS; OLIGOPEPTIDES; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSFECTION;

EID: 0033623252     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/80280     Document Type: Article

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