Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium

Chemico-Biological Interactions

Volumn 200, Issue 1, 2012, Pages 45-64

  Kirman, C R ^a   Hays, S M ^a   Aylward, L L ^a   Suh, M ^b   Harris, M A ^c   Thompson, C M ^c   Haws, L C ^d   Proctor, D M ^b  

^a LLP   (United States)

^b ToxStrategies   (United States)

^c ToxStrategies   (United States)

^d ToxStrategies   (United States)

Author keywords

Chromium; Gastrointestinal tract; Physiologically based model; Rodents; Toxicokinetics

Indexed keywords

CHROMIUM; DRINKING WATER;

ANIMAL TISSUE; ARTICLE; BLOOD; BLOOD LEVEL; BODY WEIGHT; CARCINOGENESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DUODENUM; EXPOSURE; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TRANSIT; ILEUM; INTESTINE TUMOR; JEJUNUM; KIDNEY; LIVER; LONG TERM EXPOSURE; MOUSE; MOUTH; NONHUMAN; PH; RAT; REACTION TIME; STOMACH; TISSUE DISTRIBUTION; TISSUE LEVEL; TOXICOKINETICS; URINARY EXCRETION;

ADMINISTRATION, ORAL; ANIMALS; CHROMIUM; DRINKING WATER; FEMALE; HUMANS; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; MICE; MODELS, BIOLOGICAL; RATS; WATER POLLUTANTS, CHEMICAL;

MUS; RATTUS; RODENTIA;

EID: 84868102716     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.08.016     Document Type: Article

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