Lack of toxicity of chromium chloride and chromium picolinate in rats

Journal of the American College of Nutrition

Volumn 16, Issue 3, 1997, Pages 273-279

  Anderson, Richard A ^a   Bryden, NoeUa A ^a   Polansky, Marilyn M ^a  

^a BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

Author keywords

Chromium; Kidney; Liver; Picolinic acid; Tissue chromium; Toxicity

Indexed keywords

AMINOTRANSFERASE; CHOLESTEROL; CHROMIUM; CHROMIUM CHLORIDE; CHROMIUM PICOLINATE; CREATININE; GLUCOSE; LACTATE DEHYDROGENASE; PROTEIN; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; DRUG BIOAVAILABILITY; DRUG SAFETY; HISTOPATHOLOGY; NONHUMAN; RAT;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CHLORIDES; CHOLESTEROL; CHROMIUM COMPOUNDS; DIET; IRON CHELATING AGENTS; KIDNEY; LIVER; ORGAN SIZE; PICOLINIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030955871     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.1997.10718685     Document Type: Article

References (27)

1. National Research Council: "Recommended Dietary Allowance," 10th Edition. Washington, DC: National Academy Press, pp 241-243, 1989.
2. AndersonRA: Chromium, glucose tolerance, diabetes and lipid metabolism. J Advancement Med8:37-49, 1995.
3. AndersonRA: Recent advances in the clinical and biochemical effects of chromium deficiency. In Prasad AS (ed): "Essential and Toxic Trace Elements in Human Health and Disease." New York: Wiley Liss Inc, pp 221-234, 1993.
4. EvansGW: The effect of chromium picolinate on insulin controlled parameters in humans. Inti J Biosoc Med Res11:163-180, 1989.
5. HastenDL, RomeEP, FranksBD, HegstedM: Effects of chromium picolinate on beginning weight training students. Inti J Sports Nutr2:343-350, 1992.
6. PageTG, SouthernLL, WardTL, ThompsonDL, Jr: Effect of chromium picolinate on growth and serum and carcass traits of growing-finishing pigs. J Anim Sci71:656-662, 1993.
7. LindemannMD, WoodCM, HarperAF, KornegayET, AndersonRA: Dietary chromium picolinate additions improve gain:feed and carcass characteristics in growing-finishing pigs and increase litter size in reproducing sows. J Anim Sci73:457-465, 1995.
8. KaatsGR, WiseJA, BlumK, MorinRJ, AdelmanJA, CraigJ, CroftHA: The short-term therapeutic efficacy of treating obesity with a plan of improved nutrition and moderate calorie restriction. Current Therapeutic Res51:261-274, 1992.
9. Jovanovic-PetersonL, GutierrezM, PetersonCM: Chromium Supplementation for gestational diabetic women improves glucose tolerance and decreases hyperinsulinemia (Abstract). J Am ColJ Nutr14:530, 1995.
10. AndersonRA, KozlovskyAS: Chromium intake, absorption and excretion of subjects consuming self-selected diets. Am J Clin Nutr41:1177-1183, 1985.
11. BunkerW, LawsonMS, DelvesHT, ClaytonBE: The uptake and excretion of chromium by the elderly. Am J Clin Nutr39:797-802, 1984.
12. KoivistoinenP: Mineral element composition of Finnish foods: N, K, Ca, Mg, P, S, Fe, Cu, Mn, Zn, Mo, Co, Ni, Ca, F, Se, Si, Rb, AI, B, Br, Hg, As, Cd, Pb and Ash. Acta Agric Scand Suppl22:165-171,1980.
13. AndersonRA, BrydenNA, PolanskyMM: Dietary chromium intake-freely chosen diets, institutional diets and individual foods. Bioi Trace Elem Res32:117-121,1992.
14. KatzSA, SalemH: "The Biological Environmental Chemistry of Chromium." New York: VCH Publishers, 1994.
15. MertzW, AbernathyCO, OlinSS: "Risk Assessment of Essential Elements." Washington DC: ILSI Press, pp xix-xxviii, 1994.
16. IvankovicS, PreussmannR: Absence of toxic and carcinogenic effects after administration of high doses of chromic oxide pigment in subacute and long-term feeding experiments in rats. Food Cosmet Toxicol13:347-351, 1975.
17. DoursonML: The chromium reference doses. In Mertz W, Abernathy CO, Olin SS (eds): "Risk Assessment of Essential Elements." Washington DC: ILSI Press, pp 207-212, 1994.
18. MeenakshiCE, PadminiE, MotlagDB: Comparative toxicity of trivalent and hexavalent chromium in rats. Indian J Environ Hlth31:250-256, 1989.
19. StemsDM, WiseJP, Sr, PatternoSR, WetterhahnKE: Chromium picolinate produces chromosome damage in Chinese hamster ovary cells. FASEB J9:1643-1648, 1995.
20. AndersonRA, BrydenNA, PolanskyMM, GautschiK: Dietary chromium effects on tissue chromium concentrations and chromium absorption in rats. J Trace Elem Exptl Med9:11-25, 1996.
21. AndersonRA: Stress effects on chromium nutrition in humans and farm animals. In Lyon TP, Jacques KA (eds): "Biotechnology in the Feed Industry." London: Notingham Univ Press, pp 267-274, 1994.
22. FregertS, RorsmanH: Allergy to trivalent chromium. Arch Dermatol90:4-6, 1964.
23. CohenHA: Carrier specificity of tuberculin-type reactions to trivalent chromium. Arch Dermatol93:34-40, 1966.
24. AndersonRA, PolanskyMM, BrydenNA, ZawadzkiJ: Selective uptake of chromium in type II diabetes mellitus. (Abstract). FASEB J10:A820, 1996.
25. StemsDM, BelbrunoJJ, WetterhahnKE: A prediction of chromium (III) accumulation in humans from chromium dietary Supplements. FASEB J9:1649-1655, 1995.
26. SamitzMH: A current review of the chromate problem. Derrnatol Dig3:18-23. 1964.
27. MackenzieRD. ByerrumRU. DeckerCF, HoppertCA, LanghamRF: Chromic toxicity studies. Hexavalent and trivalent chromium administered in drinking water to rats. Am Arch Ind Hlth 18:232-234, 1958.