Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 44, 2012, Pages 17948-17953

  Barrow, Joeva J ^a   Masannat, Jude ^a   Bungert, Jörg ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Artificial transcription factor; Gene regulation; Red cell

Indexed keywords

ERYTHROCYTE BAND 4.9 PROTEIN; HEMOGLOBIN BETA CHAIN; SPECTRIN; SPECTRIN BETA SUBUNIT; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DNA BINDING; DNA SEQUENCE; EMBRYO DEVELOPMENT; ERYTHROLEUKEMIA CELL; GENE CONTROL; GENE EXPRESSION; GENE LOCUS; IN VITRO STUDY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; ZINC FINGER MOTIF;

ANIMALS; BETA-GLOBINS; BINDING SITES; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; POLYMERASE CHAIN REACTION; ZINC FINGERS;

EID: 84868089898     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1207677109     Document Type: Article

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