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Volumn 10, Issue 2, 1998, Pages 158-165

Transcriptional regulation of B-cell differentiation

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 0344734109     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(98)80244-6     Document Type: Article
Times cited : (60)

References (64)
  • 1
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med. 173:1991;1213-1225.
    • (1991) J Exp Med , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 2
    • 0027247802 scopus 로고
    • B lymphopoiesis in the mouse
    • Rolink A, Melchers F. B lymphopoiesis in the mouse. Adv Immunol. 53:1993;123-156.
    • (1993) Adv Immunol , vol.53 , pp. 123-156
    • Rolink, A.1    Melchers, F.2
  • 3
    • 0030483542 scopus 로고    scopus 로고
    • Identification of the earliest B lineage stage in mouse bone marrow
    • Li YS, Wasserman R, Hayakawa K, Hardy RR. Identification of the earliest B lineage stage in mouse bone marrow. Immunity. 5:1996;527-535.
    • (1996) Immunity , vol.5 , pp. 527-535
    • Li, Y.S.1    Wasserman, R.2    Hayakawa, K.3    Hardy, R.R.4
  • 4
    • 0027363528 scopus 로고
    • Hematopoietic lineage- And stage-restricted expression of the ETS oncogene family member PU.1
    • Hromas R, Orazi A, Neiman R, Maki R, Van Beveran C, Moore J, Klemsz M. Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1. Blood. 82:1993;2998-3004.
    • (1993) Blood , vol.82 , pp. 2998-3004
    • Hromas, R.1    Orazi, A.2    Neiman, R.3    Maki, R.4    Van Beveran, C.5    Moore, J.6    Klemsz, M.7
  • 5
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott EW, Simon MC, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science. 265:1994;1573-1577.
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 6
    • 0029550341 scopus 로고
    • PU.1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation
    • Olson MC, Scott EW, Hack AA, Su GH, Tenen DG, Singh H, Simon MC. PU.1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation. Immunity. 3:1995;703-714.
    • (1995) Immunity , vol.3 , pp. 703-714
    • Olson, M.C.1    Scott, E.W.2    Hack, A.A.3    Su, G.H.4    Tenen, D.G.5    Singh, H.6    Simon, M.C.7
  • 7
    • 0030611964 scopus 로고    scopus 로고
    • Pu.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
    • of outstanding interest. This paper provides valuable insight into the defects in the PU.1-deficent mice. It demonstrates the cell-autonomous nature of the requirement for PU.1 and defines defects in the stem cell compartment that suggest that the loss of myeloid and B cells in these mice is due to a problem with a putative common progenitor.
    • of outstanding interest Scott EW, Fisher RC, Olson MC, Kehrli EW, Simon MC, Singh H. Pu.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity. 6:1997;437-447 This paper provides valuable insight into the defects in the PU.1-deficent mice. It demonstrates the cell-autonomous nature of the requirement for PU.1 and defines defects in the stem cell compartment that suggest that the loss of myeloid and B cells in these mice is due to a problem with a putative common progenitor.
    • (1997) Immunity , vol.6 , pp. 437-447
    • Scott, E.W.1    Fisher, R.C.2    Olson, M.C.3    Kehrli, E.W.4    Simon, M.C.5    Singh, H.6
  • 9
    • 0029073345 scopus 로고
    • Pip, a novel IRF family member, is a lymphoid-specific PU.1-dependent transcriptional activator
    • Eisenbeis CF, Singh H, Storb U. Pip, a novel IRF family member, is a lymphoid-specific PU.1-dependent transcriptional activator. Genes Dev. 9:1995;1377-1387.
    • (1995) Genes Dev , vol.9 , pp. 1377-1387
    • Eisenbeis, C.F.1    Singh, H.2    Storb, U.3
  • 10
    • 0031034118 scopus 로고    scopus 로고
    • PU.1 can participate in an active enhancer complex without its transcriptional activation domain
    • Pongubala JMR, Atchison ML. PU.1 can participate in an active enhancer complex without its transcriptional activation domain. Biochemistry. 94:1997;127-132.
    • (1997) Biochemistry , vol.94 , pp. 127-132
    • Pongubala, J.M.R.1    Atchison, M.L.2
  • 11
    • 0029763203 scopus 로고    scopus 로고
    • Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1
    • Brass AL, Kehrli E, Eisenbeis CF, Storb U, Singh H. Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. Genes Dev. 10:1996;2335-2347.
    • (1996) Genes Dev , vol.10 , pp. 2335-2347
    • Brass, A.L.1    Kehrli, E.2    Eisenbeis, C.F.3    Storb, U.4    Singh, H.5
  • 12
    • 0029928685 scopus 로고    scopus 로고
    • A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon regulated genes
    • Yamagata T, Nishida J, Tanaka T, Sakai R, Mitani K, Yoshida M, Taniguchi T, Yazaki Y, Hirai H. A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon regulated genes. Mol Cell Biol. 16:1996;1283-1294.
    • (1996) Mol Cell Biol , vol.16 , pp. 1283-1294
    • Yamagata, T.1    Nishida, J.2    Tanaka, T.3    Sakai, R.4    Mitani, K.5    Yoshida, M.6    Taniguchi, T.7    Yazaki, Y.8    Hirai, H.9
  • 14
    • 0030933151 scopus 로고    scopus 로고
    • The role of the Ikaros gene in lymphocyte development and homeostasis
    • Georgopoulos K, Winandy S, Avitahl N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annu Rev Immunol. 15:1997;155-176.
    • (1997) Annu Rev Immunol , vol.15 , pp. 155-176
    • Georgopoulos, K.1    Winandy, S.2    Avitahl, N.3
  • 15
    • 15144358621 scopus 로고    scopus 로고
    • Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin
    • of outstanding interest. This paper describes a novel member of the Ikaros family, Helios. Its specific expression on T cells provides a basis for postulating that the severe defects observed in the dominant-negative ikaros mutation may be due to blocking Helios' function. The paper also describes Helios' function as a repressor.
    • of outstanding interest Hahm K, Cobb BS, McCarty AS, Brown KE, Klug CA, Lee R, Akashi K, Weissman I, Fisher AG, Smale ST. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev. 12:1998;782-796 This paper describes a novel member of the Ikaros family, Helios. Its specific expression on T cells provides a basis for postulating that the severe defects observed in the dominant-negative ikaros mutation may be due to blocking Helios' function. The paper also describes Helios' function as a repressor.
    • (1998) Genes Dev , vol.12 , pp. 782-796
    • Hahm, K.1    Cobb, B.S.2    McCarty, A.S.3    Brown, K.E.4    Klug, C.A.5    Lee, R.6    Akashi, K.7    Weissman, I.8    Fisher, A.G.9    Smale, S.T.10
  • 16
    • 0031907815 scopus 로고    scopus 로고
    • Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes
    • Klug CA, Morrison SJ, Masek M, Hahm K, Smale ST, Weissman IL. Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. Proc Natl Acad Sci USA. 95:1998;657-662.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 657-662
    • Klug, C.A.1    Morrison, S.J.2    Masek, M.3    Hahm, K.4    Smale, S.T.5    Weissman, I.L.6
  • 17
    • 0030972497 scopus 로고    scopus 로고
    • Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation
    • Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, Gonzales E, Wu P, Neben S, Georgopoulos K. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J. 16:1997;2004-2013.
    • (1997) EMBO J , vol.16 , pp. 2004-2013
    • Morgan, B.1    Sun, L.2    Avitahl, N.3    Andrikopoulos, K.4    Ikeda, T.5    Gonzales, E.6    Wu, P.7    Neben, S.8    Georgopoulos, K.9
  • 18
    • 0025943384 scopus 로고
    • LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes
    • Lo K, Landau NR, Smale ST. LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes. Mol Cell Biol. 11:1991;5229-5243.
    • (1991) Mol Cell Biol , vol.11 , pp. 5229-5243
    • Lo, K.1    Landau, N.R.2    Smale, S.T.3
  • 19
    • 0029831978 scopus 로고    scopus 로고
    • Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development
    • Sun L, Liu A, Georgopoulos K. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. EMBO J. 15:1996;5358-5369.
    • (1996) EMBO J , vol.15 , pp. 5358-5369
    • Sun, L.1    Liu, A.2    Georgopoulos, K.3
  • 20
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal, adult lymphoid system in mice with an Ikaros null mutation
    • of outstanding interest. This paper describes the phenotype due to a null mutation of Ikaros (generated by disrupting the carboxyl terminus dimerization domain) and highlights the differences between this and the dominant negative mutation of Ikaros. It also provides interesting evidence for a very marked differential requirement for Ikaros between T cell development in the fetus and adult.
    • of outstanding interest Wang J-H, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M, Georgopoulos K. Selective defects in the development of the fetal, adult lymphoid system in mice with an Ikaros null mutation. Immunity. 6:1996;537-549 This paper describes the phenotype due to a null mutation of Ikaros (generated by disrupting the carboxyl terminus dimerization domain) and highlights the differences between this and the dominant negative mutation of Ikaros. It also provides interesting evidence for a very marked differential requirement for Ikaros between T cell development in the fetus and adult.
    • (1996) Immunity , vol.6 , pp. 537-549
    • Wang J-H1    Nichogiannopoulou, A.2    Wu, L.3    Sun, L.4    Sharpe, A.H.5    Bigby, M.6    Georgopoulos, K.7
  • 22
    • 0031437119 scopus 로고    scopus 로고
    • Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
    • of outstanding interest. This paper is the first to describe the localization of the Ikaros gene within the nucleus and reports that Ikaros is associated with heterochromatin and transcriptionally silent loci. These findings suggest that these proteins may be involved in repression of gene expression.
    • of outstanding interest Brown KE, Guest SS, Smale ST, Hahm K, Merkenschlager M, Fisher AG. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell. 91:1997;845-854 This paper is the first to describe the localization of the Ikaros gene within the nucleus and reports that Ikaros is associated with heterochromatin and transcriptionally silent loci. These findings suggest that these proteins may be involved in repression of gene expression.
    • (1997) Cell , vol.91 , pp. 845-854
    • Brown, K.E.1    Guest, S.S.2    Smale, S.T.3    Hahm, K.4    Merkenschlager, M.5    Fisher, A.G.6
  • 24
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B, I kappa B proteins: New discoveries and insights
    • Baldwin AS. The NF-kappa B, I kappa B proteins: new discoveries and insights. Annu Rev Immunol. 14:1996;649-683.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 25
    • 0030999057 scopus 로고    scopus 로고
    • NF-κB RelA-deficient lymphocytes: Normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses
    • Doi TS, Takahashi T, Taguchi O, Azuma T, Obata Y. NF-κB RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J Exp Med. 185:1997;953-961.
    • (1997) J Exp Med , vol.185 , pp. 953-961
    • Doi, T.S.1    Takahashi, T.2    Taguchi, O.3    Azuma, T.4    Obata, Y.5
  • 26
    • 0030837598 scopus 로고    scopus 로고
    • Failure of lymphopoiesis after adoptive transfer of NF-κB-deficient fetal liver cells
    • + cells, while mice lacking either one alone have relatively normal B-cell development. This paper is additionally interesting because it suggests that the loss of secreted, or cell bound signals from wild-type hematopoietic cells may be the basis for this defect.
    • + cells, while mice lacking either one alone have relatively normal B-cell development. This paper is additionally interesting because it suggests that the loss of secreted, or cell bound signals from wild-type hematopoietic cells may be the basis for this defect.
    • (1997) Immunity , vol.6 , pp. 765-772
    • Horwitz, B.H.1    Scott, M.L.2    Cherry, S.R.3    Bronson, R.T.4    Baltimore, D.5
  • 27
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune response
    • Sha WC, Liou H-C, Tuomanen EI, Baltimore D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune response. Cell. 80:1995;321-330.
    • (1995) Cell , vol.80 , pp. 321-330
    • Sha, W.C.1    Liou H-C2    Tuomanen, E.I.3    Baltimore, D.4
  • 28
    • 0030048332 scopus 로고    scopus 로고
    • B cells from p50/NF-κB knockout mice have selective defects in proliferation, differentiation, germ line CH transcription, and Ig class switching
    • Snapper CM, Zelazowski P, Rosas FR, Kehry MR, Tian M, Baltimore D, Sha WR. B cells from p50/NF-κB knockout mice have selective defects in proliferation, differentiation, germ line CH transcription, and Ig class switching. J Immunol. 156:1996;183-191.
    • (1996) J Immunol , vol.156 , pp. 183-191
    • Snapper, C.M.1    Zelazowski, P.2    Rosas, F.R.3    Kehry, M.R.4    Tian, M.5    Baltimore, D.6    Sha, W.R.7
  • 29
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family
    • Weih F, Carrasco D, Durham SK, Barton DS, Rizzo CA, Ryseck R-P, Lira SA, Bravo R. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family. Cell. 80:1995;331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck R-P6    Lira, S.A.7    Bravo, R.8
  • 30
    • 0029903486 scopus 로고    scopus 로고
    • B cells lacking relB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching
    • Snapper CM, Rosas FR, Zelazowski P, Moorman MA, Kehry MR, Bravo R, Weih F. B cells lacking relB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching. J Exp Med. 184:1996;1537-1541.
    • (1996) J Exp Med , vol.184 , pp. 1537-1541
    • Snapper, C.M.1    Rosas, F.R.2    Zelazowski, P.3    Moorman, M.A.4    Kehry, M.R.5    Bravo, R.6    Weih, F.7
  • 31
    • 0030292678 scopus 로고    scopus 로고
    • Both multiorgan inflammation and myeloid hyperplasia in relB-deficient mice are T cell dependent
    • Weih F, Durham SK, Barton DS, Sha WC, Baltimore D, Bravo R. Both multiorgan inflammation and myeloid hyperplasia in relB-deficient mice are T cell dependent. J Immunol. 157:1996;3974-3979.
    • (1996) J Immunol , vol.157 , pp. 3974-3979
    • Weih, F.1    Durham, S.K.2    Barton, D.S.3    Sha, W.C.4    Baltimore, D.5    Bravo, R.6
  • 34
    • 0026798829 scopus 로고
    • Helix-loop-helix proteins in the regulation of the immunoglobulin gene transcription
    • Kadesch T. Helix-loop-helix proteins in the regulation of the immunoglobulin gene transcription. Immunol Today. 13:1992;31-36.
    • (1992) Immunol Today , vol.13 , pp. 31-36
    • Kadesch, T.1
  • 35
    • 0029058035 scopus 로고
    • B cell specific DNA binding by an E47 homodimer
    • Shen CP, Kadesch T. B cell specific DNA binding by an E47 homodimer. Mol Cell Biol. 15:1995;4518-4524.
    • (1995) Mol Cell Biol , vol.15 , pp. 4518-4524
    • Shen, C.P.1    Kadesch, T.2
  • 36
  • 37
    • 0026045243 scopus 로고
    • Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre T-cell line
    • Schlissel MS, Voronova A, Baltimore D. Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre T-cell line. Genes Dev. 5:1991;1367-1376.
    • (1991) Genes Dev , vol.5 , pp. 1367-1376
    • Schlissel, M.S.1    Voronova, A.2    Baltimore, D.3
  • 40
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang Y, Soriano P, Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell. 79:1994;875-884.
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 42
    • 0029825698 scopus 로고    scopus 로고
    • Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle, B-cell differentiation
    • of special interest
    • of special interest Eckner R, Yao TP, Oldread E, Livingston DM. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle, B-cell differentiation. Genes Dev. 10:1996;2478-2490.
    • (1996) Genes Dev , vol.10 , pp. 2478-2490
    • Eckner, R.1    Yao, T.P.2    Oldread, E.3    Livingston, D.M.4
  • 43
    • 0029896451 scopus 로고    scopus 로고
    • B-Lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB
    • Using double-heterozygous mice, this paper demonstrates the functional redundancy between three members of the basic helix-loop-helix family of transcription factors.
    • Zhuang Y, Cheng P, Weintraub H. B-Lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol Cell Biol. 16:1996;2898-2905 Using double-heterozygous mice, this paper demonstrates the functional redundancy between three members of the basic helix-loop-helix family of transcription factors.
    • (1996) Mol Cell Biol , vol.16 , pp. 2898-2905
    • Zhuang, Y.1    Cheng, P.2    Weintraub, H.3
  • 44
    • 0027228167 scopus 로고
    • Localization of E2A-mRNA expression in developing and adult rat tissues
    • Roberts VJ, Steenbergen R, Murre C. Localization of E2A-mRNA expression in developing and adult rat tissues. Proc Natl Acad Sci USA. 90:1993;7583-7587.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7583-7587
    • Roberts, V.J.1    Steenbergen, R.2    Murre, C.3
  • 45
    • 0030221916 scopus 로고    scopus 로고
    • Involvement of the E2A basic helix-loop-helix protein immunoglobulin heavy chain class switching
    • Goldfarb AN, Flores JP, Lewandowska K. Involvement of the E2A basic helix-loop-helix protein immunoglobulin heavy chain class switching. Mol Immunol. 33:1996;947-956.
    • (1996) Mol Immunol , vol.33 , pp. 947-956
    • Goldfarb, A.N.1    Flores, J.P.2    Lewandowska, K.3
  • 46
    • 0026006396 scopus 로고
    • A novel lineage-specific nuclear factor regulates mb-1 gene transcription of the early stages of B cell differentiation
    • Hagman J, Travis A, Grosschedl R. A novel lineage-specific nuclear factor regulates mb-1 gene transcription of the early stages of B cell differentiation. EMBO J. 10:1991;3409-3417.
    • (1991) EMBO J , vol.10 , pp. 3409-3417
    • Hagman, J.1    Travis, A.2    Grosschedl, R.3
  • 47
    • 0029045161 scopus 로고
    • Failure of B-cell differentiation in mice lacking the transcription factor EBF
    • Lin H, Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature. 376:1995;263-267.
    • (1995) Nature , vol.376 , pp. 263-267
    • Lin, H.1    Grosschedl, R.2
  • 49
    • 0029099805 scopus 로고
    • The role of BSAP (Pax-5) in B-cell development
    • Busslinger M, Urbânek P. The role of BSAP (Pax-5) in B-cell development. Curr Opin Genet Dev. 5:1995;595-601.
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 595-601
    • Busslinger, M.1    Urbânek, P.2
  • 51
    • 0027997502 scopus 로고
    • Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
    • Urbanek P, Wang Z-Q, Fetka I, Wagner EF, Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell. 79:1994;901-912.
    • (1994) Cell , vol.79 , pp. 901-912
    • Urbanek, P.1    Wang Z-Q2    Fetka, I.3    Wagner, E.F.4    Busslinger, M.5
  • 52
    • 0031038031 scopus 로고    scopus 로고
    • Essential functions of Pax5 (BSAP) in pro-B cell development: Difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus
    • null mice. It reveals a marked difference in the requirement for Pax-5 between fetal liver, and adult, B cell development. It is made even more interesting by the finding that the more severe defect that occurs in fetal B cells is due to an influence of the fetal microenvironment.
    • null mice. It reveals a marked difference in the requirement for Pax-5 between fetal liver, and adult, B cell development. It is made even more interesting by the finding that the more severe defect that occurs in fetal B cells is due to an influence of the fetal microenvironment.
    • (1997) Genes Dev , vol.11 , pp. 476-491
    • Nutt, S.L.1    Urbanek2    Rolink, A.3    Busslinger, M.4
  • 53
    • 0028196601 scopus 로고
    • The B cell-specific transcription factor BSAP regulates B cell proliferation
    • Wakatsuki Y, Neurath MF, Max EE, Strober W. The B cell-specific transcription factor BSAP regulates B cell proliferation. J Exp Med. 179:1994;10099-10108.
    • (1994) J Exp Med , vol.179 , pp. 10099-10108
    • Wakatsuki, Y.1    Neurath, M.F.2    Max, E.E.3    Strober, W.4
  • 54
    • 0031110468 scopus 로고    scopus 로고
    • Overexpression of B cell-specific activator protein (BSAP/Pax-5) in a late B cell is sufficient suppress differentiation to an Ig high producer cell with plasma cell phenotype
    • Usui T, Wakatsuki Y, Matsunaga Y, Kaneko S, Kosek H, Kita T. Overexpression of B cell-specific activator protein (BSAP/Pax-5) in a late B cell is sufficient suppress differentiation to an Ig high producer cell with plasma cell phenotype. J Immunol. 158:1997;3197-3204.
    • (1997) J Immunol , vol.158 , pp. 3197-3204
    • Usui, T.1    Wakatsuki, Y.2    Matsunaga, Y.3    Kaneko, S.4    Kosek, H.5    Kita, T.6
  • 55
    • 0027262608 scopus 로고
    • Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival
    • Corcoran LM, Karvelas M, Nossal GJV, Ye Z-S, Jacks T, Baltimore D. Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival. Genes Dev. 7:1993;570-582.
    • (1993) Genes Dev , vol.7 , pp. 570-582
    • Corcoran, L.M.1    Karvelas, M.2    Nossal, G.J.V.3    Ye Z-S4    Jacks, T.5    Baltimore, D.6
  • 56
    • 0029041509 scopus 로고
    • Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B
    • Luo Y, Roeder R. Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol Cell Biol. 15:1995;4115-4124.
    • (1995) Mol Cell Biol , vol.15 , pp. 4115-4124
    • Luo, Y.1    Roeder, R.2
  • 57
    • 0028842156 scopus 로고
    • OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins
    • Strubin M, Newell JW, Matthias P. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell. 80:1995;497-506.
    • (1995) Cell , vol.80 , pp. 497-506
    • Strubin, M.1    Newell, J.W.2    Matthias, P.3
  • 58
    • 0029935909 scopus 로고    scopus 로고
    • The B cell coactivator Bob 1 shows DNA sequence dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation
    • Gstaiger M, Georgiev O, van Leeuwen H, van der Vliet P, Schaffner W. The B cell coactivator Bob 1 shows DNA sequence dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation. EMBO J. 15:1996;2781-2790.
    • (1996) EMBO J , vol.15 , pp. 2781-2790
    • Gstaiger, M.1    Georgiev, O.2    Van Leeuwen, H.3    Van Der Vliet, P.4    Schaffner, W.5
  • 59
    • 0029967024 scopus 로고    scopus 로고
    • B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation
    • of special interest. This paper reports that inactivation of the Oca-B gene allows normal B cell development, but results in severe problems in peripheral B cell function.
    • of special interest Schubart DB, Rolink A, Kosco-Vilbois MH, Botteri F, Matthias P. B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation. Nature. 383:1996;538-542 This paper reports that inactivation of the Oca-B gene allows normal B cell development, but results in severe problems in peripheral B cell function.
    • (1996) Nature , vol.383 , pp. 538-542
    • Schubart, D.B.1    Rolink, A.2    Kosco-Vilbois, M.H.3    Botteri, F.4    Matthias, P.5
  • 60
    • 23444459544 scopus 로고
    • Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells
    • Turner CA, Mack DH, Davis MM. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell. 77:1994;297-306.
    • (1994) Cell , vol.77 , pp. 297-306
    • Turner, C.A.1    Mack, D.H.2    Davis, M.M.3
  • 61
    • 0030950523 scopus 로고    scopus 로고
    • Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation
    • Lin Y, Wong K-K, Calame K. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science. 276:1997;596-599.
    • (1997) Science , vol.276 , pp. 596-599
    • Lin, Y.1    Wong K-K2    Calame, K.3
  • 62
    • 0031963751 scopus 로고    scopus 로고
    • Proinflammatory signalling: Last pieces in the NF-κB puzzle?
    • Baeuerle PA. Proinflammatory signalling: last pieces in the NF-κB puzzle? Curr Biol. 8:1998;R19-R22.
    • (1998) Curr Biol , vol.8
    • Baeuerle, P.A.1
  • 63
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • DeFranco AL. The complexity of signaling pathways activated by the BCR. Curr Opin Immunol. 9:1997;296-308.
    • (1997) Curr Opin Immunol , vol.9 , pp. 296-308
    • Defranco, A.L.1
  • 64
    • 0029983731 scopus 로고    scopus 로고
    • The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis
    • Corcoran AE, Smart FM, Cowling RJ, Crompton T, Owen MJ, Venkitaraman AR. The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis. EMBO J. 15:1996;1924-1932.
    • (1996) EMBO J , vol.15 , pp. 1924-1932
    • Corcoran, A.E.1    Smart, F.M.2    Cowling, R.J.3    Crompton, T.4    Owen, M.J.5    Venkitaraman, A.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.