-
1
-
-
70349583511
-
Discovery, structure and biological activities of cyclotides
-
Daly, N.L., Rosengren, K.J., and Craik, D.J. (2009) Discovery, structure and biological activities of cyclotides. Adv. Drug Deliv. Rev. 61(11), 918–930.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, Issue.11
, pp. 918-930
-
-
Daly, N.L.1
Rosengren, K.J.2
Craik, D.J.3
-
2
-
-
4444291734
-
Activation of apoptosis in vivo by a hydrocar-bon-stapled BH3 helix
-
Walensky, L.D., Kung, A.L., Escher, I., Malia, T.J., Barbuto, S., Wright, R.D.,Wagner, G., Verdine, G.L., and Korsmeyer, S.J. (2004) Activation of apoptosis in vivo by a hydrocar-bon-stapled BH3 helix. Science 305, 1466–1470.
-
(2004)
Science
, vol.305
, pp. 1466-1470
-
-
Walensky, L.D.1
Kung, A.L.2
Escher, I.3
Malia, T.J.4
Barbuto, S.5
Wright, R.D.6
Wagner, G.7
Verdine, G.L.8
Korsmeyer, S.J.9
-
3
-
-
35248880092
-
TAT transduction: The molecular mechanism and therapeutic prospects
-
Gump, J.M., and Dowdy, S.F. (2007) TAT transduction: the molecular mechanism and therapeutic prospects. Trends Mol. Med. 13, 443–448.
-
(2007)
Trends Mol. Med.
, vol.13
, pp. 443-448
-
-
Gump, J.M.1
Dowdy, S.F.2
-
4
-
-
34548145634
-
Cell-penetrating peptides in drug development: Enabling intracellular targets
-
Chen, L., and Harrison, S.D. (2007) Cell-penetrating peptides in drug development: enabling intracellular targets. Biochem. Soc. Trans. 35, 821–825.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 821-825
-
-
Chen, L.1
Harrison, S.D.2
-
5
-
-
38949095271
-
Protein and peptide transduction, twenty years later a happy birthday
-
Prochiantz, A. (2008) Protein and peptide transduction, twenty years later a happy birthday. Adv. Drug Deliv. Rev. 60, 448–451.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 448-451
-
-
Prochiantz, A.1
-
6
-
-
38949192863
-
Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers
-
Torchilin, V.P. (2008) Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers. Adv. Drug Deliv. Rev. 60, 548–558.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 548-558
-
-
Torchilin, V.P.1
-
7
-
-
39149103400
-
The design of guanidinium-rich transporters and their internalization mechanisms
-
Wender, P.A., Galliher, W.C., Goun, E.A., Jones, L.R., and Pillow, T.H. (2008) The design of guanidinium-rich transporters and their internalization mechanisms. Adv. Drug Deliv. Rev. 60, 452–472.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 452-472
-
-
Wender, P.A.1
Galliher, W.C.2
Goun, E.A.3
Jones, L.R.4
Pillow, T.H.5
-
8
-
-
0023990358
-
Tat protein from human immunodeficiency virus forms a metal-linked dimer
-
Frankel, A.D., Bredt, D.S., and Pabo, C.O. (1988) Tat protein from human immunodeficiency virus forms a metal-linked dimer. Science 240, 70–73.
-
(1988)
Science
, vol.240
, pp. 70-73
-
-
Frankel, A.D.1
Bredt, D.S.2
Pabo, C.O.3
-
9
-
-
0026093069
-
Antennapedia homeobox peptide regulates neural morphogenesis
-
Joliot, A., Pernelle, C., Deagostini-Bazin, H., and Prochiantz, A. (1991) Antennapedia homeobox peptide regulates neural morphogenesis. Proc. Natl. Acad. Sci. U.S.A. 88, 1864–1868.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 1864-1868
-
-
Joliot, A.1
Pernelle, C.2
Deagostini-Bazin, H.3
Prochiantz, A.4
-
10
-
-
0028054797
-
Tat-mediated delivery of heterologous proteins into cells
-
Fawell, S., Seery, J., Daikh, Y., Moore, C., Chen, L.L., Pepinsky, B., and Barsoum, J. (1994) Tat-mediated delivery of heterologous proteins into cells. Proc. Natl. Acad. Sci. U.S.A. 91, 664–668.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 664-668
-
-
Fawell, S.1
Seery, J.2
Daikh, Y.3
Moore, C.4
Chen, L.L.5
Pepinsky, B.6
Barsoum, J.7
-
11
-
-
0028239908
-
The third helix of the antennapedia homeodomain translocates through biological membranes
-
Derossi, D., Joliot, A.H., Chassaing, G., and Prochiantz, A. (1994) The third helix of the antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 269, 10444–10450.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
12
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives, E., Brodin, P., and Lebleu, B. (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010–16017.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
13
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze, S.R., Ho, A., Vocero-Akbani, A., and Dowdy, S.F. (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569–1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
14
-
-
0035937124
-
Arginine-rich peptides
-
Futaki, S., Suzuki, T., Ohashi, W., Yagami, T., Tanaka, S., Ueda, K., and Sugiura, Y. (2001) Arginine-rich peptides: an abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J. Biol. Chem. 276, 5836–5840.
-
(2001)
An Abundant Source of Membrane-Permeable Peptides Having Potential as Carriers for Intracellular Protein Delivery. J. Biol. Chem.
, vol.276
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
Yagami, T.4
Tanaka, S.5
Ueda, K.6
Sugiura, Y.7
-
15
-
-
27644561216
-
Characterisation of cell-penetrating peptide-mediated peptide delivery
-
Jones, S.W., Christison, R., Bundell, K., Voyce, C.J., Brockbank, S.M.V., Newham, P., and Lindsay, M.A. (2005) Characterisation of cell-penetrating peptide-mediated peptide delivery. Br. J. Pharmacol. 145, 1093–1102.
-
(2005)
Br. J. Pharmacol.
, vol.145
, pp. 1093-1102
-
-
Jones, S.W.1
Christison, R.2
Bundell, K.3
Voyce, C.J.4
Brockbank, S.M.V.5
Newham, P.6
Lindsay, M.A.7
-
17
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender, P.A., Mitchell, D.J., Pattabiraman, K., Pelkey, E.T., Steinman, L., and Rothbard, J.B. (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl. Acad. Sci. U.S.A. 97, 13003–13008.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
18
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparin sulfate receptors
-
Richard, J.P., Melikov, K., Brooks, H., Prevot, P., Lebleu, B., and Chernomordik, L.V. (2005) Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparin sulfate receptors. J. Biol. Chem. 280, 15300–15306.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
19
-
-
0348010364
-
Cytoplasmic and nuclear delivery of a TAT-derived peptide and a b-peptide after endocytic uptake into HeLa cells
-
Potocky, T.B., Menon, A.K., and Gellman, S.H. (2003) Cytoplasmic and nuclear delivery of a TAT-derived peptide and a b-peptide after endocytic uptake into HeLa cells. J. Biol. Chem. 278, 50188–50194.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50188-50194
-
-
Potocky, T.B.1
Menon, A.K.2
Gellman, S.H.3
-
20
-
-
0141446039
-
Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins
-
Fittipaldi, A., Ferrari, A., Zoppe, M., Arcangeli, C., Pellegrini, V., Beltram, F., and Giacca, M. (2003) Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins. J. Biol. Chem. 278, 34141–34149.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34141-34149
-
-
Fittipaldi, A.1
Ferrari, A.2
Zoppe, M.3
Arcangeli, C.4
Pellegrini, V.5
Beltram, F.6
Giacca, M.7
-
21
-
-
0041816277
-
Antennapedia and HIV transactivator of transcription (TAT) “protein transduction domains” promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans
-
Console, S., Marty, C., Garcia-Echeverria, C., Schwendener, R., and Ballmer-Hofer, K. (2003) Antennapedia and HIV transactivator of transcription (TAT) “protein transduction domains” promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. J. Biol. Chem. 278, 35109–35114.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35109-35114
-
-
Console, S.1
Marty, C.2
Garcia-Echeverria, C.3
Schwendener, R.4
Ballmer-Hofer, K.5
-
22
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparin sulfate receptors
-
Richard, J.P., Melikov, K., Brooks, H., Prevot, P., Lebleu, B., and Chernomordik, L.V. (2005) Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparin sulfate receptors. J. Biol. Chem. 280, 15300–15306.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
23
-
-
0037119348
-
Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate
-
Mai, J.C., Shen, H., Watkins, S.C., Cheng, T., and Robbins, P.D. (2002) Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate. J. Biol. Chem. 277, 30208–30218.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30208-30218
-
-
Mai, J.C.1
Shen, H.2
Watkins, S.C.3
Cheng, T.4
Robbins, P.D.5
-
24
-
-
0035793619
-
Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans
-
Tyagi, M., Rusnati, M., Presta, M., and Giacca, M. (2001) Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans. J. Biol. Chem. 276, 3254–3261.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3254-3261
-
-
Tyagi, M.1
Rusnati, M.2
Presta, M.3
Giacca, M.4
-
25
-
-
0037063996
-
Nuclear targeting of macromolecular polyanions by an HIV-Tat derived peptide
-
Sandgren, S., Cheng, F., and Belting, M. (2002) Nuclear targeting of macromolecular polyanions by an HIV-Tat derived peptide: role for cell-surface proteoglycans. J. Biol. Chem. 277, 38877–38883.
-
(2002)
Role for Cell-Surface Proteoglycans. J. Biol. Chem.
, vol.277
, pp. 38877-38883
-
-
Sandgren, S.1
Cheng, F.2
Belting, M.3
-
26
-
-
1842529513
-
A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides
-
Fischer, R., Kohler, K., Fotin-Mleczek, M., and Brock, R. (2004) A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides. J. Biol. Chem. 279, 12625–12635.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12625-12635
-
-
Fischer, R.1
Kohler, K.2
Fotin-Mleczek, M.3
Brock, R.4
-
27
-
-
3042694907
-
D-JNKI1, A cell-penetrating c-jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia
-
Hirt, L., Badaut, J., Thevenet, J., Granziera, C., Regli, L., Maurer, F., Bonny, C.,and Bogousslavsky, J. (2004) D-JNKI1, A cell-penetrating c-jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia. Stroke 35, 1738–1743.
-
(2004)
Stroke
, vol.35
, pp. 1738-1743
-
-
Hirt, L.1
Badaut, J.2
Thevenet, J.3
Granziera, C.4
Regli, L.5
Maurer, F.6
Bonny, C.7
Bogousslavsky, J.8
-
28
-
-
85139051620
-
KAI-1678, a novel inhibitor of protein kinase C epsilon, attenuates hyperalgesia and allodynia in three neuropathic pain models in rodents
-
Miao, F. J.-P., Mohammad, H.K., Velazquez, K.T., Harrison, S.D., and Sweitzer, S.M. (2008) KAI-1678, a novel inhibitor of protein kinase C epsilon, attenuates hyperalgesia and allodynia in three neuropathic pain models in rodents. Soc. Neurosci. (Abs.) 774.10.
-
(2008)
Soc. Neurosci. (Abs.)
, vol.774
, pp. 10
-
-
Miao, F.J.-P.1
Mohammad, H.K.2
Velazquez, K.T.3
Harrison, S.D.4
Sweitzer, S.M.5
-
29
-
-
85139048112
-
KAI-1678, a novel inhibitor of protein kinase C epsilon, attenuates mechanical hyperalgesia in rodent models of acute nociceptive, inflammatory and post-surgical pain. Soc
-
Velazquez, K.T., Miao, F.J.P., Mohammad, H.K., Ogden, C.J., Harrison, S.D., and Sweitzer, S.M. (2008) KAI-1678, a novel inhibitor of protein kinase C epsilon, attenuates mechanical hyperalgesia in rodent models of acute nociceptive, inflammatory and post-surgical pain. Soc. Neurosci. (Abs.) 468.16.
-
(2008)
Neurosci. (Abs.)
, vol.468
, pp. 16
-
-
Velazquez, K.T.1
Miao, F.J.P.2
Mohammad, H.K.3
Ogden, C.J.4
Harrison, S.D.5
Sweitzer, S.M.6
-
30
-
-
0242442127
-
Inhibition of d-protein kinase C protects against reperfusion injury of the ischemic heart in vivo
-
Inagaki, K., Chen, L., Ikeno, F., Lee, F.H., Imahashi, K., Bouley, D.M., Rezaee, M., Yock, P.G., Murphy, E., Mochly-Rosen, D. (2003) Inhibition of d-protein kinase C protects against reperfusion injury of the ischemic heart in vivo. Circulation 108, 2304–2307.
-
(2003)
Circulation
, vol.108
, pp. 2304-2307
-
-
Inagaki, K.1
Chen, L.2
Ikeno, F.3
Lee, F.H.4
Imahashi, K.5
Bouley, D.M.6
Rezaee, M.7
Yock, P.G.8
Murphy, E.9
Mochly-Rosen, D.10
-
31
-
-
85138994932
-
-
Sho, E., Dong, J., Jin, Z., Begley, R., Chen, L., Harrison, S.D., and Mendel, D.B. (2008) Protein kinase C-d inhibitor protects against ischemic stroke by inhibiting cellular injury and inflammation and promoting astrocyte proliferation. Int. Stroke Conf. Abstr. 39, P422, 671–672.
-
Sho, E., Dong, J., Jin, Z., Begley, R., Chen, L., Harrison, S.D., and Mendel, D.B. (2008) Protein kinase C-d inhibitor protects against ischemic stroke by inhibiting cellular injury and inflammation and promoting astrocyte proliferation. Int. Stroke Conf. Abstr. 39, P422, 671–672.
-
-
-
-
32
-
-
39449092458
-
Direct inhibition of d-protein kinase C enzyme to limit total infarct size in acute myocardial infarction (DELTA MI) investigators. (2008) Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction
-
Direct inhibition of d-protein kinase C enzyme to limit total infarct size in acute myocardial infarction (DELTA MI) investigators. (2008) Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. Circulation 117, 886–896.
-
Circulation
, vol.117
, pp. 886-896
-
-
-
33
-
-
57349138758
-
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
-
Liu, X. J., Gingrich, J.R., Vargas-Caballero, M., Dong, Y.N., Sengar, A., Beggs, S., Wang, S.-H., Ding, H.K., Frankland, P.W., and Salter, M.W. (2008) Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex. Nat. Med. 14, 1325–1332.
-
(2008)
Nat. Med.
, vol.14
, pp. 1325-1332
-
-
Liu, X.J.1
Gingrich, J.R.2
Vargas-Caballero, M.3
Dong, Y.N.4
Sengar, A.5
Beggs, S.6
Wang, S.-H.7
Ding, H.K.8
Frankland, P.W.9
Salter, M.W.10
-
34
-
-
85139064821
-
Inhibition of protein kinase C epsilon translocation reduces allodynia and hyperalgesia in a rodent model of neuropathic pain
-
Abs.) 185.2
-
Sweitzer, S.M., Mohammad, H.K., Velasquez, K.T., and Harrison, S.D. (2007) Inhibition of protein kinase C epsilon translocation reduces allodynia and hyperalgesia in a rodent model of neuropathic pain. Soc. Neurosci. (Abs.) 185.2.
-
(2007)
Soc. Neurosci.
-
-
Sweitzer, S.M.1
Mohammad, H.K.2
Velasquez, K.T.3
Harrison, S.D.4
-
35
-
-
85139066891
-
A small peptide inhibitor of gPKC translocation attenuates allodynia and hyperalgesia in a rodent model of neuropathic pain
-
Abs.) 185.4
-
Velazquez, K.T., Mohammad, H.K., Harrison, S.D., and Sweitzer, S.M. (2007) A small peptide inhibitor of gPKC translocation attenuates allodynia and hyperalgesia in a rodent model of neuropathic pain. Soc. Neurosci. (Abs.) 185.4.
-
(2007)
Soc. Neurosci.
-
-
Velazquez, K.T.1
Mohammad, H.K.2
Harrison, S.D.3
Sweitzer, S.M.4
-
36
-
-
0033678653
-
Conjugation of arginine oligomers to cyclosporine A facilitates topical delivery and inhibition of inflammation
-
Rothbard, J.B., Garlington, S., Lin, Q., Kirschberg, T., Kreider, E., McGrane, P.L., Wender, P.A., and Khavari, P.A. (2000) Conjugation of arginine oligomers to cyclosporine A facilitates topical delivery and inhibition of inflammation. Nat. Med. 6, 1253–1257.
-
(2000)
Nat. Med.
, vol.6
, pp. 1253-1257
-
-
Rothbard, J.B.1
Garlington, S.2
Lin, Q.3
Kirschberg, T.4
Kreider, E.5
McGrane, P.L.6
Wender, P.A.7
Khavari, P.A.8
-
37
-
-
2442546710
-
Biodistribution of intracel-lularly-acting peptides conjugated reversibly to Tat
-
Begley, R., Liron, T., Baryza, J., and Mochly-Rosen, D. (2004) Biodistribution of intracel-lularly-acting peptides conjugated reversibly to Tat. Biochem. Biophys. Res. Commun. 318, 949–954.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 949-954
-
-
Begley, R.1
Liron, T.2
Baryza, J.3
Mochly-Rosen, D.4
-
38
-
-
33749425409
-
TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice
-
Toro, A., and Grunebaum, E. (2006) TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice. J. Clin. Invest. 116, 2717–2726.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2717-2726
-
-
Toro, A.1
Grunebaum, E.2
-
39
-
-
0037154270
-
Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides
-
Covic, L., Gresser, A.L., Talavera, J., Swift, S., and Kuliopulos, A. (2002) Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides. Proc. Natl. Acad. Sci. U S.A. 99, 643–648.
-
(2002)
Proc. Natl. Acad. Sci. U S.A.
, vol.99
, pp. 643-648
-
-
Covic, L.1
Gresser, A.L.2
Talavera, J.3
Swift, S.4
Kuliopulos, A.5
-
40
-
-
0035949580
-
Opposing cardioprotective actions and parallel hypertro-phic effects of dPKC and ePKC
-
Chen, L., Hahn, H., Wu, G., Chen, C.-H., Liron, T., Schechtman, D., Cavallaro, G., Banci, L., Guo, Y., Bolli, R., Dorn II, G.W., and Mochly-Rosen, D. (2001) Opposing cardioprotective actions and parallel hypertro-phic effects of dPKC and ePKC. Proc. Natl. Acad. Sci. U S.A. 98, 11114–11119.
-
(2001)
Proc. Natl. Acad. Sci. U S.A.
, vol.98
, pp. 11114-11119
-
-
Chen, L.1
Hahn, H.2
Wu, G.3
Chen, C.-H.4
Liron, T.5
Schechtman, D.6
Cavallaro, G.7
Banci, L.8
Guo, Y.9
Bolli, R.10
Dorn, G.W.11
Mochly-Rosen, D.12
-
41
-
-
0037168589
-
Protection against ischemic brain injury by protein therapeutics
-
Asoh, S., Ohsawa, I., Mori, T., Katsura, K., Hiraide, T., Katayama, Y., Kimura, M., Ozaki, D., Yamagata, K., and Ohta, S. (2002) Protection against ischemic brain injury by protein therapeutics. Proc. Natl. Acad. Sci. U.S.A. 99, 17107–17112.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 17107-17112
-
-
Asoh, S.1
Ohsawa, I.2
Mori, T.3
Katsura, K.4
Hiraide, T.5
Katayama, Y.6
Kimura, M.7
Ozaki, D.8
Yamagata, K.9
Ohta, S.10
-
42
-
-
0036663014
-
In vivo delivery of a Bcl-xL fusion protein containing TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis
-
Cao, G., Pei, W., Ge, H., Liang, Q., Luo, Y., Sharp, F.R., Lu, A., Ran, R., Graham, S.H., and Chen, J. (2002) In vivo delivery of a Bcl-xL fusion protein containing TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis. J. Neurosci. 22, 5423–5431.
-
(2002)
J. Neurosci.
, vol.22
, pp. 5423-5431
-
-
Cao, G.1
Pei, W.2
Ge, H.3
Liang, Q.4
Luo, Y.5
Sharp, F.R.6
Lu, A.7
Ran, R.8
Graham, S.H.9
Chen, J.10
-
43
-
-
3843146318
-
Protein kinase C d mediates cerebral reperfusion injury in vivo
-
Bright, R., Raval, A.P., Dembner, J.M., Perez-Pinzon, M.A., Steinberg, G.K., Yenari, M.A., and Mochly-Rosen, D. (2004) Protein kinase C d mediates cerebral reperfusion injury in vivo. J. Neurosci. 24, 6880–6888.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6880-6888
-
-
Bright, R.1
Raval, A.P.2
Dembner, J.M.3
Perez-Pinzon, M.A.4
Steinberg, G.K.5
Yenari, M.A.6
Mochly-Rosen, D.7
-
44
-
-
5644276383
-
Delivery of bioactive molecules into the cell: The Trojan horse approach
-
Dietz, G.P.H., and Bohr, M. (2004) Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol. Cell. Neurosci. 27(2), 85–131.
-
(2004)
Mol. Cell. Neurosci.
, vol.27
, Issue.2
, pp. 85-131
-
-
Dietz, G.P.H.1
Bohr, M.2
-
45
-
-
38349174536
-
On the biomedical promise of cell penetrating peptides: Limits versus prospects
-
Foerg, C., and Merkle, HP. (2008) On the biomedical promise of cell penetrating peptides: limits versus prospects. J. Pharm. Sci. 97, 144–162
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 144-162
-
-
Foerg, C.1
Merkle, H.P.2
-
46
-
-
0028938152
-
Localization of protein kinases by anchoring proteins: A theme in signal transduction
-
Mochly-Rosen, D. (1995) Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268, 247–251.
-
(1995)
Science
, vol.268
, pp. 247-251
-
-
Mochly-Rosen, D.1
-
47
-
-
0031964645
-
Anchoring proteins for protein kinase C: A means for isozyme selectivity
-
Mochly-Rosen, D., and Gordon, A.S. (1998) Anchoring proteins for protein kinase C: a means for isozyme selectivity. FASEB J. 12, 35–42.
-
(1998)
FASEB J
, vol.12
, pp. 35-42
-
-
Mochly-Rosen, D.1
Gordon, A.S.2
-
49
-
-
0041932511
-
Additive protection of the ischemic heart ex vivo by combined treatment with d-protein kinase C inhibitor and e-protein kinase C activator
-
Inagaki, K., Hahn, H.S., Dorn II, G.W., and Mochly-Rosen, D. (2003) Additive protection of the ischemic heart ex vivo by combined treatment with d-protein kinase C inhibitor and e-protein kinase C activator. Circulation 108, 869–875.
-
(2003)
Circulation
, vol.108
, pp. 869-875
-
-
Inagaki, K.1
Hahn, H.S.2
Dorn, G.W.3
Mochly-Rosen, D.4
-
50
-
-
63349107047
-
The divergent roles of protein kinase C epsilon and delta in simulated ischaemia-reperfusion injury in human myocardium
-
Sivaraman, V., Hausenloy, D.J., Kolvekar, S., Hayward, M., Lawrence, D., Yap, J., Di Salvo, C., and Yellon, D.M. (2009) The divergent roles of protein kinase C epsilon and delta in simulated ischaemia-reperfusion injury in human myocardium. J. Mol Cell. Cardiol. 46, 758–764.
-
(2009)
J. Mol Cell. Cardiol.
, vol.46
, pp. 758-764
-
-
Sivaraman, V.1
Hausenloy, D.J.2
Kolvekar, S.3
Hayward, M.4
Lawrence, D.5
Yap, J.6
Di Salvo, C.7
Yellon, D.M.8
-
51
-
-
85139054730
-
Protein kinase C-d inhibitor protects against acute myocardial infarction by intravenous administration in different periods of cardiac ischemia-reperfusion
-
Sho, E., Dong, J., Jin, Z., Lee, Y.S., Harrison, S., and Mendel, D. (2008) Protein kinase C-d inhibitor protects against acute myocardial infarction by intravenous administration in different periods of cardiac ischemia-reperfusion. J. Am. Coll. Cardiol. Suppl. A 51(10), 1003–1086,
-
(2008)
J. Am. Coll. Cardiol. Suppl. A
, vol.51
, Issue.10
, pp. 1003-1086
-
-
Sho, E.1
Dong, J.2
Jin, Z.3
Lee, Y.S.4
Harrison, S.5
Mendel, D.6
-
52
-
-
34250162152
-
Effect of cell-based intracellular delivery of transcription factor GATA4 on ischemic cardiomyopathy
-
Bian, J., Popovic, Z.B., Benejam, C., Kiedrowski, M., Rodriguez, L.L., and Penn, M.S. (2007) Effect of cell-based intracellular delivery of transcription factor GATA4 on ischemic cardiomyopathy. Circ. Res. 100, 1626–1633.
-
(2007)
Circ. Res.
, vol.100
, pp. 1626-1633
-
-
Bian, J.1
Popovic, Z.B.2
Benejam, C.3
Kiedrowski, M.4
Rodriguez, L.L.5
Penn, M.S.6
-
53
-
-
33744544769
-
Toward better pain control
-
Basbaum, A.I., and Julius, D. (2006) Toward better pain control. Sci. Am. 294(6), 61–67.
-
(2006)
Sci. Am.
, vol.294
, Issue.6
, pp. 61-67
-
-
Basbaum, A.I.1
Julius, D.2
-
54
-
-
0033526651
-
Neuropathic pain: Aetiology, symptoms, mechanisms, and management
-
Woolf, C.J., and Mannion, R.J. (1999) Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet 353, 1959–1964.
-
(1999)
Lancet
, vol.353
, pp. 1959-1964
-
-
Woolf, C.J.1
Mannion, R.J.2
-
55
-
-
2142717361
-
Protein kinase C e and g: Involvement in formalin-induced nociception in neonatal rats
-
Sweitzer, S. M., Wong, S.M.E., Peters, M.C., Mochly-Rosen, D., Yeomans, D.C., and Kendig, J.J. (2004) Protein kinase C e and g: involvement in formalin-induced nociception in neonatal rats. J. Pharmacol. Exp. Ther. 309, 616–625.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.309
, pp. 616-625
-
-
Sweitzer, S.M.1
Wong, S.M.E.2
Peters, M.C.3
Mochly-Rosen, D.4
Yeomans, D.C.5
Kendig, J.J.6
-
56
-
-
23444452687
-
Ethanol withdrawal-associated allodynia and hyperalgesia: Age-dependent regulation by protein kinase Ce and g isozymes
-
Shumilla, J.A., Liron, T., Mochly-Rosen, D., Kendig, J.J., and Sweitzer, S. M. (2005) Ethanol withdrawal-associated allodynia and hyperalgesia: age-dependent regulation by protein kinase Ce and g isozymes. J. Pain 6, 535–549.
-
(2005)
J. Pain
, vol.6
, pp. 535-549
-
-
Shumilla, J.A.1
Liron, T.2
Mochly-Rosen, D.3
Kendig, J.J.4
Sweitzer, S.M.5
-
57
-
-
33845681648
-
Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice
-
Smith, F.L., Gabra, B.H., Smith, P.A., Redwood, M.C., and Dewey, W.L. (2007) Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice. Pain 127, 129–139.
-
(2007)
Pain
, vol.127
, pp. 129-139
-
-
Smith, F.L.1
Gabra, B.H.2
Smith, P.A.3
Redwood, M.C.4
Dewey, W.L.5
-
58
-
-
2142669035
-
Exaggerated nociceptive responses on morphine withdrawal: Roles of protein kinase C e and g
-
Sweitzer, S.M., Wong, S.M.E., Tjolsen, A., Allen, C.P., Mochly-Rosen, D., and Kendig, J.J. (2004) Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C e and g. Pain 110, 281–289.
-
(2004)
Pain
, vol.110
, pp. 281-289
-
-
Sweitzer, S.M.1
Wong, S.M.E.2
Tjolsen, A.3
Allen, C.P.4
Mochly-Rosen, D.5
Kendig, J.J.6
-
59
-
-
21844477537
-
Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells
-
Michiue, H., Tomizawa, K., Matsushita, M., Tamiya, T., Lu, Y.F., Ichikawa, T., Date, I., and Matsui, H. (2005) Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells. FEBS Lett. 579, 3965–3969.
-
(2005)
FEBS Lett
, vol.579
, pp. 3965-3969
-
-
Michiue, H.1
Tomizawa, K.2
Matsushita, M.3
Tamiya, T.4
Lu, Y.F.5
Ichikawa, T.6
Date, I.7
Matsui, H.8
-
60
-
-
19344365470
-
Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide
-
Snyder, E.L., Meade, B.R., Saenz, C.C., and Dowdy, S.F. (2004) Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide. PLoS Biol. 2, 186–193.
-
(2004)
Plos Biol
, vol.2
, pp. 186-193
-
-
Snyder, E.L.1
Meade, B.R.2
Saenz, C.C.3
Dowdy, S.F.4
-
61
-
-
0033199874
-
Protein kinase C lies on the signaling pathway for vascular endothelial growth factor-mediated tumor development and angiogenesis
-
Yoshiji, H., Kuriyama, S., Ways, D.K., Yoshii, J., Miyamoto, Y., Kawata, M., Ikenaka, Y., Tsujinoue, H., Nakatani, T., Shibuya, M., and Fukui, H. (1999) Protein kinase C lies on the signaling pathway for vascular endothelial growth factor-mediated tumor development and angiogenesis. Cancer Res. 59, 4413–4418.
-
(1999)
Cancer Res
, vol.59
, pp. 4413-4418
-
-
Yoshiji, H.1
Kuriyama, S.2
Ways, D.K.3
Yoshii, J.4
Miyamoto, Y.5
Kawata, M.6
Ikenaka, Y.7
Tsujinoue, H.8
Nakatani, T.9
Shibuya, M.10
Fukui, H.11
-
62
-
-
53049108851
-
Centrosomal PKCbII and pericentrin are critical for human prostate cancer growth and angiogenesis
-
Kim, J., Choi, Y.-L., Vallentin, A., Hunrichs, B.S., Hellerstein, M.K., Peehl, D.M., and Mochly-Rosen, D. (2008) Centrosomal PKCbII and pericentrin are critical for human prostate cancer growth and angiogenesis. Cancer Res. 68(16), 6831–6839.
-
(2008)
Cancer Res
, vol.68
, Issue.16
, pp. 6831-6839
-
-
Kim, J.1
Choi, Y.-L.2
Vallentin, A.3
Hunrichs, B.S.4
Hellerstein, M.K.5
Peehl, D.M.6
Mochly-Rosen, D.7
-
63
-
-
33751004418
-
Improved therapeutic efficacy of doxorubicin through conjugation with a novel peptide drug delivery technology (Vectocell)
-
Meyer-Losic, F., Quinonero, J., Dubois, V., Alluis, B., Dechambre, M., Michel, M., Callier, F., Fernandez, A.-M., Trouet, A., and Kearsey, J. (2006) Improved therapeutic efficacy of doxorubicin through conjugation with a novel peptide drug delivery technology (Vectocell). J. Med. Chem. 49(23), 6908–6916.
-
(2006)
J. Med. Chem.
, vol.49
, Issue.23
, pp. 6908-6916
-
-
Meyer-Losic, F.1
Quinonero, J.2
Dubois, V.3
Alluis, B.4
Dechambre, M.5
Michel, M.6
Callier, F.7
Fernandez, A.-M.8
Trouet, A.9
Kearsey, J.10
-
64
-
-
42249108725
-
DTS-108, a novel peptidic prodrug of SN38: In vivo efficacy and toxicokinetic studies
-
Meyer-Losic, F., Nicolazzi, C., Quinonero, J., Ribes, F., Michel, M., Dubois, V., de Coupade, C., Boukaissi, M., Chene, A.-S., Tranchant, I., Arranz, V., Zoubaa, I., Fruchart, J.-S., Ravel, D., and Kearsey, J. (2008) DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies. Clin. Cancer Res. 14(7), 2145–2153.
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.7
, pp. 2145-2153
-
-
Meyer-Losic, F.1
Nicolazzi, C.2
Quinonero, J.3
Ribes, F.4
Michel, M.5
Dubois, V.6
de Coupade, C.7
Boukaissi, M.8
Chene, A.-S.9
Tranchant, I.10
Arranz, V.11
Zoubaa, I.12
Fruchart, J.-S.13
Ravel, D.14
Kearsey, J.15
-
65
-
-
0035165348
-
Shifting the open artery hypothesis downstream: The quest for optimal reperfusion
-
Roe, M.T., Ohman, E.M., Maas, A.C.P., Christenson, R.H., Mahaffey, K.W., Granger, C.B., Harrington, R.A., Califf, R.M., and Krucoff, M.W. (2001) Shifting the open artery hypothesis downstream: the quest for optimal reperfusion. J. Am. Coll. Cardiol. 37, 9–18.
-
(2001)
J. Am. Coll. Cardiol.
, vol.37
, pp. 9-18
-
-
Roe, M.T.1
Ohman, E.M.2
Maas, A.C.P.3
Christenson, R.H.4
Mahaffey, K.W.5
Granger, C.B.6
Harrington, R.A.7
Califf, R.M.8
Krucoff, M.W.9
-
66
-
-
0141457877
-
A peptide inhibitor of c-jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss
-
Wang, J., Van De Water, T.R., Bonny, C., de Ribaupierre, F., Puel, J.L., and Zine, A. (2003) A peptide inhibitor of c-jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss. J. Neurosci. 23, 8596–8607.
-
(2003)
J. Neurosci.
, vol.23
, pp. 8596-8607
-
-
Wang, J.1
van De Water, T.R.2
Bonny, C.3
de Ribaupierre, F.4
Puel, J.L.5
Zine, A.6
-
67
-
-
33846032694
-
Topically applied botulinum toxin type A for the treatment of primary axillary hyperhidrosis: Results of a randomized, blinded vehicle-contolled study
-
Glogau, R.G. (2007) Topically applied botulinum toxin type A for the treatment of primary axillary hyperhidrosis: results of a randomized, blinded vehicle-contolled study. Dermatol. Surg. 33, S76–S80.
-
(2007)
Dermatol. Surg.
, vol.33
, pp. S76-S80
-
-
Glogau, R.G.1
-
68
-
-
59949098048
-
Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-b1-induced CTGF expression in keloid fibroblasts
-
Lopes, L.B., Furnish, E.J., Komalavilas, P., Flynn, C.R., Ashby, P., Hansen, A., Ly, D.P., Yang, G.P., Longaker, M.T., Panitch, A., and Brophy, C.M. (2009) Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-b1-induced CTGF expression in keloid fibroblasts. J. Invest. Dermatol. 129, 590–598.
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 590-598
-
-
Lopes, L.B.1
Furnish, E.J.2
Komalavilas, P.3
Flynn, C.R.4
Ashby, P.5
Hansen, A.6
Ly, D.P.7
Yang, G.P.8
Longaker, M.T.9
Panitch, A.10
Brophy, C.M.11
|