Selective inhibition of inducible nitric oxide synthase by derivatives of acetamidine

Medicinal Chemistry

Volumn 8, Issue 6, 2012, Pages 991-995

  MacCallini, Cristina ^a   Patruno, Antonia ^a   Ammazzalorso, Alessandra ^a   De Filippis, Barbara ^a   Fantacuzzi, Marialuigia ^a   Franceschelli, Sara ^a   Giampietro, Letizia ^a   Masella, Simona ^a   Tricca, Maria Luisa ^a   Amoroso, Rosa ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

Acetamidines; Nitric oxide; Nitric oxide synthase; Selective inducible NOS inhibitors

Indexed keywords

ACETAMIDINE DERIVATIVE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ETHYL 2 [4 (ETHANIMIDOYLAMINO)PHENYL]ACETATE HYDROBROMIDE; ETHYL 2 [4 (ETHANIMIDOYLAMINO)PIPERAZIN 1 YL]ACETATE HYDROBROMIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; N (1 PIPERIDYL)ACETAMIDINE HYDROBROMIDE; N (1 PIPERIDYLMETHYL)ACETAMIDINE HYDROBROMIDE; N (2 MORPHOLINOETHYL)ACETAMIDINE HYDROBROMIDE; N (2 PYRROLIDIN 1 YLETHYL)ACETAMIDINE HYDROBROMIDE; N (3 PHENYLPROPYL)ACETAMIDINE HYDROBROMIDE; N (3 PYRROLIDIN 1 YLPROPYL)ACETAMIDINE HYDROBROMIDE; N (TETRAHYDROFURAN 2 YLMETHYL)ACETAMIDINE HYDROBROMIDE; N [2 (1 PIPERIDYL)ETHYL]ACETAMIDINE HYDROBROMIDE; N [3 (2 METHYL 1 PIPERIDYL)PROPYL]ACETAMIDINE HYDROBROMIDE; N PHENETHYLACETAMIDINE HYDROBROMIDE; N PHENYLACETAMIDINE HYDROBROMIDE; N PYRROLIDIN 1 YLACETAMIDINE HYDROBROMIDE; NEURONAL NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; PRIORITY JOURNAL;

AMIDINES; ANIMALS; CATTLE; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS; INHIBITORY CONCENTRATION 50; LIGANDS; MICE; NITRIC OXIDE SYNTHASE TYPE II; SF9 CELLS; SPODOPTERA; SUBSTRATE SPECIFICITY;

EID: 84868031531     PISSN: 15734064     EISSN: 18756638     Source Type: Journal    
DOI: 10.2174/1573406411208060991     Document Type: Article

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