S-2-naphthylmethyl thioacetimidate hydrobromide: A new odorless reagent for the mild synthesis of substituted acetamidines

Tetrahedron Letters

Volumn 38, Issue 2, 1997, Pages 179-182

  Shearer, Barry G ^a   Oplinger, Jeffrey A ^a   Lee, Shuliang ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0031021264     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02268-X     Document Type: Article

References (5)

1. Patai, S. "The Chemistry of Amidines and Imidates"; Wiley: New York, 1975.
2. Pinner, A. "Die Imidoather and Ihre Derivative"; R. Oppenheim: Berlin, 1892.
3. For an example of a generalized synthesis of amidines from thioimidates see: Schnur, R.C. J. Org. Chem. 1979, 44, 3726.
4. Takido, Y.; Itabashi, K. Synthesis, 1987, 817.
5. Huynh-Dinh, T.; Sarfati, R.S.; Gouyette, C.; Igolen, J.; Bisagni, E.; Lhoste, J.-M.; Civier, A. J. Org. Chem. 1979, 44, 1028.