Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase

Journal of Medicinal Chemistry

Volumn 52, Issue 5, 2009, Pages 1481-1485

  Maccallim, Cristina ^a   Patruno, Antonia ^a   Bešker, Neva ^a   Alì, Jamila Isabella ^a   Ammazzalorso, Alessandra ^a   De Filippis, Barbara ^a   Franceschelli, Sara ^a   Giampietro, Letizia ^a   Pesce, Mirko ^a   Reale, Marcella ^a   Tricca, Maria L ^a   Re, Nazzareno ^a   Felaco, Mario ^a   Amoroso, Rosa ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDINE DERIVATIVE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; N (3 (AMINOMETHYL)BENZYL)ACETAMIDINE; N BENZYLACETAMIDINE; UNCLASSIFIED DRUG;

ARTICLE; EVALUATION; IN VITRO STUDY; MOLECULAR DOCKING; STRUCTURE ANALYSIS; SYNTHESIS;

AMIDINES; BENZYLAMINES; BINDING SITES; MODELS, MOLECULAR; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 64349090834     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800846u     Document Type: Article

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