메뉴 건너뛰기




Volumn 29, Issue 7, 2012, Pages 243-256

Structure, regulation and cellular functions of Rab geranylgeranyl transferase and its cellular partner Rab Escort Protein

Author keywords

Choroideremia; Rab Escort Protein; Rab geranylgeranyl transferase

Indexed keywords

HOLOENZYME; RAB ESCORT PROTEIN; RAB GERANYLGERANYL TRANSFERASE; RAB PROTEIN; UNCLASSIFIED DRUG;

EID: 84867962038     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.3109/09687688.2012.693211     Document Type: Article
Times cited : (11)

References (72)
  • 1
    • 0034898458 scopus 로고    scopus 로고
    • Organization of the Rab-GDI/CHM superfamily: The functional basis for choroideremia disease
    • DOI 10.1034/j.1600-0854.2001.20803.x
    • Alory C, Balch WE. 2001. Organization of the Rab-GDI/CHM superfamily: The functional basis for choroideremia disease. Traffic 2:532-543. (Pubitemid 32725398)
    • (2001) Traffic , vol.2 , Issue.8 , pp. 532-543
    • Alory, C.1    Balch, W.E.2
  • 2
    • 0141521588 scopus 로고    scopus 로고
    • Molecular evolution of the Rab-escortprotein/guanine-nucleotide- dissociation-inhibitor superfamily
    • Alory C, Balch WE. 2003. Molecular evolution of the Rab-escortprotein/ guanine-nucleotide-dissociation-inhibitor superfamily. Mol Biol Cell 14:3857-3867.
    • (2003) Mol Biol Cell , vol.14 , pp. 3857-3867
    • Alory, C.1    Balch, W.E.2
  • 3
    • 0029797447 scopus 로고    scopus 로고
    • Amino- and carboxy-terminal domains of the yeast rab escort protein are both required for binding of Ypt small G proteins
    • Bauer BE, Lorenzetti S, Miaczynska M, Bui DM, Schweyen RJ, Ragnini A. 1996. Amino-and carboxy-terminal domains of the yeast Rab escort protein are both required for binding of Ypt small G proteins. Mol Biol Cell 7:1521-1533. (Pubitemid 26339726)
    • (1996) Molecular Biology of the Cell , vol.7 , Issue.10 , pp. 1521-1533
    • Bauer, B.E.1    Lorenzetti, S.2    Miaczynska, M.3    Bui, D.M.4    Schweyen, R.J.5    Ragnini, A.6
  • 5
    • 0034062298 scopus 로고    scopus 로고
    • Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance
    • DOI 10.1046/j.1365-2958.2000.01782.x
    • Bialek-Wyrzykowska U, Bauer BE, Wagner W, Kohlwein SD, Schweyen RJ, Ragnini A. 2000. Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance. Mol Microbiol 35:1295-1311. (Pubitemid 30175507)
    • (2000) Molecular Microbiology , vol.35 , Issue.6 , pp. 1295-1311
    • Bialek-Wyrzykowska, U.1    Bauer, B.E.2    Wagner, W.3    Kohlwein, S.D.4    Schweyen, R.J.5    Ragnini, A.6
  • 6
    • 0031753250 scopus 로고    scopus 로고
    • A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1
    • Chen EJ, Frand AR, Chitouras E, Kaiser CA. 1998. A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1. Mol Cell Biol 18:7139-7146. (Pubitemid 28533033)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.12 , pp. 7139-7146
    • Chen, E.J.1    Frand, A.R.2    Chitouras, E.3    Kaiser, C.A.4
  • 7
    • 62749117198 scopus 로고    scopus 로고
    • Emerging roles for Rab family GTPases in human cancer
    • Chia WJ, Tang BL. 2009. Emerging roles for Rab family GTPases in human cancer. Biochim Biophys Acta 1795:110-116.
    • (2009) Biochim Biophys Acta , vol.1795 , pp. 110-116
    • Chia, W.J.1    Tang, B.L.2
  • 8
    • 84867961522 scopus 로고    scopus 로고
    • Choroideremia: A review of general findings and pathogenesis
    • Oct 21 in press
    • Coussa RG, Traboulsi EI. 2011. Choroideremia: A review of general findings and pathogenesis. Ophthalmic Genet Oct 21; in press.
    • (2011) Ophthalmic Genet
    • Coussa, R.G.1    Traboulsi, E.I.2
  • 12
    • 81255136935 scopus 로고    scopus 로고
    • Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with Rab geranylgeranyl transferase
    • Esposito G, De Falco F, Tinto N, Testa F, Vitagliano L, Tandurella IC, et al. 2011. Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with Rab geranylgeranyl transferase. Hum Mutat 32(12):1460-1469.
    • (2011) Hum Mutat , vol.32 , Issue.12 , pp. 1460-1469
    • Esposito, G.1    De Falco, F.2    Tinto, N.3    Testa, F.4    Vitagliano, L.5    Tandurella, I.C.6
  • 13
    • 0028343181 scopus 로고
    • The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase
    • Fujimura K, Tanaka K, Nakano A, Toh-e A. 1994. The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase. J Biol Chem 269:9205-9212. (Pubitemid 24209246)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.12 , pp. 9205-9212
    • Fujimura, K.1    Tanaka, K.2    Nakano, A.3    Toh-E, A.4
  • 15
    • 62549132506 scopus 로고    scopus 로고
    • The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells
    • Gerber E, Hemmerlin A, Hartmann M, Heintz D, Hartmann MA, Mutterer J, et al. 2009. The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells. Plant Cell 21:285-300.
    • (2009) Plant Cell , vol.21 , pp. 285-300
    • Gerber, E.1    Hemmerlin, A.2    Hartmann, M.3    Heintz, D.4    Hartmann, M.A.5    Mutterer, J.6
  • 16
    • 51949096166 scopus 로고    scopus 로고
    • Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
    • Guo Z, Wu YW, Das D, Delon C, Cramer J, Yu S, et al. 2008. Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. EMBO J 27:2444-2456.
    • (2008) EMBO J , vol.27 , pp. 2444-2456
    • Guo, Z.1    Wu, Y.W.2    Das, D.3    Delon, C.4    Cramer, J.5    Yu, S.6
  • 17
    • 18044374653 scopus 로고    scopus 로고
    • A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily
    • DOI 10.1016/j.jmb.2005.02.002
    • Hala M, Elias M, Zarsky V. 2005. A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily. J Mol Biol 348:1299-1313. (Pubitemid 40602381)
    • (2005) Journal of Molecular Biology , vol.348 , Issue.5 , pp. 1299-1313
    • Hala, M.1    Elias, M.2    Zarsky, V.3
  • 18
    • 77952154910 scopus 로고    scopus 로고
    • Arabidopsis RAB geranylgeranyl transferase beta-subunit mutant is constitutively photomorphogenic, and has shoot growth and gravitropic defects
    • Hala M, Soukupova H, Synek L, Zarsky V. 2010. Arabidopsis RAB geranylgeranyl transferase beta-subunit mutant is constitutively photomorphogenic, and has shoot growth and gravitropic defects. Plant J 62:615-627.
    • (2010) Plant J , vol.62 , pp. 615-627
    • Hala, M.1    Soukupova, H.2    Synek, L.3    Zarsky, V.4
  • 19
    • 78751656754 scopus 로고    scopus 로고
    • Role of Rab GTPases in membrane traffic and cell physiology
    • Hutagalung AH, Novick PJ. 2011. Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 91:119-149.
    • (2011) Physiol Rev , vol.91 , pp. 119-149
    • Hutagalung, A.H.1    Novick, P.J.2
  • 20
    • 0031900935 scopus 로고    scopus 로고
    • A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene
    • Jacoby JJ, Nilius SM, Heinisch JJ. 1998. A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene. Mol Gen Genet 258:148-155.
    • (1998) Mol Gen Genet , vol.258 , pp. 148-155
    • Jacoby, J.J.1    Nilius, S.M.2    Heinisch, J.J.3
  • 21
    • 5444256434 scopus 로고    scopus 로고
    • A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size
    • DOI 10.1101/gad.1228804
    • Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M. 2004. A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev 18:2491-2505. (Pubitemid 39362892)
    • (2004) Genes and Development , vol.18 , Issue.20 , pp. 2491-2505
    • Jorgensen, P.1    Rupes, I.2    Sharom, J.R.3    Schneper, L.4    Broach, J.R.5    Tyers, M.6
  • 22
    • 29244438797 scopus 로고    scopus 로고
    • Spatial and temporal expression patterns of the choroideremia gene in the mouse retina
    • Keiser NW, Tang W, Wei Z, Bennett J. 2005. Spatial and temporal expression patterns of the choroideremia gene in the mouse retina. Mol Vis 11:1052-1060. (Pubitemid 41819457)
    • (2005) Molecular Vision , vol.11 , pp. 1052-1060
    • Keiser, N.W.1    Tang, W.2    Wei, Z.3    Bennett, J.4
  • 23
    • 0035692811 scopus 로고    scopus 로고
    • The leucine-rich repeat as a protein recognition motif
    • DOI 10.1016/S0959-440X(01)00266-4
    • Kobe B, Kajava AV. 2001. The leucine-rich repeat as a protein recognition motif. Curr Opin Struct Biol 11:725-732. (Pubitemid 34076634)
    • (2001) Current Opinion in Structural Biology , vol.11 , Issue.6 , pp. 725-732
    • Kobe, B.1    Kajava, A.V.2
  • 25
    • 81755189074 scopus 로고    scopus 로고
    • Regulation of b2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: Modulation of Rab geranylgeranylation by the receptor
    • Lachance V, Cartier A, Genier S, Munger S, Germain P, Labrecque P, et al. 2011. Regulation of b2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: Modulation of Rab geranylgeranylation by the receptor. J Biol Chem 286:40802-40813.
    • (2011) J Biol Chem , vol.286 , pp. 40802-40813
    • Lachance, V.1    Cartier, A.2    Genier, S.3    Munger, S.4    Germain, P.5    Labrecque, P.6
  • 27
    • 62549119989 scopus 로고    scopus 로고
    • Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling
    • Lempiainen H, Uotila A, Urban J, Dohnal I, Ammerer G, Loewith R, et al. 2009. Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling. Mol Cell 33:704-716.
    • (2009) Mol Cell , vol.33 , pp. 704-716
    • Lempiainen, H.1    Uotila, A.2    Urban, J.3    Dohnal, I.4    Ammerer, G.5    Loewith, R.6
  • 28
    • 33644748150 scopus 로고    scopus 로고
    • Thematic review series: Lipid posttranslational modifications; Geranylgeranylation of Rab GTPases
    • Leung KF, Baron R, Seabra MC. 2006. Thematic review series: Lipid posttranslational modifications; geranylgeranylation of Rab GTPases. J Lipid Res 47:467-475.
    • (2006) J Lipid Res , vol.47 , pp. 467-475
    • Leung, K.F.1    Baron, R.2    Seabra, M.C.3
  • 32
    • 84867926587 scopus 로고
    • Choroideremia
    • Pagon RA, Bird TD,Dolan CR, Stephens K, Adam MP, editors Seattle (WA); University of Washington. Seattle 1993-2003; [updated 3 June 2010]
    • MacDonald IM, Smaoui N, Seabra MC. Choroideremia. 1993. In: Pagon RA, Bird TD,Dolan CR, Stephens K, Adam MP, editors. GeneReviews-, Seattle (WA); University of Washington. Seattle: 1993-2003; [updated 3 June 2010].
    • (1993) GeneReviews
    • MacDonald, I.M.1    Smaoui, N.2    Seabra, M.C.3
  • 34
    • 0034954898 scopus 로고    scopus 로고
    • Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells
    • DOI 10.1002/yea.719
    • Miaczynska M, Wagner W, Bauer BE, Schweyen RJ, Ragnini A. 2001. Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells. Yeast 18:697-709. (Pubitemid 32590967)
    • (2001) Yeast , vol.18 , Issue.8 , pp. 697-709
    • Miaczynska, M.1    Wagner, W.2    Bauer, B.E.3    Schweyen, R.J.4    Ragnini, A.5
  • 35
    • 78751701335 scopus 로고    scopus 로고
    • Rab GTPases implicated in inherited and acquired disorders
    • Mitra S, Cheng KW, Mills GB. 2011. Rab GTPases implicated in inherited and acquired disorders. Semin Cell Dev Biol 22:57-68.
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 57-68
    • Mitra, S.1    Cheng, K.W.2    Mills, G.B.3
  • 36
    • 66849111207 scopus 로고    scopus 로고
    • Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia
    • Moosajee M, Tulloch M, Baron RA, Gregory-Evans CY, Pereira-Leal JB, Seabra MC. 2009. Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia. Invest Ophthalmol Vis Sci 50:3009-3016.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 3009-3016
    • Moosajee, M.1    Tulloch, M.2    Baron, R.A.3    Gregory-Evans, C.Y.4    Pereira-Leal, J.B.5    Seabra, M.C.6
  • 37
    • 0030467967 scopus 로고    scopus 로고
    • The C2 domain calcium-binding motif: Structural and functional diversity
    • Nalefski EA, Falke JJ. 1996. The C2 domain calcium-binding motif: Structural and functional diversity. Protein Sci 5:2375-2390. (Pubitemid 26424851)
    • (1996) Protein Science , vol.5 , Issue.12 , pp. 2375-2390
    • Nalefski, E.A.1    Falke, J.J.2
  • 38
    • 0023425412 scopus 로고
    • Characterization of new mutants in the early part of the yeast secretory pathway isolated by a (3H)mannose suicide selection
    • Newman AP, Ferro-Novick S. 1987. Characterization of new mutants in the early part of the yeast secretory pathway isolated by a (3H)mannose suicide selection. J Cell Biol 105:1587-1594.
    • (1987) J Cell Biol , vol.105 , pp. 1587-1594
    • Newman, A.P.1    Ferro-Novick, S.2
  • 39
    • 77953453947 scopus 로고    scopus 로고
    • Understanding and exploiting protein prenyltransferases
    • Nguyen UT, Goody RS, Alexandrov K. 2010. Understanding and exploiting protein prenyltransferases. ChemBioChem 11:1194-1201.
    • (2010) ChemBioChem , vol.11 , pp. 1194-1201
    • Nguyen, U.T.1    Goody, R.S.2    Alexandrov, K.3
  • 40
  • 41
    • 70350161810 scopus 로고    scopus 로고
    • Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function
    • Pandit S, Paul S, Zhang L, Chen M, Durbin N, Harrison SM, et al. 2009. Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function. Genetics 183:195-206.
    • (2009) Genetics , vol.183 , pp. 195-206
    • Pandit, S.1    Paul, S.2    Zhang, L.3    Chen, M.4    Durbin, N.5    Harrison, S.M.6
  • 43
    • 0028146472 scopus 로고
    • The yeast protein Mrs6p, a homologue of the rabGDI and human choroideraemia proteins, affects cytoplasmic and mitochondrial functions
    • Ragnini A, Teply R, Waldherr M, Voskova A, Schweyen RJ. 1994. The yeast protein Mrs6p, a homologue of the rabGDI and human choroideraemia proteins, affects cytoplasmic and mitochondrial functions. Curr Genet 26:308-314. (Pubitemid 24297655)
    • (1994) Current Genetics , vol.26 , Issue.4 , pp. 308-314
    • Ragnini, A.1    Teply, R.2    Waldherr, M.3    Voskova, A.4    Schweyen, R.J.5
  • 44
    • 2942575037 scopus 로고    scopus 로고
    • Structure of the Rab7:REP-1 complex: Insights into the mechanism of Rab prenylation and choroideremia disease
    • DOI 10.1016/j.cell.2004.05.017, PII S0092867404004970
    • Rak A, Pylypenko O, Niculae A, Pyatkov K, Goody RS, Alexandrov K. 2004. Structure of the Rab7:REP-1 complex: Insights into the mechanism of Rab prenylation and choroideremia disease. Cell 117:749-760. (Pubitemid 38748891)
    • (2004) Cell , vol.117 , Issue.6 , pp. 749-760
    • Rak, A.1    Pylypenko, O.2    Niculae, A.3    Pyatkov, K.4    Goody, R.S.5    Alexandrov, K.6
  • 45
    • 18744385493 scopus 로고    scopus 로고
    • Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase
    • Rak A, Reents R, Pylypenko O, Niculae A, Sidorovitch V, Thoma NH, et al. 2001. Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase. J Struct Biol 136:158-161.
    • (2001) J Struct Biol , vol.136 , pp. 158-161
    • Rak, A.1    Reents, R.2    Pylypenko, O.3    Niculae, A.4    Sidorovitch, V.5    Thoma, N.H.6
  • 46
    • 34848893349 scopus 로고    scopus 로고
    • Multiple domain insertions and losses in the evolution of the Rab prenylation complex
    • Rasteiro R, Pereira-Leal JB. 2007. Multiple domain insertions and losses in the evolution of the Rab prenylation complex. BMC Evol Biol 7:140.
    • (2007) BMC Evol Biol , vol.7 , pp. 140
    • Rasteiro, R.1    Pereira-Leal, J.B.2
  • 47
    • 0021212980 scopus 로고
    • Choroideremia: A clinical, electron microscopic, and biochemical report
    • Rodrigues MM, Ballintine EJ, Wiggert BN, Lee L, Fletcher RT, Chader GJ. 1984. Choroideremia: A clinical, electron microscopic, and biochemical report. Ophthalmology 91:873-883. (Pubitemid 14088150)
    • (1984) Ophthalmology , vol.91 , Issue.7 , pp. 873-883
    • Rodrigues, M.M.1    Ballintine, E.J.2    Wiggert, B.N.3
  • 48
    • 79958716455 scopus 로고    scopus 로고
    • Biochemical and molecular mechanisms of action of bisphosphonates
    • Rogers MJ, Crockett JC, Coxon FP, Monkkonen J. 2011. Biochemical and molecular mechanisms of action of bisphosphonates. Bone 49:34-41.
    • (2011) Bone , vol.49 , pp. 34-41
    • Rogers, M.J.1    Crockett, J.C.2    Coxon, F.P.3    Monkkonen, J.4
  • 50
    • 0028822704 scopus 로고
    • Deficient geranylgeranylation of Ram/Rab27 in choroideremia
    • Seabra MC, Ho YK, Anant JS. 1995. Deficient geranylgeranylation of Ram/Rab27 in choroideremia. J Biol Chem 270: 24420-24427.
    • (1995) J Biol Chem , vol.270 , pp. 24420-24427
    • Seabra, M.C.1    Ho, Y.K.2    Anant, J.S.3
  • 51
    • 0030158607 scopus 로고    scopus 로고
    • New insights into the pathogenesis of choroideremia: A tale of two REPs
    • Seabra MC. 1996. New insights into the pathogenesis of choroideremia: A tale of two REPs. Ophthalmic Genet 17:43-46.
    • (1996) Ophthalmic Genet , vol.17 , pp. 43-46
    • Seabra, M.C.1
  • 54
    • 0035980133 scopus 로고    scopus 로고
    • Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II
    • Si X, Zeng Q, Ng CH, Hong W, Pallen CJ. 2001. Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II. J Biol Chem 276:32875-32882.
    • (2001) J Biol Chem , vol.276 , pp. 32875-32882
    • Si, X.1    Zeng, Q.2    Ng, C.H.3    Hong, W.4    Pallen, C.J.5
  • 55
    • 69249240177 scopus 로고    scopus 로고
    • A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis
    • Singh J, Tyers M. 2009. A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis. Genes Dev 23:1944-1958.
    • (2009) Genes Dev , vol.23 , pp. 1944-1958
    • Singh, J.1    Tyers, M.2
  • 56
    • 51049097495 scopus 로고    scopus 로고
    • Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants
    • Skorupinska-Tudek K, Poznanski J, Wojcik J, Bienkowski T, Szostkiewicz I, Zelman-Femiak M, et al. 2008. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. J Biol Chem 283:21024-21035.
    • (2008) J Biol Chem , vol.283 , pp. 21024-21035
    • Skorupinska-Tudek, K.1    Poznanski, J.2    Wojcik, J.3    Bienkowski, T.4    Szostkiewicz, I.5    Zelman-Femiak, M.6
  • 58
    • 77954043461 scopus 로고    scopus 로고
    • Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients
    • Strunnikova NV, Barb J, Sergeev YV, Thiagarajasubramanian A, Silvin C, Munson PJ, et al. 2009. Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients. PLoS One 4:e8402.
    • (2009) PLoS One , vol.4
    • Strunnikova, N.V.1    Barb, J.2    Sergeev, Y.V.3    Thiagarajasubramanian, A.4    Silvin, C.5    Munson, P.J.6
  • 59
    • 54449097634 scopus 로고    scopus 로고
    • Caenorhabditis elegans Rab escort protein (REP-1) differently regulates each Rab protein function and localization in a tissue-dependent manner
    • Tanaka D, Kameyama K, Okamoto H, Doi M. 2008. Caenorhabditis elegans Rab escort protein (REP-1) differently regulates each Rab protein function and localization in a tissue-dependent manner. Genes Cells 13:1141-1157.
    • (2008) Genes Cells , vol.13 , pp. 1141-1157
    • Tanaka, D.1    Kameyama, K.2    Okamoto, H.3    Doi, M.4
  • 60
    • 79958830549 scopus 로고    scopus 로고
    • Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function
    • Taylor A, Mules EH, Seabra MC, Helfrich MH, Rogers MJ, Coxon FP. 2011. Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function. Small Gtpases 2:131-142.
    • (2011) Small Gtpases , vol.2 , pp. 131-142
    • Taylor, A.1    Mules, E.H.2    Seabra, M.C.3    Helfrich, M.H.4    Rogers, M.J.5    Coxon, F.P.6
  • 61
    • 0035965993 scopus 로고    scopus 로고
    • Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1
    • Thoma NH, Iakovenko A, Goody RS, Alexandrov K. 2001a. Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1. J Biol Chem 276:48637-48643.
    • (2001) J Biol Chem , vol.276 , pp. 48637-48643
    • Thoma, N.H.1    Iakovenko, A.2    Goody, R.S.3    Alexandrov, K.4
  • 62
    • 0035965992 scopus 로고    scopus 로고
    • Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate
    • Thoma NH, Niculae A, Goody RS, Alexandrov K. 2001b. Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate. J Biol Chem 276:48631-48636.
    • (2001) J Biol Chem , vol.276 , pp. 48631-48636
    • Thoma, N.H.1    Niculae, A.2    Goody, R.S.3    Alexandrov, K.4
  • 64
    • 84858686208 scopus 로고    scopus 로고
    • CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the RPE of choroideremia mice
    • TolmachovaT,TolmachovOE,Wavre-ShaptonST,Tracey-WhiteD, Futter CE, Seabra MC. 2012. CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the RPE of choroideremia mice. J GeneMed 14(3):158-68.
    • (2012) J GeneMed , vol.14 , Issue.3 , pp. 158-168
    • Tolmachova, T.1    Tolmachov, O.E.2    Wavre-Shapton, S.T.3    Tracey-White, D.4    Futter, C.E.5    Seabra, M.C.6
  • 66
    • 65549160015 scopus 로고    scopus 로고
    • Griscelli syndrome: A model system to study vesicular trafficking
    • van Gele M, Dynoodt P, Lambert J. 2009. Griscelli syndrome: A model system to study vesicular trafficking. Pigment Cell Melanoma Res 22:268-282.
    • (2009) Pigment Cell Melanoma Res , vol.22 , pp. 268-282
    • Van Gele, M.1    Dynoodt, P.2    Lambert, J.3
  • 67
    • 0042208446 scopus 로고    scopus 로고
    • Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing
    • Vincent K, Wang Q, Jay S, Hobbs K, Rymond BC. 2003. Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing. Genetics 164:895-907. (Pubitemid 36935668)
    • (2003) Genetics , vol.164 , Issue.3 , pp. 895-907
    • Vincent, K.1    Wang, Q.2    Jay, S.3    Hobbs, K.4    Rymond, B.C.5
  • 69
    • 0029839489 scopus 로고    scopus 로고
    • Yeast geranylgeranyltransferase type-II: Steady state kinetic studies of the recombinant enzyme
    • DOI 10.1021/bi960500y
    • Witter DJ, Poulter CD. 1996.Yeast geranylgeranyltransferase type-II: Steady state kinetic studies of the recombinant enzyme. Biochemistry 35:10454-10463. (Pubitemid 26277305)
    • (1996) Biochemistry , vol.35 , Issue.32 , pp. 10454-10463
    • Witter, D.J.1    Dale Poulter, C.2
  • 71
    • 67649690942 scopus 로고    scopus 로고
    • Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation
    • Wu YW, Goody RS, Abagyan R, Alexandrov K. 2009. Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation. J Biol Chem 284:13185-13192.
    • (2009) J Biol Chem , vol.284 , pp. 13185-13192
    • Wu, Y.W.1    Goody, R.S.2    Abagyan, R.3    Alexandrov, K.4
  • 72
    • 0034653838 scopus 로고    scopus 로고
    • Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution
    • DOI 10.1016/S0969-2126(00)00102-7
    • Zhang H, Seabra MC, Deisenhofer J. 2000. Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution. Struct Fold Des 8:241-251. (Pubitemid 30148691)
    • (2000) Structure , vol.8 , Issue.3 , pp. 241-251
    • Zhang, H.1    Seabra, M.C.2    Deisenhofer, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.