-
1
-
-
0034898458
-
Organization of the Rab-GDI/CHM superfamily: The functional basis for choroideremia disease
-
DOI 10.1034/j.1600-0854.2001.20803.x
-
Alory C, Balch WE. 2001. Organization of the Rab-GDI/CHM superfamily: The functional basis for choroideremia disease. Traffic 2:532-543. (Pubitemid 32725398)
-
(2001)
Traffic
, vol.2
, Issue.8
, pp. 532-543
-
-
Alory, C.1
Balch, W.E.2
-
2
-
-
0141521588
-
Molecular evolution of the Rab-escortprotein/guanine-nucleotide- dissociation-inhibitor superfamily
-
Alory C, Balch WE. 2003. Molecular evolution of the Rab-escortprotein/ guanine-nucleotide-dissociation-inhibitor superfamily. Mol Biol Cell 14:3857-3867.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 3857-3867
-
-
Alory, C.1
Balch, W.E.2
-
3
-
-
0029797447
-
Amino- and carboxy-terminal domains of the yeast rab escort protein are both required for binding of Ypt small G proteins
-
Bauer BE, Lorenzetti S, Miaczynska M, Bui DM, Schweyen RJ, Ragnini A. 1996. Amino-and carboxy-terminal domains of the yeast Rab escort protein are both required for binding of Ypt small G proteins. Mol Biol Cell 7:1521-1533. (Pubitemid 26339726)
-
(1996)
Molecular Biology of the Cell
, vol.7
, Issue.10
, pp. 1521-1533
-
-
Bauer, B.E.1
Lorenzetti, S.2
Miaczynska, M.3
Bui, D.M.4
Schweyen, R.J.5
Ragnini, A.6
-
4
-
-
17444403210
-
The C2 domain of PKCdelta is a phosphotyrosine binding domain
-
Benes CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP. 2005. The C2 domain of PKCdelta is a phosphotyrosine binding domain. Cell 121:271-280.
-
(2005)
Cell
, vol.121
, pp. 271-280
-
-
Benes, C.H.1
Wu, N.2
Elia, A.E.3
Dharia, T.4
Cantley, L.C.5
Soltoff, S.P.6
-
5
-
-
0034062298
-
Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance
-
DOI 10.1046/j.1365-2958.2000.01782.x
-
Bialek-Wyrzykowska U, Bauer BE, Wagner W, Kohlwein SD, Schweyen RJ, Ragnini A. 2000. Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance. Mol Microbiol 35:1295-1311. (Pubitemid 30175507)
-
(2000)
Molecular Microbiology
, vol.35
, Issue.6
, pp. 1295-1311
-
-
Bialek-Wyrzykowska, U.1
Bauer, B.E.2
Wagner, W.3
Kohlwein, S.D.4
Schweyen, R.J.5
Ragnini, A.6
-
6
-
-
0031753250
-
A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1
-
Chen EJ, Frand AR, Chitouras E, Kaiser CA. 1998. A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1. Mol Cell Biol 18:7139-7146. (Pubitemid 28533033)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.12
, pp. 7139-7146
-
-
Chen, E.J.1
Frand, A.R.2
Chitouras, E.3
Kaiser, C.A.4
-
7
-
-
62749117198
-
Emerging roles for Rab family GTPases in human cancer
-
Chia WJ, Tang BL. 2009. Emerging roles for Rab family GTPases in human cancer. Biochim Biophys Acta 1795:110-116.
-
(2009)
Biochim Biophys Acta
, vol.1795
, pp. 110-116
-
-
Chia, W.J.1
Tang, B.L.2
-
8
-
-
84867961522
-
Choroideremia: A review of general findings and pathogenesis
-
Oct 21 in press
-
Coussa RG, Traboulsi EI. 2011. Choroideremia: A review of general findings and pathogenesis. Ophthalmic Genet Oct 21; in press.
-
(2011)
Ophthalmic Genet
-
-
Coussa, R.G.1
Traboulsi, E.I.2
-
9
-
-
0028040141
-
REP-2, a Rab escort protein encoded by the choroideremia-like gene
-
Cremers FP, Armstrong SA, Seabra MC, Brown MS, Goldstein JL. 1994. REP-2, a Rab escort protein encoded by the choroideremialike gene. J Biol Chem 269:2111-2117. (Pubitemid 24035421)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.3
, pp. 2111-2117
-
-
Cremers, F.P.M.1
Armstrong, S.A.2
Seabra, M.C.3
Brown, M.S.4
Goldstein, J.L.5
-
10
-
-
12944252970
-
Rab geranylgeranyl transferase α mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis
-
DOI 10.1073/pnas.080517697
-
Detter JC, Zhang Q, Mules EH, Novak EK, Mishra VS, Li W, et al. 2000. Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis. Proc Natl Acad Sci USA 97:4144-4149. (Pubitemid 30226101)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.8
, pp. 4144-4149
-
-
Detter, J.C.1
Zhang, Q.2
Mules, E.H.3
Novak, E.K.4
Mishra, V.S.5
Li, W.6
McMurtrie, E.B.7
Tchernev, V.T.8
Wallace, M.R.9
Seabra, M.C.10
Swank, R.T.11
Kingsmore, S.F.12
-
11
-
-
0037188391
-
Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates
-
DOI 10.1021/bi016067w
-
Dursina B, Thoma NH, Sidorovitch V, Niculae A, Iakovenko A, Rak A, et al. 2002. Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates. Biochemistry 41:6805-6816. (Pubitemid 34547372)
-
(2002)
Biochemistry
, vol.41
, Issue.21
, pp. 6805-6816
-
-
Dursina, B.1
Thoma, N.H.2
Sidorovitch, V.3
Niculae, A.4
Iakovenko, A.5
Rak, A.6
Albert, S.7
Ceacareanu, A.-C.8
Kolling, R.9
Herrmann, C.10
Goody, R.S.11
Alexandrov, K.12
-
12
-
-
81255136935
-
Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with Rab geranylgeranyl transferase
-
Esposito G, De Falco F, Tinto N, Testa F, Vitagliano L, Tandurella IC, et al. 2011. Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with Rab geranylgeranyl transferase. Hum Mutat 32(12):1460-1469.
-
(2011)
Hum Mutat
, vol.32
, Issue.12
, pp. 1460-1469
-
-
Esposito, G.1
De Falco, F.2
Tinto, N.3
Testa, F.4
Vitagliano, L.5
Tandurella, I.C.6
-
13
-
-
0028343181
-
The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase
-
Fujimura K, Tanaka K, Nakano A, Toh-e A. 1994. The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase. J Biol Chem 269:9205-9212. (Pubitemid 24209246)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.12
, pp. 9205-9212
-
-
Fujimura, K.1
Tanaka, K.2
Nakano, A.3
Toh-E, A.4
-
14
-
-
45549095235
-
New type of mutations in three Spanish families with choroideremia
-
Garcia-Hoyos M, Lorda-Sanchez I, Gomez-Garre P, Villaverde C, Cantalapiedra D, Bustamante A, et al. 2008. New type of mutations in three Spanish families with choroideremia. Invest Ophthalmol Vis Sci 49:1315-1321.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 1315-1321
-
-
Garcia-Hoyos, M.1
Lorda-Sanchez, I.2
Gomez-Garre, P.3
Villaverde, C.4
Cantalapiedra, D.5
Bustamante, A.6
-
15
-
-
62549132506
-
The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells
-
Gerber E, Hemmerlin A, Hartmann M, Heintz D, Hartmann MA, Mutterer J, et al. 2009. The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells. Plant Cell 21:285-300.
-
(2009)
Plant Cell
, vol.21
, pp. 285-300
-
-
Gerber, E.1
Hemmerlin, A.2
Hartmann, M.3
Heintz, D.4
Hartmann, M.A.5
Mutterer, J.6
-
16
-
-
51949096166
-
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
-
Guo Z, Wu YW, Das D, Delon C, Cramer J, Yu S, et al. 2008. Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. EMBO J 27:2444-2456.
-
(2008)
EMBO J
, vol.27
, pp. 2444-2456
-
-
Guo, Z.1
Wu, Y.W.2
Das, D.3
Delon, C.4
Cramer, J.5
Yu, S.6
-
17
-
-
18044374653
-
A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily
-
DOI 10.1016/j.jmb.2005.02.002
-
Hala M, Elias M, Zarsky V. 2005. A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily. J Mol Biol 348:1299-1313. (Pubitemid 40602381)
-
(2005)
Journal of Molecular Biology
, vol.348
, Issue.5
, pp. 1299-1313
-
-
Hala, M.1
Elias, M.2
Zarsky, V.3
-
18
-
-
77952154910
-
Arabidopsis RAB geranylgeranyl transferase beta-subunit mutant is constitutively photomorphogenic, and has shoot growth and gravitropic defects
-
Hala M, Soukupova H, Synek L, Zarsky V. 2010. Arabidopsis RAB geranylgeranyl transferase beta-subunit mutant is constitutively photomorphogenic, and has shoot growth and gravitropic defects. Plant J 62:615-627.
-
(2010)
Plant J
, vol.62
, pp. 615-627
-
-
Hala, M.1
Soukupova, H.2
Synek, L.3
Zarsky, V.4
-
19
-
-
78751656754
-
Role of Rab GTPases in membrane traffic and cell physiology
-
Hutagalung AH, Novick PJ. 2011. Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 91:119-149.
-
(2011)
Physiol Rev
, vol.91
, pp. 119-149
-
-
Hutagalung, A.H.1
Novick, P.J.2
-
20
-
-
0031900935
-
A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene
-
Jacoby JJ, Nilius SM, Heinisch JJ. 1998. A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene. Mol Gen Genet 258:148-155.
-
(1998)
Mol Gen Genet
, vol.258
, pp. 148-155
-
-
Jacoby, J.J.1
Nilius, S.M.2
Heinisch, J.J.3
-
21
-
-
5444256434
-
A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size
-
DOI 10.1101/gad.1228804
-
Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M. 2004. A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev 18:2491-2505. (Pubitemid 39362892)
-
(2004)
Genes and Development
, vol.18
, Issue.20
, pp. 2491-2505
-
-
Jorgensen, P.1
Rupes, I.2
Sharom, J.R.3
Schneper, L.4
Broach, J.R.5
Tyers, M.6
-
22
-
-
29244438797
-
Spatial and temporal expression patterns of the choroideremia gene in the mouse retina
-
Keiser NW, Tang W, Wei Z, Bennett J. 2005. Spatial and temporal expression patterns of the choroideremia gene in the mouse retina. Mol Vis 11:1052-1060. (Pubitemid 41819457)
-
(2005)
Molecular Vision
, vol.11
, pp. 1052-1060
-
-
Keiser, N.W.1
Tang, W.2
Wei, Z.3
Bennett, J.4
-
23
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
DOI 10.1016/S0959-440X(01)00266-4
-
Kobe B, Kajava AV. 2001. The leucine-rich repeat as a protein recognition motif. Curr Opin Struct Biol 11:725-732. (Pubitemid 34076634)
-
(2001)
Current Opinion in Structural Biology
, vol.11
, Issue.6
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
25
-
-
81755189074
-
Regulation of b2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: Modulation of Rab geranylgeranylation by the receptor
-
Lachance V, Cartier A, Genier S, Munger S, Germain P, Labrecque P, et al. 2011. Regulation of b2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: Modulation of Rab geranylgeranylation by the receptor. J Biol Chem 286:40802-40813.
-
(2011)
J Biol Chem
, vol.286
, pp. 40802-40813
-
-
Lachance, V.1
Cartier, A.2
Genier, S.3
Munger, S.4
Germain, P.5
Labrecque, P.6
-
26
-
-
55549130445
-
Geranylgeranyl transferase type II inhibition prevents myeloma bone disease
-
Lawson M, Coulton L, Ebetino F, Vanderkerken K, Croucher P. 2008. Geranylgeranyl transferase type II inhibition prevents myeloma bone disease. Biochem Biophys Res Commun 377:453-457.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 453-457
-
-
Lawson, M.1
Coulton, L.2
Ebetino, F.3
Vanderkerken, K.4
Croucher, P.5
-
27
-
-
62549119989
-
Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling
-
Lempiainen H, Uotila A, Urban J, Dohnal I, Ammerer G, Loewith R, et al. 2009. Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling. Mol Cell 33:704-716.
-
(2009)
Mol Cell
, vol.33
, pp. 704-716
-
-
Lempiainen, H.1
Uotila, A.2
Urban, J.3
Dohnal, I.4
Ammerer, G.5
Loewith, R.6
-
28
-
-
33644748150
-
Thematic review series: Lipid posttranslational modifications; Geranylgeranylation of Rab GTPases
-
Leung KF, Baron R, Seabra MC. 2006. Thematic review series: Lipid posttranslational modifications; geranylgeranylation of Rab GTPases. J Lipid Res 47:467-475.
-
(2006)
J Lipid Res
, vol.47
, pp. 467-475
-
-
Leung, K.F.1
Baron, R.2
Seabra, M.C.3
-
29
-
-
0034352949
-
5′-UTR structural organization, transcript expression, and mutational analysis of the human rab geranylgeranyl transferase α-subunit (RABGGTA) gene
-
DOI 10.1006/mgme.2000.3091
-
Li W, Detter JC, Weiss HJ, Cramer EM, Zhang Q, Novak EK, et al. 2000. 5¢-UTR structural organization, transcript expression, and mutational analysis of the human Rab geranylgeranyl transferase alpha-subunit (RABGGTA) gene. Mol Genet Metab 71:599-608. (Pubitemid 32040986)
-
(2000)
Molecular Genetics and Metabolism
, vol.71
, Issue.4
, pp. 599-608
-
-
Li, W.1
Detter, J.C.2
Weiss, H.J.3
Cramer, E.M.4
Zhang, Q.5
Novak, E.K.6
Favier, R.7
Kingsmore, S.F.8
Swank, R.T.9
-
30
-
-
0034982881
-
Cell transplantation as a treatment for retinal disease
-
DOI 10.1016/S1350-9462(01)00003-9, PII S1350946201000039
-
Lund RD, Kwan AS, Keegan DJ, Sauvé Y, Coffey PJ, Lawrence JM. 2001. Cell transplantation as a treatment for retinal disease. Prog Retin Eye Res 20:415-449. (Pubitemid 32523894)
-
(2001)
Progress in Retinal and Eye Research
, vol.20
, Issue.4
, pp. 415-449
-
-
Lund, R.D.1
Kwan, A.S.L.2
Keegan, D.J.3
Sauve, Y.4
Coffey, P.J.5
Lawrence, J.M.6
-
31
-
-
3142718999
-
Choroideremia gene testing
-
DOI 10.1586/14737159.4.4.478
-
MacDonald IM, Sereda C, McTaggart K, Mah D. 2004. Choroideremia gene testing. Expert Rev Mol Diagn 4:478-484. (Pubitemid 38915274)
-
(2004)
Expert Review of Molecular Diagnostics
, vol.4
, Issue.4
, pp. 478-484
-
-
MacDonald, I.M.1
Sereda, C.2
McTaggart, K.3
Mah, D.4
-
32
-
-
84867926587
-
Choroideremia
-
Pagon RA, Bird TD,Dolan CR, Stephens K, Adam MP, editors Seattle (WA); University of Washington. Seattle 1993-2003; [updated 3 June 2010]
-
MacDonald IM, Smaoui N, Seabra MC. Choroideremia. 1993. In: Pagon RA, Bird TD,Dolan CR, Stephens K, Adam MP, editors. GeneReviews-, Seattle (WA); University of Washington. Seattle: 1993-2003; [updated 3 June 2010].
-
(1993)
GeneReviews
-
-
MacDonald, I.M.1
Smaoui, N.2
Seabra, M.C.3
-
33
-
-
0030836594
-
The yeast Rab escort protein binds intracellular membranes in vivo and in vitro
-
DOI 10.1074/jbc.272.27.16972
-
Miaczynska M, Lorenzetti S, Bialek U, Benito-Moreno RM, Schweyen RJ, Ragnini A. 1997. The yeast Rab escort protein binds intracellular membranes in vivo and in vitro. J Biol Chem 272:16972-16977. (Pubitemid 27289800)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.27
, pp. 16972-16977
-
-
Miaczynska, M.1
Lorenzetti, S.2
Bialek, U.3
Benito-Moreno, R.M.4
Schweyen, R.J.5
Ragnini, A.6
-
34
-
-
0034954898
-
Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells
-
DOI 10.1002/yea.719
-
Miaczynska M, Wagner W, Bauer BE, Schweyen RJ, Ragnini A. 2001. Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells. Yeast 18:697-709. (Pubitemid 32590967)
-
(2001)
Yeast
, vol.18
, Issue.8
, pp. 697-709
-
-
Miaczynska, M.1
Wagner, W.2
Bauer, B.E.3
Schweyen, R.J.4
Ragnini, A.5
-
35
-
-
78751701335
-
Rab GTPases implicated in inherited and acquired disorders
-
Mitra S, Cheng KW, Mills GB. 2011. Rab GTPases implicated in inherited and acquired disorders. Semin Cell Dev Biol 22:57-68.
-
(2011)
Semin Cell Dev Biol
, vol.22
, pp. 57-68
-
-
Mitra, S.1
Cheng, K.W.2
Mills, G.B.3
-
36
-
-
66849111207
-
Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia
-
Moosajee M, Tulloch M, Baron RA, Gregory-Evans CY, Pereira-Leal JB, Seabra MC. 2009. Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia. Invest Ophthalmol Vis Sci 50:3009-3016.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 3009-3016
-
-
Moosajee, M.1
Tulloch, M.2
Baron, R.A.3
Gregory-Evans, C.Y.4
Pereira-Leal, J.B.5
Seabra, M.C.6
-
37
-
-
0030467967
-
The C2 domain calcium-binding motif: Structural and functional diversity
-
Nalefski EA, Falke JJ. 1996. The C2 domain calcium-binding motif: Structural and functional diversity. Protein Sci 5:2375-2390. (Pubitemid 26424851)
-
(1996)
Protein Science
, vol.5
, Issue.12
, pp. 2375-2390
-
-
Nalefski, E.A.1
Falke, J.J.2
-
38
-
-
0023425412
-
Characterization of new mutants in the early part of the yeast secretory pathway isolated by a (3H)mannose suicide selection
-
Newman AP, Ferro-Novick S. 1987. Characterization of new mutants in the early part of the yeast secretory pathway isolated by a (3H)mannose suicide selection. J Cell Biol 105:1587-1594.
-
(1987)
J Cell Biol
, vol.105
, pp. 1587-1594
-
-
Newman, A.P.1
Ferro-Novick, S.2
-
39
-
-
77953453947
-
Understanding and exploiting protein prenyltransferases
-
Nguyen UT, Goody RS, Alexandrov K. 2010. Understanding and exploiting protein prenyltransferases. ChemBioChem 11:1194-1201.
-
(2010)
ChemBioChem
, vol.11
, pp. 1194-1201
-
-
Nguyen, U.T.1
Goody, R.S.2
Alexandrov, K.3
-
40
-
-
62649118282
-
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging
-
Nguyen UT, Guo Z, Delon C, Wu Y, Deraeve C, Fränzel B, et al. 2009. Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nat Chem Biol 5:227-235.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 227-235
-
-
Nguyen, U.T.1
Guo, Z.2
Delon, C.3
Wu, Y.4
Deraeve, C.5
Fränzel, B.6
-
41
-
-
70350161810
-
Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function
-
Pandit S, Paul S, Zhang L, Chen M, Durbin N, Harrison SM, et al. 2009. Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function. Genetics 183:195-206.
-
(2009)
Genetics
, vol.183
, pp. 195-206
-
-
Pandit, S.1
Paul, S.2
Zhang, L.3
Chen, M.4
Durbin, N.5
Harrison, S.M.6
-
42
-
-
0037291870
-
Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase
-
DOI 10.1016/S1097-2765(03)00044-3
-
Pylypenko O, Rak A, Reents R, Niculae A, Sidorovitch V, Cioaca MD, et al. 2003. Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Mol Cell 11:483-494. (Pubitemid 36293840)
-
(2003)
Molecular Cell
, vol.11
, Issue.2
, pp. 483-494
-
-
Pylypenko, O.1
Rak, A.2
Reents, R.3
Niculae, A.4
Sidorovitch, V.5
Cioaca, M.-D.6
Bessolitsyna, E.7
Thoma, N.H.8
Waldmann, H.9
Schlichting, I.10
Goody, R.S.11
Alexandrov, K.12
-
43
-
-
0028146472
-
The yeast protein Mrs6p, a homologue of the rabGDI and human choroideraemia proteins, affects cytoplasmic and mitochondrial functions
-
Ragnini A, Teply R, Waldherr M, Voskova A, Schweyen RJ. 1994. The yeast protein Mrs6p, a homologue of the rabGDI and human choroideraemia proteins, affects cytoplasmic and mitochondrial functions. Curr Genet 26:308-314. (Pubitemid 24297655)
-
(1994)
Current Genetics
, vol.26
, Issue.4
, pp. 308-314
-
-
Ragnini, A.1
Teply, R.2
Waldherr, M.3
Voskova, A.4
Schweyen, R.J.5
-
44
-
-
2942575037
-
Structure of the Rab7:REP-1 complex: Insights into the mechanism of Rab prenylation and choroideremia disease
-
DOI 10.1016/j.cell.2004.05.017, PII S0092867404004970
-
Rak A, Pylypenko O, Niculae A, Pyatkov K, Goody RS, Alexandrov K. 2004. Structure of the Rab7:REP-1 complex: Insights into the mechanism of Rab prenylation and choroideremia disease. Cell 117:749-760. (Pubitemid 38748891)
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 749-760
-
-
Rak, A.1
Pylypenko, O.2
Niculae, A.3
Pyatkov, K.4
Goody, R.S.5
Alexandrov, K.6
-
45
-
-
18744385493
-
Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase
-
Rak A, Reents R, Pylypenko O, Niculae A, Sidorovitch V, Thoma NH, et al. 2001. Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase. J Struct Biol 136:158-161.
-
(2001)
J Struct Biol
, vol.136
, pp. 158-161
-
-
Rak, A.1
Reents, R.2
Pylypenko, O.3
Niculae, A.4
Sidorovitch, V.5
Thoma, N.H.6
-
46
-
-
34848893349
-
Multiple domain insertions and losses in the evolution of the Rab prenylation complex
-
Rasteiro R, Pereira-Leal JB. 2007. Multiple domain insertions and losses in the evolution of the Rab prenylation complex. BMC Evol Biol 7:140.
-
(2007)
BMC Evol Biol
, vol.7
, pp. 140
-
-
Rasteiro, R.1
Pereira-Leal, J.B.2
-
47
-
-
0021212980
-
Choroideremia: A clinical, electron microscopic, and biochemical report
-
Rodrigues MM, Ballintine EJ, Wiggert BN, Lee L, Fletcher RT, Chader GJ. 1984. Choroideremia: A clinical, electron microscopic, and biochemical report. Ophthalmology 91:873-883. (Pubitemid 14088150)
-
(1984)
Ophthalmology
, vol.91
, Issue.7
, pp. 873-883
-
-
Rodrigues, M.M.1
Ballintine, E.J.2
Wiggert, B.N.3
-
48
-
-
79958716455
-
Biochemical and molecular mechanisms of action of bisphosphonates
-
Rogers MJ, Crockett JC, Coxon FP, Monkkonen J. 2011. Biochemical and molecular mechanisms of action of bisphosphonates. Bone 49:34-41.
-
(2011)
Bone
, vol.49
, pp. 34-41
-
-
Rogers, M.J.1
Crockett, J.C.2
Coxon, F.P.3
Monkkonen, J.4
-
50
-
-
0028822704
-
Deficient geranylgeranylation of Ram/Rab27 in choroideremia
-
Seabra MC, Ho YK, Anant JS. 1995. Deficient geranylgeranylation of Ram/Rab27 in choroideremia. J Biol Chem 270: 24420-24427.
-
(1995)
J Biol Chem
, vol.270
, pp. 24420-24427
-
-
Seabra, M.C.1
Ho, Y.K.2
Anant, J.S.3
-
51
-
-
0030158607
-
New insights into the pathogenesis of choroideremia: A tale of two REPs
-
Seabra MC. 1996. New insights into the pathogenesis of choroideremia: A tale of two REPs. Ophthalmic Genet 17:43-46.
-
(1996)
Ophthalmic Genet
, vol.17
, pp. 43-46
-
-
Seabra, M.C.1
-
52
-
-
67349162970
-
The functional effect of pathogenic mutations in Rab escort protein 1
-
Sergeev YV, Smaoui N, Sui R, Stiles D, Gordiyenko N, Strunnikova N, et al. 2009. The functional effect of pathogenic mutations in Rab escort protein 1. Mutat Res 665:44-50.
-
(2009)
Mutat Res
, vol.665
, pp. 44-50
-
-
Sergeev, Y.V.1
Smaoui, N.2
Sui, R.3
Stiles, D.4
Gordiyenko, N.5
Strunnikova, N.6
-
53
-
-
3042822368
-
Choroideremia gene product affects trophoblast development and vascularization in mouse extra-embryonic tissues
-
DOI 10.1016/j.ydbio.2004.04.016, PII S0012160604003069
-
Shi W, van den Hurk JA, Alamo-Bethencourt V, Mayer W, Winkens HJ, Ropers HH, et al. 2004. Choroideremia gene product affects trophoblast development and vascularization in mouse extra-embryonic tissues. Dev Biol 272:53-65. (Pubitemid 38887284)
-
(2004)
Developmental Biology
, vol.272
, Issue.1
, pp. 53-65
-
-
Shi, W.1
Van Den Hurk, J.A.2
Alamo-Bethencourt, V.3
Mayer, W.4
Winkens, H.J.5
Ropers, H.-H.6
Cremers, F.P.M.7
Fundele, R.8
-
54
-
-
0035980133
-
Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II
-
Si X, Zeng Q, Ng CH, Hong W, Pallen CJ. 2001. Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II. J Biol Chem 276:32875-32882.
-
(2001)
J Biol Chem
, vol.276
, pp. 32875-32882
-
-
Si, X.1
Zeng, Q.2
Ng, C.H.3
Hong, W.4
Pallen, C.J.5
-
55
-
-
69249240177
-
A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis
-
Singh J, Tyers M. 2009. A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis. Genes Dev 23:1944-1958.
-
(2009)
Genes Dev
, vol.23
, pp. 1944-1958
-
-
Singh, J.1
Tyers, M.2
-
56
-
-
51049097495
-
Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants
-
Skorupinska-Tudek K, Poznanski J, Wojcik J, Bienkowski T, Szostkiewicz I, Zelman-Femiak M, et al. 2008. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. J Biol Chem 283:21024-21035.
-
(2008)
J Biol Chem
, vol.283
, pp. 21024-21035
-
-
Skorupinska-Tudek, K.1
Poznanski, J.2
Wojcik, J.3
Bienkowski, T.4
Szostkiewicz, I.5
Zelman-Femiak, M.6
-
57
-
-
1442281398
-
Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells
-
DOI 10.1073/pnas.0308474100
-
Starr CJ, Kappler JA, Chan DK, Kollmar R, Hudspeth AJ. 2004. Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells. Proc Natl Acad Sci USA 101:2572-2577. (Pubitemid 38269352)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.8
, pp. 2572-2577
-
-
Starr, C.J.1
Kappler, J.A.2
Chan, D.K.3
Kollmar, R.4
Hudspeth, A.J.5
-
58
-
-
77954043461
-
Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients
-
Strunnikova NV, Barb J, Sergeev YV, Thiagarajasubramanian A, Silvin C, Munson PJ, et al. 2009. Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients. PLoS One 4:e8402.
-
(2009)
PLoS One
, vol.4
-
-
Strunnikova, N.V.1
Barb, J.2
Sergeev, Y.V.3
Thiagarajasubramanian, A.4
Silvin, C.5
Munson, P.J.6
-
59
-
-
54449097634
-
Caenorhabditis elegans Rab escort protein (REP-1) differently regulates each Rab protein function and localization in a tissue-dependent manner
-
Tanaka D, Kameyama K, Okamoto H, Doi M. 2008. Caenorhabditis elegans Rab escort protein (REP-1) differently regulates each Rab protein function and localization in a tissue-dependent manner. Genes Cells 13:1141-1157.
-
(2008)
Genes Cells
, vol.13
, pp. 1141-1157
-
-
Tanaka, D.1
Kameyama, K.2
Okamoto, H.3
Doi, M.4
-
60
-
-
79958830549
-
Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function
-
Taylor A, Mules EH, Seabra MC, Helfrich MH, Rogers MJ, Coxon FP. 2011. Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function. Small Gtpases 2:131-142.
-
(2011)
Small Gtpases
, vol.2
, pp. 131-142
-
-
Taylor, A.1
Mules, E.H.2
Seabra, M.C.3
Helfrich, M.H.4
Rogers, M.J.5
Coxon, F.P.6
-
61
-
-
0035965993
-
Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1
-
Thoma NH, Iakovenko A, Goody RS, Alexandrov K. 2001a. Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1. J Biol Chem 276:48637-48643.
-
(2001)
J Biol Chem
, vol.276
, pp. 48637-48643
-
-
Thoma, N.H.1
Iakovenko, A.2
Goody, R.S.3
Alexandrov, K.4
-
62
-
-
0035965992
-
Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate
-
Thoma NH, Niculae A, Goody RS, Alexandrov K. 2001b. Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate. J Biol Chem 276:48631-48636.
-
(2001)
J Biol Chem
, vol.276
, pp. 48631-48636
-
-
Thoma, N.H.1
Niculae, A.2
Goody, R.S.3
Alexandrov, K.4
-
63
-
-
32444439446
-
Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia
-
DOI 10.1172/JCI26617
-
Tolmachova T, Anders R, Abrink M, Bugeon L, Dallman MJ, Futter CE, et al. 2006. Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia. J Clin Invest 116:386-394. (Pubitemid 43228355)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.2
, pp. 386-394
-
-
Tolmachova, T.1
Anders, R.2
Abrink, M.3
Bugeon, L.4
Dallman, M.J.5
Futter, C.E.6
Ramalho, J.S.7
Tonagel, F.8
Tanimoto, N.9
Seeliger, M.W.10
Huxley, C.11
Seabra, M.C.12
-
64
-
-
84858686208
-
CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the RPE of choroideremia mice
-
TolmachovaT,TolmachovOE,Wavre-ShaptonST,Tracey-WhiteD, Futter CE, Seabra MC. 2012. CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the RPE of choroideremia mice. J GeneMed 14(3):158-68.
-
(2012)
J GeneMed
, vol.14
, Issue.3
, pp. 158-168
-
-
Tolmachova, T.1
Tolmachov, O.E.2
Wavre-Shapton, S.T.3
Tracey-White, D.4
Futter, C.E.5
Seabra, M.C.6
-
65
-
-
8244220326
-
Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline
-
DOI 10.1093/hmg/6.6.851
-
van den Hurk JA, Hendriks W, van de Pol DJ, Oerlemans F, Jaissle G, Rüther K, et al. 1997. Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline. Hum Mol Genet 6:851-858. (Pubitemid 27239068)
-
(1997)
Human Molecular Genetics
, vol.6
, Issue.6
, pp. 851-858
-
-
Van Den Hurk, J.A.1
Hendriks, W.2
Van De Pol, D.J.R.3
Oerlemans, F.4
Jaissle, G.5
Ruther, K.6
Kohler, K.7
Hartmann, J.8
Zrenner, E.9
Van Bokhoven, H.10
Wieringa, B.11
Ropers, H.-H.12
Cremers, F.P.M.13
-
66
-
-
65549160015
-
Griscelli syndrome: A model system to study vesicular trafficking
-
van Gele M, Dynoodt P, Lambert J. 2009. Griscelli syndrome: A model system to study vesicular trafficking. Pigment Cell Melanoma Res 22:268-282.
-
(2009)
Pigment Cell Melanoma Res
, vol.22
, pp. 268-282
-
-
Van Gele, M.1
Dynoodt, P.2
Lambert, J.3
-
67
-
-
0042208446
-
Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing
-
Vincent K, Wang Q, Jay S, Hobbs K, Rymond BC. 2003. Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing. Genetics 164:895-907. (Pubitemid 36935668)
-
(2003)
Genetics
, vol.164
, Issue.3
, pp. 895-907
-
-
Vincent, K.1
Wang, Q.2
Jay, S.3
Hobbs, K.4
Rymond, B.C.5
-
69
-
-
0029839489
-
Yeast geranylgeranyltransferase type-II: Steady state kinetic studies of the recombinant enzyme
-
DOI 10.1021/bi960500y
-
Witter DJ, Poulter CD. 1996.Yeast geranylgeranyltransferase type-II: Steady state kinetic studies of the recombinant enzyme. Biochemistry 35:10454-10463. (Pubitemid 26277305)
-
(1996)
Biochemistry
, vol.35
, Issue.32
, pp. 10454-10463
-
-
Witter, D.J.1
Dale Poulter, C.2
-
70
-
-
33847042214
-
Cloning and characterization of Rab Escort Protein (REP) from Arabidopsis thaliana
-
DOI 10.1016/j.cellbi.2006.04.011, PII S1065699506002484
-
Wojtas M, Swiezewski S, Sarnowski TJ, Plochocka D, Chelstowska A, Tolmachova T, et al. 2007. Cloning and characterization of Rab Escort Protein (REP) from Arabidopsis thaliana. Cell Biol Int 31:246-251. (Pubitemid 46275479)
-
(2007)
Cell Biology International
, vol.31
, Issue.3
, pp. 246-251
-
-
Wojtas, M.1
Swiezewski, S.2
Sarnowski, T.J.3
Plochocka, D.4
Chelstowska, A.5
Tolmachova, T.6
Swiezewska, E.7
-
71
-
-
67649690942
-
Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation
-
Wu YW, Goody RS, Abagyan R, Alexandrov K. 2009. Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation. J Biol Chem 284:13185-13192.
-
(2009)
J Biol Chem
, vol.284
, pp. 13185-13192
-
-
Wu, Y.W.1
Goody, R.S.2
Abagyan, R.3
Alexandrov, K.4
-
72
-
-
0034653838
-
Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution
-
DOI 10.1016/S0969-2126(00)00102-7
-
Zhang H, Seabra MC, Deisenhofer J. 2000. Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution. Struct Fold Des 8:241-251. (Pubitemid 30148691)
-
(2000)
Structure
, vol.8
, Issue.3
, pp. 241-251
-
-
Zhang, H.1
Seabra, M.C.2
Deisenhofer, J.3
|