Rab geranylgeranyl transferase α mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 8, 2000, Pages 4144-4149

  Detter, John C ^a   Zhang, Qing ^b   Mules, Emilie H ^c   Novak, Edward K ^b   Mishra, Vishnu S ^a   Li, Wei ^b   McMurtrie, Elzbieta B ^a   Tchernev, Velizar T ^a   Wallace, Margaret R ^a   Seabra, Miguel C ^c   Swank, Richard T ^b   Kingsmore, Stephen F ^a,d,e  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^d Molecular Staging Inc   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; COMPLEMENTARY DNA; GERANYLGERANYL TRANSFERASE; MESSENGER RNA; RAB PROTEIN; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLEEDING DISORDER; CHOROIDEREMIA; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; GENE MUTATION; HEMOSTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENYLATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS; THROMBOCYTOSIS;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BLOOD PLATELETS; CELL DIVISION; CHROMOSOMES, ARTIFICIAL, YEAST; GENOTYPE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PROTEIN ISOPRENYLATION; RAB GTP-BINDING PROTEINS;

ANIMALIA;

EID: 12944252970     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.080517697     Document Type: Article

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