Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function

Small GTPases

Volumn 2, Issue 3, 2011, Pages 131-142

  Taylor, Adam ^a   Mules, Emilie H ^b   Seabra, Miguel C ^b,c,d   Helfrich, Miep H ^a   Rogers, Michael J ^a   Coxon, Fraser P ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^d INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

Bone; Bone resorption; Gunmetal; Osteoclast; Prenylation; Rab; Small GTPase

Indexed keywords

RAB GERANYLGERANYL TRANSFERASE; RAB PROTEIN; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE CELL; BONE DEFECT; BONE MASS; CELL FUNCTION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVITY; FEMALE; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MELANOCYTE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOMETRY; OSTEOSCLEROSIS; PHENOTYPE; POLARIZATION; PROTEIN PRENYLATION; REGULATORY MECHANISM; THROMBOCYTE; TRANSCYTOSIS;

MUS;

EID: 79958830549     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.2.3.16488     Document Type: Article

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