Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation

EMBO Journal

Volumn 27, Issue 18, 2008, Pages 2444-2456

  Guo, Zhong ^a   Wu, Yao Wen ^a   Das, Debapratim ^a   Delon, Christine ^a   Cramer, Janinna ^a   Yu, Shen ^a   Thuns, Sandra ^a   Lupilova, Nataliya ^a   Waldmann, Herbert ^a   Brunsveld, Luc ^a   Goody, Roger S ^a   Alexandrov, Kirill ^a,b   Blankenfeldt, Wulf ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Protein prenylation; Rab escort protein; Rab geranylgeranyl transferase; RabGTPases

Indexed keywords

CYSTEINE; DIMETHYLALLYLTRANSFERASE; GUANOSINE TRIPHOSPHATASE; ISOPRENOID PHOSPHATE; RAB ESCORT PROTEIN; RAB GERANYLGERANYL TRANSFERASE; RAB PROTEIN; RAB7 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBUNIT; FEMALE; MOLECULAR EVOLUTION; MOLECULAR MIMICRY; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; CYSTEINE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PRENYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RATS; THERMODYNAMICS;

EID: 51949096166     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.164     Document Type: Article

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