-
1
-
-
36348932768
-
COX-2 inhibitors and cardiovascular risk
-
DOI 10.1097/FJC.0b013e318157f72d, PII 0000534420071100000002
-
Funk CD, FitzGerald GA (2007) COX-2 inhibitors and cardiovascular risk. J Cardiovasc Pharmacol 50:470-479. (Pubitemid 350146448)
-
(2007)
Journal of Cardiovascular Pharmacology
, vol.50
, Issue.5
, pp. 470-479
-
-
Funk, C.D.1
FitzGerald, G.A.2
-
2
-
-
31044441042
-
Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities
-
DOI 10.1172/JCI27291
-
Grosser T, Fries S, FitzGerald GA (2006) Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities. J Clin Invest 116:4-15. (Pubitemid 43121782)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 4-15
-
-
Grosser, T.1
Fries, S.2
FitzGerald, G.A.3
-
3
-
-
38149029249
-
COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-inflammatory drugs
-
Warner TD, Mitchell JA (2008) COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-inflammatory drugs. Lancet 371:270-273.
-
(2008)
Lancet
, vol.371
, pp. 270-273
-
-
Warner, T.D.1
Mitchell, J.A.2
-
4
-
-
0025871150
-
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
-
Kujubu DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR (1991) TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 266:12866-12872.
-
(1991)
J Biol Chem
, vol.266
, pp. 12866-12872
-
-
Kujubu, D.A.1
Fletcher, B.S.2
Varnum, B.C.3
Lim, R.W.4
Herschman, H.R.5
-
5
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
Xie WL, Chipman JG, Robertson DL, Erikson RL, Simmons DL (1991) Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88:2692-2696. (Pubitemid 21916484)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.7
, pp. 2692-2696
-
-
Xie, W.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.L.4
Simmons, D.L.5
-
7
-
-
0036230988
-
Pharmacology of cyclooxygenase-2 inhibition in the kidney
-
DOI 10.1046/j.1523-1755.2002.00263.x
-
Khan KN, Paulson SK, Verburg KM, Lefkowith JB, Maziasz TJ (2002) Pharmacology of cyclooxygenase-2 inhibition in the kidney. Kidney Int 61:1210-1219. (Pubitemid 34304481)
-
(2002)
Kidney International
, vol.61
, Issue.4
, pp. 1210-1219
-
-
Khan, K.N.M.1
Paulson, S.K.2
Verburg, K.M.3
Lefkowith, J.B.4
Maziasz, T.J.5
-
8
-
-
21244441174
-
Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense
-
DOI 10.1038/sj.bjp.0706201
-
Wallace JL, Devchand PR (2005) Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense. Br J Pharmacol 145:275-282. (Pubitemid 40896072)
-
(2005)
British Journal of Pharmacology
, vol.145
, Issue.3
, pp. 275-282
-
-
Wallace, J.L.1
Devchand, P.R.2
-
9
-
-
84860205401
-
Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice
-
Yu Z, et al. (2012) Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice. Proc Natl Acad Sci USA 109:6727-6732.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 6727-6732
-
-
Yu, Z.1
-
10
-
-
84860703445
-
Vascular COX-2 modulates blood pressure and thrombosis in mice
-
Yu Y, et al. (2012) Vascular COX-2 modulates blood pressure and thrombosis in mice. Sci Transl Med 4(132):132ra154.
-
(2012)
Sci Transl Med
, vol.4
, Issue.132
-
-
Yu, Y.1
-
11
-
-
80053307147
-
Cardiovascular risk with non-steroidal anti-inflammatory drugs: Systematic review of population-based controlled observational studies
-
McGettigan P, Henry D (2011) Cardiovascular risk with non-steroidal anti-inflammatory drugs: Systematic review of population-based controlled observational studies. PLoS Med 8:e1001098.
-
(2011)
PLoS Med
, vol.8
-
-
McGettigan, P.1
Henry, D.2
-
12
-
-
34247464709
-
Use of nonsteroidal antiinflammatory drugs: An update for clinicians: A scientific statement from the American Heart Association
-
DOI 10.1161/CIRCULATIONAHA.106.181424
-
Antman EM, et al.; American Heart Association (2007) Use of nonsteroidal antiinflammatory drugs: An update for clinicians: a scientific statement from the American Heart Association. Circulation 115:1634-1642. (Pubitemid 46648649)
-
(2007)
Circulation
, vol.115
, Issue.12
, pp. 1634-1642
-
-
Antman, E.M.1
Bennett, J.S.2
Daugherty, A.3
Furberg, C.4
Roberts, H.5
Taubert, K.A.6
-
13
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
-
McAdam BF, et al. (1999) Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci USA 96:272-277.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
-
14
-
-
0032948948
-
Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids
-
Catella-Lawson F, et al. (1999) Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. J Pharmacol Exp Ther 289:735-741. (Pubitemid 29191226)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.289
, Issue.2
, pp. 735-741
-
-
Catella-Lawson, F.1
Mcadam, B.2
Morrison, B.W.3
Kapoor, S.4
Kujubu, D.5
Antes, L.6
Lasseter, K.C.7
Quan, H.8
Gertz, B.J.9
Fitzgerald, G.A.10
-
15
-
-
33845631867
-
Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events
-
DOI 10.1096/fj.06-6615com
-
Mitchell JA, et al. (2006) Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events. FASEB J 20:2468-2475. (Pubitemid 44953819)
-
(2006)
FASEB Journal
, vol.20
, Issue.14
, pp. 2468-2475
-
-
Mitchell, J.A.1
Lucas, R.2
Vojnovic, I.3
Hasan, K.4
Pepper, J.R.5
Warner, T.D.6
-
16
-
-
71349088198
-
Cyclooxygenase in normal human tissues - Is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?
-
Zidar N, et al. (2009) Cyclooxygenase in normal human tissues - is COX-1 really a constitutive isoform, and COX-2 an inducible isoform? J Cell Mol Med 13(9B):3753-3763.
-
(2009)
J Cell Mol Med
, vol.13
, Issue.9 B
, pp. 3753-3763
-
-
Zidar, N.1
-
17
-
-
0034702914
-
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis
-
Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ (2000) Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation 102:840-845.
-
(2000)
Circulation
, vol.102
, pp. 840-845
-
-
Belton, O.1
Byrne, D.2
Kearney, D.3
Leahy, A.4
Fitzgerald, D.J.5
-
18
-
-
33846094465
-
Double-label expression studies of prostacyclin synthase, thromboxane synthase and COX isoforms in normal aortic endothelium
-
DOI 10.1016/j.bbalip.2006.09.015, PII S1388198106002988
-
Kawka DW, Ouellet M, Hétu PO, Singer II, Riendeau D (2007) Double-label expression studies of prostacyclin synthase, thromboxane synthase and COX isoforms in normal aortic endothelium. Biochim Biophys Acta 1771:45-54. (Pubitemid 46073877)
-
(2007)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1771
, Issue.1
, pp. 45-54
-
-
Kawka, D.W.1
Ouellet, M.2
Hetu, P.-O.3
Singer, I.I.4
Riendeau, D.5
-
19
-
-
58449086980
-
Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation
-
Foudi N, Louedec L, Cachina T, Brink C, Norel X (2009) Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. Cardiovasc Res 81:269-277.
-
(2009)
Cardiovasc Res
, vol.81
, pp. 269-277
-
-
Foudi, N.1
Louedec, L.2
Cachina, T.3
Brink, C.4
Norel, X.5
-
20
-
-
33644870565
-
COX isoforms in the cardiovascular system: Understanding the activities of non-steroidal anti-inflammatory drugs
-
Mitchell JA, Warner TD (2006) COX isoforms in the cardiovascular system: Understanding the activities of non-steroidal anti-inflammatory drugs. Nat Rev Drug Discov 5:75-86.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 75-86
-
-
Mitchell, J.A.1
Warner, T.D.2
-
21
-
-
0035836653
-
Biomechanical activation of vascular endothelium as a determinant of its functional phenotype
-
DOI 10.1073/pnas.071052598
-
Garcia-Cardeña G, Comander J, Anderson KR, Blackman BR, Gimbrone MA, Jr. (2001) Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci USA 98:4478-4485. (Pubitemid 32295002)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.8
, pp. 4478-4485
-
-
Garcia-Cardena, G.1
Comander, J.2
Anderson, K.R.3
Blackman, B.R.4
Gimbrone Jr., M.A.5
-
22
-
-
0034607125
-
Effects of shear stress on eicosanoid gene expression and metabolite production in vascular endothelium as studied in a novel biomechanical perfusion model
-
DOI 10.1006/bbrc.2000.2279
-
Doroudi R, Gan LM, Selin Sjögren L, Jern S (2000) Effects of shear stress on eicosanoid gene expression and metabolite production in vascular endothelium as studied in a novel biomechanical perfusion model. Biochem Biophys Res Commun 269:257-264. (Pubitemid 30440287)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.269
, Issue.1
, pp. 257-264
-
-
Doroudi, R.1
Gan, L.-M.2
Selin, S.L.3
Jern, S.4
-
23
-
-
0029790770
-
Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress
-
Topper JN, Cai J, Falb D, Gimbrone MA, Jr. (1996) Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 93:10417-10422.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10417-10422
-
-
Topper, J.N.1
Cai, J.2
Falb, D.3
Gimbrone Jr., M.A.4
-
24
-
-
61949241329
-
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells
-
Di Francesco L, et al. (2009) Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. Circ Res 104:506-513.
-
(2009)
Circ Res
, vol.104
, pp. 506-513
-
-
Di Francesco, L.1
-
25
-
-
79551504871
-
Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms
-
Potter CM, et al. (2011) Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms. Arterioscler Thromb Vasc Biol 31:384-391.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 384-391
-
-
Potter, C.M.1
-
26
-
-
0036738406
-
Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells
-
Inoue H, et al. (2002) Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol 22:1415-1420.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1415-1420
-
-
Inoue, H.1
-
27
-
-
17344367171
-
Upregulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells
-
Okahara K, Sun B, Kambayashi J (1998) Upregulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol 18:1922-1926. (Pubitemid 28565755)
-
(1998)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.18
, Issue.12
, pp. 1922-1926
-
-
Okahara, K.1
Bing, S.2
Kambayashi, J.-I.3
-
28
-
-
0033597952
-
Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation
-
Iiyama K, et al. (1999) Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ Res 85:199-207. (Pubitemid 29343319)
-
(1999)
Circulation Research
, vol.85
, Issue.2
, pp. 199-207
-
-
Iiyama, K.1
Hajra, L.2
Iiyama, M.3
Li, H.4
DiChiara, M.5
Medoff, B.D.6
Cybulsky, M.I.7
-
29
-
-
0034255365
-
The NF-kappaB signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation
-
DOI 10.1073/pnas.97.16.9052
-
Hajra L, et al. (2000) The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc Natl Acad Sci USA 97:9052-9057. (Pubitemid 30626672)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.16
, pp. 9052-9057
-
-
Hajra, L.1
Evans, A.I.2
Chen, M.3
Hyduk, S.J.4
Collins, T.5
Cybulsky, M.I.6
-
30
-
-
33846413954
-
Hemodynamic shear stresses in mouse aortas: Implications for atherogenesis
-
DOI 10.1161/01.ATV.0000253492.45717.46, PII 0004360520070200000015
-
Suo J, et al. (2007) Hemodynamic shear stresses in mouse aortas: Implications for atherogenesis. Arterioscler Thromb Vasc Biol 27:346-351. (Pubitemid 46143050)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.2
, pp. 346-351
-
-
Suo, J.1
Ferrara, D.E.2
Sorescu, D.3
Guldberg, R.E.4
Taylor, W.R.5
Giddens, D.P.6
-
31
-
-
84856423507
-
Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries
-
Liu B, et al. (2012) Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries. Exp Physiol 97:277-289.
-
(2012)
Exp Physiol
, vol.97
, pp. 277-289
-
-
Liu, B.1
-
32
-
-
0027942832
-
Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: Regulation by dexamethasone
-
Mitchell JA, et al. (1994) Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: Regulation by dexamethasone. Br J Pharmacol 113:1008-1014. (Pubitemid 24326847)
-
(1994)
British Journal of Pharmacology
, vol.113
, Issue.3
, pp. 1008-1014
-
-
Mitchell, J.A.1
Belvisi, M.G.2
Akarasereenont, P.3
Robbins, R.A.4
Kwon, O.-J.5
Croxtall, J.6
Barnes, P.J.7
Vane, J.R.8
-
33
-
-
33646415952
-
Cyclooxygenases, microsomal prostaglandin e synthase-1, and cardiovascular function
-
Cheng Y, et al. (2006) Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. J Clin Invest 116:1391-1399.
-
(2006)
J Clin Invest
, vol.116
, pp. 1391-1399
-
-
Cheng, Y.1
-
34
-
-
0028328581
-
Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F(1alpha) by gas chromatography-mass spectrometry
-
DOI 10.1016/0378-4347(93)E0432-P
-
Daniel VC, Minton TA, Brown NJ, Nadeau JH, Morrow JD (1994) Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry. J Chromatogr B Biomed Appl 653:117-122. (Pubitemid 24085049)
-
(1994)
Journal of Chromatography B: Biomedical Applications
, vol.653
, Issue.2
, pp. 117-122
-
-
Daniel, V.C.1
Minton, T.A.2
Brown, N.J.3
Nadeau, J.H.4
Morrow, J.D.5
-
35
-
-
84862777870
-
Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome
-
Smith JP, et al. (2012) Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. Hypertension 59:719-725.
-
(2012)
Hypertension
, vol.59
, pp. 719-725
-
-
Smith, J.P.1
-
36
-
-
36349011990
-
The inducible nitric-oxide synthase modulates endothelin-1-dependent release of prostacyclin and inhibition of platelet aggregation ex vivo in the mouse
-
DOI 10.1124/jpet.107.125690
-
Carrier E, Brochu I, de Brum-Fernandes AJ, D'Orléans-Juste P (2007) The inducible nitric-oxide synthase modulates endothelin-1-dependent release of prostacyclin and inhibition of platelet aggregation ex vivo in the mouse. J Pharmacol Exp Ther 323:972-978. (Pubitemid 350146055)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.323
, Issue.3
, pp. 972-978
-
-
Carrier, E.1
Brochu, I.2
De Brum-Fernandes, A.J.3
D'Orleans-Juste, P.4
-
37
-
-
0030692018
-
Cyclooxygenases and the central nervous system
-
DOI 10.1016/S0090-6980(97)00128-7, PII S0090698097001287
-
Kaufmann WE, Andreasson KI, Isakson PC, Worley PF (1997) Cyclooxygenases and the central nervous system. Prostaglandins 54:601-624. (Pubitemid 27495921)
-
(1997)
Prostaglandins
, vol.54
, Issue.3
, pp. 601-624
-
-
Kaufmann, W.E.1
Andreasson, K.I.2
Isakson, P.C.3
Worley, P.F.4
-
38
-
-
0028843881
-
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
-
Langenbach R, et al. (1995) Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 83:483-492.
-
(1995)
Cell
, vol.83
, pp. 483-492
-
-
Langenbach, R.1
-
39
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morham SG, et al. (1995) Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83:473-482.
-
(1995)
Cell
, vol.83
, pp. 473-482
-
-
Morham, S.G.1
-
40
-
-
0034730178
-
Nociception in cyclooxygenase isozyme-deficient mice
-
Ballou LR, Botting RM, Goorha S, Zhang J, Vane JR (2000) Nociception in cyclooxygenase isozyme-deficient mice. Proc Natl Acad Sci USA 97:10272-10276.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10272-10276
-
-
Ballou, L.R.1
Botting, R.M.2
Goorha, S.3
Zhang, J.4
Vane, J.R.5
-
41
-
-
79956359185
-
Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse
-
Armstrong PC, et al. (2011) Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse. PLoS ONE 6:e20062.
-
(2011)
PLoS ONE
, vol.6
-
-
Armstrong, P.C.1
|