Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 9, 2002, Pages 1415-1420

  Inoue, Hiroyasu ^a   Taba, Yoji ^b   Miwa, Yoshikazu ^a   Yokota, Chiaki ^a   Miyagi, Megumi ^b   Sasaguri, Toshiyuki ^b  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Cyclooxygenase 2; Posttranscriptional regulation; Shear stress; Vascular endothelial cells

Indexed keywords

CYCLIC AMP; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; LUCIFERASE; MESSENGER RNA;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; CATTLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME REGULATION; EVALUATION; EXPRESSION VECTOR; GENE EXPRESSION; GENE INDUCTION; GENE INSERTION; GENETIC STABILITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MOTIF; REGULATORY MECHANISM; SHEAR STRESS; TRANSCRIPTION REGULATION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

3' UNTRANSLATED REGIONS; CELLS, CULTURED; CYCLOOXYGENASE 2; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RHEOLOGY; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; STRESS, MECHANICAL; TRANSCRIPTION, GENETIC; UMBILICAL VEINS;

EID: 0036738406     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000028816.13582.13     Document Type: Article

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