Differential regulation of human T lymphoblast functions by IL-2 and IL-15

Cytokine

Volumn 9, Issue 7, 1997, Pages 507-513

  Bulfone Paus, Silvia ^a   Dürkop, Horst ^a   Paus, Ralf ^b   Krause, Hans ^a   Pohl, Thomas ^a   Adrian, Onu ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Human T lymphoblasts; IL 15; IL 2

Indexed keywords

CD27 ANTIGEN; CD30 ANTIGEN; CD40 ANTIGEN; CONCANAVALIN A; CYTOKINE; CYTOKINE RECEPTOR; FAS ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; T LYMPHOCYTE ANTIGEN; TUMOR NECROSIS FACTOR RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOBLAST;

EID: 0031194209     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1996.0194     Document Type: Article

References (27)

1. 1. Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, Beers C, Richardson J, Schoenborn MA, Ahdieh M, Johnson J, Alderson MR, Watson JD, Anderson DM, Giri J (1994) Cloning of a cell growth factor that interacts with the β chain of the interleukin-2 receptor. Science 264:965-968.
2. 2. Bamford RN, Grant AJ, Burton JD, Peters C, Kurys G, Goldman CK, Brennan J, Roessler E, Waldmann TA (1994) The interleukin (IL)2 receptor β chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 91:4940-4994.
3. 3. Burton JD, Bamford RN, Peters C, Grant PA, Kurys G, Goldman CK, Brennan J, Roessler E, Waldmann TA (1994) A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 91:4935-4939.
4. 4. Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert D, Jenkins NA, Valentine V, Shapiro DN, Morris SW, Park LS, Cosman D (1995) Functional characterization of the human interleukin-15 receptor α chain and close linkage of IL15RA and IL2RA genes. J Biol Chem 270:29862-29869.
5. 5. Giri JG, Anderson DM, Kumaki S, Park LS, Grabstein KH, Cosman D (1995) IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2. J Leukocyte Biol 57:763-766.
6. 6. Armitage RJ, Macduff BM, Eisenmann J, Paxton R, Grabstein KH (1995) IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 154:483-490.
7. 7. Nishimura H, Hiromatsu K, Kobayashi N, Grabstein KH, Paxton R, Sugamura K, Bluestone JA, Yoshikai Y (1996) IL-15 is a novel growth factor for murine gd T cells induced by Salmonella infection. J Immunol 156:663-669.
8. 8. Wilkinson PC, Foo YL (1995) Chemoattraction of human blood T lymphocytes by interleukin-15. J Exp Med 181:1255-1259.
9. 9. McInnes IB, Al-Mughales J, Field M, Leung BP, Huang F-P, Dixon R, Sturrock RD, Wilkinson PC, Liew FW (1996) The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. Nature Medicine 2:175-182.
10. 10. Carson WE, Giri JG, Lindemann MJ, Linett ML, Ahdieh M, Paxton R, Anderson D, Eisenmann J, Grabstein K, Caligiuri MA (1994) Interleukin (IL)15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med 180:1395-1403.
11. 11. Gamero AM, Ussery D, Reintgen DS, Puleo CA, Djeu JY (1995) Interleukin 15 induction of lymphokine-activated killer cell function against autologous tumor cells in melanoma patient lymphocytes by a CD18-dependent, perforin-related mechanism. Cancer Res 55:4988-4994.
12. 12. Giri JG, Ahdieh M, Eisenman J, Shanebeck K, Grabstein K, Kumaki S, Namen A, Park LS, Cosman D, Anderson D (1994) Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 13:2822-2830.
13. 13. Giri JG, Kumaki S, Ahdieh M, Friend DJ, Loomis A, Shanebeck K, DuBosse R, Cosman D, Park LS, Anderson DM (1995) Identification and cloning of α novel IL-15 binding protein that is structurally related to the α chain of the IL-2 receptor. EMBO J 14:3654-3663.
14. 14. Di Santo J, Kühn R, Müller W (1995) Common cytokine receptor γ chain (γc)-dependent cytokines: understanding in vivo functions by gene targeting. Immunol Rev 148:19-34.
15. 15. Mohamadzadeh M, Takashima A, Dougherty I, Knop J, Bergtresser PR, Cruz Jr, PD (1995) Ultraviolet B radiation up-regulates the expression of IL-15 in human skin. J Immunol 155:4492-4496.
16. 16. Quinn LS, Haugk KL, Grabstein KH (1995) Interleukin-15: a novel anabolic cytokine for skeletal muscle. Endocrinology 136:3669-3672.
17. 17. Osawa H, Diamantstein T (1984) A rat monoclonal antibody that binds specifically to mouse T lymphoblasts and inhibits IL-2 receptor functions: a putative anti IL-2 receptor antibody. J Immunol 132:2445-2450.
18. 18. Kunzendorf U, Pohl T, Bulfone-Paus S, Krause H, Notter M, Onu A, Walz G, Diamantstein T (1996) Suppression of cell-mediated and humoral immune responses by an interleukin-2-immunoglobulin fusion protein in mice. J Clin Invest 97: 1204-1210.
19. 19. Platzer C, Richter G, Überla K, Hock H, Diamantstein T, Blankenstein T (1992) Analysis of cytokine mRNA levels in interleukin-4-transgenic mice by quantitative polymerase chain reaction. Eur J Immunol 22:1729-1184.
20. 20. Smith CA, Farrah T, Goodwin RG (1994) The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76:959-962.
21. 21. Janeway CA, Travers P (1996) Immunobiology. Curr. Biol & Garland, London. New York.
22. 22. Jain J, Loh C, Rao A (1995) Transcriptional regulation of the IL-2 gene. Curr Opin Biol 7:333-342.
23. 23. Paul WE: Pleiotropy and redundancy (1989) T cell-derived lymphokines in the immune response. Cell 57:521-524.
24. 24. Gerez L, Arad G, Efrat S, Ketzinel M, Kaempfer R (1995) Post-transcriptional regulation of human interleukin-2 gene expression at processing of precursor transcripts. J Biol Chem 270:19569-19575.
25. 25. Baine Y, Stankunas BM, Miller P, Hobbs C, Tiberio L, Koch J, Yoon K, Sawutz D, Surowy C (1995) Functional characterization of novel IL-2 transcriptional inhibitors. J Immunol 154:3667-3667.
26. + T cells. J Immunol 154:9-16.
27. 27. Debets R, Savelkoul FJ (1994) Cytokine antagonists and their potential therapeutic use. Immunol Today 15:455-458.