Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds

Development (Cambridge)

Volumn 139, Issue 22, 2012, Pages 4250-4260

  Bénazet, Jean Denis ^a,c   Pignatti, Emanuele ^a   Nugent, Ashleigh ^a   Unal, Erkan ^a,b   Laurent, Frédéric ^a   Zeller, Rolf ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

BMP signaling; Limb bud; Mouse

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; COLLAGEN TYPE 2; SMAD4 PROTEIN; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MUTANT; CHONDROGENESIS; CONNECTIVE TISSUE; CONTROLLED STUDY; GENE DISRUPTION; GENE MUTATION; LIMB BUD; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROGENESIS; COLLAGEN TYPE II; CONNECTIVE TISSUE; EXTREMITIES; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIMB BUDS; MICE; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; SOX9 TRANSCRIPTION FACTOR; STEM CELLS;

EID: 84867856630     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.084822     Document Type: Article

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