SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling

Development

Volumn 138, Issue 10, 2011, Pages 1913-1923

  Probst, Simone ^a   Kraemer, Conradin ^b   Demougin, Philippe ^a   Sheth, Rushikesh ^a,e   Martin, Gail R ^c   Shiratori, Hidetaka ^d   Hamada, Hiroshi ^d   Iber, Dagmar ^b   Zeller, Rolf ^a   Zuniga, Aimée ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d OSAKA UNIVERSITY   (Japan)

^e CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Fibroblast growth factor; Mathematical modelling; Mouse limb development; Retinoic acid; Sonic hedgehog; Systems biology

Indexed keywords

CYTOCHROME B; CYTOCHROME P450 26B1; RETINOIC ACID; SONIC HEDGEHOG PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DEVELOPMENT; DOWN REGULATION; FEEDBACK SYSTEM; GENE EXPRESSION; GENE INTERACTION; GENE TARGETING; GENETIC ANALYSIS; LIMB BUD; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; ECTODERM; ENZYME ACTIVATION; FEEDBACK, PHYSIOLOGICAL; FEMALE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; LIMB BUDS; MESODERM; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; SIGNAL TRANSDUCTION; TRETINOIN;

ERINACEIDAE;

EID: 79955553860     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.063966     Document Type: Article

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