-
1
-
-
84859245835
-
A quantitative, high-throughput reverse genetic screen reveals novel connections between Pre-mRNA splicing and 5′ and 3′ end transcript determinants
-
L.O. Albulescu, N. Sabet, M. Gudipati, N. Stepankiw, Z.J. Bergman, and T.C. Huffaker A quantitative, high-throughput reverse genetic screen reveals novel connections between Pre-mRNA splicing and 5′ and 3′ end transcript determinants PLoS Genet 8 2012 e1002530
-
(2012)
PLoS Genet
, vol.8
, pp. 1002530
-
-
Albulescu, L.O.1
Sabet, N.2
Gudipati, M.3
Stepankiw, N.4
Bergman, Z.J.5
Huffaker, T.C.6
-
2
-
-
67650299463
-
Control of alternative splicing through siRNA-mediated transcriptional gene silencing
-
M. Allo, V. Buggiano, J.P. Fededa, E. Petrillo, I. Schor, and M. de la Mata Control of alternative splicing through siRNA-mediated transcriptional gene silencing Nat Struct Mol Biol 16 2009 717 724
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 717-724
-
-
Allo, M.1
Buggiano, V.2
Fededa, J.P.3
Petrillo, E.4
Schor, I.5
De La Mata, M.6
-
3
-
-
84863393843
-
The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation
-
O. Anczukow, A.Z. Rosenberg, M. Akerman, S. Das, L. Zhan, and R. Karni The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation Nat Struct Mol Biol 19 2012 220 228
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 220-228
-
-
Anczukow, O.1
Rosenberg, A.Z.2
Akerman, M.3
Das, S.4
Zhan, L.5
Karni, R.6
-
4
-
-
34447130998
-
Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter
-
D. Angeloni, A. Danilkovitch-Miagkova, T. Ivanova, E. Braga, E. Zabarovsky, and M.I. Lerman Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter Oncogene 26 2007 4499 4512
-
(2007)
Oncogene
, vol.26
, pp. 4499-4512
-
-
Angeloni, D.1
Danilkovitch-Miagkova, A.2
Ivanova, T.3
Braga, E.4
Zabarovsky, E.5
Lerman, M.I.6
-
5
-
-
3442901352
-
Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression
-
C. Bardella, B. Costa, P. Maggiora, S. Patane, M. Olivero, and G.N. Ranzani Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression Cancer Res 64 2004 5154 5161
-
(2004)
Cancer Res
, vol.64
, pp. 5154-5161
-
-
Bardella, C.1
Costa, B.2
Maggiora, P.3
Patane, S.4
Olivero, M.5
Ranzani, G.N.6
-
6
-
-
38049054726
-
Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs
-
L.O. Barrera, Z. Li, A.D. Smith, K.C. Arden, W.K. Cavenee, and M.Q. Zhang Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs Genome Res 18 2008 46 59
-
(2008)
Genome Res
, vol.18
, pp. 46-59
-
-
Barrera, L.O.1
Li, Z.2
Smith, A.D.3
Arden, K.C.4
Cavenee, W.K.5
Zhang, M.Q.6
-
7
-
-
0037098860
-
VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma
-
D.O. Bates, T.G. Cui, J.M. Doughty, M. Winkler, M. Sugiono, and J.D. Shields VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma Cancer Res 62 2002 4123 4131
-
(2002)
Cancer Res
, vol.62
, pp. 4123-4131
-
-
Bates, D.O.1
Cui, T.G.2
Doughty, J.M.3
Winkler, M.4
Sugiono, M.5
Shields, J.D.6
-
8
-
-
77957772409
-
Exon-level transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities
-
A. Bemmo, C. Dias, A.A. Rose, C. Russo, P. Siegel, and J. Majewski Exon-level transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities PLoS One 5 2010 e11981
-
(2010)
PLoS One
, vol.5
, pp. 11981
-
-
Bemmo, A.1
Dias, C.2
Rose, A.A.3
Russo, C.4
Siegel, P.5
Majewski, J.6
-
9
-
-
79952768708
-
Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1
-
J.N. Boeckel, V. Guarani, M. Koyanagi, T. Roexe, A. Lengeling, and R.T. Schermuly Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1 Proc Natl Acad Sci U S A 108 2011 3276 3281
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3276-3281
-
-
Boeckel, J.N.1
Guarani, V.2
Koyanagi, M.3
Roexe, T.4
Lengeling, A.5
Schermuly, R.T.6
-
10
-
-
64749105982
-
Predictive value of survivin alternative transcript expression in locally advanced breast cancer patients treated with neoadjuvant chemotherapy
-
R. Boidot, F. Vegran, and S. Lizard-Nacol Predictive value of survivin alternative transcript expression in locally advanced breast cancer patients treated with neoadjuvant chemotherapy Int J Mol Med 23 2009 285 291
-
(2009)
Int J Mol Med
, vol.23
, pp. 285-291
-
-
Boidot, R.1
Vegran, F.2
Lizard-Nacol, S.3
-
12
-
-
84859872672
-
Exon skipping mutations in neurofibromatosis
-
E. Buratti, and D. Baralle Exon skipping mutations in neurofibromatosis Methods Mol Biol 867 2012 65 76
-
(2012)
Methods Mol Biol
, vol.867
, pp. 65-76
-
-
Buratti, E.1
Baralle, D.2
-
13
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
N. Cancer Genome Atlas
-
N. Cancer Genome Atlas Comprehensive molecular characterization of human colon and rectal cancer Nature 487 2012 330 337
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
14
-
-
84855343985
-
Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells
-
X. Cao, J. Geradts, M.W. Dewhirst, and H.W. Lo Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells Oncogene 31 2012 104 115
-
(2012)
Oncogene
, vol.31
, pp. 104-115
-
-
Cao, X.1
Geradts, J.2
Dewhirst, M.W.3
Lo, H.W.4
-
15
-
-
33744805985
-
Genome-wide analysis of mammalian promoter architecture and evolution
-
P. Carninci, A. Sandelin, B. Lenhard, S. Katayama, K. Shimokawa, and J. Ponjavic Genome-wide analysis of mammalian promoter architecture and evolution Nat Genet 38 2006 626 635
-
(2006)
Nat Genet
, vol.38
, pp. 626-635
-
-
Carninci, P.1
Sandelin, A.2
Lenhard, B.3
Katayama, S.4
Shimokawa, K.5
Ponjavic, J.6
-
16
-
-
33750930082
-
Diverse DNA methylation statuses at alternative promoters of human genes in various tissues
-
J. Cheong, Y. Yamada, R. Yamashita, T. Irie, A. Kanai, and H. Wakaguri Diverse DNA methylation statuses at alternative promoters of human genes in various tissues DNA Res 13 2006 155 167
-
(2006)
DNA Res
, vol.13
, pp. 155-167
-
-
Cheong, J.1
Yamada, Y.2
Yamashita, R.3
Irie, T.4
Kanai, A.5
Wakaguri, H.6
-
17
-
-
78651314191
-
Identification of preferential target sites for human DNA methyltransferases
-
S.H. Choi, K. Heo, H.M. Byun, W. An, W. Lu, and A.S. Yang Identification of preferential target sites for human DNA methyltransferases Nucleic Acids Res 39 2011 104 118
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 104-118
-
-
Choi, S.H.1
Heo, K.2
Byun, H.M.3
An, W.4
Lu, W.5
Yang, A.S.6
-
19
-
-
0029837671
-
A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype
-
C. Collesi, M.M. Santoro, G. Gaudino, and P.M. Comoglio A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype Mol Cell Biol 16 1996 5518 5526
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5518-5526
-
-
Collesi, C.1
Santoro, M.M.2
Gaudino, G.3
Comoglio, P.M.4
-
20
-
-
0030761276
-
Functional association between promoter structure and transcript alternative splicing
-
P. Cramer, C.G. Pesce, F.E. Baralle, and A.R. Kornblihtt Functional association between promoter structure and transcript alternative splicing Proc Natl Acad Sci U S A 94 1997 11456 11460
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 11456-11460
-
-
Cramer, P.1
Pesce, C.G.2
Baralle, F.E.3
Kornblihtt, A.R.4
-
21
-
-
0035858992
-
The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas
-
R. Dammann, T. Takahashi, and G.P. Pfeifer The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas Oncogene 20 2001 3563 3567
-
(2001)
Oncogene
, vol.20
, pp. 3563-3567
-
-
Dammann, R.1
Takahashi, T.2
Pfeifer, G.P.3
-
22
-
-
84861131874
-
Oncogenic splicing factor Srsf1 is a critical transcriptional target of Myc
-
S. Das, O. Anczukow, M. Akerman, and A.R. Krainer Oncogenic splicing factor Srsf1 is a critical transcriptional target of Myc Cell Rep 1 2012 110 117
-
(2012)
Cell Rep
, vol.1
, pp. 110-117
-
-
Das, S.1
Anczukow, O.2
Akerman, M.3
Krainer, A.R.4
-
23
-
-
78049416081
-
Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
-
C.J. David, and J.L. Manley Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged Genes Dev 24 2010 2343 2364
-
(2010)
Genes Dev
, vol.24
, pp. 2343-2364
-
-
David, C.J.1
Manley, J.L.2
-
24
-
-
41149149041
-
The functional consequences of alternative promoter use in mammalian genomes
-
R.V. Davuluri, Y. Suzuki, S. Sugano, C. Plass, and T.H. Huang The functional consequences of alternative promoter use in mammalian genomes Trends Genet 24 2008 167 177
-
(2008)
Trends Genet
, vol.24
, pp. 167-177
-
-
Davuluri, R.V.1
Suzuki, Y.2
Sugano, S.3
Plass, C.4
Huang, T.H.5
-
25
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
S.M. Dehm, L.J. Schmidt, H.V. Heemers, R.L. Vessella, and D.J. Tindall Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance Cancer Res 68 2008 5469 5477
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
26
-
-
39449090999
-
A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response
-
A. DiFeo, L. Feld, E. Rodriguez, C. Wang, D.G. Beer, and J.A. Martignetti A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response Cancer Res 68 2008 965 970
-
(2008)
Cancer Res
, vol.68
, pp. 965-970
-
-
Difeo, A.1
Feld, L.2
Rodriguez, E.3
Wang, C.4
Beer, D.G.5
Martignetti, J.A.6
-
27
-
-
77951739131
-
Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer
-
M. Dutertre, L. Gratadou, E. Dardenne, S. Germann, S. Samaan, and R. Lidereau Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer Cancer Res 70 2010 3760 3770
-
(2010)
Cancer Res
, vol.70
, pp. 3760-3770
-
-
Dutertre, M.1
Gratadou, L.2
Dardenne, E.3
Germann, S.4
Samaan, S.5
Lidereau, R.6
-
28
-
-
60549104588
-
Splice-site pairing is an intrinsically high fidelity process
-
K.L. Fox-Walsh, and K.J. Hertel Splice-site pairing is an intrinsically high fidelity process Proc Natl Acad Sci U S A 106 2009 1766 1771
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1766-1771
-
-
Fox-Walsh, K.L.1
Hertel, K.J.2
-
29
-
-
0026050131
-
An alternative technique of local anesthesia for vitreoretinal surgery
-
M.A. Friedberg, F.A. Spellman, A.R. Pilkerton, L.E. Perraut Jr., and R.F. Stephens An alternative technique of local anesthesia for vitreoretinal surgery Arch Ophthalmol 109 1991 1615 1616
-
(1991)
Arch Ophthalmol
, vol.109
, pp. 1615-1616
-
-
Friedberg, M.A.1
Spellman, F.A.2
Pilkerton, A.R.3
Perraut Jr., L.E.4
Stephens, R.F.5
-
30
-
-
78649331805
-
TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors
-
M. Fujitani, G.I. Cancino, C.B. Dugani, I.C. Weaver, A. Gauthier-Fisher, and A. Paquin TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors Curr Biol 20 2010 2058 2065
-
(2010)
Curr Biol
, vol.20
, pp. 2058-2065
-
-
Fujitani, M.1
Cancino, G.I.2
Dugani, C.B.3
Weaver, I.C.4
Gauthier-Fisher, A.5
Paquin, A.6
-
31
-
-
29144447982
-
Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene
-
C. Ghigna, S. Giordano, H. Shen, F. Benvenuto, F. Castiglioni, and P.M. Comoglio Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene Mol Cell 20 2005 881 890
-
(2005)
Mol Cell
, vol.20
, pp. 881-890
-
-
Ghigna, C.1
Giordano, S.2
Shen, H.3
Benvenuto, F.4
Castiglioni, F.5
Comoglio, P.M.6
-
32
-
-
72449197125
-
A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding
-
S. Gopalakrishnan, B.O. Van Emburgh, J. Shan, Z. Su, C.R. Fields, and J. Vieweg A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding Mol Cancer Res 7 2009 1622 1634
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1622-1634
-
-
Gopalakrishnan, S.1
Van Emburgh, B.O.2
Shan, J.3
Su, Z.4
Fields, C.R.5
Vieweg, J.6
-
33
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Z. Guo, X. Yang, F. Sun, R. Jiang, D.E. Linn, and H. Chen A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth Cancer Res 69 2009 2305 2313
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
-
34
-
-
75149125730
-
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
-
R. Gupta, P. Wikramasinghe, A. Bhattacharyya, F.A. Perez, S. Pal, and R.V. Davuluri Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data BMC Bioinformatics 11 Suppl. 1 2010 S65
-
(2010)
BMC Bioinformatics
, vol.11
, Issue.SUPPL. 1
, pp. 65
-
-
Gupta, R.1
Wikramasinghe, P.2
Bhattacharyya, A.3
Perez, F.A.4
Pal, S.5
Davuluri, R.V.6
-
35
-
-
0029032861
-
Methionine deprivation regulates the translation of functionally-distinct c-Myc proteins
-
S.R. Hann Methionine deprivation regulates the translation of functionally-distinct c-Myc proteins Adv Exp Med Biol 375 1995 107 116
-
(1995)
Adv Exp Med Biol
, vol.375
, pp. 107-116
-
-
Hann, S.R.1
-
36
-
-
54549123309
-
VEGF-A splicing: The key to anti-angiogenic therapeutics?
-
S.J. Harper, and D.O. Bates VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer 8 2008 880 887
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 880-887
-
-
Harper, S.J.1
Bates, D.O.2
-
37
-
-
77950560127
-
Identification of an alternative CD20 transcript variant in B-cell malignancies coding for a novel protein associated to rituximab resistance
-
C. Henry, M. Deschamps, P.S. Rohrlich, J.R. Pallandre, J.P. Remy-Martin, and M. Callanan Identification of an alternative CD20 transcript variant in B-cell malignancies coding for a novel protein associated to rituximab resistance Blood 115 2010 2420 2429
-
(2010)
Blood
, vol.115
, pp. 2420-2429
-
-
Henry, C.1
Deschamps, M.2
Rohrlich, P.S.3
Pallandre, J.R.4
Remy-Martin, J.P.5
Callanan, M.6
-
38
-
-
78049419464
-
Orphan CpG islands identify numerous conserved promoters in the mammalian genome
-
R.S. Illingworth, U. Gruenewald-Schneider, S. Webb, A.R. Kerr, K.D. James, and D.J. Turner Orphan CpG islands identify numerous conserved promoters in the mammalian genome PLoS Genet 6 2010
-
(2010)
PLoS Genet
, vol.6
-
-
Illingworth, R.S.1
Gruenewald-Schneider, U.2
Webb, S.3
Kerr, A.R.4
James, K.D.5
Turner, D.J.6
-
39
-
-
0025912340
-
The human fibroblast growth factor receptor genes: A common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain
-
D.E. Johnson, J. Lu, H. Chen, S. Werner, and L.T. Williams The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain Mol Cell Biol 11 1991 4627 4634
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4627-4634
-
-
Johnson, D.E.1
Lu, J.2
Chen, H.3
Werner, S.4
Williams, L.T.5
-
40
-
-
80053027909
-
Functional consequences of developmentally regulated alternative splicing
-
A. Kalsotra, and T.A. Cooper Functional consequences of developmentally regulated alternative splicing Nat Rev Genet 12 2011 715 729
-
(2011)
Nat Rev Genet
, vol.12
, pp. 715-729
-
-
Kalsotra, A.1
Cooper, T.A.2
-
41
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
R. Karni, E. de Stanchina, S.W. Lowe, R. Sinha, D. Mu, and A.R. Krainer The gene encoding the splicing factor SF2/ASF is a proto-oncogene Nat Struct Mol Biol 14 2007 185 193
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
De Stanchina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
Krainer, A.R.6
-
42
-
-
84860367807
-
What is bad in cancer is good in the embryo: Importance of EMT in neural crest development
-
L. Kerosuo, and M. Bronner-Fraser What is bad in cancer is good in the embryo: importance of EMT in neural crest development Semin Cell Dev Biol 23 2012 320 332
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 320-332
-
-
Kerosuo, L.1
Bronner-Fraser, M.2
-
43
-
-
1842831283
-
Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers
-
A.T. Kho, Q. Zhao, Z. Cai, A.J. Butte, J.Y. Kim, and S.L. Pomeroy Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers Genes Dev 18 2004 629 640
-
(2004)
Genes Dev
, vol.18
, pp. 629-640
-
-
Kho, A.T.1
Zhao, Q.2
Cai, Z.3
Butte, A.J.4
Kim, J.Y.5
Pomeroy, S.L.6
-
44
-
-
30044442791
-
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
-
K. Kimura, A. Wakamatsu, Y. Suzuki, T. Ota, T. Nishikawa, and R. Yamashita Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes Genome Res 16 2006 55 65
-
(2006)
Genome Res
, vol.16
, pp. 55-65
-
-
Kimura, K.1
Wakamatsu, A.2
Suzuki, Y.3
Ota, T.4
Nishikawa, T.5
Yamashita, R.6
-
45
-
-
61349098460
-
Differential chromatin marking of introns and expressed exons by H3K36me3
-
P. Kolasinska-Zwierz, T. Down, I. Latorre, T. Liu, X.S. Liu, and J. Ahringer Differential chromatin marking of introns and expressed exons by H3K36me3 Nat Genet 41 2009 376 381
-
(2009)
Nat Genet
, vol.41
, pp. 376-381
-
-
Kolasinska-Zwierz, P.1
Down, T.2
Latorre, I.3
Liu, T.4
Liu, X.S.5
Ahringer, J.6
-
46
-
-
19344363974
-
Promoter usage and alternative splicing
-
A.R. Kornblihtt Promoter usage and alternative splicing Curr Opin Cell Biol 17 2005 262 268
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 262-268
-
-
Kornblihtt, A.R.1
-
47
-
-
42449089029
-
Coupling transcription and alternative splicing
-
A.R. Kornblihtt Coupling transcription and alternative splicing Adv Exp Med Biol 623 2007 175 189
-
(2007)
Adv Exp Med Biol
, vol.623
, pp. 175-189
-
-
Kornblihtt, A.R.1
-
48
-
-
77955463831
-
Exon-level microarray analyses identify alternative splicing programs in breast cancer
-
A. Lapuk, H. Marr, L. Jakkula, H. Pedro, S. Bhattacharya, and E. Purdom Exon-level microarray analyses identify alternative splicing programs in breast cancer Mol Cancer Res 8 2010 961 974
-
(2010)
Mol Cancer Res
, vol.8
, pp. 961-974
-
-
Lapuk, A.1
Marr, H.2
Jakkula, L.3
Pedro, H.4
Bhattacharya, S.5
Purdom, E.6
-
49
-
-
41149136353
-
An intron-derived insertion/truncation mutation in the BCR-ABL kinase domain in chronic myeloid leukemia patients undergoing kinase inhibitor therapy
-
J. Laudadio, M.W. Deininger, M.J. Mauro, B.J. Druker, and R.D. Press An intron-derived insertion/truncation mutation in the BCR-ABL kinase domain in chronic myeloid leukemia patients undergoing kinase inhibitor therapy J Mol Diagn 10 2008 177 180
-
(2008)
J Mol Diagn
, vol.10
, pp. 177-180
-
-
Laudadio, J.1
Deininger, M.W.2
Mauro, M.J.3
Druker, B.J.4
Press, R.D.5
-
50
-
-
80053577349
-
Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas
-
C.V. Lefave, M. Squatrito, S. Vorlova, G.L. Rocco, C.W. Brennan, and E.C. Holland Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas EMBO J 30 2011 4084 4097
-
(2011)
EMBO J
, vol.30
, pp. 4084-4097
-
-
Lefave, C.V.1
Squatrito, M.2
Vorlova, S.3
Rocco, G.L.4
Brennan, C.W.5
Holland, E.C.6
-
51
-
-
84858440747
-
Metazoan promoters: Emerging characteristics and insights into transcriptional regulation
-
B. Lenhard, A. Sandelin, and P. Carninci Metazoan promoters: emerging characteristics and insights into transcriptional regulation Nat Rev Genet 13 2012 233 245
-
(2012)
Nat Rev Genet
, vol.13
, pp. 233-245
-
-
Lenhard, B.1
Sandelin, A.2
Carninci, P.3
-
52
-
-
48949092575
-
A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation
-
Z. Lian, A. Karpikov, J. Lian, M.C. Mahajan, S. Hartman, and M. Gerstein A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation Genome Res 18 2008 1224 1237
-
(2008)
Genome Res
, vol.18
, pp. 1224-1237
-
-
Lian, Z.1
Karpikov, A.2
Lian, J.3
Mahajan, M.C.4
Hartman, S.5
Gerstein, M.6
-
53
-
-
36849004469
-
Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing
-
H.G. Linhart, H. Lin, Y. Yamada, E. Moran, E.J. Steine, and S. Gokhale Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing Genes Dev 21 2007 3110 3122
-
(2007)
Genes Dev
, vol.21
, pp. 3110-3122
-
-
Linhart, H.G.1
Lin, H.2
Yamada, Y.3
Moran, E.4
Steine, E.J.5
Gokhale, S.6
-
54
-
-
33748351186
-
Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells
-
I. Listerman, A.K. Sapra, and K.M. Neugebauer Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells Nat Struct Mol Biol 13 2006 815 822
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 815-822
-
-
Listerman, I.1
Sapra, A.K.2
Neugebauer, K.M.3
-
55
-
-
70149107047
-
A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion
-
H.W. Lo, H. Zhu, X. Cao, A. Aldrich, and F. Ali-Osman A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion Cancer Res 69 2009 6790 6798
-
(2009)
Cancer Res
, vol.69
, pp. 6790-6798
-
-
Lo, H.W.1
Zhu, H.2
Cao, X.3
Aldrich, A.4
Ali-Osman, F.5
-
56
-
-
34548103765
-
The functional modulation of epigenetic regulators by alternative splicing
-
S. Lois, N. Blanco, M. Martinez-Balbas, and X. de la Cruz The functional modulation of epigenetic regulators by alternative splicing BMC Genomics 8 2007 252
-
(2007)
BMC Genomics
, vol.8
, pp. 252
-
-
Lois, S.1
Blanco, N.2
Martinez-Balbas, M.3
De La Cruz, X.4
-
57
-
-
35148819860
-
Multiple variants of the RON receptor tyrosine kinase: Biochemical properties, tumorigenic activities, and potential drug targets
-
Y. Lu, H.P. Yao, and M.H. Wang Multiple variants of the RON receptor tyrosine kinase: biochemical properties, tumorigenic activities, and potential drug targets Cancer Lett 257 2007 157 164
-
(2007)
Cancer Lett
, vol.257
, pp. 157-164
-
-
Lu, Y.1
Yao, H.P.2
Wang, M.H.3
-
58
-
-
2942738996
-
The Hedgehog response network: Sensors, switches, and routers
-
L. Lum, and P.A. Beachy The Hedgehog response network: sensors, switches, and routers Science 304 2004 1755 1759
-
(2004)
Science
, vol.304
, pp. 1755-1759
-
-
Lum, L.1
Beachy, P.A.2
-
59
-
-
79954769467
-
Three novel alternative splicing mutations in BCR-ABL1 detected in CML patients with resistance to kinase inhibitors
-
W. Ma, F. Giles, X. Zhang, X. Wang, Z. Zhang, and T.S. Lee Three novel alternative splicing mutations in BCR-ABL1 detected in CML patients with resistance to kinase inhibitors Int J Lab Hematol 33 2011 326 331
-
(2011)
Int J Lab Hematol
, vol.33
, pp. 326-331
-
-
Ma, W.1
Giles, F.2
Zhang, X.3
Wang, X.4
Zhang, Z.5
Lee, T.S.6
-
60
-
-
77957862641
-
JAK2 exon 14 deletion in patients with chronic myeloproliferative neoplasms
-
W. Ma, H. Kantarjian, X. Zhang, X. Wang, Z. Zhang, and C.H. Yeh JAK2 exon 14 deletion in patients with chronic myeloproliferative neoplasms PLoS One 5 2010 e12165
-
(2010)
PLoS One
, vol.5
, pp. 12165
-
-
Ma, W.1
Kantarjian, H.2
Zhang, X.3
Wang, X.4
Zhang, Z.5
Yeh, C.H.6
-
61
-
-
44949263899
-
Spectrum and characterisation of BRCA1 and BRCA2 deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer
-
E. Machackova, L. Foretova, M. Lukesova, P. Vasickova, M. Navratilova, and I. Coene Spectrum and characterisation of BRCA1 and BRCA2 deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer BMC Cancer 8 2008 140
-
(2008)
BMC Cancer
, vol.8
, pp. 140
-
-
MacHackova, E.1
Foretova, L.2
Lukesova, M.3
Vasickova, P.4
Navratilova, M.5
Coene, I.6
-
62
-
-
7344241591
-
Overexpression of the RON gene in human breast carcinoma
-
P. Maggiora, S. Marchio, M.C. Stella, M. Giai, A. Belfiore, and M. De Bortoli Overexpression of the RON gene in human breast carcinoma Oncogene 16 1998 2927 2933
-
(1998)
Oncogene
, vol.16
, pp. 2927-2933
-
-
Maggiora, P.1
Marchio, S.2
Stella, M.C.3
Giai, M.4
Belfiore, A.5
De Bortoli, M.6
-
64
-
-
80052960863
-
Next-generation transcriptome assembly
-
J.A. Martin, and Z. Wang Next-generation transcriptome assembly Nat Rev Genet 12 2011 671 682
-
(2011)
Nat Rev Genet
, vol.12
, pp. 671-682
-
-
Martin, J.A.1
Wang, Z.2
-
65
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
A.K. Maunakea, R.P. Nagarajan, M. Bilenky, T.J. Ballinger, C. D'Souza, and S.D. Fouse Conserved role of intragenic DNA methylation in regulating alternative promoters Nature 466 2010 253 257
-
(2010)
Nature
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
Nagarajan, R.P.2
Bilenky, M.3
Ballinger, T.J.4
D'Souza, C.5
Fouse, S.D.6
-
66
-
-
79952753928
-
Genome-wide analysis of alternative splicing in medulloblastoma identifies splicing patterns characteristic of normal cerebellar development
-
F. Menghi, T.S. Jacques, M. Barenco, E.C. Schwalbe, S.C. Clifford, and M. Hubank Genome-wide analysis of alternative splicing in medulloblastoma identifies splicing patterns characteristic of normal cerebellar development Cancer Res 71 2011 2045 2055
-
(2011)
Cancer Res
, vol.71
, pp. 2045-2055
-
-
Menghi, F.1
Jacques, T.S.2
Barenco, M.3
Schwalbe, E.C.4
Clifford, S.C.5
Hubank, M.6
-
67
-
-
0026570847
-
Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene
-
T. Miki, D.P. Bottaro, T.P. Fleming, C.L. Smith, W.H. Burgess, and A.M. Chan Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene Proc Natl Acad Sci U S A 89 1992 246 250
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 246-250
-
-
Miki, T.1
Bottaro, D.P.2
Fleming, T.P.3
Smith, C.L.4
Burgess, W.H.5
Chan, A.M.6
-
68
-
-
78751700506
-
Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer
-
C.M. Misquitta-Ali, E. Cheng, D. O'Hanlon, N. Liu, C.J. McGlade, and M.S. Tsao Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer Mol Cell Biol 31 2011 138 150
-
(2011)
Mol Cell Biol
, vol.31
, pp. 138-150
-
-
Misquitta-Ali, C.M.1
Cheng, E.2
O'Hanlon, D.3
Liu, N.4
McGlade, C.J.5
Tsao, M.S.6
-
69
-
-
73449118582
-
Exon array analysis of head and neck cancers identifies a hypoxia related splice variant of LAMA3 associated with a poor prognosis
-
C.S. Moller-Levet, G.N. Betts, A.L. Harris, J.J. Homer, C.M. West, and C.J. Miller Exon array analysis of head and neck cancers identifies a hypoxia related splice variant of LAMA3 associated with a poor prognosis PLoS Comput Biol 5 2009 e1000571
-
(2009)
PLoS Comput Biol
, vol.5
, pp. 1000571
-
-
Moller-Levet, C.S.1
Betts, G.N.2
Harris, A.L.3
Homer, J.J.4
West, C.M.5
Miller, C.J.6
-
70
-
-
70350524985
-
Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation
-
M.A. Morgan, E. Magnusdottir, T.C. Kuo, C. Tunyaplin, J. Harper, and S.J. Arnold Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation Mol Cell Biol 29 2009 5813 5827
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5813-5827
-
-
Morgan, M.A.1
Magnusdottir, E.2
Kuo, T.C.3
Tunyaplin, C.4
Harper, J.5
Arnold, S.J.6
-
71
-
-
0035863296
-
P53 induction prevents accumulation of aberrant transcripts in cancer cells
-
C. Moyret-Lalle, C. Duriez, J. Van Kerckhove, C. Gilbert, Q. Wang, and A. Puisieux p53 induction prevents accumulation of aberrant transcripts in cancer cells Cancer Res 61 2001 486 488
-
(2001)
Cancer Res
, vol.61
, pp. 486-488
-
-
Moyret-Lalle, C.1
Duriez, C.2
Van Kerckhove, J.3
Gilbert, C.4
Wang, Q.5
Puisieux, A.6
-
72
-
-
33744944548
-
Novel 5′ untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: Implications for drug resistance, tissue-specific expression, and alternative promoter usage
-
T. Nakanishi, K.J. Bailey-Dell, B.A. Hassel, K. Shiozawa, D.M. Sullivan, and J. Turner Novel 5′ untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific expression, and alternative promoter usage Cancer Res 66 2006 5007 5011
-
(2006)
Cancer Res
, vol.66
, pp. 5007-5011
-
-
Nakanishi, T.1
Bailey-Dell, K.J.2
Hassel, B.A.3
Shiozawa, K.4
Sullivan, D.M.5
Turner, J.6
-
73
-
-
48749088691
-
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis
-
G. Narla, A. DiFeo, Y. Fernandez, S. Dhanasekaran, F. Huang, and J. Sangodkar KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis J Clin Invest 118 2008 2711 2721
-
(2008)
J Clin Invest
, vol.118
, pp. 2711-2721
-
-
Narla, G.1
Difeo, A.2
Fernandez, Y.3
Dhanasekaran, S.4
Huang, F.5
Sangodkar, J.6
-
74
-
-
13944252065
-
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk
-
G. Narla, A. Difeo, H.L. Reeves, D.J. Schaid, J. Hirshfeld, and E. Hod A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk Cancer Res 65 2005 1213 1222
-
(2005)
Cancer Res
, vol.65
, pp. 1213-1222
-
-
Narla, G.1
Difeo, A.2
Reeves, H.L.3
Schaid, D.J.4
Hirshfeld, J.5
Hod, E.6
-
75
-
-
21344473196
-
Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread
-
G. Narla, A. DiFeo, S. Yao, A. Banno, E. Hod, and H.L. Reeves Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread Cancer Res 65 2005 5761 5768
-
(2005)
Cancer Res
, vol.65
, pp. 5761-5768
-
-
Narla, G.1
Difeo, A.2
Yao, S.3
Banno, A.4
Hod, E.5
Reeves, H.L.6
-
76
-
-
18244389734
-
KLF6, a candidate tumor suppressor gene mutated in prostate cancer
-
G. Narla, K.E. Heath, H.L. Reeves, D. Li, L.E. Giono, and A.C. Kimmelman KLF6, a candidate tumor suppressor gene mutated in prostate cancer Science 294 2001 2563 2566
-
(2001)
Science
, vol.294
, pp. 2563-2566
-
-
Narla, G.1
Heath, K.E.2
Reeves, H.L.3
Li, D.4
Giono, L.E.5
Kimmelman, A.C.6
-
77
-
-
84862777672
-
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
-
K.P. Ng, A.M. Hillmer, C.T. Chuah, W.C. Juan, T.K. Ko, and A.S. Teo A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer Nat Med 18 2012 521 528
-
(2012)
Nat Med
, vol.18
, pp. 521-528
-
-
Ng, K.P.1
Hillmer, A.M.2
Chuah, C.T.3
Juan, W.C.4
Ko, T.K.5
Teo, A.S.6
-
78
-
-
56349136033
-
Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors
-
D.G. Nowak, J. Woolard, E.M. Amin, O. Konopatskaya, M.A. Saleem, and A.J. Churchill Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors J Cell Sci 121 2008 3487 3495
-
(2008)
J Cell Sci
, vol.121
, pp. 3487-3495
-
-
Nowak, D.G.1
Woolard, J.2
Amin, E.M.3
Konopatskaya, O.4
Saleem, M.A.5
Churchill, A.J.6
-
79
-
-
34547935029
-
Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins
-
K.R. Ostler, E.M. Davis, S.L. Payne, B.B. Gosalia, J. Exposito-Cespedes, and M.M. Le Beau Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins Oncogene 26 2007 5553 5563
-
(2007)
Oncogene
, vol.26
, pp. 5553-5563
-
-
Ostler, K.R.1
Davis, E.M.2
Payne, S.L.3
Gosalia, B.B.4
Exposito-Cespedes, J.5
Le Beau, M.M.6
-
80
-
-
33644857367
-
The PowerAtlas: A power and sample size atlas for microarray experimental design and research
-
G.P. Page, J.W. Edwards, G.L. Gadbury, P. Yelisetti, J. Wang, and P. Trivedi The PowerAtlas: a power and sample size atlas for microarray experimental design and research BMC Bioinformatics 7 2006 84
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 84
-
-
Page, G.P.1
Edwards, J.W.2
Gadbury, G.L.3
Yelisetti, P.4
Wang, J.5
Trivedi, P.6
-
81
-
-
80051567157
-
Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development
-
S. Pal, R. Gupta, H. Kim, P. Wickramasinghe, V. Baubet, and L.C. Showe Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development Genome Res 21 2011 1260 1272
-
(2011)
Genome Res
, vol.21
, pp. 1260-1272
-
-
Pal, S.1
Gupta, R.2
Kim, H.3
Wickramasinghe, P.4
Baubet, V.5
Showe, L.C.6
-
82
-
-
56749098074
-
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
-
Q. Pan, O. Shai, L.J. Lee, B.J. Frey, and B.J. Blencowe Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing Nat Genet 40 2008 1413 1415
-
(2008)
Nat Genet
, vol.40
, pp. 1413-1415
-
-
Pan, Q.1
Shai, O.2
Lee, L.J.3
Frey, B.J.4
Blencowe, B.J.5
-
83
-
-
78149455880
-
Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors
-
A. Piekielko-Witkowska, H. Wiszomirska, A. Wojcicka, P. Poplawski, J. Boguslawska, and Z. Tanski Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors PLoS One 5 2010 e13690
-
(2010)
PLoS One
, vol.5
, pp. 13690
-
-
Piekielko-Witkowska, A.1
Wiszomirska, H.2
Wojcicka, A.3
Poplawski, P.4
Boguslawska, J.5
Tanski, Z.6
-
84
-
-
84861858441
-
MUTYH gene expression and alternative splicing in controls and polyposis patients
-
G. Plotz, M. Casper, J. Raedle, I. Hinrichsen, V. Heckel, and A. Brieger MUTYH gene expression and alternative splicing in controls and polyposis patients Hum Mutat 33 2012 1067 1074
-
(2012)
Hum Mutat
, vol.33
, pp. 1067-1074
-
-
Plotz, G.1
Casper, M.2
Raedle, J.3
Hinrichsen, I.4
Heckel, V.5
Brieger, A.6
-
85
-
-
62449179630
-
Conserved gene expression programs integrate mammalian prostate development and tumorigenesis
-
C. Pritchard, B. Mecham, R. Dumpit, I. Coleman, M. Bhattacharjee, and Q. Chen Conserved gene expression programs integrate mammalian prostate development and tumorigenesis Cancer Res 69 2009 1739 1747
-
(2009)
Cancer Res
, vol.69
, pp. 1739-1747
-
-
Pritchard, C.1
Mecham, B.2
Dumpit, R.3
Coleman, I.4
Bhattacharjee, M.5
Chen, Q.6
-
86
-
-
34447316207
-
Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma
-
R.O. Pritchard-Jones, D.B. Dunn, Y. Qiu, A.H. Varey, A. Orlando, and H. Rigby Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma Br J Cancer 97 2007 223 230
-
(2007)
Br J Cancer
, vol.97
, pp. 223-230
-
-
Pritchard-Jones, R.O.1
Dunn, D.B.2
Qiu, Y.3
Varey, A.H.4
Orlando, A.5
Rigby, H.6
-
87
-
-
34547499702
-
Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
-
P. Pruunsild, A. Kazantseva, T. Aid, K. Palm, and T. Timmusk Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters Genomics 90 2007 397 406
-
(2007)
Genomics
, vol.90
, pp. 397-406
-
-
Pruunsild, P.1
Kazantseva, A.2
Aid, T.3
Palm, K.4
Timmusk, T.5
-
88
-
-
76649088636
-
Alternative splicing and biological heterogeneity in prostate cancer
-
P. Rajan, D.J. Elliott, C.N. Robson, and H.Y. Leung Alternative splicing and biological heterogeneity in prostate cancer Nat Rev Urol 6 2009 454 460
-
(2009)
Nat Rev Urol
, vol.6
, pp. 454-460
-
-
Rajan, P.1
Elliott, D.J.2
Robson, C.N.3
Leung, H.Y.4
-
89
-
-
80051489977
-
AlleleSeq: Analysis of allele-specific expression and binding in a network framework
-
J. Rozowsky, A. Abyzov, J. Wang, P. Alves, D. Raha, and A. Harmanci AlleleSeq: analysis of allele-specific expression and binding in a network framework Mol Syst Biol 7 2011 522
-
(2011)
Mol Syst Biol
, vol.7
, pp. 522
-
-
Rozowsky, J.1
Abyzov, A.2
Wang, J.3
Alves, P.4
Raha, D.5
Harmanci, A.6
-
90
-
-
79952364016
-
Histone H3 lysine 9 trimethylation and HP1gamma favor inclusion of alternative exons
-
V. Saint-Andre, E. Batsche, C. Rachez, and C. Muchardt Histone H3 lysine 9 trimethylation and HP1gamma favor inclusion of alternative exons Nat Struct Mol Biol 18 2011 337 344
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 337-344
-
-
Saint-Andre, V.1
Batsche, E.2
Rachez, C.3
Muchardt, C.4
-
91
-
-
57349137675
-
Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
-
E.M. Schaeffer, L. Marchionni, Z. Huang, B. Simons, A. Blackman, and W. Yu Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer Oncogene 27 2008 7180 7191
-
(2008)
Oncogene
, vol.27
, pp. 7180-7191
-
-
Schaeffer, E.M.1
Marchionni, L.2
Huang, Z.3
Simons, B.4
Blackman, A.5
Yu, W.6
-
92
-
-
69949132191
-
Chromatin organization marks exon-intron structure
-
S. Schwartz, E. Meshorer, and G. Ast Chromatin organization marks exon-intron structure Nat Struct Mol Biol 16 2009 990 995
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 990-995
-
-
Schwartz, S.1
Meshorer, E.2
Ast, G.3
-
93
-
-
79961004638
-
The power of NGS technologies to delineate the genome organization in cancer: From mutations to structural variations and epigenetic alterations
-
M.R. Schweiger, M. Kerick, B. Timmermann, and M. Isau The power of NGS technologies to delineate the genome organization in cancer: from mutations to structural variations and epigenetic alterations Cancer Metastasis Rev 30 2011 199 210
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 199-210
-
-
Schweiger, M.R.1
Kerick, M.2
Timmermann, B.3
Isau, M.4
-
94
-
-
84856809261
-
A deacetylase-deficient SIRT1 variant opposes full-length SIRT1 in regulating tumor suppressor p53 and governs expression of cancer-related genes
-
Z.H. Shah, S.U. Ahmed, J.R. Ford, S.J. Allison, J.R. Knight, and J. Milner A deacetylase-deficient SIRT1 variant opposes full-length SIRT1 in regulating tumor suppressor p53 and governs expression of cancer-related genes Mol Cell Biol 32 2012 704 716
-
(2012)
Mol Cell Biol
, vol.32
, pp. 704-716
-
-
Shah, Z.H.1
Ahmed, S.U.2
Ford, J.R.3
Allison, S.J.4
Knight, J.R.5
Milner, J.6
-
95
-
-
47249159395
-
Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal
-
T. Shimokawa, U. Tostar, M. Lauth, R. Palaniswamy, M. Kasper, and R. Toftgard Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal J Biol Chem 283 2008 14345 14354
-
(2008)
J Biol Chem
, vol.283
, pp. 14345-14354
-
-
Shimokawa, T.1
Tostar, U.2
Lauth, M.3
Palaniswamy, R.4
Kasper, M.5
Toftgard, R.6
-
96
-
-
80455176999
-
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
-
S. Shukla, E. Kavak, M. Gregory, M. Imashimizu, B. Shutinoski, and M. Kashlev CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing Nature 479 2011 74 79
-
(2011)
Nature
, vol.479
, pp. 74-79
-
-
Shukla, S.1
Kavak, E.2
Gregory, M.3
Imashimizu, M.4
Shutinoski, B.5
Kashlev, M.6
-
97
-
-
33750696292
-
Expression of Aurora-B kinase and phosphorylated histone H3 in hepatocellular carcinoma
-
A. Sistayanarain, K. Tsuneyama, H. Zheng, H. Takahashi, K. Nomoto, and C. Cheng Expression of Aurora-B kinase and phosphorylated histone H3 in hepatocellular carcinoma Anticancer Res 26 2006 3585 3593
-
(2006)
Anticancer Res
, vol.26
, pp. 3585-3593
-
-
Sistayanarain, A.1
Tsuneyama, K.2
Zheng, H.3
Takahashi, H.4
Nomoto, K.5
Cheng, C.6
-
98
-
-
84860130221
-
Anti-VEGF/VEGFR therapy for cancer: Reassessing the target
-
B. Sitohy, J.A. Nagy, and H.F. Dvorak Anti-VEGF/VEGFR therapy for cancer: reassessing the target Cancer Res 72 2012 1909 1914
-
(2012)
Cancer Res
, vol.72
, pp. 1909-1914
-
-
Sitohy, B.1
Nagy, J.A.2
Dvorak, H.F.3
-
99
-
-
70350013550
-
Biased chromatin signatures around polyadenylation sites and exons
-
N. Spies, C.B. Nielsen, R.A. Padgett, and C.B. Burge Biased chromatin signatures around polyadenylation sites and exons Mol Cell 36 2009 245 254
-
(2009)
Mol Cell
, vol.36
, pp. 245-254
-
-
Spies, N.1
Nielsen, C.B.2
Padgett, R.A.3
Burge, C.B.4
-
100
-
-
47649124124
-
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome
-
M. Sultan, M.H. Schulz, H. Richard, A. Magen, A. Klingenhoff, and M. Scherf A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome Science 321 2008 956 960
-
(2008)
Science
, vol.321
, pp. 956-960
-
-
Sultan, M.1
Schulz, M.H.2
Richard, H.3
Magen, A.4
Klingenhoff, A.5
Scherf, M.6
-
101
-
-
78651308679
-
Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq
-
H. Sun, J. Wu, P. Wickramasinghe, S. Pal, R. Gupta, and A. Bhattacharyya Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq Nucleic Acids Res 39 2011 190 201
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 190-201
-
-
Sun, H.1
Wu, J.2
Wickramasinghe, P.3
Pal, S.4
Gupta, R.5
Bhattacharyya, A.6
-
102
-
-
0025358726
-
Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer
-
T. Takahashi, D. D'Amico, I. Chiba, D.L. Buchhagen, and J.D. Minna Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer J Clin Invest 86 1990 363 369
-
(1990)
J Clin Invest
, vol.86
, pp. 363-369
-
-
Takahashi, T.1
D'Amico, D.2
Chiba, I.3
Buchhagen, D.L.4
Minna, J.D.5
-
103
-
-
78349237716
-
P73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis
-
F. Talos, A. Abraham, A.V. Vaseva, L. Holembowski, S.E. Tsirka, and A. Scheel p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis Cell Death Differ 17 2011 1816 1829
-
(2011)
Cell Death Differ
, vol.17
, pp. 1816-1829
-
-
Talos, F.1
Abraham, A.2
Vaseva, A.V.3
Holembowski, L.4
Tsirka, S.E.5
Scheel, A.6
-
104
-
-
0037112372
-
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
-
C.G. Tepper, D.L. Boucher, P.E. Ryan, A.H. Ma, L. Xia, and L.F. Lee Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line Cancer Res 62 2002 6606 6614
-
(2002)
Cancer Res
, vol.62
, pp. 6606-6614
-
-
Tepper, C.G.1
Boucher, D.L.2
Ryan, P.E.3
Ma, A.H.4
Xia, L.5
Lee, L.F.6
-
105
-
-
13744254695
-
A large-scale analysis of mRNA polyadenylation of human and mouse genes
-
B. Tian, J. Hu, H. Zhang, and C.S. Lutz A large-scale analysis of mRNA polyadenylation of human and mouse genes Nucleic Acids Res 33 2005 201 212
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 201-212
-
-
Tian, B.1
Hu, J.2
Zhang, H.3
Lutz, C.S.4
-
106
-
-
33846870354
-
Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing
-
B. Tian, Z. Pan, and J.Y. Lee Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing Genome Res 17 2007 156 165
-
(2007)
Genome Res
, vol.17
, pp. 156-165
-
-
Tian, B.1
Pan, Z.2
Lee, J.Y.3
-
107
-
-
0027402152
-
Multiple promoters direct tissue-specific expression of the rat BDNF gene
-
T. Timmusk, K. Palm, M. Metsis, T. Reintam, V. Paalme, and M. Saarma Multiple promoters direct tissue-specific expression of the rat BDNF gene Neuron 10 1993 475 489
-
(1993)
Neuron
, vol.10
, pp. 475-489
-
-
Timmusk, T.1
Palm, K.2
Metsis, M.3
Reintam, T.4
Paalme, V.5
Saarma, M.6
-
108
-
-
53549134949
-
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
-
R. Tomasini, K. Tsuchihara, M. Wilhelm, M. Fujitani, A. Rufini, and C.C. Cheung TAp73 knockout shows genomic instability with infertility and tumor suppressor functions Genes Dev 22 2008 2677 2691
-
(2008)
Genes Dev
, vol.22
, pp. 2677-2691
-
-
Tomasini, R.1
Tsuchihara, K.2
Wilhelm, M.3
Fujitani, M.4
Rufini, A.5
Cheung, C.C.6
-
109
-
-
58749114575
-
Highly individual methylation patterns of alternative glucocorticoid receptor promoters suggest individualized epigenetic regulatory mechanisms
-
J.D. Turner, L.P. Pelascini, J.A. Macedo, and C.P. Muller Highly individual methylation patterns of alternative glucocorticoid receptor promoters suggest individualized epigenetic regulatory mechanisms Nucleic Acids Res 36 2008 7207 7218
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 7207-7218
-
-
Turner, J.D.1
Pelascini, L.P.2
MacEdo, J.A.3
Muller, C.P.4
-
110
-
-
0033576674
-
Stress-induced aberrant splicing of TSG101: Association to high tumor grade and p53 status in breast cancers
-
E. Turpin, B. Dalle, A. de Roquancourt, L.F. Plassa, M. Marty, and A. Janin Stress-induced aberrant splicing of TSG101: association to high tumor grade and p53 status in breast cancers Oncogene 18 1999 7834 7837
-
(1999)
Oncogene
, vol.18
, pp. 7834-7837
-
-
Turpin, E.1
Dalle, B.2
De Roquancourt, A.3
Plassa, L.F.4
Marty, M.5
Janin, A.6
-
111
-
-
79952446259
-
When one is better than two: RNA with dual functions
-
D. Ulveling, C. Francastel, and F. Hube When one is better than two: RNA with dual functions Biochimie 93 2011 633 644
-
(2011)
Biochimie
, vol.93
, pp. 633-644
-
-
Ulveling, D.1
Francastel, C.2
Hube, F.3
-
112
-
-
79958074728
-
Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
-
B.O. Van Emburgh, and K.D. Robertson Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants Nucleic Acids Res 39 2011 4984 5002
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 4984-5002
-
-
Van Emburgh, B.O.1
Robertson, K.D.2
-
113
-
-
42149152015
-
VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: Balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy
-
A.H. Varey, E.S. Rennel, Y. Qiu, H.S. Bevan, R.M. Perrin, and S. Raffy VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy Br J Cancer 98 2008 1366 1379
-
(2008)
Br J Cancer
, vol.98
, pp. 1366-1379
-
-
Varey, A.H.1
Rennel, E.S.2
Qiu, Y.3
Bevan, H.S.4
Perrin, R.M.5
Raffy, S.6
-
114
-
-
67349097457
-
Cancer-associated regulation of alternative splicing
-
J.P. Venables, R. Klinck, C. Koh, J. Gervais-Bird, A. Bramard, and L. Inkel Cancer-associated regulation of alternative splicing Nat Struct Mol Biol 16 2009 670 676
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 670-676
-
-
Venables, J.P.1
Klinck, R.2
Koh, C.3
Gervais-Bird, J.4
Bramard, A.5
Inkel, L.6
-
115
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
R.G. Verhaak, K.A. Hoadley, E. Purdom, V. Wang, Y. Qi, and M.D. Wilkerson Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 Cancer Cell 17 2010 98 110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
-
116
-
-
34548758543
-
Splicing in disease: Disruption of the splicing code and the decoding machinery
-
G.S. Wang, and T.A. Cooper Splicing in disease: disruption of the splicing code and the decoding machinery Nat Rev Genet 8 2007 749 761
-
(2007)
Nat Rev Genet
, vol.8
, pp. 749-761
-
-
Wang, G.S.1
Cooper, T.A.2
-
117
-
-
57749195712
-
RNA-Seq: A revolutionary tool for transcriptomics
-
Z. Wang, M. Gerstein, and M. Snyder RNA-Seq: a revolutionary tool for transcriptomics Nat Rev Genet 10 2009 57 63
-
(2009)
Nat Rev Genet
, vol.10
, pp. 57-63
-
-
Wang, Z.1
Gerstein, M.2
Snyder, M.3
-
118
-
-
35148842564
-
Blocking tumorigenic activities of colorectal cancer cells by a splicing RON receptor variant defective in the tyrosine kinase domain
-
M.H. Wang, W.F. Lao, D. Wang, Y.L. Luo, and H.P. Yao Blocking tumorigenic activities of colorectal cancer cells by a splicing RON receptor variant defective in the tyrosine kinase domain Cancer Biol Ther 6 2007 1121 1129
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1121-1129
-
-
Wang, M.H.1
Lao, W.F.2
Wang, D.3
Luo, Y.L.4
Yao, H.P.5
-
119
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
E.T. Wang, R. Sandberg, S. Luo, I. Khrebtukova, L. Zhang, and C. Mayr Alternative isoform regulation in human tissue transcriptomes Nature 456 2008 470 476
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
-
120
-
-
0042921152
-
Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase
-
M.H. Wang, D. Wang, and Y.Q. Chen Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase Carcinogenesis 24 2003 1291 1300
-
(2003)
Carcinogenesis
, vol.24
, pp. 1291-1300
-
-
Wang, M.H.1
Wang, D.2
Chen, Y.Q.3
-
121
-
-
33749020195
-
A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer
-
L. Wang, J. Wang, S. Sun, M. Rodriguez, P. Yue, and S.J. Jang A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer Int J Oncol 29 2006 201 207
-
(2006)
Int J Oncol
, vol.29
, pp. 201-207
-
-
Wang, L.1
Wang, J.2
Sun, S.3
Rodriguez, M.4
Yue, P.5
Jang, S.J.6
-
122
-
-
39749107403
-
Alternative polyadenylation signals and promoters act in concert to control tissue-specific expression of the Opitz syndrome gene MID1
-
J. Winter, M. Kunath, S. Roepcke, S. Krause, R. Schneider, and S. Schweiger Alternative polyadenylation signals and promoters act in concert to control tissue-specific expression of the Opitz syndrome gene MID1 BMC Mol Biol 8 2007 105
-
(2007)
BMC Mol Biol
, vol.8
, pp. 105
-
-
Winter, J.1
Kunath, M.2
Roepcke, S.3
Krause, S.4
Schneider, R.5
Schweiger, S.6
-
123
-
-
83755178897
-
Development of an effective therapy for chronic myelogenous leukemia
-
D.W. Woessner, C.S. Lim, and M.W. Deininger Development of an effective therapy for chronic myelogenous leukemia Cancer J 17 2011 477 486
-
(2011)
Cancer J
, vol.17
, pp. 477-486
-
-
Woessner, D.W.1
Lim, C.S.2
Deininger, M.W.3
-
124
-
-
17544363909
-
P73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
-
A. Yang, N. Walker, R. Bronson, M. Kaghad, M. Oosterwegel, and J. Bonnin p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours Nature 404 2000 99 103
-
(2000)
Nature
, vol.404
, pp. 99-103
-
-
Yang, A.1
Walker, N.2
Bronson, R.3
Kaghad, M.4
Oosterwegel, M.5
Bonnin, J.6
-
125
-
-
80053900941
-
Frequent pathway mutations of splicing machinery in myelodysplasia
-
K. Yoshida, M. Sanada, Y. Shiraishi, D. Nowak, Y. Nagata, and R. Yamamoto Frequent pathway mutations of splicing machinery in myelodysplasia Nature 478 2011 64 69
-
(2011)
Nature
, vol.478
, pp. 64-69
-
-
Yoshida, K.1
Sanada, M.2
Shiraishi, Y.3
Nowak, D.4
Nagata, Y.5
Yamamoto, R.6
-
126
-
-
63549091847
-
CDNA analysis demonstrates that the BRCA2 intronic variant IVS4-12del5 is a deleterious mutation
-
L. Zhang, R. Bacares, S. Boyar, C. Hudis, K. Nafa, and K. Offit cDNA analysis demonstrates that the BRCA2 intronic variant IVS4-12del5 is a deleterious mutation Mutat Res 663 2009 84 89
-
(2009)
Mutat Res
, vol.663
, pp. 84-89
-
-
Zhang, L.1
Bacares, R.2
Boyar, S.3
Hudis, C.4
Nafa, K.5
Offit, K.6
-
127
-
-
84860400560
-
BRCA1 R71K missense mutation contributes to cancer predisposition by increasing alternative transcript levels
-
L. Zhang, L. Chen, R. Bacares, J.M. Ruggeri, J. Somar, and Y. Kemel BRCA1 R71K missense mutation contributes to cancer predisposition by increasing alternative transcript levels Breast Cancer Res Treat 130 2011 1051 1056
-
(2011)
Breast Cancer Res Treat
, vol.130
, pp. 1051-1056
-
-
Zhang, L.1
Chen, L.2
Bacares, R.3
Ruggeri, J.M.4
Somar, J.5
Kemel, Y.6
-
128
-
-
0037448657
-
Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: Generation of different splicing RON variants and their oncogenic potential
-
Y.Q. Zhou, C. He, Y.Q. Chen, D. Wang, and M.H. Wang Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential Oncogene 22 2003 186 197
-
(2003)
Oncogene
, vol.22
, pp. 186-197
-
-
Zhou, Y.Q.1
He, C.2
Chen, Y.Q.3
Wang, D.4
Wang, M.H.5
-
129
-
-
80052594686
-
Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner
-
H.L. Zhou, M.N. Hinman, V.A. Barron, C. Geng, G. Zhou, and G. Luo Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner Proc Natl Acad Sci U S A 108 2011 E627 E635
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
-
-
Zhou, H.L.1
Hinman, M.N.2
Barron, V.A.3
Geng, C.4
Zhou, G.5
Luo, G.6
|