PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum

In Vitro Cellular and Developmental Biology - Animal

Volumn 36, Issue 5, 2000, Pages 309-319

  Le Poole, I Caroline ^d   Boissy, Raymond E ^e   Sarancarajan, Rangaprasad ^e   Chen, Jing ^a   Forristal, Judith J ^e   Sheth, Pranav ^e   Westerhof, Wiete ^b   Babcock, Geore ^c   Das, Pranab K ^e   Saelinger, Catharine B ^e  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b Dutch Institute for Pigmentary Disorders (SNIP)   (Netherlands)

^c SHRINERS HOSPITALS FOR CHILDREN   (United States)

^d LOYOLA UNIVERSITY HEALTH SYSTEM   (United States)

^e NONE

Author keywords

Dilated RER; HPV16; Immortalization; Melanocytes; Pigmentation; Telomerase; Vitiligo

Indexed keywords

TELOMERASE;

ARTICLE; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE EXPRESSION; HUMAN; HUMAN CELL; MELANOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN PIGMENTATION; VITILIGO;

ADULT; CELL LINE, TRANSFORMED; CLONE CELLS; ENDOPLASMIC RETICULUM, ROUGH; FEMALE; FLOW CYTOMETRY; HUMANS; MELANOCYTES; MICROSCOPY, ELECTRON; ONCOGENE PROTEINS, VIRAL; PIGMENTATION; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERASE; VITILIGO;

EID: 0033867342     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Boissy, R. E.; Liu, Y. Y.; Medrano, E. E.; Nordlund, J. J. Structural aberration of the rough endoplasmic retirulum and melanosome compartmentalization in long-term cultures from vitiligo patients. J. Investig. Dermatol. 97:395-404; 1991.
2. Boissy, R. E.; Zhao, Y.; Gahl, W. A. Altered protein localization in melanocytes from Hermansky-Pudlak syndrome: support for the role of the HPS gene product in intracellular trafficking. Lab. Invest. 78:1037-1048; 1998.
3. Galardi, E.; Mehrigan, A. H.; Hashimoto, K. Ultrastrucural study of vitiligo. Int. J. Dermatol. 32:269-271; 1993.
4. Halaban, R.; Alfano, F. D. Selective elimination of fibroblasts from cultures of normal human melanocytes. In Vitro 20:447-450; 1984.
5. Halbert, C. L.; Demers, G. W.; Galloway, D. A. The E7 gene of human papillomavirus type 16 is sufficient for immortalization of primary human epithelial cells. J. Virol. 65:473-178; 1991.
6. Hawley-Nelson, P.; Vousden, K. H.; Hubbert, N. L., et al. HPV16 E6 and E7 proteins cooperate to immortalize human foreski keratinocytes. EMBO J. 8:3905-3910: 1989.
7. Im, S.; Hann, S. K.; Kim, H. I., et al. Biologic characteristics of cultured human vitiligo melanocytes. Int. J. Dermatol. 33:556-562; 1994.
8. Jimbow, K.; Chen, H.; Park, J. Molecular mechanisms for TRP-1 involvement in vitiligo/leukoderma [abstract]. Pigment Cell Res. S5:234; 1996.
9. Jones, H. W. Record of the first physician to see Henrietta Lacks at the Johns Hopkins Hospital: history of the beginning of the HeLa cell line. Am. J. Obstet. Gynecol. 176:S227-S228; 1997.
10. Karnovsky, M. J. A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy [abstract]. J. Cell. Biol. 27:137: 1965.
11. Karnovsky, M. J. Use of ferrocyanide-reduced osmium tetroxide in electron microscopy [abstract]. J. Cell. Biol. 51:146; 1971.
12. Katano, M.; Saxton, R. E.; Cochran, A. J.; Irie, R. F. Establishment of an ascitic human melanoma cell line that metastasizes to lung and liver in nude mice. J. Cancer Res. Clin. Oncol. 108:197-203: 1984.
13. Kim, P. S.; Arvan, P. Endocrinopathies in the family of endoplasmic reticulum storage diseases: disorders of protein trafficking and the role of ER molecular chaperones. Endocr. Rev. 19:173-202; 1998.
14. Kiyono, T.; Foster, S. A.; Koop, J. I., et al. Both Rb/p16INK4A inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396:84-88; 1998.
15. Kovacs, S. O. Vitiligo, J. Am. Acad. Dermatol. 38:647-666: 1998.
16. Le Poole, I. C.; Boissy, R. E. Vitiligo. Semin. Cutan. Med. Surg. 16:3-14; 1997.
17. Le Poole, I. C.; van den Berg. F. M.; van den Wijngaard, R. M. J. G. J., et al. Generation of a human melanocyte cell line by introduction of HPV16 E6 and E7 genes. In Vitro 33:42-49: 1997.
18. Le Poole, I. C.; van den Wijngaard, R. M. J. G. J.; Westerhof, W., et al. Presence or absence of melanocytes from vitiligo lesions: an immunohistochemical investigation. J. Investig. Dermatol. 100:816-822: 1993.
19. Majumder, P.; Nordlund, J. J.; Nath, S. K. Pattern of familial aggregation of vitiligo. Arch. Dermatol. 129:994-998; 1993.
20. Marquardt, T.; Helenius, A. Misfolding and aggregation of newly synthesized proteins in the endoplasmic reticulum. 117:505-513; 1992.
21. McKeehan, W. L.; Barnes, D.; Reid, L., et al. Frontiers in mammalian cell culture. In Vitro Cell. Dev. Biol. 26:9-23; 1990.
22. Melbije, M.; Frisch, M. The role of pappilomaviruses in anogenital cancers. Semin. Cancer Biol. 8:307-313: 1998.
23. Moellmann, G.: Klein-Angerer, S.; Scollay, D. A., et al. Extracellular granular material and degeneration of keratinocytes in the normally pigmented epidermis of patients with vitiligo. J. Investig. Dermatol. 79:321-330; 1982.
24. Munger, K.; Scheffner, M.; Huibregtse, J. M.; Howley, P. M. Interactions of HPV16 E6 and E7 oncoproteins with tumour suppressor gene products. Cancer Surv. 12:197-217: 1992.
25. Nath, S. K.; Majumder, P. P.; Nordlund, J. J. Genetic epidemiology of vitiligo: multilocus recessivity cross-validated. Am. J. Hum. Genet. 55:981-990; 1994.
26. Niechitta, C. V.; Migliaccio, G.; Blobel, G. Biochemical assembly of the membrane components that mediate chain targeting and translocation. Cell 65:587-598; 1991.
27. Nordlund, J. J. The epidemiology and genetics of vitiligo. Clin. Dermatol. 15: 875-878: 1997.
28. Puri, N.; Mojamdar, M.; Ramaiah, A. In vitro growth characteristics of melanocytes obtained from adult normal and vitiligo subjects. J. Investig. Dermatol. 88:434-438: 1987.
29. Ramaiah, A.; Mojamdar, M.; Amarnath, V. M. Vitiligo in the SSK community of Bangalore. Indian J. Dermatol. Venereol. Leprol. 54:251-254: 1988.
30. Tomita, Y.; Yamamoto, H.; Sato, C., et al. Efficient culturing of human melanocytes from suction blisters. Tokohu J. Exp. Med. 147:219-320: 1985.
31. Xu, A.; Bellamy, A. R.; Taylor, J. A. BiP (GRP78) and endoplasmin (GRP94) are induced following rotavirus infection and bind transiently to an endoplasmic reticulum-localized virion compartment. J. Virol. 72: 9865-9872; 1998.
32. Zhang, J. X.; Braakman, I.; Matlack, K. E.; Helenius, A. Quality control in the secretory pathway: the role of calreticulin, calnexin and BiP in the retention of glycoproteins with C-terminal truncations. Mol. Biol. Cell 8:1943-1954; 1997.
33. Zhao, H.; Boissy, Y. L.; Abdel-Malek, Z.; King, R. A.; Nordlund, J. J.; Boissy, R. E. On the analysis of the pathophysiology of Chediak-Higashi syndrome. Defects expressed by cultured melanocytes. Lab. Invest. 71:25-34; 1994.