Phosphatidylinositol 3-kinase and Rab5 GTPase inversely regulate the Smad anchor for receptor activation (SARA) protein independently of transforming growth factor-β1

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 35815-35824

  Runyan, Constance E ^a   Liu, Zongyi ^a   Schnaper, H William ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CO-IMMUNOPRECIPITATIONS; DOWN-REGULATION; ENDOCYTIC VESICLES; ENDOSOMES; EPITHELIAL CELLS; LY294002; PHOSPHATIDYLINOSITOL 3-KINASE; PROMOTER LEVELS; PROTEIN EXPRESSIONS; SMAD ANCHOR FOR RECEPTOR ACTIVATIONS; SMOOTH MUSCLES; TRANSFORMING GROWTH FACTORS;

ENZYMES; MOLECULAR BIOLOGY;

PROTEINS;

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA SMOOTH MUSCLE ACTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85; PROTEIN P85ALPHA; RAB PROTEIN; SMAD ANCHOR FOR RECEPTOR ACTIVATION; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CELL ENLARGEMENT; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ACTINS; CELL LINE; CHROMONES; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; ENDOCYTOSIS; ENZYME INHIBITORS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MORPHOLINES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; RAB5 GTP-BINDING PROTEINS; SERINE ENDOPEPTIDASES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84867817888     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.380493     Document Type: Article

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