Mercuric compounds induce pancreatic islets dysfunction and apoptosis in vivo

International Journal of Molecular Sciences

Volumn 13, Issue 10, 2012, Pages 12349-12366

  Chen, Kuo Liang ^a   Liu, Shing Hwa ^b   Su, Chin Chuan ^c   Yen, Cheng Chieh ^d,e   Yang, Ching Yao ^f   Lee, Kuan I ^g   Tang, Feng Cheng ^c   Chen, Ya Wen ^h   Lu, Tien Hui ^h   Su, Yi Chang ⁱ   Huang, Chun Fa ⁱ  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^g BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^h CHINA MEDICAL UNIVERSITY   (Taiwan)

ⁱ CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Mercuric compounds; Oxidative stress; Pancreatic islets

Indexed keywords

CASPASE 3; CASPASE 7; GLUCOSE; GLUTATHIONE PEROXIDASE; INSULIN; MALONALDEHYDE; MESSENGER RNA; METHYLMERCURIC CHLORIDE; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN MDM2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; GLUCOSE BLOOD LEVEL; MERCURIC CHLORIDE; METHYLMERCURY DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BCL 2 GENE; CASPASE 3 GENE; CASPASE 7 GENE; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE LOCATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GPX GENE; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MCL 1 GENE; MDM 2 GENE; MOUSE; NFR2 GENE; NICK END LABELING; NONHUMAN; NOO1 GENE; OXIDATIVE STRESS; PANCREAS INJURY; PANCREAS ISLET DISEASE; TOXICITY TESTING; TUMOR SUPPRESSOR GENE; ANALYSIS; ANIMAL; BLOOD; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIPID PEROXIDATION; MALE; METABOLISM; PANCREAS ISLET;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CASPASE 3; CASPASE 7; GLUTATHIONE PEROXIDASE; INSULIN; ISLETS OF LANGERHANS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MERCURIC CHLORIDE; METHYLMERCURY COMPOUNDS; MICE; MICE, INBRED ICR; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84867801973     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131012349     Document Type: Article

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