-
1
-
-
2442563304
-
Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
-
Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 2004;126:1504-17.
-
(2004)
Gastroenterology
, vol.126
, pp. 1504-1517
-
-
Loftus Jr., E.V.1
-
3
-
-
34248136340
-
Inflammatory bowel disease: Clinical aspects and established and evolving therapies
-
Baumgart DC, Sandborn WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007;369:1641-57.
-
(2007)
Lancet
, vol.369
, pp. 1641-1657
-
-
Baumgart, D.C.1
Sandborn, W.J.2
-
4
-
-
0035080617
-
The risk of colorectal cancer in ulcerative colitis: A meta-analysis
-
Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001;48:526-35.
-
(2001)
Gut
, vol.48
, pp. 526-535
-
-
Eaden, J.A.1
Abrams, K.R.2
Mayberry, J.F.3
-
5
-
-
79953111192
-
Intestinal cancer risk in Crohn's disease: A metaanalysis
-
Laukoetter MG, Mennigen R, Hannig CM, Osada N, Rijcken E, Vowinkel T, et al. Intestinal cancer risk in Crohn's disease: a metaanalysis. J Gastrointest Surg 2011;15:576-83.
-
(2011)
J Gastrointest Surg
, vol.15
, pp. 576-583
-
-
Laukoetter, M.G.1
Mennigen, R.2
Hannig, C.M.3
Osada, N.4
Rijcken, E.5
Vowinkel, T.6
-
6
-
-
58149093077
-
Common NOD2 mutations are absent in patients with Crohn's disease in India
-
Pugazhendhi S, Amte A, Balamurugan R, Subramanian V, Ramakrishna BS. Common NOD2 mutations are absent in patients with Crohn's disease in India. Indian J Gastroenterol 2008;27:201-3.
-
(2008)
Indian J Gastroenterol
, vol.27
, pp. 201-203
-
-
Pugazhendhi, S.1
Amte, A.2
Balamurugan, R.3
Subramanian, V.4
Ramakrishna, B.S.5
-
7
-
-
33745473236
-
Family and twin studies in inflammatory bowel disease
-
Halme L, Paavola-Sakki P, Turunen U, Lappalainen M, Farkkila M, Kontula K. Family and twin studies in inflammatory bowel disease. World J Gastroenterol 2006;12:3668-72.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 3668-3672
-
-
Halme, L.1
Paavola-Sakki, P.2
Turunen, U.3
Lappalainen, M.4
Farkkila, M.5
Kontula, K.6
-
8
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
Zhernakova A, Van Diemen CC, Wijmenga C. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat Rev Genet 2009;10:43-55.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
Van Diemen, C.C.2
Wijmenga, C.3
-
10
-
-
55049111426
-
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 2008;40:1319-23.
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
Mayr, G.6
-
11
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
Franke A, Balschun T, Karlsen TH, Hedderich J, May S, Lu T, et al. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 2008;40:713-5.
-
(2008)
Nat Genet
, vol.40
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Hedderich, J.4
May, S.5
Lu, T.6
-
12
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007;39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
13
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007;39:830-2.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
-
14
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008;40:955-62.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
-
15
-
-
0035978533
-
A frameshift mutation in NOD2 asso ciated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, et al. A frameshift mutation in NOD2 asso ciated with susceptibility to Crohn's disease. Nature 2001;411:603-6.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
-
16
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxininduced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxininduced IL-1beta production. Nature 2008;456:264-8.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
-
17
-
-
74949138566
-
Studying inflammatory bowel disease in the global laboratory
-
Sachar DB. Studying inflammatory bowel disease in the global laboratory. J Gastrointestin Liver Dis 2009;18:407-9.
-
(2009)
J Gastrointestin Liver Dis
, vol.18
, pp. 407-409
-
-
Sachar, D.B.1
-
18
-
-
65949107547
-
Common genetic variation and human traits
-
Goldstein DB. Common genetic variation and human traits. N Engl J Med 2009;360:1696-8.
-
(2009)
N Engl J Med
, vol.360
, pp. 1696-1698
-
-
Goldstein, D.B.1
-
19
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald TT, Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005;307:1920-5.
-
(2005)
Science
, vol.307
, pp. 1920-1925
-
-
Macdonald, T.T.1
Monteleone, G.2
-
20
-
-
0035174046
-
Collaboration of epithelial cells with organized mucosal lymphoid tissues
-
Neutra MR, Mantis NJ, Kraehenbuhl JP. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat Immunol 2001;2:1004-9.
-
(2001)
Nat Immunol
, vol.2
, pp. 1004-1009
-
-
Neutra, M.R.1
Mantis, N.J.2
Kraehenbuhl, J.P.3
-
21
-
-
13744256812
-
Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity
-
Smythies LE, Sellers M, Clements RH, Mosteller-Barnum M, Meng G, Benjamin WH, et al. Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J Clin Invest 2005;115:66-75.
-
(2005)
J Clin Invest
, vol.115
, pp. 66-75
-
-
Smythies, L.E.1
Sellers, M.2
Clements, R.H.3
Mosteller-Barnum, M.4
Meng, G.5
Benjamin, W.H.6
-
22
-
-
0034040532
-
Chronic granulomatous disease. Report on a national registry of 368 patients
-
Winkelstein JA, Marino MC, Johnston RB Jr, Boyle J, Curnutte J, Gallin JI, et al. Chronic granulomatous disease. Report on a national registry of 368 patients. Medicine (Baltimore) 2000;79:155-69.
-
(2000)
Medicine (Baltimore)
, vol.79
, pp. 155-169
-
-
Winkelstein, J.A.1
Marino, M.C.2
Johnston Jr., R.B.3
Boyle, J.4
Curnutte, J.5
Gallin, J.I.6
-
23
-
-
1642575407
-
Crohn's-like ileo-colitis in patients affected by glycogen storage disease Ib: Two years' follow-up of patients with a wide spectrum of gastrointestinal signs
-
Melis D, Parenti G, Della Casa R, Sibilio M, Berni Canani R, Terrin G, et al. Crohn's-like ileo-colitis in patients affected by glycogen storage disease Ib: two years' follow-up of patients with a wide spectrum of gastrointestinal signs. Acta Paediatr 2003;92:1415-21.
-
(2003)
Acta Paediatr
, vol.92
, pp. 1415-1421
-
-
Melis, D.1
Parenti, G.2
Della Casa, R.3
Sibilio, M.4
Berni Canani, R.5
Terrin, G.6
-
24
-
-
0028972499
-
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
-
Hermiston ML, Gordon JI. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 1995;270:1203-7.
-
(1995)
Science
, vol.270
, pp. 1203-1207
-
-
Hermiston, M.L.1
Gordon, J.I.2
-
25
-
-
65749103989
-
Regulatory lymphocytes and intestinal inflammation
-
Izcue A, Coombes JL, Powrie F. Regulatory lymphocytes and intestinal inflammation. Annu Rev Immunol 2009;27:313-38.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 313-338
-
-
Izcue, A.1
Coombes, J.L.2
Powrie, F.3
-
26
-
-
33744804299
-
Metagenomic analysis of the human distal gut microbiome
-
Gill SR, Pop M, Deboy RT, Eckburg PB, Turnbaugh PJ, Samuel BS, et al. Metagenomic analysis of the human distal gut microbiome. Science 2006;312:1355-9.
-
(2006)
Science
, vol.312
, pp. 1355-1359
-
-
Gill, S.R.1
Pop, M.2
Deboy, R.T.3
Eckburg, P.B.4
Turnbaugh, P.J.5
Samuel, B.S.6
-
27
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, et al. A core gut microbiome in obese and lean twins. Nature 2009;457:480-4.
-
(2009)
Nature
, vol.457
, pp. 480-484
-
-
Turnbaugh, P.J.1
Hamady, M.2
Yatsunenko, T.3
Cantarel, B.L.4
Duncan, A.5
Ley, R.E.6
-
28
-
-
44649118583
-
Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases
-
Peterson DA, Frank DN, Pace NR, Gordon JI. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe 2008;3:417-27.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 417-427
-
-
Peterson, D.A.1
Frank, D.N.2
Pace, N.R.3
Gordon, J.I.4
-
29
-
-
67349250428
-
The gut microbiota shapes intestinal immune responses during health and disease
-
Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 2009;9:313-23.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 313-323
-
-
Round, J.L.1
Mazmanian, S.K.2
-
30
-
-
80054020840
-
Peripheral education of the immune system by colonic commensal microbiota
-
Lathrop SK, Bloom SM, Rao SM, Nutsch K, Lio CW, Santacruz N, et al. Peripheral education of the immune system by colonic commensal microbiota. Nature 2011;478:250-4.
-
(2011)
Nature
, vol.478
, pp. 250-254
-
-
Lathrop, S.K.1
Bloom, S.M.2
Rao, S.M.3
Nutsch, K.4
Lio, C.W.5
Santacruz, N.6
-
31
-
-
58549111588
-
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
-
Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci USA 2008;105:20858-63.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20858-20863
-
-
Vaishnava, S.1
Behrendt, C.L.2
Ismail, A.S.3
Eckmann, L.4
Hooper, L.V.5
-
32
-
-
0027215978
-
Expansion of alpha beta T-cell receptor-bearing intestinal intraepithelial lymphocytes after microbial colonization in germ-free mice and its independence from thymus
-
Umesaki Y, Setoyama H, Matsumoto S, Okada Y. Expansion of alpha beta T-cell receptor-bearing intestinal intraepithelial lymphocytes after microbial colonization in germ-free mice and its independence from thymus. Immunology 1993;79:32-7.
-
(1993)
Immunology
, vol.79
, pp. 32-37
-
-
Umesaki, Y.1
Setoyama, H.2
Matsumoto, S.3
Okada, Y.4
-
33
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal inflammatory disease
-
Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008;453:620-5.
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
34
-
-
53349173070
-
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
-
Ivanov II, Frutos Rde L, Manel N, Yoshinaga K, Rifkin DB, Sartor RB, et al. Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008;4:337-49.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 337-349
-
-
Ivanov, I.I.1
Frutos Rde, L.2
Manel, N.3
Yoshinaga, K.4
Rifkin, D.B.5
Sartor, R.B.6
-
35
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of type 1 diabetes
-
Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, et al. Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature 2008;455:1109-13.
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
Ley, R.E.2
Volchkov, P.Y.3
Stranges, P.B.4
Avanesyan, L.5
Stonebraker, A.C.6
-
36
-
-
34147095993
-
Clinical usefulness of probiotics in inflammatory bowel diseases
-
Mach T. Clinical usefulness of probiotics in inflammatory bowel diseases. J Physiol Pharmacol 2006;57:23-33.
-
(2006)
J Physiol Pharmacol
, vol.57
, pp. 23-33
-
-
Mach, T.1
-
37
-
-
1842430006
-
Bacterial invasion: The paradigms of enteroinvasive pathogens
-
Cossart P, Sansonetti PJ. Bacterial invasion: the paradigms of enteroinvasive pathogens. Science 2004;304:242-8.
-
(2004)
Science
, vol.304
, pp. 242-248
-
-
Cossart, P.1
Sansonetti, P.J.2
-
38
-
-
79952449393
-
Management of gut inflammation through the manipulation of intestinal dendritic cells and macrophages?
-
Bar-On L, Zigmond E, Jung S. Management of gut inflammation through the manipulation of intestinal dendritic cells and macrophages? Semin Immunol 2011;23:58-64.
-
(2011)
Semin Immunol
, vol.23
, pp. 58-64
-
-
Bar-On, L.1
Zigmond, E.2
Jung, S.3
-
39
-
-
79955110851
-
Immunoregulatory mechanisms of macrophage PPAR-γ in mice with experimental inflammatory bowel disease
-
Hontecillas R, Horne WT, Climent M, Guri AJ, Evans C, Zhang Y, et al. Immunoregulatory mechanisms of macrophage PPAR-γ in mice with experimental inflammatory bowel disease. Mucosal Immunol 2011;4:304-13.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 304-313
-
-
Hontecillas, R.1
Horne, W.T.2
Climent, M.3
Guri, A.J.4
Evans, C.5
Zhang, Y.6
-
40
-
-
0034005581
-
Role of cytokines in the pathogenesis of inflammatory bowel disease
-
Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annu Rev Med 2000;51:289-98.
-
(2000)
Annu Rev Med
, vol.51
, pp. 289-298
-
-
Papadakis, K.A.1
Targan, S.R.2
-
41
-
-
0031914778
-
Cytokines in inflammatory bowel disease
-
Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg 1998;22:382-9.
-
(1998)
World J Surg
, vol.22
, pp. 382-389
-
-
Rogler, G.1
Andus, T.2
-
42
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
Neurath MF, Fuss I, Kelsall BL, Stüber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995;182:1281-90.
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stüber, E.4
Strober, W.5
-
43
-
-
79955563439
-
Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases
-
Strober W, Fuss IJ. Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 2011;140:1756-67.
-
(2011)
Gastroenterology
, vol.140
, pp. 1756-1767
-
-
Strober, W.1
Fuss, I.J.2
-
44
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, et al. Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med 2004;351:2069-79.
-
(2004)
N Engl J Med
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
Elson, C.O.4
Sandborn, W.J.5
Present, D.6
-
45
-
-
53049091561
-
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN, Scherl E, Fleisher MR, Katz S, et al. A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 2008;135:1130-41.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
Scherl, E.4
Fleisher, M.R.5
Katz, S.6
-
46
-
-
0031573593
-
A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease
-
Plevy SE, Landers CJ, Prehn J, Carramanzana NM, Deem RL, Shealy D, et al. A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease. J Immunol 1997;159:6276-82.
-
(1997)
J Immunol
, vol.159
, pp. 6276-6282
-
-
Plevy, S.E.1
Landers, C.J.2
Prehn, J.3
Carramanzana, N.M.4
Deem, R.L.5
Shealy, D.6
-
47
-
-
0027984036
-
Human APC gene expression in rodent colonic epithelium in vivo using liposomal gene delivery
-
Westbrook CA, Chmura SJ, Arenas RB, Kim SY, Otto G. Human APC gene expression in rodent colonic epithelium in vivo using liposomal gene delivery. Hum Mol Genet 1994;3:2005-10.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 2005-2010
-
-
Westbrook, C.A.1
Chmura, S.J.2
Arenas, R.B.3
Kim, S.Y.4
Otto, G.5
-
48
-
-
0030179370
-
Tumor inhibitory activity of anti-ras ribozymes delivered by retroviral gene transfer
-
Li M, Lonial H, Citarella R, Lindh D, Colina L, Kramer R. Tumor inhibitory activity of anti-ras ribozymes delivered by retroviral gene transfer. Cancer Gene Ther 1996;3:221-9.
-
(1996)
Cancer Gene Ther
, vol.3
, pp. 221-229
-
-
Li, M.1
Lonial, H.2
Citarella, R.3
Lindh, D.4
Colina, L.5
Kramer, R.6
-
49
-
-
0031721136
-
Peroral gene therapy of lactose intolerance using an adeno-associated virus vector
-
During MJ, Xu R, Young D, Kaplitt MG, Sherwin RS, Leone P. Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nat Med 1998;4:1131-5.
-
(1998)
Nat Med
, vol.4
, pp. 1131-1135
-
-
During, M.J.1
Xu, R.2
Young, D.3
Kaplitt, M.G.4
Sherwin, R.S.5
Leone, P.6
-
50
-
-
0033055144
-
Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure
-
Wirtz S, Galle PR, Neurath MF. Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure. Gut 1999;44:800-7.
-
(1999)
Gut
, vol.44
, pp. 800-807
-
-
Wirtz, S.1
Galle, P.R.2
Neurath, M.F.3
-
51
-
-
17344368195
-
Adenovirus-mediated transduction of intestinal cells in vivo
-
Foreman PK, Wainwright MJ, Alicke B, Kovesdi I, Wickham TJ, Smith JG, et al. Adenovirus-mediated transduction of intestinal cells in vivo. Hum Gene Ther 1998;9:1313-21.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1313-1321
-
-
Foreman, P.K.1
Wainwright, M.J.2
Alicke, B.3
Kovesdi, I.4
Wickham, T.J.5
Smith, J.G.6
-
52
-
-
0034600789
-
Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid: TGF-beta1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation
-
Kitani A, Fuss IJ, Nakamura K, Schwartz OM, Usui T, Strober W. Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid: TGF-beta1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation. J Exp Med 2000;192:41-52.
-
(2000)
J Exp Med
, vol.192
, pp. 41-52
-
-
Kitani, A.1
Fuss, I.J.2
Nakamura, K.3
Schwartz, O.M.4
Usui, T.5
Strober, W.6
-
53
-
-
79951596110
-
Salmonella-mediated gene therapy in experimental colitis in mice
-
Palffy R, Gardlik R, Behuliak M, Jani P, Balakova D, Kadasi L, et al. Salmonella-mediated gene therapy in experimental colitis in mice. Exp Biol Med (Maywood) 2011;236:177-83.
-
(2011)
Exp Biol Med (Maywood)
, vol.236
, pp. 177-183
-
-
Palffy, R.1
Gardlik, R.2
Behuliak, M.3
Jani, P.4
Balakova, D.5
Kadasi, L.6
-
54
-
-
38849166053
-
Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target
-
Peer D, Park EJ, Morishita Y, Carman CV, Shimaoka M. Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science 2008;319:627-30.
-
(2008)
Science
, vol.319
, pp. 627-630
-
-
Peer, D.1
Park, E.J.2
Morishita, Y.3
Carman, C.V.4
Shimaoka, M.5
-
55
-
-
79952464608
-
Role of sensory neurons in colitis - Increasing evidence for a neuro-immune link in the gut
-
Engel MA, Becker C, Reeh PW, Neurath MF. Role of sensory neurons in colitis - increasing evidence for a neuro-immune link in the gut. Inflamm Bowel Dis 2011;17:1030-3.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1030-1033
-
-
Engel, M.A.1
Becker, C.2
Reeh, P.W.3
Neurath, M.F.4
-
56
-
-
80053600154
-
TRPA1 and substance P mediate colitis in mice
-
Engel MA, Leffler A, Niedermirtl F, Babes A, Zimmermann K, Filipovic' MR, et al. TRPA1 and substance P mediate colitis in mice. Gastroenterology 2011;141:1346-58.
-
(2011)
Gastroenterology
, vol.141
, pp. 1346-1358
-
-
Engel, M.A.1
Leffler, A.2
Niedermirtl, F.3
Babes, A.4
Zimmermann, K.5
Filipovic, M.R.6
-
57
-
-
0032933192
-
SR140333, a substance P receptor antagonist, influences morphological and motor changes in rat experimental colitis
-
Di Sebastiano P, Grossi L, Di Mola FF, Angelucci D, Friess H, Marzio L, et al. SR140333, a substance P receptor antagonist, influences morphological and motor changes in rat experimental colitis. Dig Dis Sci 1999;44:439-44.
-
(1999)
Dig Dis Sci
, vol.44
, pp. 439-444
-
-
Di Sebastiano, P.1
Grossi, L.2
Di Mola, F.F.3
Angelucci, D.4
Friess, H.5
Marzio, L.6
-
58
-
-
0033637090
-
NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats
-
Stucchi AF, Shofer S, Leeman S, Materne O, Beer E, McClung J, et al. NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol 2000;279:1298-306.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
, pp. 1298-1306
-
-
Stucchi, A.F.1
Shofer, S.2
Leeman, S.3
Materne, O.4
Beer, E.5
McClung, J.6
-
59
-
-
83855160826
-
Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis
-
Engel MA, Khalil M, Siklosi N, Mueller-Tribbensee SM, Neuhuber WL, Neurath MF, et al. Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis. Dig Liver Dis 2012;44:24-9.
-
(2012)
Dig Liver Dis
, vol.44
, pp. 24-29
-
-
Engel, M.A.1
Khalil, M.2
Siklosi, N.3
Mueller-Tribbensee, S.M.4
Neuhuber, W.L.5
Neurath, M.F.6
-
60
-
-
0027378031
-
Involvement of calcitonin gene-related peptide in rat experimental colitis
-
Evangelista S, Tramontana M. Involvement of calcitonin gene-related peptide in rat experimental colitis. J Physiol Paris 1993;87:277-80.
-
(1993)
J Physiol Paris
, vol.87
, pp. 277-280
-
-
Evangelista, S.1
Tramontana, M.2
-
61
-
-
34547104411
-
Role of calcitonin receptor-like receptor in colonic motility and inflammation
-
Clifton MS, Hoy JJ, Chang J, Idumalla PS, Fakhruddin H, Grady EF, et al. Role of calcitonin receptor-like receptor in colonic motility and inflammation. Am J Physiol Gastrointest Liver Physiol 2007;293:36-44.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
, pp. 36-44
-
-
Clifton, M.S.1
Hoy, J.J.2
Chang, J.3
Idumalla, P.S.4
Fakhruddin, H.5
Grady, E.F.6
-
62
-
-
44349134427
-
The neuropeptide calcitonin generelated peptide (CGRP) stimulates T cell migration into collagen matrices
-
Talme T, Liu Z, Sundqvist KG. The neuropeptide calcitonin generelated peptide (CGRP) stimulates T cell migration into collagen matrices. J Neuroimmunol 2008;196:60-6.
-
(2008)
J Neuroimmunol
, vol.196
, pp. 60-66
-
-
Talme, T.1
Liu, Z.2
Sundqvist, K.G.3
-
63
-
-
51449100808
-
Neurotransmitters activate T-cells and elicit crucial functions via neurotransmitter receptors
-
Levite M. Neurotransmitters activate T-cells and elicit crucial functions via neurotransmitter receptors. Curr Opin Pharmacol 2008;8:460-71.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 460-471
-
-
Levite, M.1
-
64
-
-
16644364367
-
Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis
-
Fujino K, Takami Y, De La Fuente SG, Ludwig KA, Mantyh CR. Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis. J Gastrointest Surg 2004;8:842-7.
-
(2004)
J Gastrointest Surg
, vol.8
, pp. 842-847
-
-
Fujino, K.1
Takami, Y.2
De La Fuente, S.G.3
Ludwig, K.A.4
Mantyh, C.R.5
-
65
-
-
0037624584
-
Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats
-
Kihara N, De La Fuente SG, Fujino K, Takahashi T, Pappas TN, Mantyh CR. Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats. Gut 2003;52:713-9.
-
(2003)
Gut
, vol.52
, pp. 713-719
-
-
Kihara, N.1
De La Fuente, S.G.2
Fujino, K.3
Takahashi, T.4
Pappas, T.N.5
Mantyh, C.R.6
-
66
-
-
77955174633
-
The role of transient receptor potential vanilloid 1 (TRPV1) receptors in dextran sulfate-induced colitis in mice
-
Szitter I, Pozsgai G, Sandor K, Elekes K, Kemeny A, Perkecz A, et al. The role of transient receptor potential vanilloid 1 (TRPV1) receptors in dextran sulfate-induced colitis in mice. J Mol Neurosci 2010;42:80-8.
-
(2010)
J Mol Neurosci
, vol.42
, pp. 80-88
-
-
Szitter, I.1
Pozsgai, G.2
Sandor, K.3
Elekes, K.4
Kemeny, A.5
Perkecz, A.6
-
67
-
-
32044436722
-
Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid induced colitis
-
Massa F, Sibaev A, Marsicano G, Blaudzun H, Storr M, Lutz B. Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid induced colitis. J Mol Med 2006;84:142-6.
-
(2006)
J Mol Med
, vol.84
, pp. 142-146
-
-
Massa, F.1
Sibaev, A.2
Marsicano, G.3
Blaudzun, H.4
Storr, M.5
Lutz, B.6
-
68
-
-
67049119907
-
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
-
Caceres AI, Brackmann M, Elia MD, Bessac BF, Del Camino D, D'Amours M, et al. A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci USA 2009;106:9099-104.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9099-9104
-
-
Caceres, A.I.1
Brackmann, M.2
Elia, M.D.3
Bessac, B.F.4
Del Camino, D.5
D'Amours, M.6
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