메뉴 건너뛰기




Volumn 30, Issue 5, 2012, Pages 1849-1864

The effect of a novel frizzled 8-related antiproliferative factor on in vitro carcinoma and melanoma cell proliferation and invasion

Author keywords

Antiproliferative factor; Carcinoma; HB EGF; Invasion; Melanoma; MMP2

Indexed keywords

ASIALYLATED SYNTHETIC ANTIPROLIFERATIVE FACTOR DERIVATIVE; FRIZZLED PROTEIN; GELATINASE A; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84867774972     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-011-9746-x     Document Type: Article
Times cited : (4)

References (81)
  • 3
    • 20444453658 scopus 로고    scopus 로고
    • Update on chemotherapy for advanced bladder cancer
    • 15947569 1:CAS:528:DC%2BD2MXkvFSqtLo%3D
    • Rosenberg JE, Carroll PR, Small EJ (2005) Update on chemotherapy for advanced bladder cancer. J Urol 174:14-20
    • (2005) J Urol , vol.174 , pp. 14-20
    • Rosenberg, J.E.1    Carroll, P.R.2    Small, E.J.3
  • 5
    • 67650401369 scopus 로고    scopus 로고
    • Bladder cancer
    • 10.1016/So140-6736(09)60491-60498 19520422 1:CAS:528:DC%2BD1MXos12ru7g%3D
    • Kaufman DS, Shipley WU, Feldman AS (2009) Bladder cancer. Lancet 374:239-249. doi: 10.1016/So140-6736(09)60491-60498
    • (2009) Lancet , vol.374 , pp. 239-249
    • Kaufman, D.S.1    Shipley, W.U.2    Feldman, A.S.3
  • 7
    • 33745684404 scopus 로고    scopus 로고
    • Mechanisms of disease: Melanoma
    • 16822996 1:CAS:528:DC%2BD28Xms1ChsLo%3D
    • Miller AJ, Mihm MC Jr (2006) Mechanisms of disease: Melanoma. New Engl J Med 355:51-65
    • (2006) New Engl J Med , vol.355 , pp. 51-65
    • Miller, A.J.1    Mihm, Jr.M.C.2
  • 8
    • 0038574720 scopus 로고    scopus 로고
    • E-cadherin involved in inactivation of WNT/beta-catenin signalling in urothelial carcinoma and normal urothelial cells
    • 12799639 1:CAS:528:DC%2BD3sXksVKjurw%3D
    • Thievessen I, Seifert HH, Swiatkowski S, Flori AR, Schulz WA (2003) E-cadherin involved in inactivation of WNT/beta-catenin signalling in urothelial carcinoma and normal urothelial cells. Br J Cancer 88:1932-1938
    • (2003) Br J Cancer , vol.88 , pp. 1932-1938
    • Thievessen, I.1    Seifert, H.H.2    Swiatkowski, S.3    Flori, A.R.4    Schulz, W.A.5
  • 9
    • 25144451812 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition (EMT) and colorectal cancer progression
    • 15846061 1:CAS:528:DC%2BD28Xitl2rsLc%3D
    • Bates RC, Mercurio AM (2005) The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. Cancer Biol Ther 4:365-370
    • (2005) Cancer Biol Ther , vol.4 , pp. 365-370
    • Bates, R.C.1    Mercurio, A.M.2
  • 10
    • 0034852853 scopus 로고    scopus 로고
    • The E-cadherin/catenin complex: An important gatekeeper in breast cancer tumorigenesis and malignant progression
    • Berx G, Van Roy F (2001) The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. Breast Cancer Res 3:389-393
    • (2001) Breast Cancer Res , vol.3 , pp. 389-393
    • Berx, G.1    Van Roy, F.2
  • 11
    • 0030003483 scopus 로고    scopus 로고
    • Loss of human E-cadherin (ECD) correlated with invasiveness of transitional cell cancer in the renal pelvis, ureter and urinary bladder
    • 8616803 1:CAS:528:DyaK28XisFWhsbk%3D
    • Wakatsuki S, Watanabe R, Saito K, Saito T, Katagiri A, Sato S, Tomita Y (1996) Loss of human E-cadherin (ECD) correlated with invasiveness of transitional cell cancer in the renal pelvis, ureter and urinary bladder. Cancer Lett 103:11-17
    • (1996) Cancer Lett , vol.103 , pp. 11-17
    • Wakatsuki, S.1    Watanabe, R.2    Saito, K.3    Saito, T.4    Katagiri, A.5    Sato, S.6    Tomita, Y.7
  • 12
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • 16098727 1:CAS:528:DC%2BD2MXhtVWnsb7L
    • Huber MA, Kraut N, Beug H (2005) Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 17:548-558
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 13
    • 34250174504 scopus 로고    scopus 로고
    • The role of epithelial-mesenchymal transition in cancer pathology
    • 17558857 1:CAS:528:DC%2BD2sXmt1ant7o%3D
    • Guarino M, Rubino B, Ballabio G (2007) The role of epithelial-mesenchymal transition in cancer pathology. Pathology 39:305-318
    • (2007) Pathology , vol.39 , pp. 305-318
    • Guarino, M.1    Rubino, B.2    Ballabio, G.3
  • 15
    • 51349098887 scopus 로고    scopus 로고
    • Co-targeting survival signalling pathways in cancer
    • 18725993 1:CAS:528:DC%2BD1cXhtV2isbzM
    • Grant S (2008) Co-targeting survival signalling pathways in cancer. J Clin Invest 118:3003-3006
    • (2008) J Clin Invest , vol.118 , pp. 3003-3006
    • Grant, S.1
  • 17
    • 34748866686 scopus 로고    scopus 로고
    • Signaling pathways in cancer and embryonic stem cells
    • 17873377 1:CAS:528:DC%2BD2sXhtVent7nO
    • Dreesen O, Brivanlou AH (2007) Signaling pathways in cancer and embryonic stem cells. Stem Cell Rev 3:7-17
    • (2007) Stem Cell Rev , vol.3 , pp. 7-17
    • Dreesen, O.1    Brivanlou, A.H.2
  • 18
    • 35348993675 scopus 로고    scopus 로고
    • New approach to cancer therapy: Heparin binding-epidermal growth factor-like growth factor as a novel targeting molecule
    • 17970033 1:CAS:528:DC%2BD2sXhtlSltL%2FE
    • Miyamoto S, Yagi H, Yotsumoto F, Horiuchi S, Yoshizato T, Kawarabayashi T, Kuroki M, Mekada E (2007) New approach to cancer therapy: heparin binding-epidermal growth factor-like growth factor as a novel targeting molecule. Anticancer Res 27:3713-3721
    • (2007) Anticancer Res , vol.27 , pp. 3713-3721
    • Miyamoto, S.1    Yagi, H.2    Yotsumoto, F.3    Horiuchi, S.4    Yoshizato, T.5    Kawarabayashi, T.6    Kuroki, M.7    Mekada, E.8
  • 19
  • 20
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulators of the tumor microenvironment
    • 10.1016/j.cell.2010.03.015 20371345 1:CAS:528:DC%2BC3cXlsVSgtb4%3D
    • Kessenbrock K, Plaks V, Werb Z (2010) Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141:52-67. doi: 10.1016/j.cell.2010.03.015
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 21
    • 73649096235 scopus 로고    scopus 로고
    • Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation
    • 19887570 1:CAS:528:DC%2BC3cXls1Cqug%3D%3D
    • Sonderegger S, Haslinger P, Sabri A, Leisser C, Otten JV, Fiala C, Knöfler M (2010) Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation. Endocrinology 151:211-220
    • (2010) Endocrinology , vol.151 , pp. 211-220
    • Sonderegger, S.1    Haslinger, P.2    Sabri, A.3    Leisser, C.4    Otten, J.V.5    Fiala, C.6    Knöfler, M.7
  • 22
    • 0037462733 scopus 로고    scopus 로고
    • Proximal events in signaling by plasma membrane estrogen receptors
    • 12421825 1:CAS:528:DC%2BD3sXksFaktw%3D%3D
    • Razandi M, Pedram A, Park ST, Levin ER (2003) Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem 278:2701-2712
    • (2003) J Biol Chem , vol.278 , pp. 2701-2712
    • Razandi, M.1    Pedram, A.2    Park, S.T.3    Levin, E.R.4
  • 23
    • 63649143625 scopus 로고    scopus 로고
    • Tissue biomarkers for prognosis in cutaneous melanoma: A systematic review and meta-analysis
    • 19318635
    • Gould Rothberg BE, Bracken MB, Rimm DL (2009) Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst 101:452-474
    • (2009) J Natl Cancer Inst , vol.101 , pp. 452-474
    • Gould Rothberg, B.E.1    Bracken, M.B.2    Rimm, D.L.3
  • 24
    • 0032055870 scopus 로고    scopus 로고
    • Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer
    • 9529029 1:STN:280:DyaK1c7oslykug%3D%3D
    • Kanayama H, Yokota K, Kurokawa Y, Murakami Y, Nishitani M, Kagawa S (1998) Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer. Cancer 82:1359-1366
    • (1998) Cancer , vol.82 , pp. 1359-1366
    • Kanayama, H.1    Yokota, K.2    Kurokawa, Y.3    Murakami, Y.4    Nishitani, M.5    Kagawa, S.6
  • 26
    • 0035344064 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2
    • 11295046 1:CAS:528:DC%2BD3MXjsVSisLk%3D
    • Saitoh T, Hirai M, Katoh M (2001) Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2. Int J Oncol 18:991-996
    • (2001) Int J Oncol , vol.18 , pp. 991-996
    • Saitoh, T.1    Hirai, M.2    Katoh, M.3
  • 28
    • 34547096269 scopus 로고    scopus 로고
    • P53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells
    • 17628545 1:CAS:528:DC%2BD2sXotlSmu78%3D
    • Kim J, Keay SK, Dimitrakov JD, Freeman MR (2007) p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells. FEBS Lett 581:3795-3799
    • (2007) FEBS Lett , vol.581 , pp. 3795-3799
    • Kim, J.1    Keay, S.K.2    Dimitrakov, J.D.3    Freeman, M.R.4
  • 29
    • 0041302205 scopus 로고    scopus 로고
    • Changes in human bladder cell gene expression associated with interstitial cystitis or antiproliferative factor treatment
    • 12847144 1:CAS:528:DC%2BD3sXnsFSisrs%3D
    • Keay S, Seillier-Moiseiwitsch F, Zhang C-O, Chai TC, Zhang J (2003) Changes in human bladder cell gene expression associated with interstitial cystitis or antiproliferative factor treatment. Physiol Genomics 14:107-115
    • (2003) Physiol Genomics , vol.14 , pp. 107-115
    • Keay, S.1    Seillier-Moiseiwitsch, F.2    Zhang, C.-O.3    Chai, T.C.4    Zhang, J.5
  • 30
    • 78651408943 scopus 로고    scopus 로고
    • Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells
    • 21143984 1:CAS:528:DC%2BC3cXhs1amsb7L
    • Shahjee H, Koch K, Guo L, Zhang C-O, Keay S (2010) Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells. J Exp Clin Cancer Res 29:160-170
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 160-170
    • Shahjee, H.1    Koch, K.2    Guo, L.3    Zhang, C.-O.4    Keay, S.5
  • 31
    • 59249107643 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen-activated protein kinase pathway activation
    • 18990151 1:CAS:528:DC%2BD1MXjslamt7k%3D
    • Kim J, Keay SK, Freeman MR (2009) Heparin-binding epidermal growth factor-like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen-activated protein kinase pathway activation. BJU Int 103:541-546
    • (2009) BJU Int , vol.103 , pp. 541-546
    • Kim, J.1    Keay, S.K.2    Freeman, M.R.3
  • 32
    • 0033763259 scopus 로고    scopus 로고
    • Bladder epithelial cells from interstitial cystitis patients produce an inhibitor of HB-EGF production
    • 11061938 1:CAS:528:DC%2BD3cXos1ymt78%3D
    • Keay S, Kleinberg M, Zhang C-O, Hise MK, Warren JW (2000) Bladder epithelial cells from interstitial cystitis patients produce an inhibitor of HB-EGF production. J Urol 164:2112-2118
    • (2000) J Urol , vol.164 , pp. 2112-2118
    • Keay, S.1    Kleinberg, M.2    Zhang, C.-O.3    Hise, M.K.4    Warren, J.W.5
  • 33
    • 53549113970 scopus 로고    scopus 로고
    • Structure-activity relationship studies for the peptide portion of the bladder epithelial cell antiproliferative factor from interstitial cystitis patients
    • 18788730 1:CAS:528:DC%2BD1cXhtFelt73O
    • Kaczmarek P, Keay SK, Tocci GM, Koch KR, Zhang C-O, Barchi JJ Jr, Grkovic D, Guo L, Michejda CJ (2008) Structure-activity relationship studies for the peptide portion of the bladder epithelial cell antiproliferative factor from interstitial cystitis patients. J Med Chem 51:5974-5983
    • (2008) J Med Chem , vol.51 , pp. 5974-5983
    • Kaczmarek, P.1    Keay, S.K.2    Tocci, G.M.3    Koch, K.R.4    Zhang, C.-O.5    Barchi, Jr.J.J.6    Grkovic, D.7    Guo, L.8    Michejda, C.J.9
  • 34
    • 65249135965 scopus 로고    scopus 로고
    • Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling
    • 19144824 1:CAS:528:DC%2BD1MXlsFyis7g%3D
    • Planey SL, Keay SK, Zhang CO, Zacharias DA (2009) Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling. Mol Biol Cell 20:1454-1463
    • (2009) Mol Biol Cell , vol.20 , pp. 1454-1463
    • Planey, S.L.1    Keay, S.K.2    Zhang, C.O.3    Zacharias, D.A.4
  • 35
    • 33644831779 scopus 로고    scopus 로고
    • E-cadherin immunoreactivity correlates with recurrence and progression of minimally invasive transitional cell carcinomas of the urinary bladder
    • 16142373 1:CAS:528:DC%2BD2MXhtFegt7bI
    • Mahnken A, Kausch I, Feller AC, Kruger S (2005) E-cadherin immunoreactivity correlates with recurrence and progression of minimally invasive transitional cell carcinomas of the urinary bladder. Oncol Rep 14:1065-1070
    • (2005) Oncol Rep , vol.14 , pp. 1065-1070
    • Mahnken, A.1    Kausch, I.2    Feller, A.C.3    Kruger, S.4
  • 36
    • 33645785631 scopus 로고    scopus 로고
    • The prognostic value of E-cadherin, alpha-, beta-, and gamma-catenin in urothelial cancer of the upper urinary tract
    • 16426728 1:CAS:528:DC%2BD28Xlt1ejsLk%3D
    • Kashibuchi K, Tomita K, Schalken JA, Kume H, Yamaguchi T, Muto S, Horie S, Kitamura T (2006) The prognostic value of E-cadherin, alpha-, beta-, and gamma-catenin in urothelial cancer of the upper urinary tract. Eur Urol 49:839-845
    • (2006) Eur Urol , vol.49 , pp. 839-845
    • Kashibuchi, K.1    Tomita, K.2    Schalken, J.A.3    Kume, H.4    Yamaguchi, T.5    Muto, S.6
  • 38
    • 0035035986 scopus 로고    scopus 로고
    • P53 in bladder cancer: Mechanism of action, prognostic value, and target for therapy
    • 11337281 1:STN:280:DC%2BD3M3ms1Gitw%3D%3D
    • Slaton JW, Benedict WF, Dinney CP (2001) p53 in bladder cancer: mechanism of action, prognostic value, and target for therapy. Urology 57:852-859
    • (2001) Urology , vol.57 , pp. 852-859
    • Slaton, J.W.1    Benedict, W.F.2    Dinney, C.P.3
  • 39
    • 0035881981 scopus 로고    scopus 로고
    • A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients
    • 11507076
    • Thogersen VB, Sorensen BS, Poulsen SS, Orntoft TF, Wolf H, Nexo E (2001) A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients. Cancer Res 61:6227-6233
    • (2001) Cancer Res , vol.61 , pp. 6227-6233
    • Thogersen, V.B.1    Sorensen, B.S.2    Poulsen, S.S.3    Orntoft, T.F.4    Wolf, H.5    Nexo, E.6
  • 40
    • 0027384917 scopus 로고
    • Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion
    • 8221672 1:CAS:528:DyaK2cXltFequw%3D%3D
    • Davies B, Waxman J, Wasan H, Abel P, Williams G, Krausz T, Neal D, Thomas D, Hanby A, Balkwill F (1993) Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion. Cancer Res 53:5365-5369
    • (1993) Cancer Res , vol.53 , pp. 5365-5369
    • Davies, B.1    Waxman, J.2    Wasan, H.3
  • 41
    • 77957288035 scopus 로고    scopus 로고
    • Expanding therapeutic targets in bladder cancer: The PI3K/Akt/mTOR pathway
    • 20661228 1:CAS:528:DC%2BC3cXht1WmtbvK
    • Ching CB, Hansel DE (2010) Expanding therapeutic targets in bladder cancer: the PI3K/Akt/mTOR pathway. Lab Invest 90:1406-1414
    • (2010) Lab Invest , vol.90 , pp. 1406-1414
    • Ching, C.B.1    Hansel, D.E.2
  • 43
    • 0036897242 scopus 로고    scopus 로고
    • Molecular profiling of bladder cancer using cDNA microarrays: Defining histogenesis and biological phenotypes
    • 12460915 1:CAS:528:DC%2BD38XpsVahsb8%3D
    • Sanchez-Carbayo M, Socci ND, Charytonowicz E, Lu M, Prystowsky M, Childs G, Cordon-Cardo C (2002) Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes. Cancer Res 62:6973-6980
    • (2002) Cancer Res , vol.62 , pp. 6973-6980
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Charytonowicz, E.3    Lu, M.4    Prystowsky, M.5    Childs, G.6    Cordon-Cardo, C.7
  • 44
    • 0024326112 scopus 로고
    • Routine excretory urography in follow-up of superficial transitional cell carcinoma of bladder
    • 2508289 1:STN:280:DyaK3c%2FitVOmtw%3D%3D
    • Smith H, Weaver D, Barjenbruch O, Weinstein S, Ross G Jr (1989) Routine excretory urography in follow-up of superficial transitional cell carcinoma of bladder. Urology 34:193-196
    • (1989) Urology , vol.34 , pp. 193-196
    • Smith, H.1    Weaver, D.2    Barjenbruch, O.3    Weinstein, S.4    Ross, Jr.G.5
  • 45
    • 72149114869 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase/Akt signaling pathway and kidney cancer, and the therapeutic potential of phosphatidylinositol-3-kinase/Akt inhibitors
    • 19836781 1:CAS:528:DC%2BD1MXhsFKjsrvN
    • Porta C, Figlin RA (2009) Phosphatidylinositol-3-kinase/Akt signaling pathway and kidney cancer, and the therapeutic potential of phosphatidylinositol-3-kinase/Akt inhibitors. J Urol 182:2569-2577
    • (2009) J Urol , vol.182 , pp. 2569-2577
    • Porta, C.1    Figlin, R.A.2
  • 46
    • 34347244544 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in kidney cancer
    • 17555396 1:CAS:528:DC%2BD2sXmtFOhtbs%3D
    • Park JY, Lin PY, Weiss RH (2007) Targeting the PI3K-Akt pathway in kidney cancer. Expert Rev Anticancer Ther 7:863-870
    • (2007) Expert Rev Anticancer Ther , vol.7 , pp. 863-870
    • Park, J.Y.1    Lin, P.Y.2    Weiss, R.H.3
  • 47
    • 45549085281 scopus 로고    scopus 로고
    • Molecular targeting agents in renal cell carcinoma: Present strategies and future perspectives
    • 18473855 1:CAS:528:DC%2BD1cXmslKku7c%3D
    • Bjelogrlic SK, Radulovic S, Babovic N (2008) Molecular targeting agents in renal cell carcinoma: present strategies and future perspectives. Curr Pharm Des 14:1058-1077
    • (2008) Curr Pharm des , vol.14 , pp. 1058-1077
    • Bjelogrlic, S.K.1    Radulovic, S.2    Babovic, N.3
  • 48
    • 52649131951 scopus 로고    scopus 로고
    • Molecular origins of cancer - Lung cancer
    • 18815398 1:CAS:528:DC%2BD1cXhtFKjt7bM
    • Herbst RS, Hermach JV, Lippman RM (2008) Molecular origins of cancer - lung cancer. N Engl J Med 359:1367-1380
    • (2008) N Engl J Med , vol.359 , pp. 1367-1380
    • Herbst, R.S.1    Hermach, J.V.2    Lippman, R.M.3
  • 49
    • 84878881288 scopus 로고    scopus 로고
    • Lung Carcinoma: Tumors of the Lungs
    • online edition
    • Lung Carcinoma: Tumors of the Lungs. Merck manual professional edition, online edition. http://www.merck.com/mmpe/sec05/ch062/ch062b.html#sec05-ch062- ch062b-1405
    • Merck Manual Professional Edition
  • 50
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death, and cancer
    • 12719720 1:CAS:528:DC%2BD3sXjt1GjsLg%3D
    • Oren M (2003) Decision making by p53: life, death, and cancer. Cell Death Differ 10:431-442
    • (2003) Cell Death Differ , vol.10 , pp. 431-442
    • Oren, M.1
  • 51
    • 0038696363 scopus 로고    scopus 로고
    • Clinical implication of p53 mutation in lung cancer
    • 1:CAS:528:DC%2BD3sXks1Gqtrs%3D
    • Campling BG, El-Deiry WS (2003) Clinical implication of p53 mutation in lung cancer. Mol Biotech 24:141-156
    • (2003) Mol Biotech , vol.24 , pp. 141-156
    • Campling, B.G.1    El-Deiry, W.S.2
  • 52
    • 42149091756 scopus 로고    scopus 로고
    • Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer
    • 18366007
    • Leinonen T, Pirinen R, Böhm J, Johansson R, Kosma VM (2008) Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer. Histol Histopathol 23:693-700
    • (2008) Histol Histopathol , vol.23 , pp. 693-700
    • Leinonen, T.1    Pirinen, R.2    Böhm, J.3    Johansson, R.4    Kosma, V.M.5
  • 53
    • 0033931447 scopus 로고    scopus 로고
    • The p53 tumor suppressor gene: From molecular biology to clinical investigation
    • 10911910 1:CAS:528:DC%2BD3cXlsVOjt74%3D
    • Soussi T (2000) The p53 tumor suppressor gene: from molecular biology to clinical investigation. Ann NY Acad Sci 910:121-137
    • (2000) Ann NY Acad Sci , vol.910 , pp. 121-137
    • Soussi, T.1
  • 55
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • 17604717 1:CAS:528:DC%2BD2sXotV2hs7g%3D
    • Manning BD, Cantley LC (2007) AKT/PKB signaling: navigating downstream. Cell 129:1261-1274
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 57
    • 0027214689 scopus 로고
    • An association between the risk of cancer and mutations in the HRAS1 minisatellite locus
    • 8336750 1:STN:280:DyaK3szjtVeitQ%3D%3D
    • Krontiris TG, Devlin B, Karp DD, Robert NJ, Risch N (1993) An association between the risk of cancer and mutations in the HRAS1 minisatellite locus. N Engl J Med 329:517-523
    • (1993) N Engl J Med , vol.329 , pp. 517-523
    • Krontiris, T.G.1    Devlin, B.2    Karp, D.D.3    Robert, N.J.4    Risch, N.5
  • 58
    • 33644860571 scopus 로고    scopus 로고
    • Tumor suppressor genes in breast cancer: The gatekeepers and the caretakers
    • 16468415 1:CAS:528:DC%2BD28Xjs1ekug%3D%3D
    • Oliveira AM, Ross JS, Fletcher JA (2005) Tumor suppressor genes in breast cancer: the gatekeepers and the caretakers. Am J Clin Pathol 124(Suppl):S16-S28
    • (2005) Am J Clin Pathol , vol.124 , Issue.SUPPL.
    • Oliveira, A.M.1    Ross, J.S.2    Fletcher, J.A.3
  • 59
    • 63449131596 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 involvement in breast cancer progression: A mini-review
    • Jezierska A, Motyl T (2009) Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review. Med Sci Monit 15:RA32-40
    • (2009) Med Sci Monit , vol.15
    • Jezierska, A.1    Motyl, T.2
  • 60
    • 79955555659 scopus 로고    scopus 로고
    • Targeting the phosphatidylinositol 3-kinase signaling pathway in breast cancer
    • 21406469 1:CAS:528:DC%2BC3MXhtlSktrrL
    • Hernandez-Aya LF, Gonzalez-Angulo AM (2011) Targeting the phosphatidylinositol 3-kinase signaling pathway in breast cancer. Oncologist 16:404-414
    • (2011) Oncologist , vol.16 , pp. 404-414
    • Hernandez-Aya, L.F.1    Gonzalez-Angulo, A.M.2
  • 63
    • 34247111871 scopus 로고    scopus 로고
    • Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer
    • 17377415 1:CAS:528:DC%2BD2sXktFemt7c%3D
    • Juuti A, Lundin J, Nordling S, Louhimo J, Haglund C (2006) Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer. Oncology 71:61-68
    • (2006) Oncology , vol.71 , pp. 61-68
    • Juuti, A.1    Lundin, J.2    Nordling, S.3    Louhimo, J.4    Haglund, C.5
  • 64
    • 77954676046 scopus 로고    scopus 로고
    • Molecular mechanism of pancreatic cancer - Understanding proliferation, invasion, and metastasis
    • 20237938
    • Mihaljevic AL, Michalski CW, Friess H, Kleeff J (2010) Molecular mechanism of pancreatic cancer - understanding proliferation, invasion, and metastasis. Langenbecks Arch Surg 395:295-308
    • (2010) Langenbecks Arch Surg , vol.395 , pp. 295-308
    • Mihaljevic, A.L.1    Michalski, C.W.2    Friess, H.3    Kleeff, J.4
  • 65
    • 77952561732 scopus 로고    scopus 로고
    • Networks and pathways in pigmentation, health, and disease
    • 20161540 1:CAS:528:DC%2BC3cXmtVSrt7Y%3D
    • Baxter LL, Loftus SK, Pavan WJ (2009) Networks and pathways in pigmentation, health, and disease. Wiley Interdiscip Rev Syst Biol Med 1:359-371
    • (2009) Wiley Interdiscip Rev Syst Biol Med , vol.1 , pp. 359-371
    • Baxter, L.L.1    Loftus, S.K.2    Pavan, W.J.3
  • 66
    • 0026076465 scopus 로고
    • Keratin and carcinoembryonic antigen (CEA) in human melanoma cells
    • 1:STN:280:DyaK38%2FnsVaisA%3D%3D
    • Om A, Ghose T, Rowden G (1991) Keratin and carcinoembryonic antigen (CEA) in human melanoma cells. Virchows Arch B Cell Pathol 61:81-87
    • (1991) Virchows Arch B Cell Pathol , vol.61 , pp. 81-87
    • Om, A.1    Ghose, T.2    Rowden, G.3
  • 67
    • 0026885236 scopus 로고
    • CEA immunoreactivity in metastatic malignant melanoma
    • 1495947 1:STN:280:DyaK38zlslKrsg%3D%3D
    • Selby WL, Nance KV, Park HK (1992) CEA immunoreactivity in metastatic malignant melanoma. Mod Pathol 5:415-419
    • (1992) Mod Pathol , vol.5 , pp. 415-419
    • Selby, W.L.1    Nance, K.V.2    Park, H.K.3
  • 69
    • 0035865438 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: Clinicopathologic and prognostic significance of matrilysin expression
    • 11181677 1:CAS:528:DC%2BD3MXhvFertr0%3D
    • Yamamoto H, Itoh F, Iku S, Adachi Y, Fukushima H, Sasaki S, Mukaiya M, Hirata K, Imai K (2001) Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression. J Clin Oncol 19:1118-1127
    • (2001) J Clin Oncol , vol.19 , pp. 1118-1127
    • Yamamoto, H.1    Itoh, F.2    Iku, S.3    Adachi, Y.4    Fukushima, H.5    Sasaki, S.6    Mukaiya, M.7    Hirata, K.8    Imai, K.9
  • 70
    • 79953792348 scopus 로고    scopus 로고
    • Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration
    • 10.1002/mc.20716 21480388 1:CAS:528:DC%2BC3MXktl2is70%3D
    • Yadav V, Denning MF (2011) Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration. Mol Carcinog 50:346-352. doi: 10.1002/mc.20716
    • (2011) Mol Carcinog , vol.50 , pp. 346-352
    • Yadav, V.1    Denning, M.F.2
  • 71
    • 0141869078 scopus 로고    scopus 로고
    • The RAS signal transduction pathway and its role in radiation sensitivity
    • 10.1038/sj.onc.1206699 12947393 1:CAS:528:DC%2BD3sXmslemtLw%3D
    • McKenna WG, Muschel RJ, Gupta AK, Hahn SM, Bernhard EJ (2003) The RAS signal transduction pathway and its role in radiation sensitivity. Oncogene 22:5866-5875. doi: 10.1038/sj.onc.1206699
    • (2003) Oncogene , vol.22 , pp. 5866-5875
    • McKenna, W.G.1    Muschel, R.J.2    Gupta, A.K.3    Hahn, S.M.4    Bernhard, E.J.5
  • 73
    • 0038281227 scopus 로고    scopus 로고
    • Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002
    • 12788194 1:CAS:528:DC%2BD3sXkt1ylur4%3D
    • Gupta AK, Cerniglia GJ, Mick R, Ahmed MS, Bakanauskas VJ, Muschel RJ, McKenna WG (2003) Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002. Int J Radiat Oncol Biol Phys 56:846-853
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 846-853
    • Gupta, A.K.1    Cerniglia, G.J.2    Mick, R.3    Ahmed, M.S.4    Bakanauskas, V.J.5
  • 74
    • 75649113786 scopus 로고    scopus 로고
    • An in-vitro tumour microenvironment model using adhesion to type i collagen reveals Akt-dependent radiation resistance in renal cancer cells
    • 19828461 1:CAS:528:DC%2BC3cXhtFaksLc%3D
    • Krasny L, Shimony N, Tzukert K, Gorodetsky R, Lecht S, Nettelbeck DM, Haviv YS (2010) An in-vitro tumour microenvironment model using adhesion to type I collagen reveals Akt-dependent radiation resistance in renal cancer cells. Nephrol Dial Transplant 25:373-380
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 373-380
    • Krasny, L.1    Shimony, N.2    Tzukert, K.3    Gorodetsky, R.4    Lecht, S.5    Nettelbeck, D.M.6    Haviv, Y.S.7
  • 75
    • 27144482397 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism
    • 16253776 1:CAS:528:DC%2BD2MXhtFKhsL3O
    • Gottschalk AR, Doan A, Nakamura JL, Stokoe D, Haas-Kogan DA (2005) Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism. Int J Radiat Oncol Biol Phys 63:1221-1227
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 1221-1227
    • Gottschalk, A.R.1    Doan, A.2    Nakamura, J.L.3    Stokoe, D.4    Haas-Kogan, D.A.5
  • 76
    • 77956367056 scopus 로고    scopus 로고
    • Inhibiting PI3K/Akt pathway increases DNA damage of cervical carcinoma HeLa cells by drug radiosensitization
    • 20556582 1:CAS:528:DC%2BC3cXns1Siu70%3D
    • Xia S, Yu S, Fu Q, Liu F, Zheng W, Fu X, Zhao Y (2010) Inhibiting PI3K/Akt pathway increases DNA damage of cervical carcinoma HeLa cells by drug radiosensitization. J Huazhong Univ Sci Technolog Med Sci 30:360-364
    • (2010) J Huazhong Univ Sci Technolog Med Sci , vol.30 , pp. 360-364
    • Xia, S.1    Yu, S.2    Fu, Q.3    Liu, F.4    Zheng, W.5    Fu, X.6    Zhao, Y.7
  • 78
    • 51049105757 scopus 로고    scopus 로고
    • Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair
    • Toulany M, Kehlbach R, Florczak U, Sak A, Wang S, Chen J, Lobrich M, Rodemann HP (2008) Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair. Mol Cancer Ther 7:1771-1781
    • (2008) Mol Cancer Ther , vol.7 , pp. 1771-1781
    • Toulany, M.1    Kehlbach, R.2    Florczak, U.3    Sak, A.4
  • 79
    • 44149095198 scopus 로고    scopus 로고
    • Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival
    • 18454317 1:CAS:528:DC%2BD1cXlvFais70%3D
    • Johnson GE, Ivanov VN, Hei TK (2008) Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival. Apoptosis 13:790-802
    • (2008) Apoptosis , vol.13 , pp. 790-802
    • Johnson, G.E.1    Ivanov, V.N.2    Hei, T.K.3
  • 80
    • 0028196623 scopus 로고
    • In vitro studies of Taxol as a radiation sensitizer in human tumor cells
    • 7907149 1:CAS:528:DyaK2cXlsFagsLw%3D
    • Liebmann J, Cook JA, Fisher J, Teague D, Mitchell JB (1994) In vitro studies of Taxol as a radiation sensitizer in human tumor cells. J Natl Cancer Inst 86:441-446
    • (1994) J Natl Cancer Inst , vol.86 , pp. 441-446
    • Liebmann, J.1    Cook, J.A.2    Fisher, J.3    Teague, D.4    Mitchell, J.B.5
  • 81
    • 33846031596 scopus 로고    scopus 로고
    • CKAP4/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients
    • 17030514 1:CAS:528:DC%2BD28Xht1Kit77L
    • Conrads TP, Tocci GM, Hood BL, Zhang CO, Guo L, Koch KR, Michejda CJ, Veenstra TD, Keay SK (2006) CKAP4/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients. J Biol Chem 281:37836-37843
    • (2006) J Biol Chem , vol.281 , pp. 37836-37843
    • Conrads, T.P.1    Tocci, G.M.2    Hood, B.L.3    Zhang, C.O.4    Guo, L.5    Koch, K.R.6    Michejda, C.J.7    Veenstra, T.D.8    Keay, S.K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.