A STAT3 dimer formed by inter-chain disulphide bridging during oxidative stress

Biochemical and Biophysical Research Communications

Volumn 322, Issue 3, 2004, Pages 1005-1011

  Li, Li ^a   Shaw, Peter E ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Mass spectrometry; Redox; Signal transduction; Transcription factor

Indexed keywords

CYSTEINE; DIMER; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; DIMERIZATION; DISULFIDE BOND; HUMAN; HUMAN CELL; MASS SPECTROMETRY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ACUTE-PHASE PROTEINS; B-LYMPHOCYTES; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CYSTEINE; DIMERIZATION; DISULFIDES; DNA-BINDING PROTEINS; HUMANS; KIDNEY; OXIDATIVE STRESS; PLASMIDS; RECOMBINANT PROTEINS; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION;

EID: 4444375662     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.014     Document Type: Article

References (28)

1. H.M. Seidel, P. Lamb, and J. Rosen Pharmaceutical intervention in the JAK/STAT signalling pathway Oncogene 19 2000 2645 2656
2. T. Bowman, R. Garcia, J. Turkson, and R. Jove STATs in oncogenesis Oncogene 19 2000 2474 2488
3. T. Matsuda, T. Nakamura, K. Nakao, T. Arai, M. Katsuki, T. Heike, and T. Yokota STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells EMBO J. 18 1999 4261 4269
4. S. Ihara, K. Nakajima, T. Fukada, M. Hibi, S. Nagata, T. Hirano, and Y. Fukui Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6 EMBO J. 16 1997 5345 5352
5. E.P. Reddy, A. Korapati, P. Chaturvedi, and S. Rane IL-3 signalling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled Oncogene 19 2000 2532 2547
6. S.V. Kotenko, and S. Pestka Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes Oncogene 19 2000 2557 2565
7. T. Meyer, A. Begitt, I. Lodige, M. van Rossum, and U. Vinkemeyer Constitutive and IFN-γ-induced nuclear import of STAT1 proceed through independent pathways EMBO J. 21 2002 344 354
8. T. Meyer, A. Marg, P. Lemke, B. Wiesner, and U. Vinkemeier DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1 Genes Dev. 17 2003 1992 2005
9. L.F. Stancato, M. David, C. Carter-Su, A.C. Larner, and W.B. Pratt Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation J. Biol. Chem. 271 1996 4134 4137
10. M. Lackmann, A.G. Harpur, A.C. Oates, R.J. Mann, A. Gabriel, W. Meutermans, P.F. Alewood, I.M. Kerr, G.R. Stark, and A.F. Wilks Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes Growth Factors 16 1998 39 51
11. U. Novak, H. Ji, V. Kanagasundaram, R. Simpson, and L. Paradiso STAT3 forms stable homodimers in the presence of divalent cations prior to activation Biochem. Biophys. Res. Commun. 247 1998 558 563
12. M.I. Ndubuisi, G.G. Guo, V.A. Fried, J.D. Etlinger, and P.B. Sehgal Cellular physiology of STAT3: where's the cytoplasmic monomer? J. Biol. Chem. 274 1999 25499 25509
13. S. Haan, M. Kortylewski, I. Behrmann, W. M̈ller-Esterl, P.C. Heinrich, and F. Schaper Cytoplasmic STAT proteins associate prior to activation Biochem. J. 345 2000 417 421
14. J. Braunstein, S. Brutsaert, R. Olson, and C. Schindler STATs dimerize in the absence of phosphorylation J. Biol. Chem. 278 2003 34133 34140
15. A.K. Kretzschmar, M.C. Dinger, C. Henze, K. Brocke-Heidrich, and F. Horn Analysis of STAT3 (signal transducer and activator of transcription 3) dimerization by fluorescence resonance energy transfer in living cells Biochem. J. 377 2004 289 297
16. M. Schroder, K.M. Kroeger, H. Volk, K.A. Eidne, and G. Grutz Preassociaton of nonactivated STAT3 molecules demonstrated in living cells using bioluminescence resonance energy transfer: a new model of STAT activation? J. Leukoc. Biol. 75 2004 792 797
17. L. Li, and P.E. Shaw Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines J. Biol. Chem. 277 2002 17397 17405
18. J.A. Frost, H. Steen, P. Shapiro, T. Lewis, N. Ahn, P.E. Shaw, and M.H. Cobb Cross-cascade activation of ERKs and ternary complex factors by rho family proteins EMBO J. 16 1997 6426 6438
19. C.M. Horvath, Z. Wen, and J.E.J. Darnell A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain Genes Dev. 9 1995 984 994
20. U. Vinkemeier, S.L. Cohen, I. Moarefi, B.T. Chait, J. Kuriyan, and J.E.J. Darnell DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites EMBO J. 15 1996 5616 5626
21. S. Becker, B. Groner, and C.W. Muller Three-dimensional structure of the Stat3beta homodimer bound to DNA Nature 394 1998 145 151
22. A.H. Bild, J. Turkson, and R. Jove Cytoplasmic transport of Stat3 by receptor-mediated endocytosis EMBO J. 21 2002 3255 3263
23. A. Marg, Y. Shan, T. Meyer, T. Meissner, M. Brandenburg, and U. Vinkemeier Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1 J. Cell Biol. 165 2004 823 833
24. P.B. Sehgal Plasma membrane rafts and chaperones in cytokine/STAT signaling Acta Biochim. Pol. 50 2003 583 594
25. G.G. Guo, K. Patel, V. Kumar, M. Shah, V.A. Fried, J.D. Etlinger, and P.B. Sehgal Association of the chaperone glucose-regulated protein 58 (GRP58/ER-60/ERp57) with Stat3 in cytosol and plasma membrane complexes J. Interferon Cytokine Res. 22 2002 555 563
26. M. Carballo, M. Conde, R.E. Bekay, J. Martin-Nieto, M.J. Camacho, J. Monteseirin, J. Conde, F.J. Bedoya, and F. Sobrino Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes J. Biol. Chem. 274 1999 17580 17586
27. T. Liu, S. Castro, A.R. Brasier, M. Jamaluddin, R.P. Garofalo, and A. Casola Reactive oxygen species mediate virus-induced STAT activation J. Biol. Chem. 279 2004 2461 2469
28. A.R. Simon, U. Rai, B.L. Fanburg, and B.H. Cochran Activation of the JAK-STAT pathway by reactive oxygen species Am. J. Physiol. 44 1998 C1640 C1652