-
1
-
-
19644367000
-
Activation and signaling of the p38 MAP kinase path-way
-
Zarubin T, Han J: Activation and signaling of the p38 MAP kinase path-way Cell Res, 2005; 15: 11-18
-
(2005)
Cell Res
, vol.15
, pp. 11-18
-
-
Zarubin, T.1
Han, J.2
-
2
-
-
67749117934
-
Signal integration by JNK and p38 MAPK path-ways in cancer development
-
Wagner EF, Nebreda AR: Signal integration by JNK and p38 MAPK path-ways in cancer development. Nat Rev Cancer, 2009; 9: 537-49
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 537-549
-
-
Wagner, E.F.1
Nebreda, A.R.2
-
3
-
-
45549110307
-
Multiple pathways are involved in drug resis-tance to doxorubicin in an osteosarcoma cell line
-
Rajkumar T, Yamuna M: Multiple pathways are involved in drug resis-tance to doxorubicin in an osteosarcoma cell line. Anticancer Drugs, 2008; 19: 257-65
-
(2008)
Anticancer Drugs
, vol.19
, pp. 257-265
-
-
Rajkumar, T.1
Yamuna, M.2
-
4
-
-
78649942781
-
Drug resistance in breast cancer cells: Biophysical characterization of and doxorubicin interactions with membrane lipids
-
Peetla C, Bhave R, Vijayaraghavalu S et al: Drug resistance in breast cancer cells: biophysical characterization of and doxorubicin interactions with membrane lipids. Mol Pharm, 2010; 7: 2334-48
-
(2010)
Mol Pharm
, vol.7
, pp. 2334-2348
-
-
Peetla, C.1
Bhave, R.2
Vijayaraghavalu, S.3
-
5
-
-
74149088406
-
Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms
-
Hemauer SJ, Nanovskaya TN, Abdel-Rahman SZ et al: Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms. Biochem Pharmacol, 2010; 79: 921-25
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 921-925
-
-
Hemauer, S.J.1
Nanovskaya, T.N.2
Abdel-Rahman, S.Z.3
-
6
-
-
33749048762
-
Expression of multidrug resistance type 1gene (MDR1) P-glycoprotein in intractable epilepsy with different aetiologies: A double-labelling and electron microscopy study
-
Chengyun D, Guoming L, Elia M et al: Expression of multidrug resistance type 1gene (MDR1) P-glycoprotein in intractable epilepsy with different aetiologies: a double-labelling and electron microscopy study. Neurol Sci, 2006; 27: 245-51
-
(2006)
Neurol Sci
, vol.27
, pp. 245-251
-
-
Chengyun, D.1
Guoming, L.2
Elia, M.3
-
7
-
-
33644503533
-
Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
-
Kubota H, Ishihara H, Langmann T et al: Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis. Epilepsy Res, 2006; 68: 213-28
-
(2006)
Epilepsy Res
, vol.68
, pp. 213-228
-
-
Kubota, H.1
Ishihara, H.2
Langmann, T.3
-
8
-
-
77958099641
-
Multiple drug resistance mechanisms in cancer
-
Baguley BC: Multiple drug resistance mechanisms in cancer. Mol Biotechnol, 2010; 46: 308-16
-
(2010)
Mol Biotechnol
, vol.46
, pp. 308-316
-
-
Baguley, B.C.1
-
9
-
-
77958016107
-
Imaging of P-glycoprotein function and expression to elucidate mechanisms of pharmacoresistance in epilepsy
-
Loscher W, Langer O: Imaging of P-glycoprotein function and expression to elucidate mechanisms of pharmacoresistance in epilepsy. Curr Top Med Chem, 2010; 10: 1785-91
-
(2010)
Curr Top Med Chem
, vol.10
, pp. 1785-1791
-
-
Loscher, W.1
Langer, O.2
-
10
-
-
34848910711
-
ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy
-
Lazarowski A, Czornyj L, Lubienieki F et al: ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy. Epilepsia, 2007; 48(Suppl.5): 140-49
-
(2007)
Epilepsia
, vol.48
, Issue.SUPPL. 5
, pp. 140-149
-
-
Lazarowski, A.1
Czornyj, L.2
Lubienieki, F.3
-
11
-
-
33746925983
-
Up-regulation of P-glycoprotein expression by glutathione depletion-induced oxidative stress in rat brain microvessel endothelial cells
-
Hong H, Lu Y, Ji ZN, Liu GQ: Up-regulation of P-glycoprotein expression by glutathione depletion-induced oxidative stress in rat brain microvessel endothelial cells. J Neurochem, 2006; 98: 1465-73
-
(2006)
J Neurochem
, vol.98
, pp. 1465-1473
-
-
Hong, H.1
Lu, Y.2
Ji, Z.N.3
Liu, G.Q.4
-
12
-
-
0034185251
-
Regulation of the multidrug resistance genes by stress signals
-
Sukhai M, Piquette-Miller M: Regulation of the multidrug resistance genes by stress signals. J Pharm Pharm Sci, 2000; 3: 268-80
-
(2000)
J Pharm Pharm Sci
, vol.3
, pp. 268-280
-
-
Sukhai, M.1
Piquette-Miller, M.2
-
13
-
-
33745512111
-
Regulation of multidrug resistance by proinflammatory cytokines
-
Ho EA, Piquette-Miller M: Regulation of multidrug resistance by proinflammatory cytokines. Curr Cancer Drug Targets, 2006; 6: 295-311
-
(2006)
Curr Cancer Drug Targets
, vol.6
, pp. 295-311
-
-
Ho, E.A.1
Piquette-Miller, M.2
-
14
-
-
68649090472
-
P38(MAPK): Stress responses from molecular mechanisms to therapeutics
-
Coulthard LR, White DE, Jones DL et al: p38(MAPK): stress responses from molecular mechanisms to therapeutics. Trends Mol Med, 2009; 15: 369-79
-
(2009)
Trends Mol Med
, vol.15
, pp. 369-379
-
-
Coulthard, L.R.1
White, D.E.2
Jones, D.L.3
-
15
-
-
67749133572
-
The combination of berberine and irradiation enhances anti-cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells
-
Hur JM, Hyun MS, Lim SY et al: The combination of berberine and irradiation enhances anti-cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells. J Cell Biochem,2009; 107: 955-64
-
(2009)
J Cell Biochem
, vol.107
, pp. 955-964
-
-
Hur, J.M.1
Hyun, M.S.2
Lim, S.Y.3
-
16
-
-
23344435003
-
Activation of p38 mitogen-activated protein kinase is necessary for gemcitabine-induced cytotoxicity in human pancreatic cancer cells
-
Koizumi K, Tanno S, Nakano Y et al: Activation of p38 mitogen-activated protein kinase is necessary for gemcitabine-induced cytotoxicity in human pancreatic cancer cells. Anticancer Res, 2005; 25: 3347-53
-
(2005)
Anticancer Res
, vol.25
, pp. 3347-3353
-
-
Koizumi, K.1
Tanno, S.2
Nakano, Y.3
-
17
-
-
57149098598
-
Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, Or Src Kinase Overexpression
-
Mahon FX, Hayette S, Lagarde V et al: Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression.Cancer Res, 2008; 68: 9809-16
-
(2008)
Cancer Res
, vol.68
, pp. 9809-9816
-
-
Mahon, F.X.1
Hayette, S.2
Lagarde, V.3
-
18
-
-
0035900333
-
P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
-
Potschka H, Fedrowitz M, Loscher W: P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport, 2001; 12: 3557-60
-
(2001)
Neuroreport
, vol.12
, pp. 3557-3560
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
19
-
-
77950672853
-
The structure and functions of P-glycoprotein
-
Li Y, Yuan H, Yang K et al: The structure and functions of P-glycoprotein. Curr Med Chem, 2010; 17: 786-800
-
(2010)
Curr Med Chem
, vol.17
, pp. 786-800
-
-
Li, Y.1
Yuan, H.2
Yang, K.3
-
20
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
Borst P, Evers R, Kool M, Wijnholds J: A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst, 2000; 92: 1295-1302
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
21
-
-
0009350704
-
Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: An in vitro study
-
Kuranaga N, Shinomiya N, Mochizuki H: Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro study. BMC Cancer, 2001; 1: 10
-
(2001)
BMC Cancer
, vol.1
, pp. 10
-
-
Kuranaga, N.1
Shinomiya, N.2
Mochizuki, H.3
-
22
-
-
33748928434
-
P38 MAP kinase mediates stress-induced internalization of EGFR: Implications for cancer chemotherapy
-
Zwang Y, Yarden Y: p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy. Embo J, 2006; 25: 4195-206
-
(2006)
Embo J
, vol.25
, pp. 4195-4206
-
-
Zwang, Y.1
Yarden, Y.2
-
23
-
-
77957803841
-
The ethyl acetate extract of PGP (Phellinus inteus grown on Panax ginseng) suppresses B16F10 melanoma cell proliferation through inducing cellular differentiation and apoptosis
-
Park HJ, Han ES, Park DK: The ethyl acetate extract of PGP (Phellinus inteus grown on Panax ginseng) suppresses B16F10 melanoma cell proliferation through inducing cellular differentiation and apoptosis. J Ethnopharmacol, 2010; 132: 115-21
-
(2010)
J Ethnopharmacol
, vol.132
, pp. 115-121
-
-
Park, H.J.1
Han, E.S.2
Park, D.K.3
-
24
-
-
33646390930
-
P38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2
-
Bu SZ, Huang Q, Jiang YM et al: p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2. Apoptosis, 2006; 11: 413-25
-
(2006)
Apoptosis
, vol.11
, pp. 413-425
-
-
Bu, S.Z.1
Huang, Q.2
Jiang, Y.M.3
-
25
-
-
61349152467
-
Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells
-
Guo X, Ma N, Wang J et al: Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells. BMC Cancer, 2008; 8: 375
-
(2008)
BMC Cancer
, vol.8
, pp. 375
-
-
Guo, X.1
Ma, N.2
Wang, J.3
-
26
-
-
0032552994
-
MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products
-
Duncia JV, Santella III JB, Higley CA et al: MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products. Bioorg Med Chem Lett, 1998; 8: 2839-44
-
(1998)
Bioorg Med Chem Lett
, vol.8
, pp. 2839-2844
-
-
Duncia, J.V.1
Santella III, J.B.2
Higley, C.A.3
-
27
-
-
34447321311
-
Inhibition of the mitogen activated protein kinase pathway results in the down-regulation of P-glycoprotein
-
Katayama K, Yoshioka S, Tsukahara S et al: Inhibition of the mitogen activated protein kinase pathway results in the down-regulation of P-glycoprotein. Mol Cancer Ther, 2007; 6: 2092-102
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2092-2102
-
-
Katayama, K.1
Yoshioka, S.2
Tsukahara, S.3
-
28
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ et al: Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem, 1998; 273:18623-32
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
-
29
-
-
0032569019
-
Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase
-
Nemoto S, Xiang J, Huang S, Lin A: Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. J Biol Chem, 1998; 273: 16415-20
-
(1998)
J Biol Chem
, vol.273
, pp. 16415-16420
-
-
Nemoto, S.1
Xiang, J.2
Huang, S.3
Lin, A.4
-
30
-
-
57349151455
-
Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38
-
Sauvant C, Nowak M, Wirth C et al: Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38. Int J Cancer, 2008; 123: 2532-42
-
(2008)
Int J Cancer
, vol.123
, pp. 2532-2542
-
-
Sauvant, C.1
Nowak, M.2
Wirth, C.3
-
31
-
-
0037427122
-
NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells
-
Bentires-Alj M, Barbu V, Fillet M et al: NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 2003; 22: 90-97
-
(2003)
Oncogene
, vol.22
, pp. 90-97
-
-
Bentires-Alj, M.1
Barbu, V.2
Fillet, M.3
-
32
-
-
38449119486
-
MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65
-
Saha RN, Jana M, Pahan K: MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol, 2007; 179: 7101-9
-
(2007)
J Immunol
, vol.179
, pp. 7101-7109
-
-
Saha, R.N.1
Jana, M.2
Pahan, K.3
|