Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 2, 2012, Pages 441-450

  Hussmann, G Patrick ^a   Turner, Jill R ^b   Lomazzo, Ermelinda ^a   Venkatesh, Rashmi ^a   Cousins, Vanessa ^c   Xiao, Yingxian ^a   Yasuda, Robert P ^a   Wolfe, Barry B ^a   Perry, David C ^d   Rezvani, Amir H ^c   Levin, Edward D ^c   Blendy, Julie A ^b   Kellar, Kenneth J ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR ALPHA4BETA2; SAZETIDINE A; UNCLASSIFIED DRUG; VARENICLINE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BRAIN LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; LIGAND BINDING; LONG TERM CARE; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; RADIOLIGAND BINDING ASSAY; RAT; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; TREATMENT DURATION;

ANIMALS; AZETIDINES; BEHAVIOR, ANIMAL; BENZAZEPINES; BINDING SITES; BRAIN CHEMISTRY; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; MEMBRANES; NEURONS; NICOTINE; NICOTINIC AGONISTS; PREGNANCY; PYRIDINES; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SELF ADMINISTRATION; UP-REGULATION;

EID: 84867606345     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.198085     Document Type: Article

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