메뉴 건너뛰기




Volumn 72, Issue 20, 2012, Pages 5273-5284

Multilevel whole-genome analysis reveals candidate biomarkers in clear cell renal cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MICRORNA; MINICHROMOSOME MAINTENANCE PROTEIN 2;

EID: 84867542519     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0656     Document Type: Article
Times cited : (79)

References (49)
  • 3
    • 79958271442 scopus 로고    scopus 로고
    • Translating molecular signatures of renal cell carcinoma into clinical practice
    • White NM, Yousef GM. Translating molecular signatures of renal cell carcinoma into clinical practice. J Urol 2011;186:9-11.
    • (2011) J Urol , vol.186 , pp. 9-11
    • White, N.M.1    Yousef, G.M.2
  • 4
    • 80255138220 scopus 로고    scopus 로고
    • Targeted therapy for advanced renal cell cancer (RCC): A Cochrane systematic review of published randomised trials
    • Coppin C, Kollmannsberger C, Le L, Porzsolt F, Wilt TJ. Targeted therapy for advanced renal cell cancer (RCC): a Cochrane systematic review of published randomised trials. BJU Int 2011;108:1556-63.
    • (2011) BJU Int , vol.108 , pp. 1556-1563
    • Coppin, C.1    Kollmannsberger, C.2    Le, L.3    Porzsolt, F.4    Wilt, T.J.5
  • 5
    • 77957102468 scopus 로고    scopus 로고
    • Personalized medicine: Marking a new epoch in cancer patient management
    • Diamandis M, White NM, Yousef GM. Personalized medicine: marking a new epoch in cancer patient management. Mol Cancer Res 2010;8:1175-87.
    • (2010) Mol Cancer Res , vol.8 , pp. 1175-1187
    • Diamandis, M.1    White, N.M.2    Yousef, G.M.3
  • 6
    • 84855393367 scopus 로고    scopus 로고
    • Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets
    • Dondeti VR, Wubbenhorst B, Lal P, Gordan JD, D'Andrea K, Attiyeh EF, et al. Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets. Cancer Res 2012;72:12-21.
    • (2012) Cancer Res , vol.72 , pp. 12-21
    • Dondeti, V.R.1    Wubbenhorst, B.2    Lal, P.3    Gordan, J.D.4    D'Andrea, K.5    Attiyeh, E.F.6
  • 7
    • 39749116278 scopus 로고    scopus 로고
    • Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile
    • Cifola I, Spinelli R, Beltrame L, Peano C, Fasoli E, Ferrero S, et al. Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile. Mol Cancer 2008;7:6.
    • (2008) Mol Cancer , vol.7 , pp. 6
    • Cifola, I.1    Spinelli, R.2    Beltrame, L.3    Peano, C.4    Fasoli, E.5    Ferrero, S.6
  • 9
    • 66349100709 scopus 로고    scopus 로고
    • Patterns of gene expression and copy-number alterations in von-Hippel Lindau disease-associated and sporadic clear cell carcinoma of the kidney
    • Beroukhim R, Brunet JP, Di NA, Mertz KD, Seeley A, Pires MM, et al. Patterns of gene expression and copy-number alterations in von-Hippel Lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res 2009;69:4674-81.
    • (2009) Cancer Res , vol.69 , pp. 4674-4681
    • Beroukhim, R.1    Brunet, J.P.2    Di, N.A.3    Mertz, K.D.4    Seeley, A.5    Pires, M.M.6
  • 10
    • 70349880529 scopus 로고    scopus 로고
    • Genome-wide profiling of chromosomal alterations in renal cell carcinoma using high-density single nucleotide polymorphism arrays
    • Chen M, Ye Y, Yang H, Tamboli P, Matin S, Tannir NM, et al. Genome-wide profiling of chromosomal alterations in renal cell carcinoma using high-density single nucleotide polymorphism arrays. Int J Cancer 2009;125:2342-8.
    • (2009) Int J Cancer , vol.125 , pp. 2342-2348
    • Chen, M.1    Ye, Y.2    Yang, H.3    Tamboli, P.4    Matin, S.5    Tannir, N.M.6
  • 12
    • 45849149191 scopus 로고    scopus 로고
    • Loss of heterozygosity and copy number abnormality in clear cell renal cell carcinoma discovered by high-density Affymetrix 10K single nucleotide polymorphism mapping array
    • DOI 10.1593/neo.08160
    • Toma MI, Grosser M, Herr A, Aust DE, Meye A, Hoefling C, et al. Loss of heterozygosity and copy number abnormality in clear cell renal cell carcinoma discovered by high-density Affymetrix 10K single nucleotide polymorphism mapping array. Neoplasia 2008;10:634-42. (Pubitemid 351883879)
    • (2008) Neoplasia , vol.10 , Issue.7 , pp. 634-642
    • Toma, M.I.1    Grosser, M.2    Herr, A.3    Aust, D.E.4    Meye, A.5    Hoefling, C.6    Fuessel, S.7    Wuttig, D.8    Wirth, M.P.9    Baretton, G.B.10
  • 13
    • 59949102663 scopus 로고    scopus 로고
    • Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma
    • Klatte T, Rao PN, de MM, LaRochelle J, Shuch B, Zomorodian N, et al. Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma. J Clin Oncol 2009;27:746-53.
    • (2009) J Clin Oncol , vol.27 , pp. 746-753
    • Klatte, T.1    Rao, P.N.2    De, M.M.3    LaRochelle, J.4    Shuch, B.5    Zomorodian, N.6
  • 14
    • 78349258143 scopus 로고    scopus 로고
    • Chromosome 9p deletions identify an aggressive phenotype of clear cell renal cell carcinoma
    • La RJ, Klatte T, Dastane A, Rao N, Seligson D, Said J, et al. Chromosome 9p deletions identify an aggressive phenotype of clear cell renal cell carcinoma. Cancer 2010;116:4696-702.
    • (2010) Cancer , vol.116 , pp. 4696-4702
    • La, R.J.1    Klatte, T.2    Dastane, A.3    Rao, N.4    Seligson, D.5    Said, J.6
  • 15
    • 80455174760 scopus 로고    scopus 로고
    • Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis
    • Monzon FA, Alvarez K, Peterson L, Truong L, Amato RJ, Hernandez-McClain J, et al. Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis. Mod Pathol 2011;24:1470-9.
    • (2011) Mod Pathol , vol.24 , pp. 1470-1479
    • Monzon, F.A.1    Alvarez, K.2    Peterson, L.3    Truong, L.4    Amato, R.J.5    Hernandez-McClain, J.6
  • 16
    • 80053937503 scopus 로고    scopus 로고
    • Identification of genomic alterations associated with metastasis and cancer specific survival in clear cell renal cell carcinoma
    • Sanjmyatav J, Junker K, Matthes S, Muehr M, Sava D, Sternal M, et al. Identification of genomic alterations associated with metastasis and cancer specific survival in clear cell renal cell carcinoma. J Urol 2011;186:2078-83.
    • (2011) J Urol , vol.186 , pp. 2078-2083
    • Sanjmyatav, J.1    Junker, K.2    Matthes, S.3    Muehr, M.4    Sava, D.5    Sternal, M.6
  • 17
    • 83955161686 scopus 로고    scopus 로고
    • Meta-analysis of clear cell renal cell carcinoma gene expression defines a variant subgroup and identifies gender influences on tumor biology
    • Brannon AR, Haake SM, Hacker KE, Pruthi RS, Wallen EM, Nielsen ME, et al. Meta-analysis of clear cell renal cell carcinoma gene expression defines a variant subgroup and identifies gender influences on tumor biology. Eur Urol 2012;61:258-68.
    • (2012) Eur Urol , vol.61 , pp. 258-268
    • Brannon, A.R.1    Haake, S.M.2    Hacker, K.E.3    Pruthi, R.S.4    Wallen, E.M.5    Nielsen, M.E.6
  • 18
    • 56849096837 scopus 로고    scopus 로고
    • HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
    • Gordan JD, Lal P, Dondeti VR, Letrero R, Parekh KN, Oquendo CE, et al. HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. Cancer Cell 2008;14:435-46.
    • (2008) Cancer Cell , vol.14 , pp. 435-446
    • Gordan, J.D.1    Lal, P.2    Dondeti, V.R.3    Letrero, R.4    Parekh, K.N.5    Oquendo, C.E.6
  • 19
    • 80051551689 scopus 로고    scopus 로고
    • miRNA profiling for clear cell renal cell carcinoma: Biomarker discovery and identification of potential controls and consequences of miRNA dysregulation
    • White NM, Bao TT, Grigull J, Youssef YM, Girgis A, Diamandis M, et al. miRNA profiling for clear cell renal cell carcinoma: biomarker discovery and identification of potential controls and consequences of miRNA dysregulation. J Urol 2011;186:1077-83.
    • (2011) J Urol , vol.186 , pp. 1077-1083
    • White, N.M.1    Bao, T.T.2    Grigull, J.3    Youssef, Y.M.4    Girgis, A.5    Diamandis, M.6
  • 20
    • 64949201827 scopus 로고    scopus 로고
    • From bench to bedside: Current and future applications of molecular profiling in renal cell carcinoma
    • Arsanious A, Bjarnason GA, Yousef GM. From bench to bedside: current and future applications of molecular profiling in renal cell carcinoma. Mol Cancer 2009;8:20.
    • (2009) Mol Cancer , vol.8 , pp. 20
    • Arsanious, A.1    Bjarnason, G.A.2    Yousef, G.M.3
  • 21
    • 68549106345 scopus 로고    scopus 로고
    • Differential protein expressions in renal cell carcinoma: New biomarker discovery by mass spectrometry
    • Siu KW, DeSouza LV, Scorilas A, Romaschin AD, Honey RJ, Stewart R, et al. Differential protein expressions in renal cell carcinoma: new biomarker discovery by mass spectrometry. J Proteome Res 2009;8:3797-807.
    • (2009) J Proteome Res , vol.8 , pp. 3797-3807
    • Siu, K.W.1    DeSouza, L.V.2    Scorilas, A.3    Romaschin, A.D.4    Honey, R.J.5    Stewart, R.6
  • 23
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based DNA copy number data
    • DOI 10.1093/biostatistics/kxh008
    • Olshen AB, Venkatraman ES, Lucito R, Wigler M. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 2004;5:557-72. (Pubitemid 41180205)
    • (2004) Biostatistics , vol.5 , Issue.4 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3    Wigler, M.4
  • 24
    • 38049100456 scopus 로고    scopus 로고
    • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
    • Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A 2007;104:20007-12.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20007-20012
    • Beroukhim, R.1    Getz, G.2    Nghiemphu, L.3    Barretina, J.4    Hsueh, T.5    Linhart, D.6
  • 28
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
    • Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012;2:401-4.
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1    Gao, J.2    Dogrusoz, U.3    Gross, B.E.4    Sumer, S.O.5    Aksoy, B.A.6
  • 29
    • 84863550037 scopus 로고    scopus 로고
    • Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression
    • Selamat SA, Chung BS, Girard L, Zhang W, Zhang Y, Campan M, et al. Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res 2012;22:1197-211.
    • (2012) Genome Res , vol.22 , pp. 1197-1211
    • Selamat, S.A.1    Chung, B.S.2    Girard, L.3    Zhang, W.4    Zhang, Y.5    Campan, M.6
  • 31
    • 81955164748 scopus 로고    scopus 로고
    • MiRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215
    • White NM, Khella HW, Grigull J, Adzovic S, Youssef YM, Honey RJ, et al. miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215. Br J Cancer 2011;105:1741-9.
    • (2011) Br J Cancer , vol.105 , pp. 1741-1749
    • White, N.M.1    Khella, H.W.2    Grigull, J.3    Adzovic, S.4    Youssef, Y.M.5    Honey, R.J.6
  • 32
    • 67349179639 scopus 로고    scopus 로고
    • CSF1R copy number changes, point mutations, and RNA and protein overexpression in renal cell carcinomas
    • Soares MJ, Pinto M, Henrique R, Vieira J, Cerveira N, Peixoto A, et al. CSF1R copy number changes, point mutations, and RNA and protein overexpression in renal cell carcinomas. Mod Pathol 2009;22:744-52.
    • (2009) Mod Pathol , vol.22 , pp. 744-752
    • Soares, M.J.1    Pinto, M.2    Henrique, R.3    Vieira, J.4    Cerveira, N.5    Peixoto, A.6
  • 33
    • 84857358303 scopus 로고    scopus 로고
    • Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma
    • Minner S, Rump D, Tennstedt P, Simon R, Burandt E, Terracciano L, et al. Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma. Cancer 2012;118:1268-75.
    • (2012) Cancer , vol.118 , pp. 1268-1275
    • Minner, S.1    Rump, D.2    Tennstedt, P.3    Simon, R.4    Burandt, E.5    Terracciano, L.6
  • 34
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: Normal and abnormal functions
    • DOI 10.1210/en.2004-0959
    • Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 2004;145:5439-47. (Pubitemid 39564581)
    • (2004) Endocrinology , vol.145 , Issue.12 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 35
    • 42349098965 scopus 로고    scopus 로고
    • The quest for the 1p36 tumor suppressor
    • DOI 10.1158/0008-5472.CAN-07-2095
    • Bagchi A, Mills AA. The quest for the 1p36 tumor suppressor. Cancer Res 2008;68:2551-6. (Pubitemid 351556249)
    • (2008) Cancer Research , vol.68 , Issue.8 , pp. 2551-2556
    • Bagchi, A.1    Mills, A.A.2
  • 37
    • 72149117661 scopus 로고    scopus 로고
    • Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia
    • Law AY, Wong CK. Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia. Exp Cell Res 2010;316:466-76.
    • (2010) Exp Cell Res , vol.316 , pp. 466-476
    • Law, A.Y.1    Wong, C.K.2
  • 39
    • 77952878558 scopus 로고    scopus 로고
    • Carbonic anhydrase IX in renal cell carcinoma: Implications for prognosis, diagnosis, and therapy
    • Stillebroer AB, Mulders PF, Boerman OC, Oyen WJ, Oosterwijk E. Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy. Eur Urol 2010;58:75-83.
    • (2010) Eur Urol , vol.58 , pp. 75-83
    • Stillebroer, A.B.1    Mulders, P.F.2    Boerman, O.C.3    Oyen, W.J.4    Oosterwijk, E.5
  • 40
    • 79251558134 scopus 로고    scopus 로고
    • Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells
    • Tang SW, Yang TC, Lin WC, Chang WH, Wang CC, Lai MK, et al. Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells. Carcinogenesis 2011;32:138-45.
    • (2011) Carcinogenesis , vol.32 , pp. 138-145
    • Tang, S.W.1    Yang, T.C.2    Lin, W.C.3    Chang, W.H.4    Wang, C.C.5    Lai, M.K.6
  • 41
    • 3442894720 scopus 로고    scopus 로고
    • Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer
    • DOI 10.1158/0008-5472.CAN-04-0799
    • Hoque MO, Begum S, Topaloglu O, Jeronimo C, Mambo E, Westra WH, et al. Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. Cancer Res 2004;64:5511-7. (Pubitemid 39006576)
    • (2004) Cancer Research , vol.64 , Issue.15 , pp. 5511-5517
    • Hoque, M.O.1    Begum, S.2    Topaloglu, O.3    Jeronimo, C.4    Mambo, E.5    Westra, W.H.6    Califano, J.A.7    Sidransky, D.8
  • 42
    • 77950859659 scopus 로고    scopus 로고
    • Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma
    • Morris MR, Ricketts C, Gentle D, Abdulrahman M, Clarke N, Brown M, et al. Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma. Oncogene 2010;29:2104-17.
    • (2010) Oncogene , vol.29 , pp. 2104-2117
    • Morris, M.R.1    Ricketts, C.2    Gentle, D.3    Abdulrahman, M.4    Clarke, N.5    Brown, M.6
  • 43
    • 25144453762 scopus 로고    scopus 로고
    • Messenger RNA expression ratios among four genes predict subtypes of renal cell carcinoma and distinguish oncocytoma from carcinoma
    • DOI 10.1158/1078-0432.CCR-05-0647
    • Chen YT, Tu JJ, Kao J, Zhou XK, Mazumdar M. Messenger RNA expression ratios among four genes predict subtypes of renal cell carcinoma and distinguish oncocytoma from carcinoma. Clin Cancer Res 2005;11:6558-66. (Pubitemid 41338995)
    • (2005) Clinical Cancer Research , vol.11 , Issue.18 , pp. 6558-6566
    • Chen, Y.-T.1    Tu, J.J.2    Kao, J.3    Zhou, X.K.4    Mazumdar, M.5
  • 44
    • 76649130555 scopus 로고    scopus 로고
    • Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship
    • Kim H, Huang W, Jiang X, Pennicooke B, Park PJ, Johnson MD. Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship. Proc Natl Acad Sci U S A 2010;107:2183-8.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2183-2188
    • Kim, H.1    Huang, W.2    Jiang, X.3    Pennicooke, B.4    Park, P.J.5    Johnson, M.D.6
  • 45
    • 58149239686 scopus 로고    scopus 로고
    • Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
    • Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 2008;322:1695-9.
    • (2008) Science , vol.322 , pp. 1695-1699
    • Varambally, S.1    Cao, Q.2    Mani, R.S.3    Shankar, S.4    Wang, X.5    Ateeq, B.6
  • 47
    • 79953306841 scopus 로고    scopus 로고
    • DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy
    • Moeller BJ, Yordy JS, Williams MD, Giri U, Raju U, Molkentine DP, et al. DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy. Clin Cancer Res 2011;17:2035-43.
    • (2011) Clin Cancer Res , vol.17 , pp. 2035-2043
    • Moeller, B.J.1    Yordy, J.S.2    Williams, M.D.3    Giri, U.4    Raju, U.5    Molkentine, D.P.6
  • 48
    • 79958289707 scopus 로고    scopus 로고
    • A specific gene expression signature characterizes metastatic potential in clear cell renal cell carcinoma
    • Sanjmyatav J, Steiner T, Wunderlich H, Diegmann J, Gajda M, Junker K. A specific gene expression signature characterizes metastatic potential in clear cell renal cell carcinoma. J Urol 2011;186:289-94.
    • (2011) J Urol , vol.186 , pp. 289-294
    • Sanjmyatav, J.1    Steiner, T.2    Wunderlich, H.3    Diegmann, J.4    Gajda, M.5    Junker, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.