Identification of Stanniocalcin 2 as Prognostic Marker in Renal Cell Carcinoma

European Urology

Volumn 55, Issue 3, 2009, Pages 669-678

  Meyer, Hellmuth A ^a   Tölle, Angelika ^a   Jung, Monika ^a   Fritzsche, Florian R ^a   Haendler, Bernard ^b   Kristiansen, Ilka ^c   Gaspert, Ariana ^c   Johannsen, Manfred ^a   Jung, Klaus ^d   Kristiansen, Glen ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BAYER PHARMA AG   (Germany)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d Berlin Institute for Urologic Research   (Germany)

Author keywords

Prognostic factor; RCC; STC2; TMA

Indexed keywords

GLYCOPROTEIN; STANNIOCALCIN 2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CALCIUM TRANSPORT; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GLOMERULUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; KIDNEY DISTAL TUBULE; MAJOR CLINICAL STUDY; MALE; NEPHRECTOMY; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CARCINOMA, RENAL CELL; FEMALE; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; SURVIVAL RATE;

EID: 58849098751     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2008.04.001     Document Type: Article

References (29)

1. Jemal A., Siegel R., Ward E., Murray T., Xu J., and Thun M.J. Cancer statistics, 2007. CA Cancer J Clin 57 (2007) 43-66
2. Van Poppel H., Da Pozzo L., Albrecht W., et al. A prospective randomized EORTC intergroup phase 3 study comparing the complications of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol 51 (2007) 1606-1615
3. De Mulder P.H.M., Patard J.-J., Szczylik C., Otto T., and Eisen T. Current status of targeted therapy in metastatic renal cell carcinoma. Eur Urol Suppl 6 (2007) 665-671
4. Ficarra V., Galfano A., Verhoest G., et al. Prognostic factors and staging systems for renal cell carcinoma. Eur Urol Suppl 6 (2007) 623-629
5. Schips L., Dalpiaz O., Lipsky K., et al. Serum levels of vascular endothelial growth factor (VEGF) and endostatin in renal cell carcinoma patients compared to a control group. Eur Urol 51 (2007) 168-174
6. Ohl F., Jung M., Radonic A., Sachs M., Loening S.A., and Jung K. Identification and validation of suitable endogenous reference genes for gene expression studies of human bladder cancer. J Urol 175 (2006) 1915-1920
7. Jung M., Ramankulov A., Roigas J., et al. In search of suitable reference genes for gene expression studies of human renal cell carcinoma by real-time PCR. BMC Mol Biol 8 (2007) 47
8. Kristiansen G., Yu Y., Petersen S., et al. Overexpression of c-erbB2 protein correlates with disease-stage and chromosomal gain at the c-erbB2 locus in non-small cell lung cancer. Eur J Cancer 37 (2001) 1089-1095
9. Jones J., Otu H., Spentzos D., et al. Gene signatures of progression and metastasis in renal cell cancer. Clin Cancer Res 11 (2005) 5730-5739
10. Lenburg M.E., Liou L.S., Gerry N.P., Frampton G.M., Cohen H.T., and Christman M.F. Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data. BMC Cancer 3 (2003) 31
11. Wagner G.F., and Jaworski E. Calcium regulates stanniocalcin mRNA levels in primary cultured rainbow trout corpuscles of stannius. Mol Cell Endocrinol 99 (1994) 315-322
12. Fenwick J.C., and So Y.P. A perfusion study of the effect of stanniectomy on the net influx of calcium 45 across an isolated eel gill (1). J Exp Zool 188 (1974) 125-131
13. Wagner G.F., Milliken C., Friesen H.G., and Copp D.H. Studies on the regulation and characterization of plasma stanniocalcin in rainbow trout. Mol Cell Endocrinol 79 (1991) 129-138
14. Lu M., Wagner G.F., and Renfro J.L. Stanniocalcin stimulates phosphate reabsorption by flounder renal proximal tubule in primary culture. Am J Physiol 267 (1994) R1356-R1362
15. Sundell K., Bjornsson B.T., Itoh H., and Kawauchi H. Chum salmon (Oncorhynchus keta) stanniocalcin inhibits in vitro intestinal calcium uptake in Atlantic cod (Gadus morhua). J Comp Physiol [B] 162 (1992) 489-495
16. Chang A.C., Janosi J., Hulsbeek M., et al. A novel human cDNA highly homologous to the fish hormone stanniocalcin. Mol Cell Endocrinol 112 (1995) 241-247
17. Olsen H.S., Cepeda M.A., Zhang Q.Q., Rosen C.A., and Vozzolo B.L. Human stanniocalcin: a possible hormonal regulator of mineral metabolism. Proc Natl Acad Sci U S A 93 (1996) 1792-1796
18. Ishibashi K., Miyamoto K., Taketani Y., et al. Molecular cloning of a second human stanniocalcin homologue (STC2). Biochem Biophys Res Commun 250 (1998) 252-258
19. Wagner G.F., Vozzolo B.L., Jaworski E., et al. Human stanniocalcin inhibits renal phosphate excretion in the rat. J Bone Miner Res 12 (1997) 165-171
20. Madsen K.L., Tavernini M.M., Yachimec C., et al. Stanniocalcin: a novel protein regulating calcium and phosphate transport across mammalian intestine. Am J Physiol 274 (1998) G96-G102
21. Varghese R., Gagliardi A.D., Bialek P.E., Yee S.P., Wagner G.F., and Dimattia G.E. Overexpression of human stanniocalcin affects growth and reproduction in transgenic mice. Endocrinology 143 (2002) 868-876
22. Chang A.C., Jellinek D.A., and Reddel R.R. Mammalian stanniocalcins and cancer. Endocr Relat Cancer 10 (2003) 359-373
23. Honda S., Kashiwagi M., Ookata K., Tojo A., and Hirose S. Regulation by 1alpha,25-dihydroxyvitamin D(3) of expression of stanniocalcin messages in the rat kidney and ovary. FEBS Lett 459 (1999) 119-122
24. McCudden C.R., James K.A., Hasilo C., and Wagner G.F. Characterization of mammalian stanniocalcin receptors. Mitochondrial targeting of ligand and receptor for regulation of cellular metabolism. J Biol Chem 277 (2002) 45249-45258
25. Ljungberg B., Hanbury D.C., Kuczyk M.A., et al. Renal cell carcinoma guideline. Eur Urol 51 (2007) 1502-1510
26. Bouras T., Southey M.C., Chang A.C., et al. Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer. Cancer Res 62 (2002) 1289-1295
27. Langner C., Ratschek M., Rehak P., Schips L., and Zigeuner R. Steroid hormone receptor expression in renal cell carcinoma: an immunohistochemical analysis of 182 tumors. J Urol 171 (2004) 611-614
28. Esseghir S., Kennedy A., Seedhar P., et al. Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. Clin Cancer Res 13 (2007) 3164-3173
29. Ito D., Walker J.R., Thompson C.S., et al. Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties. Mol Cell Biol 24 (2004) 9456-9469