Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells

Carcinogenesis

Volumn 32, Issue 2, 2011, Pages 138-145

  Tang, Sai Wen ^a   Yang, Tsung Cheng ^a   Lin, Wei Chou ^a,b   Chang, Wen Hsin ^a   Wang, Chung Chieh ^a,b   Lai, Ming Kuen ^a,b   Lin, Jung Yaw ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRIX METALLOPROTEINASE INHIBITOR; NICOTINAMIDE METHYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ANTIBODY; PROTEIN KINASE B; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CANCER TISSUE; CARCINOMA CELL; CELL INVASION; CELL STRAIN HEK293; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

EID: 79251558134     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq225     Document Type: Article

References (47)

1. Cohen,H.T. et al. (2005) Renal-cell carcinoma. N. Engl. J. Med., 353, 2477-2490.
2. Jemal,A. et al. (2008) Cancer statistics, 2008. CA Cancer J. Clin., 58, 71-96.
3. Mancini,V. et al. (2008) Current insights in renal cell cancer pathology. Urol. Oncol., 26, 225-238.
4. Russo,P. (2000) Renal cell carcinoma: presentation, staging and surgical treatment. Semin. Oncol., 27, 160-176.
5. Ishimura,T. et al. (2004) Microscopic venous invasion in renal cell carcinoma as a predictor of recurrence after radical surgery. Int. J. Urol., 11, 264-268.
6. Amato,R.J. (2000) Chemotherapy for renal cell carcinoma. Semin. Oncol., 27, 177-186.
7. Lane,B.R. et al. (2007) Targeted molecular therapy for renal cell carcinoma. Urology, 69, 3-10.
8. Deryugina,E.I. et al. (2006) Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev., 25, 9-34.
9. Liotta,L.A. et al. (1991) Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res., 51, 5054s-5059s.
10. Mook,O.R. et al. (2004) The role of gelatinases in colorectal cancer progression and metastasis. Biochim. Biophys. Acta., 1705, 69-89.
11. Qin,H. et al. (1999) The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells. J. Biol. Chem., 274, 29130-29137.
12. Bae,I.H. et al. (2006) Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1. Cancer Res., 66, 4991-4995.
13. Cheung,L.W. et al. (2006) Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9. Cancer Res., 66, 10902-10910.
14. Hu,B. et al. (2006) Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res., 66, 775-783.
15. Park,M.J. et al. (2007) Nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinase/Akt signaling pathway and AP-2 transcription factor. J. Biol. Chem., 282, 30485-30496.
16. Song,H. et al. (2006) Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells. Cancer Res., 66, 10487-10496.
17. Aksoy,S. et al. (1994) Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization. J. Biol. Chem., 269, 14835-14840.
18. Roessler,M. et al. (2005) Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. Clin. Cancer Res., 11, 6550-6557.
19. Xu,J. et al. (2003) Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J. Clin. Endocrinol. Metab., 88, 4990-4996.
20. Rogers,C.D. et al. (2006) Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs. Cancer Biol. Ther., 5, 1383-1389.
21. Lim,B.H. et al. (2006) Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification. Exp. Mol. Med., 38, 455-465.
22. Lal,A. et al. (1999) A public database for gene expression in human cancers. Cancer Res., 59, 5403-5407.
23. Sartini,D. et al. (2007) Nicotinamide N-methyltransferase upregulation inversely correlates with lymph node metastasis in oral squamous cell carcinoma. Mol. Med., 13, 415-421.
24. Kim,J. et al. (2009) Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis. J. Exp. Clin. Cancer Res., 28, 20.
25. Wu,Y. et al. (2008) Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration. Oncogene, 27, 6679-6689.
26. Yao,M. et al. (2005) Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma. J. Pathol., 205, 377-387.
27. Zhang,J. et al. (2010) Nicotinamide N-methyltransferase protein expression in renal cell cancer. J. Zhejiang Univ. Sci. B., 11, 136-143.
28. Sartini,D. et al. (2006) Identification of nicotinamide N-methyltransferase as a novel tumor marker for renal clear cell carcinoma. J. Urol., 176, 2248-2254.
29. Tomida,M. et al. (2009) Serum levels of nicotinamide N-methyltransferase in patients with lung cancer. J. Cancer Res. Clin. Oncol., 135, 1223-1229.
30. Tang,S.W. et al. (2006) Identification of differentially expressed genes in clear cell renal cell carcinoma by analysis of full-length enriched cDNA library. J. Biomed. Sci., 13, 233-240.
31. Tang,S.W. et al. (2009) MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cells. Cancer Lett., 273, 35-43.
32. Bostwick,D.G. et al. (1999) Diagnosis and classification of renal cell carcinoma. Urol. Clin. North Am., 26, 627-635.
33. Livak,K.J. et al. (2001) Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C (T)) Method. Methods, 25, 402-408.
34. Bian,J. et al. (1997) Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter. Mol. Cell. Biol., 17, 6330-6338.
35. Schnaper,H.W. et al. (1993) Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro. J. Cell. Physiol., 156, 235-246.
36. Emonard,H. et al. (1999) Inhibition of gelatinase A by oleic acid. Ann. N. Y. Acad. Sci., 878, 647-649.
37. Egeblad,M. et al. (2002) New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer, 2, 161-174.
38. Maeta,H. et al. (2001) Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas. Virchows Arch., 438, 121-128.
39. Vasala,K. et al. (2003) Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer. Urology, 62, 952-957.
40. Rao,J.S. (2003) Molecular mechanisms of glioma invasiveness: the role of proteases. Nat. Rev. Cancer, 3, 489-501.
41. Takahashi,M. et al. (2002) Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma. Int. J. Urol., 9, 531-538.
42. Kim,E.S. et al. (2007) TGF-beta-induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells. Cancer Lett., 252, 147-156.
43. Ito,H. et al. (2004) Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2. Cancer Res., 64, 7439-7446.
44. Safe,S. et al. (2005) Sp transcription factor family and its role in cancer. Eur. J. Cancer, 41, 2438-2448.
45. Pore,N. et al. (2004) Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism. Mol. Biol. Cell, 15, 4841-4853.
46. Wang,D. et al. (2002) Activation of Ras/Erk pathway by a novel METinteracting protein RanBPM. J. Biol. Chem., 277, 36216-36222.
47. Carnero,A. et al. (2008) The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Curr. Cancer Drug Targets, 8, 187-198.