Serum metabolomics in a helicobacter hepaticus mouse model of inflammatory bowel disease reveal important changes in the microbiome, serum peptides, and intermediary metabolism

Journal of Proteome Research

Volumn 11, Issue 10, 2012, Pages 4916-4926

  Lu, Kun ^a   Knutson, Charles G ^a   Wishnok, John S ^a   Fox, James G ^a,b   Tannenbaum, Steven R ^a,b  

^a Massachusetts Institute of Technology   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Helicobacter hepaticus; inflammatory bowel disease; metabolomics; microbiome; mouse model

Indexed keywords

ALPHA 2 MACROGLOBULIN; COMPLEMENT COMPONENT C4; FIBRINOGEN; GLYCEROPHOSPHOLIPID; HOMOCYSTEINE; METHIONINE; RAG2 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; ENTERITIS; FATTY ACID METABOLISM; HELICOBACTER HEPATICUS; HELICOBACTER INFECTION; INFLAMMATION; INTESTINE FLORA; METABOLISM; METABOLOMICS; MICROBIOME; MOUSE; NONHUMAN; PEPTIDOMICS; PRIORITY JOURNAL; PURINE METABOLISM; TRYPTOPHAN METABOLISM;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PROTEINS; CLUSTER ANALYSIS; DNA-BINDING PROTEINS; ENERGY METABOLISM; FATTY ACIDS; HELICOBACTER HEPATICUS; HELICOBACTER INFECTIONS; INFLAMMATORY BOWEL DISEASES; LIPID METABOLISM; METAGENOME; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MULTIVARIATE ANALYSIS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PRINCIPAL COMPONENT ANALYSIS; TANDEM MASS SPECTROMETRY;

EID: 84867459282     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300429x     Document Type: Article

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