Mechanism of feedback allosteric inhibition of ATP phosphoribosyltransferase

Biochemistry

Volumn 51, Issue 40, 2012, Pages 8027-8038

  Pedreño, Sònia ^a   Pisco, João Pedro ^a   Larrouy Maumus, Gérald ^a   Kelly, Geoff ^b   De Carvalho, Luiz Pedro Sório ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC INHIBITION; AMINO GROUP; ANTI-INFECTIVES; FEEDBACK REGULATION; GEL FILTRATION; HEXAMERS; KINETIC EXPERIMENT; L-HISTIDINE; MYCOBACTERIUM TUBERCULOSIS; NEUTRAL IMIDAZOLE; OVERALL REACTIONS; PH DEPENDENCE; PH VALUE; PHOSPHORIBOSYLTRANSFERASE; POTENTIAL TARGETS; RATE LIMITING; STEADY-STATE KINETICS;

AMINO ACIDS; EXPERIMENTS; KINETICS;

ENZYME INHIBITION;

ADENOSINE TRIPHOSPHATE PHOSPHORIBOSYLTRANSFERASE; ALPHA AMINO ACID; HISTIDINE; IMIDAZOLE;

ALLOSTERISM; ARTICLE; ENZYME BINDING; ENZYME KINETICS; ENZYME PURIFICATION; FEEDBACK SYSTEM; MOLECULAR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ATP PHOSPHORIBOSYLTRANSFERASE; ESCHERICHIA COLI; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTIDINE; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS;

EID: 84867453536     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300808b     Document Type: Article

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