Crystal structure of HslUV complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of HslV by HslU

Journal of Molecular Biology

Volumn 318, Issue 3, 2002, Pages 779-785

  Sousa, Marcelo C ^a   Kessler, Benedikt M ^b   Overkleeft, Herman S ^b   McKay, David B ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

HslUV (Haemophilus influenzae); Protease inhibitor; Proteasome; Vinyl sulfone; X ray crystallography

Indexed keywords

PROTEIN; PROTEIN HSIUV; PROTEINASE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; HAEMOPHILUS INFLUENZAE TYPE A; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

EUKARYOTA; HAEMOPHILUS; HAEMOPHILUS INFLUENZAE;

EID: 0036308646     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00145-6     Document Type: Article

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