-
2
-
-
55749109703
-
Interferon-based therapy for chronic hepatitis C: Current and future perspectives
-
Zeuzem S. Interferon-based therapy for chronic hepatitis C: current and future perspectives. Nat Clin Pract Gastroenterol Hepatol 2008;5:610-622
-
(2008)
Nat Clin Pract Gastroenterol Hepatol
, vol.5
, pp. 610-622
-
-
Zeuzem, S.1
-
3
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009;461:399-401
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
-
5
-
-
65449171953
-
Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
-
Hezode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009;360:1839-1850
-
(2009)
N Engl J Med
, vol.360
, pp. 1839-1850
-
-
Hezode, C.1
Forestier, N.2
Dusheiko, G.3
-
6
-
-
65449152185
-
Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection
-
McHutchison JG, Everson GT, Gordon SC, et al. Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection. N Engl J Med 2009;360:1827-1838
-
(2009)
N Engl J Med
, vol.360
, pp. 1827-1838
-
-
McHutchison, J.G.1
Everson, G.T.2
Gordon, S.C.3
-
7
-
-
67650556135
-
HCV SPRINT-1 final results: SVR 24 from a phase 2 study of boceprevir plus Pegintron (peginterferon alfa-2b)/ ribavirin in treatment-naive subjects with genotype-1 chronic hepatitis C [abstract 4]
-
Kwo P, Lawitz E, McCone J, et al. HCV SPRINT-1 final results: SVR 24 from a phase 2 study of boceprevir plus Pegintron (peginterferon alfa-2b)/ ribavirin in treatment-naive subjects with genotype-1 chronic hepatitis C [abstract 4]. J Hepatol 2009;50(Suppl 1):S4
-
(2009)
J Hepatol
, vol.50
, Issue.SUPPL. 1
-
-
Kwo, P.1
Lawitz, E.2
McCone, J.3
-
8
-
-
72049110626
-
Randomized trial comparing systemic and local reactions to controlled-release interferon alpha2b and pegylated-interferon alpha2b in hepatitis C patients who failed prior treatment [abstract 628]
-
Lawitz E, Younossi ZM, Shiffman M, et al. Randomized trial comparing systemic and local reactions to controlled-release interferon alpha2b and pegylated-interferon alpha2b in hepatitis C patients who failed prior treatment [abstract 628]. J Hepatol 2009;50(Suppl 1):S231
-
(2009)
J Hepatol
, vol.50
, Issue.SUPPL. 1
-
-
Lawitz, E.1
Younossi, Z.M.2
Shiffman, M.3
-
9
-
-
35748939037
-
Phase 2 study of omega interferon alone or in combination with ribavirin in subjects with chronic hepatitis C genotype-1 infection [abstract 11]
-
Novozhenov V, Zakharova N, Vinogradova E, et al. Phase 2 study of omega interferon alone or in combination with ribavirin in subjects with chronic hepatitis C genotype-1 infection [abstract 11]. J Hepatol 2007;46(Suppl 1):S8
-
(2007)
J Hepatol
, vol.46
, Issue.SUPPL. 1
-
-
Novozhenov, V.1
Zakharova, N.2
Vinogradova, E.3
-
10
-
-
67650558336
-
Interim results from a phase Ib dose-escalation study of 4 weeks of PEG-interferon lambda (PEG-rIL-29) treatment in subjects with hepatitis C virus (HCV) genotype 1 with prior virologic response and relapse to eginterferon alfa and ribavirin [abstract 170]
-
Lawitz E, Zaman A, Muir AJ, et al. Interim results from a phase Ib dose-escalation study of 4 weeks of PEG-interferon lambda (PEG-rIL-29) treatment in subjects with hepatitis C virus (HCV) genotype 1 with prior virologic response and relapse to eginterferon alfa and ribavirin [abstract 170]. Hepatology 2008;48(Suppl 1):385A
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Lawitz, E.1
Zaman, A.2
Muir, A.J.3
-
11
-
-
34547099363
-
The interferons. 50 years after their discovery, there is much more to learn
-
Pestka S. The interferons. 50 years after their discovery, there is much more to learn. J Biol Chem 2007;282:20047-20051
-
(2007)
J Biol Chem
, vol.282
, pp. 20047-20051
-
-
Pestka, S.1
-
12
-
-
0036827834
-
Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-alpha fusion protein in cynomolgus monkeys
-
Osborn BL, Olsen HS, Nardelli B, et al. Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-alpha fusion protein in cynomolgus monkeys. J Pharmacol Exp Ther 2002;303:540-548
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 540-548
-
-
Osborn, B.L.1
Olsen, H.S.2
Nardelli, B.3
-
13
-
-
33750937197
-
Modulation of interferon-specific gene expression by albumin-interferon- alpha in interferon-alpha-experienced patients with chronic hepatitis C
-
Balan V, Nelson DR, Sulkowski MS, et al. Modulation of interferon-specific gene expression by albumin-interferon-alpha in interferon-alpha-experienced patients with chronic hepatitis C. Antivir Ther 2006;11:901-908
-
(2006)
Antivir Ther
, vol.11
, pp. 901-908
-
-
Balan, V.1
Nelson, D.R.2
Sulkowski, M.S.3
-
14
-
-
23944462641
-
Mechanism of action of interferon and ribavirin in treatment of hepatitis C
-
Feld JJ, Hoofnagle JH. Mechanism of action of interferon and ribavirin in treatment of hepatitis C. Nature 2005;436:967-972
-
(2005)
Nature
, vol.436
, pp. 967-972
-
-
Feld, J.J.1
Hoofnagle, J.H.2
-
15
-
-
33746523062
-
Dynamics of interferon-specific gene expression in peripheral blood of interferon alfa-naive patients with genotype 1 chronic hepatitis C infection treated with albumin-interferon alfa
-
Bain VG, Yoshida EM, Kaita KD, et al. Dynamics of interferon-specific gene expression in peripheral blood of interferon alfa-naive patients with genotype 1 chronic hepatitis C infection treated with albumin-interferon alfa. Hepatol Res 2006;35:256-262
-
(2006)
Hepatol Res
, vol.35
, pp. 256-262
-
-
Bain, V.G.1
Yoshida, E.M.2
Kaita, K.D.3
-
16
-
-
34548610612
-
Anti-hepatitis C virus activity of albinterferon alfa-2b in cell culture
-
Liu C, Zhu H, Subramanian GM, et al. Anti-hepatitis C virus activity of albinterferon alfa-2b in cell culture. Hepatol Res 2007;37:941-947
-
(2007)
Hepatol Res
, vol.37
, pp. 941-947
-
-
Liu, C.1
Zhu, H.2
Subramanian, G.M.3
-
17
-
-
0042990542
-
A phase 1 study to evaluate the pharmacokinetics, safety, and tolerability of escalating doses of a novel recombinant human albumin-interferonalpha fusion protein (albuferon™) in subjects with chronic hepatitis C [abstract 490]
-
Davis GL, Balan V, Sulkowski MS, et al. A phase 1 study to evaluate the pharmacokinetics, safety, and tolerability of escalating doses of a novel recombinant human albumin-interferonalpha fusion protein (albuferon™) in subjects with chronic hepatitis C [abstract 490]. Hepatology 2002;36:285A
-
(2002)
Hepatology
, vol.36
-
-
Davis, G.L.1
Balan, V.2
Sulkowski, M.S.3
-
18
-
-
33644918919
-
A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients
-
Bain VG, Kaita KD, Yoshida EM, et al. A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients. J Hepatol 2006;44:671-678
-
(2006)
J Hepatol
, vol.44
, pp. 671-678
-
-
Bain, V.G.1
Kaita, K.D.2
Yoshida, E.M.3
-
19
-
-
33644551889
-
A Phase I/II study evaluating escalating doses of recombinant human albumin-interferon-alpha fusion protein in chronic hepatitis C patients who have failed previous interferon-alpha-based therapy
-
Balan V, Nelson DR, Sulkowski MS, et al. A Phase I/II study evaluating escalating doses of recombinant human albumin-interferon-alpha fusion protein in chronic hepatitis C patients who have failed previous interferon-alpha-based therapy. Antivir Ther 2006;11:35-45
-
(2006)
Antivir Ther
, vol.11
, pp. 35-45
-
-
Balan, V.1
Nelson, D.R.2
Sulkowski, M.S.3
-
20
-
-
49649089488
-
Albinterferon alfa-2b dosed every two or four weeks in interferon-naive patients with genotype 1 chronic hepatitis C
-
Zeuzem S, Yoshida EM, Benhamou Y, et al. Albinterferon alfa-2b dosed every two or four weeks in interferon-naive patients with genotype 1 chronic hepatitis C. Hepatology 2008;48:407-417
-
(2008)
Hepatology
, vol.48
, pp. 407-417
-
-
Zeuzem, S.1
Yoshida, E.M.2
Benhamou, Y.3
-
21
-
-
44749094657
-
Safety and antiviral activity of albinterferon alfa-2b dosed every four weeks in genotype 2/3 chronic hepatitis C patients
-
Bain VG, Kaita KD, Marotta P, et al. Safety and antiviral activity of albinterferon alfa-2b dosed every four weeks in genotype 2/3 chronic hepatitis C patients. Clin Gastroenterol Hepatol 2008;6:701-706
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 701-706
-
-
Bain, V.G.1
Kaita, K.D.2
Marotta, P.3
-
23
-
-
58849122392
-
Safety and antiviral activity of albinterferon alfa-2b in prior non-responders with chronic hepatitis C
-
Nelson DR, Rustgi V, Balan V, et al. Safety and antiviral activity of albinterferon alfa-2b in prior non-responders with chronic hepatitis C. Clin Gastro Hepatol 2009;7:212-218
-
(2009)
Clin Gastro Hepatol
, vol.7
, pp. 212-218
-
-
Nelson, D.R.1
Rustgi, V.2
Balan, V.3
-
24
-
-
67650526845
-
Efficacy and safety of albinterferon alfa-2b in combination with ribavirin in treatment naive, chornic hepatitis C genotype 1 (CHC G1) patients [abstract 1041]
-
Zeuzem S, Sulkowski M, Lawitz E, et al. Efficacy and safety of albinterferon alfa-2b in combination with ribavirin in treatment naive, chornic hepatitis C genotype 1 (CHC G1) patients [abstract 1041]. J Hepatol 2009;50(Suppl 1):S377
-
(2009)
J Hepatol
, vol.50
, Issue.SUPPL. 1
-
-
Zeuzem, S.1
Sulkowski, M.2
Lawitz, E.3
-
25
-
-
67650511381
-
Efficacy and safety results of albinterferon alfa-2b in combination with ribavirin in interferon-alfa treatment naive patients with genotype 2 or 3 chronic hepatitis C [abstract 1042]
-
Nelson D, Benhamou Y, Chuang W, et al. Efficacy and safety results of albinterferon alfa-2b in combination with ribavirin in interferon-alfa treatment naive patients with genotype 2 or 3 chronic hepatitis C [abstract 1042]. J Hepatol 2009;50(Suppl 1):S378
-
(2009)
J Hepatol
, vol.50
, Issue.SUPPL. 1
-
-
Nelson, D.1
Benhamou, Y.2
Chuang, W.3
-
26
-
-
77956709917
-
Albinterferon alfa-2b for the treatment of patients with chronic hepatitis C infected with genotypes 2 or 3
-
In press Novartis Europharm Ltd withdraws its marketing uthorisation application for Joulferon (albinterferon alfa-2b). EMA/ 249301/2010, 19 April
-
Nelson DR, Benhamou Y, Chuang WL, et al. Albinterferon alfa-2b for the treatment of patients with chronic hepatitis C infected with genotypes 2 or 3. Gastroenterology In press Novartis Europharm Ltd withdraws its marketing uthorisation application for Joulferon (albinterferon alfa-2b). EMA/ 249301/2010, 19 April 2010
-
(2010)
Gastroenterology
-
-
Nelson, D.R.1
Benhamou, Y.2
Chuang, W.L.3
|