AEE788 potentiates celecoxib-induced growth inhibition and apoptosis in human colon cancer cells

Life Sciences

Volumn 91, Issue 15-16, 2012, Pages 789-799

  Venkatesan, P ^a,d   Bhutia, Sujit K ^b   Singh, Abhay K ^a   Das, Swadesh K ^b   Dash, Rupesh ^b   Chaudhury, Koel ^a   Sarkar, Devanand ^b,c   Fisher, Paul B ^b,c   Mandal, Mahitosh ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY   (India)

^b Virginia Commonwealth University Medical College of Virginia Campus (VCU MCV)   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d PSG INSTITUTE OF ADVANCED STUDIES   (India)

Author keywords

AEE788; Angiogenesis; Apoptosis; Celecoxib; Chemotherapy; Colon cancer; Inhibition; Potentiation

Indexed keywords

6 [4 (4 ETHYL 1 PIPERAZINYLMETHYL)PHENYL] 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; CASPASE 3; CELECOXIB; GELATINASE A; GELATINASE B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN RECEPTOR;

ACTIN FILAMENT; ANGIOGENESIS; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL ASSAY; CELL CYCLE; CELL INVASION; CELL MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN HT29; CELL STRUCTURE; CHORIOALLANTOIS; COLON ADENOCARCINOMA; COLON CANCER; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MICROSCOPY; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

ACTINS; ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHICKENS; COLONIC NEOPLASMS; CYCLOOXYGENASE 2 INHIBITORS; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; PURINES; PYRAZOLES; REACTIVE OXYGEN SPECIES; SULFONAMIDES;

EID: 84867337088     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.08.024     Document Type: Article

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