-
1
-
-
7944221151
-
Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma
-
Abd El-Rehim DM, Pinder SE, Paish CE, Bell JA, Rampaul RS, Blamey RW, Robertson JF, Nicholson RI, Ellis IO. 2004. Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma. Br J Cancer 91: 1532-1542.
-
(2004)
Br J Cancer
, vol.91
, pp. 1532-1542
-
-
Abd El-Rehim, D.M.1
Pinder, S.E.2
Paish, C.E.3
Bell, J.A.4
Rampaul, R.S.5
Blamey, R.W.6
Robertson, J.F.7
Nicholson, R.I.8
Ellis, I.O.9
-
2
-
-
5644302245
-
Future options with trastuzumab for primary systemic and adjuvant therapy
-
Baselga J, Gianni L, Geyer C, Perez EA, Riva A, Jackisch C. 2004. Future options with trastuzumab for primary systemic and adjuvant therapy. Semin Oncol 31: 51-57.
-
(2004)
Semin Oncol
, vol.31
, pp. 51-57
-
-
Baselga, J.1
Gianni, L.2
Geyer, C.3
Perez, E.A.4
Riva, A.5
Jackisch, C.6
-
3
-
-
0037069928
-
Cisplatin-induced activation of the EGF receptor
-
Benhar M, Engelberg D, Levitzki A. 2002. Cisplatin-induced activation of the EGF receptor. Oncogene 21: 8723-8731.
-
(2002)
Oncogene
, vol.21
, pp. 8723-8731
-
-
Benhar, M.1
Engelberg, D.2
Levitzki, A.3
-
4
-
-
24044520039
-
EGFR gene amplification in breast cancer: Correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations
-
Bhargava R, Gerald WL, Li AR, Pan Q, Lal P, Ladanyi M, Chen B. 2005. EGFR gene amplification in breast cancer: Correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations. Mod Pathol 18: 1027-1033.
-
(2005)
Mod Pathol
, vol.18
, pp. 1027-1033
-
-
Bhargava, R.1
Gerald, W.L.2
Li, A.R.3
Pan, Q.4
Lal, P.5
Ladanyi, M.6
Chen, B.7
-
5
-
-
0031028246
-
Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E
-
Bortner DM, Rosenberg MP. 1997. Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E. Mol Cell Biol 17: 453-459.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 453-459
-
-
Bortner, D.M.1
Rosenberg, M.P.2
-
6
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
-
Chou TC, Talalay P. 1984. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22: 27-55.
-
(1984)
Adv Enzyme Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
7
-
-
0037386774
-
Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase
-
Ciardiello F, Caputo R, Damiano V, Troiani T, Vitagliano D, Carlomagno F, Veneziani BM, Fontanini G, Bianco AR, Tortora G. 2003. Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase. Clin Cancer Res 9: 1546-1556.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1546-1556
-
-
Ciardiello, F.1
Caputo, R.2
Damiano, V.3
Troiani, T.4
Vitagliano, D.5
Carlomagno, F.6
Veneziani, B.M.7
Fontanini, G.8
Bianco, A.R.9
Tortora, G.10
-
8
-
-
0029826227
-
Single-agent paclitaxel as first-line treatment of metastatic breast cancer: The British experience
-
Davidson NG. 1996. Single-agent paclitaxel as first-line treatment of metastatic breast cancer: The British experience. Semin Oncol 23: 6-10.
-
(1996)
Semin Oncol
, vol.23
, pp. 6-10
-
-
Davidson, N.G.1
-
9
-
-
14544277088
-
Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients
-
DiGiovanna MP, Stern DF, Edgerton SM, Whalen SG, Moore D II, Thor AD. 2005. Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients. J Clin Oncol 23: 1152-1160.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1152-1160
-
-
DiGiovanna, M.P.1
Stern, D.F.2
Edgerton, S.M.3
Whalen, S.G.4
Moore II, D.5
Thor, A.D.6
-
10
-
-
0027227425
-
Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength
-
DiMilla PA, Stone JA, Quinn JA, Albelda SM, Lauffenburger DA. 1993. Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength. J Cell Biol 122: 729-737.
-
(1993)
J Cell Biol
, vol.122
, pp. 729-737
-
-
DiMilla, P.A.1
Stone, J.A.2
Quinn, J.A.3
Albelda, S.M.4
Lauffenburger, D.A.5
-
11
-
-
0025827797
-
Neural crest cell locomotion induced by antibodies to beta 1 integrins. A tool for studying the roles of substratum molecular avidity and density in migration
-
Duband JL, Dufour S, Yamada SS, Yamada KM, Thiery JP. 1991. Neural crest cell locomotion induced by antibodies to beta 1 integrins. A tool for studying the roles of substratum molecular avidity and density in migration. J Cell Sci 98: 517-532.
-
(1991)
J Cell Sci
, vol.98
, pp. 517-532
-
-
Duband, J.L.1
Dufour, S.2
Yamada, S.S.3
Yamada, K.M.4
Thiery, J.P.5
-
12
-
-
0026505773
-
Molecular and biological properties of the vascular endothelial growth factor family of proteins
-
Ferrara N, Houck K, Jakeman L, Leung DW. 1992. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 13: 18-32.
-
(1992)
Endocr Rev
, vol.13
, pp. 18-32
-
-
Ferrara, N.1
Houck, K.2
Jakeman, L.3
Leung, D.W.4
-
13
-
-
29244461412
-
ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinase activity in combination with radiotherapy
-
Frederick B, Gustafson D, Bianco C, Ciardiello F, Dimery I, Raben D. 2006. ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinase activity in combination with radiotherapy. Int J Radiat Oncol Biol Phys 64: 33-37.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 33-37
-
-
Frederick, B.1
Gustafson, D.2
Bianco, C.3
Ciardiello, F.4
Dimery, I.5
Raben, D.6
-
14
-
-
33745140518
-
Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8
-
Garcia-Martin E, Pizarro RM, Martinez C, Gutierrez-Martin Y, Perez G, Jover R, Agundez JA. 2006. Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8. Pharmacogenomics 7: 575-585.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 575-585
-
-
Garcia-Martin, E.1
Pizarro, R.M.2
Martinez, C.3
Gutierrez-Martin, Y.4
Perez, G.5
Jover, R.6
Agundez, J.A.7
-
15
-
-
0038718522
-
Developing inhibitors of the epidermal growth factor receptor for cancer treatment
-
Grunwald V, Hidalgo M. 2003. Developing inhibitors of the epidermal growth factor receptor for cancer treatment. J Natl Cancer Inst 95: 851-867.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 851-867
-
-
Grunwald, V.1
Hidalgo, M.2
-
16
-
-
2342535824
-
Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells
-
Huh JE, Kang KS, Chae C, Kim HM, Ahn KS, Kim SH. 2004. Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells. Biochem Pharmacol 67: 1811-1818.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1811-1818
-
-
Huh, J.E.1
Kang, K.S.2
Chae, C.3
Kim, H.M.4
Ahn, K.S.5
Kim, S.H.6
-
17
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
Hynes NE, Lane HA. 2005. ERBB receptors and cancer: The complexity of targeted inhibitors. Nat Rev Cancer 5: 341-354.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
18
-
-
0032758072
-
Expression of vascular endothelial growth factor (VEGF) family members in breast cancer
-
Kurebayashi J, Otsuki T, Kunisue H, Mikami Y, Tanaka K, Yamamoto S, Sonoo H. 1999. Expression of vascular endothelial growth factor (VEGF) family members in breast cancer. Jpn J Cancer Res 90: 977-981.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 977-981
-
-
Kurebayashi, J.1
Otsuki, T.2
Kunisue, H.3
Mikami, Y.4
Tanaka, K.5
Yamamoto, S.6
Sonoo, H.7
-
19
-
-
0030045346
-
Cell migration: A physically integrated molecular process
-
Lauffenburger DA, Horwitz AF. 1996. Cell migration: A physically integrated molecular process. Cell 84: 359-369.
-
(1996)
Cell
, vol.84
, pp. 359-369
-
-
Lauffenburger, D.A.1
Horwitz, A.F.2
-
20
-
-
34347218991
-
In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
-
Liang CC, Park AY, Guan JL. 2007. In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2: 329-333.
-
(2007)
Nat Protoc
, vol.2
, pp. 329-333
-
-
Liang, C.C.1
Park, A.Y.2
Guan, J.L.3
-
21
-
-
0041976904
-
Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin/5-fluorouracil
-
Magne N, Fischel JL, Tiffon C, Formento P, Dubreuil A, Renee N, Formento JL, Francoual M, Ciccolini J, Etienne MC, Milano G. 2003. Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin/5-fluorouracil. Br J Cancer 89: 585-592.
-
(2003)
Br J Cancer
, vol.89
, pp. 585-592
-
-
Magne, N.1
Fischel, J.L.2
Tiffon, C.3
Formento, P.4
Dubreuil, A.5
Renee, N.6
Formento, J.L.7
Francoual, M.8
Ciccolini, J.9
Etienne, M.C.10
Milano, G.11
-
22
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: The M77001 study group
-
Marty M, Cognetti F, Maraninchi D, Snyder R, Mauriac L, Tubiana-Hulin M, Chan S, Grimes D, Anton A, Lluch A, Kennedy J, O'Byrne K, Conte P, Green M, Ward C, Mayne K, Extra JM. 2005. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: The M77001 study group. J Clin Oncol 23: 4265-4274.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
Snyder, R.4
Mauriac, L.5
Tubiana-Hulin, M.6
Chan, S.7
Grimes, D.8
Anton, A.9
Lluch, A.10
Kennedy, J.11
O'Byrne, K.12
Conte, P.13
Green, M.14
Ward, C.15
Mayne, K.16
Extra, J.M.17
-
23
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn J, Baselga J. 2003. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 21: 2787-2799.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
24
-
-
0031054990
-
Epidermal growth factor receptor family and chemosensitization
-
Mendelsohn J, Fan Z. 1997. Epidermal growth factor receptor family and chemosensitization. J Natl Cancer Inst 89: 341-343.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 341-343
-
-
Mendelsohn, J.1
Fan, Z.2
-
25
-
-
34948887693
-
ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein
-
Mi Y, Lou L. 2007. ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein. Br J Cancer 97: 934-940.
-
(2007)
Br J Cancer
, vol.97
, pp. 934-940
-
-
Mi, Y.1
Lou, L.2
-
26
-
-
0028174337
-
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
-
Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A. 1994. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367: 576-579.
-
(1994)
Nature
, vol.367
, pp. 576-579
-
-
Millauer, B.1
Shawver, L.K.2
Plate, K.H.3
Risau, W.4
Ullrich, A.5
-
27
-
-
30444445564
-
Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors
-
Morelli MP, Cascone T, Troiani T, De Vita F, Orditura M, Laus G, Eckhardt SG, Pepe S, Tortora G, Ciardiello F. 2005. Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors. Ann Oncol 16: iv61-iv68.
-
(2005)
Ann Oncol
, vol.16
-
-
Morelli, M.P.1
Cascone, T.2
Troiani, T.3
De Vita, F.4
Orditura, M.5
Laus, G.6
Eckhardt, S.G.7
Pepe, S.8
Tortora, G.9
Ciardiello, F.10
-
28
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, Munday NA, Raju SM, Smulson ME, Yamin TT, Yu VL, Miller DK. 1995. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376: 37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
Munday, N.A.11
Raju, S.M.12
Smulson, M.E.13
Yamin, T.T.14
Yu, V.L.15
Miller, D.K.16
-
29
-
-
0032437869
-
Paclitaxel in breast cancer
-
Perez EA. 1998. Paclitaxel in breast cancer. Oncologist 3: 373-389.
-
(1998)
Oncologist
, vol.3
, pp. 373-389
-
-
Perez, E.A.1
-
30
-
-
13844296572
-
Tumor-specific VEGF-A and VEGFR2 in postmenopausal breast cancer patients with long-term follow-up. Implication of a link between VEGF pathway and tamoxifen response
-
Ryden L, Stendahl M, Jonsson H, Emdin S, Bengtsson NO, Landberg G. 2005. Tumor-specific VEGF-A and VEGFR2 in postmenopausal breast cancer patients with long-term follow-up. Implication of a link between VEGF pathway and tamoxifen response. Breast Cancer Res Treat 89: 135-143.
-
(2005)
Breast Cancer Res Treat
, vol.89
, pp. 135-143
-
-
Ryden, L.1
Stendahl, M.2
Jonsson, H.3
Emdin, S.4
Bengtsson, N.O.5
Landberg, G.6
-
31
-
-
77953396511
-
Growth factor receptors and apoptosis regulators: Signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer
-
Sarkar S, Mandal M. 2009. Growth factor receptors and apoptosis regulators: Signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer. Breast Cancer Basic Clin Res 9: 47.
-
(2009)
Breast Cancer Basic Clin Res
, vol.9
, pp. 47
-
-
Sarkar, S.1
Mandal, M.2
-
32
-
-
77953702943
-
ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells
-
Sarkar S, Mazumdar A, Dash R, Sarkar D, Fisher PB, Mandal M. 2010. ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells. Cancer Biol Ther 8: 9.
-
(2010)
Cancer Biol Ther
, vol.8
, pp. 9
-
-
Sarkar, S.1
Mazumdar, A.2
Dash, R.3
Sarkar, D.4
Fisher, P.B.5
Mandal, M.6
-
33
-
-
0038235991
-
Increased expression of cyclin E is associated with an increased resistance to doxorubicin in rat fibroblasts
-
Sgambato A, Camerini A, Pani G, Cangiano R, Faraglia B, Bianchino G, De Bari B, Galeotti T, Cittadini A. 2003. Increased expression of cyclin E is associated with an increased resistance to doxorubicin in rat fibroblasts. Br J Cancer 88: 1956-1962.
-
(2003)
Br J Cancer
, vol.88
, pp. 1956-1962
-
-
Sgambato, A.1
Camerini, A.2
Pani, G.3
Cangiano, R.4
Faraglia, B.5
Bianchino, G.6
De Bari, B.7
Galeotti, T.8
Cittadini, A.9
-
34
-
-
0842268375
-
ZD1839 modulates paclitaxel response in renal cancer by blocking paclitaxel-induced activation of the epidermal growth factor receptor-extracellular signal-regulated kinase pathway
-
Sumitomo M, Asano T, Asakuma J, Horiguchi A, Hayakawa M. 2004. ZD1839 modulates paclitaxel response in renal cancer by blocking paclitaxel-induced activation of the epidermal growth factor receptor-extracellular signal-regulated kinase pathway. Clin Cancer Res 10: 794-801.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 794-801
-
-
Sumitomo, M.1
Asano, T.2
Asakuma, J.3
Horiguchi, A.4
Hayakawa, M.5
-
35
-
-
0036145181
-
EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival
-
Suo Z, Risberg B, Kalsson MG, Willman K, Tierens A, Skovlund E, Nesland JM. 2002. EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival. J Pathol 196: 17-25.
-
(2002)
J Pathol
, vol.196
, pp. 17-25
-
-
Suo, Z.1
Risberg, B.2
Kalsson, M.G.3
Willman, K.4
Tierens, A.5
Skovlund, E.6
Nesland, J.M.7
-
36
-
-
3142774878
-
AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
-
Traxler P, Allegrini PR, Brandt R, Brueggen J, Cozens R, Fabbro D, Grosios K, Lane HA, McSheehy P, Mestan J, Meyer T, Tang C, Wartmann M, Wood J, Caravatti G. 2004. AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res 64: 4931-4941.
-
(2004)
Cancer Res
, vol.64
, pp. 4931-4941
-
-
Traxler, P.1
Allegrini, P.R.2
Brandt, R.3
Brueggen, J.4
Cozens, R.5
Fabbro, D.6
Grosios, K.7
Lane, H.A.8
McSheehy, P.9
Mestan, J.10
Meyer, T.11
Tang, C.12
Wartmann, M.13
Wood, J.14
Caravatti, G.15
-
37
-
-
0029974446
-
F-actin disorganization in apoptotic cell death of cultured rat renal proximal tubular cells
-
Van de Water B, Kruidering M, Nagelkerke JF. 1996. F-actin disorganization in apoptotic cell death of cultured rat renal proximal tubular cells. Am J Physiol 270: F593-F603.
-
(1996)
Am J Physiol
, vol.270
-
-
Van de Water, B.1
Kruidering, M.2
Nagelkerke, J.F.3
-
38
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, Hicklin D, Bohlen P, Schlaeppi JM, Rak J, Kerbel RS. 2001. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis. Cancer Res 61: 5090-5101.
-
(2001)
Cancer Res
, vol.61
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
Hicklin, D.4
Bohlen, P.5
Schlaeppi, J.M.6
Rak, J.7
Kerbel, R.S.8
-
39
-
-
0026083903
-
Tumor angiogenesis and metastasis-Correlation in invasive breast carcinoma
-
Weidner N, Semple JP, Welch WR, Folkman J. 1991. Tumor angiogenesis and metastasis-Correlation in invasive breast carcinoma. N Engl J Med 324: 1-8.
-
(1991)
N Engl J Med
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
40
-
-
0035963435
-
Specific protection against breast cancers by cyclin D1 ablation
-
Yu Q, Geng Y, Sicinski P. 2001. Specific protection against breast cancers by cyclin D1 ablation. Nature 411: 1017-1021.
-
(2001)
Nature
, vol.411
, pp. 1017-1021
-
-
Yu, Q.1
Geng, Y.2
Sicinski, P.3
|