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Volumn 57, Issue 20, 2012, Pages 6429-6444

Time-of-flight neutron rejection to improve prompt gamma imaging for proton range verification: A simulation study

Author keywords

[No Author keywords available]

Indexed keywords

ENERGY THRESHOLDS; GAMMA IMAGING; GAMMA PHOTONS; GAMMA SIGNALS; IN-SITU MONITORING; LONGITUDINAL PROFILE; MONTE CARLO SIMULATION; NEUTRON BACKGROUND; PROMPT GAMMA-RAYS; PROTON CYCLOTRONS; PROTON DOSE; SHIFTING TIME WINDOW; SIMULATION STUDIES; TIME OF FLIGHT; TIME-OF-FLIGHT TECHNIQUES; TIME-RESOLVED;

EID: 84867280532     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/57/20/6429     Document Type: Article
Times cited : (67)

References (54)
  • 1
    • 0038377458 scopus 로고    scopus 로고
    • GEANT4: A simulation toolkit
    • 10.1016/S0168-9002(03)01368-8 0168-9002 A
    • Agostinelli S et al 2003 GEANT4: a simulation toolkit Nucl. Instrum. Methods Phys. Res. A 506 250-303
    • (2003) Nucl. Instrum. Methods Phys. Res. , vol.506 , Issue.3 , pp. 250-303
    • Agostinelli, S.1
  • 2
    • 84855615112 scopus 로고    scopus 로고
    • Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife-edge shaped slit
    • 10.1088/0031-9155/57/2/297 0031-9155
    • Bom V, Joulaeizadeh L and Beekman F 2012 Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife-edge shaped slit Phys. Med. Biol. 57 297-308
    • (2012) Phys. Med. Biol. , vol.57 , Issue.2 , pp. 297-308
    • Bom, V.1    Joulaeizadeh, L.2    Beekman, F.3
  • 3
    • 33745488460 scopus 로고    scopus 로고
    • IMRT: A review and preview
    • 0031-9155 R21
    • Bortfeld T 2006 IMRT: a review and preview Phys. Med. Biol. 51 R363-79
    • (2006) Phys. Med. Biol. , vol.51 , Issue.13
    • Bortfeld, T.1
  • 5
    • 57049129935 scopus 로고    scopus 로고
    • Intensity modulated radiotherapy: Advantages, limitations and future developments
    • 10.2349/biij.2.1.e19 1823-5530
    • Cheung K Y 2006 Intensity modulated radiotherapy: advantages, limitations and future developments Biomed. Imaging Interv. J. 2 19
    • (2006) Biomed. Imaging Interv. J. , vol.2 , Issue.1 , pp. 19
    • Cheung, K.Y.1
  • 6
    • 77951148906 scopus 로고    scopus 로고
    • Hadrontherapy: An Open Source, Geant4-based application for proton-ion therapy studies
    • Cirrone G A P et al 2009 Hadrontherapy: an Open Source, Geant4-based application for proton-ion therapy studies IEEE Nucl. Sci. Symp. Conf. Record pp 4186-9
    • (2009) IEEE Nucl. Sci. Symp. Conf. Record , pp. 4186-4189
    • Cirrone, G.A.P.1
  • 7
    • 79960844502 scopus 로고    scopus 로고
    • Improving time resolution in time-of-flight PET
    • 10.1016/j.nima.2010.11.171 0168-9002 A
    • Conti M 2011 Improving time resolution in time-of-flight PET Nucl. Instrum. Methods Phys. Res. A 648 S194-8
    • (2011) Nucl. Instrum. Methods Phys. Res. , vol.648
    • Conti, M.1
  • 9
    • 79960310626 scopus 로고    scopus 로고
    • Arrays of digital silicon photomultipliers - Intrinsic performance and application to scintillator readout
    • Degenhardt C, Zwaans B, Frach T and De Gruyter R 2010 Arrays of digital silicon photomultipliers - intrinsic performance and application to scintillator readout IEEE Nucl. Sci. Symp. Conf. Record pp 1954-6
    • (2010) IEEE Nucl. Sci. Symp. Conf. Record , pp. 1954-1956
    • Degenhardt, C.1    Zwaans, B.2    Frach, T.3    De Gruyter, R.4
  • 12
    • 84859908339 scopus 로고    scopus 로고
    • The DLED algorithm for timing measurements on large area SiPMs coupled to scintillators
    • 10.1109/TNS.2012.2187927 0018-9499
    • Gola A, Piemonte C and Tarolli A 2012 The DLED algorithm for timing measurements on large area SiPMs coupled to scintillators IEEE Trans. Nucl. Sci. 59 358-65
    • (2012) IEEE Trans. Nucl. Sci. , vol.59 , Issue.2 , pp. 358-365
    • Gola, A.1    Piemonte, C.2    Tarolli, A.3
  • 16
    • 17844399274 scopus 로고    scopus 로고
    • Monte Carlo simulation of a protontherapy platform devoted to ocular melanoma
    • DOI 10.1118/1.1871392
    • Herault J, Iborra N, Serrano B and Chauvel P 2005 Monte Carlo simulation of a protontherapy platform devoted to ocular melanoma Med. Phys. 32 910-9 (Pubitemid 40586775)
    • (2005) Medical Physics , vol.32 , Issue.4 , pp. 910-919
    • Herault, J.1    Iborra, N.2    Serrano, B.3    Chauvel, P.4
  • 17
    • 33748798224 scopus 로고
    • Heavy ion synchrotron for medical use-HIMAC project at NIRS-Japan
    • 10.1016/0375-9474(92)90803-R 0375-9474 A
    • Hiraoa Y et al 1992 Heavy ion synchrotron for medical use-HIMAC project at NIRS-Japan Nucl. Phys. A 538 541-50
    • (1992) Nucl. Phys. , vol.538 , pp. 541-550
    • Hiraoa, Y.1
  • 18
    • 0004179507 scopus 로고
    • Stopping Powers for Electrons and Positrons ICRU Report 37 International Commission On Radiation Units and Measurements (ICRU), Bethesda, MD, USA)
    • ICRU 1984 Stopping Powers for Electrons and Positrons ICRU Report 37 International Commission On Radiation Units and Measurements (ICRU), Bethesda, MD, USA)
    • (1984) ICRU Report
  • 19
    • 70350176156 scopus 로고    scopus 로고
    • Multi-pixel photon counters for TOF PET detector and its challenges
    • 10.1109/TNS.2009.2028075 0018-9499
    • Kim C L, Wang G-C and Dolinsky S 2009 Multi-pixel photon counters for TOF PET detector and its challenges IEEE Trans. Nucl. Sci. 56 2580-5
    • (2009) IEEE Trans. Nucl. Sci. , vol.56 , Issue.5 , pp. 2580-2585
    • Kim, C.L.1    Wang, G.-C.2    Dolinsky, S.3
  • 21
    • 84867271563 scopus 로고    scopus 로고
    • Progress in using prompt gammas for ion range monitoring during hardron-therapy
    • 10.1016/S0167-8140(12)70127-5 0167-8140
    • Krimmer J et al 2012 Progress in using prompt gammas for ion range monitoring during hardron-therapy Radiother. Oncol. 102 S71-2
    • (2012) Radiother. Oncol. , vol.102
    • Krimmer, J.1
  • 23
    • 79960842475 scopus 로고    scopus 로고
    • First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy
    • 10.1016/j.nima.2010.12.092 0168-9002 A
    • Llosá G, Barrio J, Lacasta C, Callier S, Raux L and Taille C L 2010 First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy Nucl. Instrum. Methods Phys. Res. A 648 S96-9
    • (2010) Nucl. Instrum. Methods Phys. Res. , vol.648
    • Llosá, G.1    Barrio, J.2    Lacasta, C.3    Callier, S.4    Raux, L.5    Taille, C.L.6
  • 24
    • 39049164210 scopus 로고    scopus 로고
    • Intensity modulated proton therapy and its sensitivity to treatment uncertainties 1: The potential effects of calculational uncertainties
    • DOI 10.1088/0031-9155/53/4/014, PII S0031915508549608
    • Lomax A J 2008a Intensity modulated proton therapy and its sensitivity to treatment uncertainties 1: the potential effects of calculational uncertainties Phys. Med. Biol. 53 1027-42 (Pubitemid 351238121)
    • (2008) Physics in Medicine and Biology , vol.53 , Issue.4 , pp. 1027-1042
    • Lomax, A.J.1
  • 25
    • 39049126842 scopus 로고    scopus 로고
    • Intensity modulated proton therapy and its sensitivity to treatment uncertainties 2: The potential effects of inter-fraction and inter-field motions
    • DOI 10.1088/0031-9155/53/4/015, PII S0031915508549589
    • Lomax A J 2008b Intensity modulated proton therapy and its sensitivity to treatment uncertainties 2: the potential effects of inter-fraction and inter-field motions Phys. Med. Biol. 53 1043-56 (Pubitemid 351238122)
    • (2008) Physics in Medicine and Biology , vol.53 , Issue.4 , pp. 1043-1056
    • Lomax, A.J.1
  • 26
    • 84867255876 scopus 로고    scopus 로고
    • Mashnik S G 2006 Implementation of CEM03.01 into MCNP6 and its Verification and Validation Running Through MCNP6 CEM03.02 Upgrade Research Note X-3-RN(U)-07-03 Los Alamos National Laboratory
    • (2006) Research Note
    • Mashnik, S.G.1
  • 27
    • 84867248471 scopus 로고    scopus 로고
    • MCNPX 2.3.0 User's Guide Report LA-UR-02-2607 Los Alamos National Laboratory
    • MCNPX 2002 MCNPX 2.3.0 User's Guide Report LA-UR-02-2607 Los Alamos National Laboratory
    • (2002) Report
  • 28
    • 84867278150 scopus 로고    scopus 로고
    • MCNPX MCNPX 2.6.0 Users's Guide Report LA-CP-07-1473 Los Alamos National Laboratory
    • MCNPX 2008 MCNPX 2.6.0 Users's Guide Report LA-CP-07-1473 Los Alamos National Laboratory
    • (2008) Report
  • 29
    • 33750744100 scopus 로고    scopus 로고
    • Prompt gamma measurements for locating the dose falloff region in the proton therapy
    • DOI 10.1063/1.2378561
    • Min C-H, Kim C H, Youn M-Y and Kim J-W 2006 Prompt gamma measurements for locating the dose fall-off region in the proton therapy Appl. Phys. Lett. 89 183517 (Pubitemid 44705775)
    • (2006) Applied Physics Letters , vol.89 , Issue.18 , pp. 183517
    • Min, C.-H.1    Kim, C.H.2    Youn, M.-Y.3    Kim, J.-W.4
  • 30
    • 79551706093 scopus 로고    scopus 로고
    • Monte Carlo patient study on the comparison of prompt gamma and PET imaging for range verification in proton therapy
    • 10.1088/0031-9155/56/4/012 0031-9155
    • Moteabbed M, Espana S and Paganetti H 2011 Monte Carlo patient study on the comparison of prompt gamma and PET imaging for range verification in proton therapy Phys. Med. Biol. 56 1063-82
    • (2011) Phys. Med. Biol. , vol.56 , Issue.4 , pp. 1063-1082
    • Moteabbed, M.1    Espana, S.2    Paganetti, H.3
  • 31
    • 84879910259 scopus 로고    scopus 로고
    • The Heidelberg Ion Therapy (HIT) acceleration coming into operation
    • Ondreka D and Weinrich U 2008 The Heidelberg Ion Therapy (HIT) acceleration coming into operation Proc. Eur. Phys. Soc. Accelerator Group (Genoa, Italy,) pp 979-81
    • (2008) Proc. Eur. Phys. Soc. Accelerator Group , pp. 979-981
    • Ondreka, D.1    Weinrich, U.2
  • 34
    • 78649991101 scopus 로고    scopus 로고
    • Optimizing a three-stage Compton camera for measuring prompt gamma rays emitted during proton radiotherapy
    • 10.1088/0031-9155/55/22/015 0031-9155
    • Peterson S W, Robertson D and Polf J 2010 Optimizing a three-stage Compton camera for measuring prompt gamma rays emitted during proton radiotherapy Phys. Med. Biol. 55 6841-56
    • (2010) Phys. Med. Biol. , vol.55 , Issue.22 , pp. 6841-6856
    • Peterson, S.W.1    Robertson, D.2    Polf, J.3
  • 35
    • 63649163681 scopus 로고    scopus 로고
    • Prompt gamma-ray emission from biological tissues during proton irradiation: A preliminary study
    • 10.1088/0031-9155/54/3/017 0031-9155
    • Polf J C, Peterson S, Ciangaru G, Gillin M and Beddar S 2009a Prompt gamma-ray emission from biological tissues during proton irradiation: a preliminary study Phys. Med. Biol. 54 731-43
    • (2009) Phys. Med. Biol. , vol.54 , Issue.3 , pp. 731-743
    • Polf, J.C.1    Peterson, S.2    Ciangaru, G.3    Gillin, M.4    Beddar, S.5
  • 36
    • 72249111598 scopus 로고    scopus 로고
    • Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation
    • 0031-9155 N02
    • Polf J C, Peterson S, McCleskey M, Roeder B T, Spiridon A, Beddar S and Trache L 2009b Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation Phys. Med. Biol. 54 N519-27
    • (2009) Phys. Med. Biol. , vol.54 , Issue.22
    • Polf, J.C.1    Peterson, S.2    McCleskey, M.3    Roeder, B.T.4    Spiridon, A.5    Beddar, S.6    Trache, L.7
  • 37
    • 79959375306 scopus 로고    scopus 로고
    • Time-based readout of a silicon photomultiplier (SiPM) for time of flight positron emission tomography (TOF-PET)
    • 10.1109/TNS.2011.2119493 0018-9499
    • Powolny F et al 2011 Time-based readout of a silicon photomultiplier (SiPM) for time of flight positron emission tomography (TOF-PET) IEEE Trans. Nucl. Sci. 58 597-604
    • (2011) IEEE Trans. Nucl. Sci. , vol.58 , Issue.3 , pp. 597-604
    • Powolny, F.1
  • 39
    • 79955453982 scopus 로고    scopus 로고
    • Material efficiency studies for a Compton camera designed to measure characteristic prompt gamma rays emitted during proton beam radiotherapy
    • 10.1088/0031-9155/56/10/010 0031-9155
    • Robertson D, Polf J C, Peterson S W, Gillin M T and Beddar S 2011 Material efficiency studies for a Compton camera designed to measure characteristic prompt gamma rays emitted during proton beam radiotherapy Phys. Med. Biol. 56 3047-39
    • (2011) Phys. Med. Biol. , vol.56 , Issue.10 , pp. 3047-3039
    • Robertson, D.1    Polf, J.C.2    Peterson, S.W.3    Gillin, M.T.4    Beddar, S.5
  • 40
    • 79960847098 scopus 로고    scopus 로고
    • Design of Compton camera for 3D prompt-γ imaging during ion beam therapy
    • 10.1016/j.nima.2011.01.069 0168-9002 A
    • Roellinghoff F et al 2011 Design of Compton camera for 3D prompt-γ imaging during ion beam therapy Nucl. Instrum. Methods Phys. Res. A 648 S20-3
    • (2011) Nucl. Instrum. Methods Phys. Res. , vol.648
    • Roellinghoff, F.1
  • 41
    • 84867281895 scopus 로고    scopus 로고
    • Real-time proton beam range monitoring by means of prompt-gamma detection with a collimated camera
    • 10.1016/S0167-8140(12)70203-7 0167-8140
    • Roellinghoff F et al 2012 Real-time proton beam range monitoring by means of prompt-gamma detection with a collimated camera Radiother. Oncol. 102 S120
    • (2012) Radiother. Oncol. , vol.102 , pp. 120
    • Roellinghoff, F.1
  • 43
    • 84858032555 scopus 로고    scopus 로고
    • Monte Carlo calculations of positron emitter yields in proton radiotherapy
    • 10.1088/0031-9155/57/6/1659 0031-9155
    • Seravalli E et al 2012 Monte Carlo calculations of positron emitter yields in proton radiotherapy Phys. Med. Biol. 57 1659-73
    • (2012) Phys. Med. Biol. , vol.57 , Issue.6 , pp. 1659-1673
    • Seravalli, E.1
  • 44
    • 84973120236 scopus 로고    scopus 로고
    • Beam delivery systems for particle radiation therapy: Current status and recent developments
    • 10.1142/S1793626809000211 1793-6268
    • Schippers J M 2009 Beam delivery systems for particle radiation therapy: current status and recent developments Rev. Accel. Sci. Technol. 2 179-200
    • (2009) Rev. Accel. Sci. Technol. , vol.2 , Issue.1 , pp. 179-200
    • Schippers, J.M.1
  • 46
    • 84867270946 scopus 로고    scopus 로고
    • Optimized therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques
    • 10.1016/j.ijrobp.2004.07.443 0360-3016
    • Schulz-Ertner D, Nikoghosyan A, Muenter M, Jäkel O, Karger C and Debus J 2004 Optimized therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques Int. J. Radiat. Oncol. Biol. Phys. 60 S504
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.60 , Issue.1 , pp. 504
    • Schulz-Ertner, D.1    Nikoghosyan, A.2    Muenter, M.3    Jäkel, O.4    Karger, C.5    Debus, J.6
  • 48
    • 84858787696 scopus 로고    scopus 로고
    • The lower bound on the timing resolution of photon counting scintillation detectors
    • 10.1088/0031-9155/57/7/1797 0031-9155
    • Seifert S, van Dam H T and Schaart D R 2012b The lower bound on the timing resolution of photon counting scintillation detectors Phys. Med. Biol. 57 1797-814
    • (2012) Phys. Med. Biol. , vol.57 , Issue.7 , pp. 1797-1814
    • Seifert, S.1    Van Dam, H.T.2    Schaart, D.R.3
  • 49
    • 84867243676 scopus 로고    scopus 로고
    • Prompt gamma imaging with a slit camera for real time range control in proton therapy
    • 10.1016/S0167-8140(12)70065-8 0167-8140
    • Smeets J et al 2012a Prompt gamma imaging with a slit camera for real time range control in proton therapy Radiother. Oncol. 102 S32-3
    • (2012) Radiother. Oncol. , vol.102
    • Smeets, J.1
  • 50
    • 84861115936 scopus 로고    scopus 로고
    • Prompt gamma imaging with a slit camera for real-time range control in proton therapy
    • 10.1088/0031-9155/57/11/3371 0031-9155
    • Smeets J et al 2012b Prompt gamma imaging with a slit camera for real-time range control in proton therapy Phys. Med. Biol. 57 3371-405
    • (2012) Phys. Med. Biol. , vol.57 , Issue.11 , pp. 3371-3405
    • Smeets, J.1
  • 52
    • 77955467857 scopus 로고    scopus 로고
    • Real-time monitoring of the Bragg-peak position in ion therapy by means of single photon detection
    • 10.1007/s00411-010-0276-2 0301-634X
    • Testa M et al 2010 Real-time monitoring of the Bragg-peak position in ion therapy by means of single photon detection Radiat. Environ. Biophys. 49 337-43
    • (2010) Radiat. Environ. Biophys. , vol.49 , Issue.3 , pp. 337-343
    • Testa, M.1
  • 54
    • 84867271565 scopus 로고    scopus 로고
    • private communicatio, Los Alamos National Laboratory
    • Waters L S 2010 private communication, Los Alamos National Laboratory
    • (2010)
    • Waters, L.S.1


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