Material efficiency studies for a Compton camera designed to measure characteristic prompt gamma rays emitted during proton beam radiotherapy

Physics in Medicine and Biology

Volumn 56, Issue 10, 2011, Pages 3047-3059

  Robertson, Daniel ^a,b   Polf, Jerimy C ^a   Peterson, Steve W ^c   Gillin, Michael T ^a,b   Beddar, Sam ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL RESPONSE; BIOLOGICAL TISSUES; BISMUTH GERMANATE; CAMERA DESIGN; COMPTON CAMERA; DETECTION EFFICIENCY; DETECTOR MATERIALS; GAMMA ENERGY; INITIAL STAGES; IRRADIATED TISSUE; LANTHANUM BROMIDE; MATERIAL EFFICIENCY; PROMPT GAMMA-RAYS; PROTON BEAM RADIOTHERAPY; PROTON THERAPY; SPECTROSCOPIC INFORMATION; TREATMENT VERIFICATION; TWO STAGE;

BISMUTH; BROMINE COMPOUNDS; CAMERAS; DETECTORS; GERMANIUM; HISTOLOGY; MATERIALS; OPTIMIZATION; PROTON BEAMS; PROTON IRRADIATION; PROTONS; TISSUE;

GAMMA RAYS;

PROTON;

ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; EQUIPMENT DESIGN; GAMMA RADIATION; HUMAN; INSTRUMENTATION; MONTE CARLO METHOD; RADIATION DOSE; SCINTILLATION CAMERA; SCINTILLATION COUNTING;

EQUIPMENT DESIGN; GAMMA CAMERAS; GAMMA RAYS; HUMANS; MONTE CARLO METHOD; PROTONS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, COMPUTER-ASSISTED; SCINTILLATION COUNTING;

EID: 79955453982     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/56/10/010     Document Type: Article

References (21)

1. Agostinelli S et al 2003 GEANT4-a simulation toolkit Nucl. Instrum. Methods Phys. Res. A 506 250-303
2. Bennett G W, Archambeau J O, Archambeau B E, Meltzer J I and Wingate C L 1978 Visualization and transport of positron emission from proton activation in vivo Science 200 1151-3 (Pubitemid 9087499)
3. Brun R and Rademakers F 1997 ROOT-an object oriented data analysis framework Nucl. Instrum. Methods Phys. Res. A 389 81-6 (Pubitemid 127366056)
4. Clasie B, Wroe A, Kooy H, Depauw N, Flanz J, Paganetti H and Rosenfeld A 2010 Assessment of out-of-field absorbed dose and equivalent dose in proton fields Med. Phys. 37 311-21
5. Frandes M, Zoglauer A, Maxim V and Prost R 2010 A tracking Compton-scattering imaging system for hadron therapy monitoring IEEE Trans. Nucl. Sci. 57 144-50
6. International Commission on Radiation Units and Measurements (ICRU) 2007 Tissue substitutes in radiation dosimetry and measurement ICRU Report No. 44 (Bethesda, MD: ICRU)
7. Min C H, Park J G and Kim C H 2009 Preliminary study for determination of distal dose edge by measuring 90 deg prompt gammas with an array-type prompt gamma detection system Nucl. Technol. 168 89-92
8. National Council on Radiation Protection and Measurements (NCRP) 1971 Protection against neutron radiation NCRP Report No. 38 (Bethesda, MD: NCRP)
9. Peterson S and Polf J 2009 Characterizing secondary gamma fluence from a scanned beam proton therapy nozzle Med. Phys. 36 2613
10. Peterson S, Polf J, Ciangaru G, Frank S J, Bues M and Smith A 2009 Variations in proton scanned beam dose delivery due to uncertainties in magnetic beam steering Med. Phys. 36 3693-702
11. Peterson S, Robertson D and Polf J 2010 Optimizing a three-stage Compton camera for measuring prompt gamma rays emitted during proton radiotherapy Phys. Med. Biol. 55 6841
12. Phillips G W 1995 Gamma-ray imaging with Compton cameras Nucl. Instrum. Methods Phys. Res. B 99 674-7
13. Polf J C, Peterson S, Ciangaru G, Gillin M and Beddar S 2009a Prompt gamma-ray emission from biological tissues during proton irradiation: a preliminary study Phys. Med. Biol. 54 731-43
14. Polf J C, Peterson S, McCleskey M, Roeder B T, Spiridon A, Beddar S and Trache L 2009b Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation Phys. Med. Biol. 54 N519-27
15. Richard M H et al 2009 Design study of a Compton camera for prompt gamma imaging during ion beam therapy Nuclear Science Symp. Conf. Record (NSS/MIC), IEEE 2009 pp 4172-5
16. Schneider U, Agosteo S, Pedroni E and Besserer J 2002 Secondary neutron dose during proton therapy using spot scanning Int. J. Radiat. Oncol. 53 244-51 (Pubitemid 34465830)
17. Smith A et al 2009 The M D Anderson proton therapy system Med. Phys. 36 4068-83
18. Solomon C J and Ott R J 1988 Gamma-ray imaging with silicon detectors-a Compton camera for radionuclide imaging in medicine Nucl. Instrum. Methods Phys. Res. A 273 787-92
19. Sutcliffe J F, Waker A J, Smith A H, Barker M C J and Smith M A 1991 A feasibility study for the simultaneous measurement of carbon, hydrogen and oxygen using pulsed 14.4 Mev neutrons Phys. Med. Biol. 36 87-98
20. Testa E et al 2009 Dose profile monitoring with carbon ions by means of prompt-gamma measurements Nucl. Instrum. Methods Phys. Res. B 267 993-6
21. Yan X, Titt U, Koehler A M and Newhauser W D 2002 Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field Nucl. Instrum. Methods A 476 429-34 (Pubitemid 33149635)