Rhein inhibits integrin-linked kinase expression and regulates matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio in high glucose-induced epithelial-mesenchymal transition of renal tubular cell

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 10, 2012, Pages 1676-1685

  Peng, Linlin ^a   Yang, Jiayi ^a   Ning, Chen ^a   Zhang, Jing ^a   Xiao, Xiangcheng ^a   He, Dan ^a   Wang, Xiaoyuan ^a   Li, Zhiping ^a   Fu, Shuangshuang ^a   Ning, Jianping ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Epithelial mesenchymal transition; Integ rin Linked kinase; Matrix metalloproteinase 9; Rhein; Small interfering RNA

Indexed keywords

GELATINASE B; GLUCOSE; INTEGRIN LINKED KINASE; RHEIN; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UVOMORULIN;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE CELL; MALE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTHRAQUINONES; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; GLUCOSE; HUMANS; KIDNEY TUBULES, PROXIMAL; MATRIX METALLOPROTEINASE 9; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 84867263623     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00107     Document Type: Article

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